IL103568A0 - Quinoline derivatives,process for their preparation and their therapeutic applications - Google Patents
Quinoline derivatives,process for their preparation and their therapeutic applicationsInfo
- Publication number
- IL103568A0 IL103568A0 IL103568A IL10356892A IL103568A0 IL 103568 A0 IL103568 A0 IL 103568A0 IL 103568 A IL103568 A IL 103568A IL 10356892 A IL10356892 A IL 10356892A IL 103568 A0 IL103568 A0 IL 103568A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- alkoxy
- aryl
- independently
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9113240A FR2683819B1 (fr) | 1991-10-28 | 1991-10-28 | Derives de quinoleine, leur procede de preparation et leur application en therapeutique. |
Publications (1)
Publication Number | Publication Date |
---|---|
IL103568A0 true IL103568A0 (en) | 1993-03-15 |
Family
ID=9418349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL103568A IL103568A0 (en) | 1991-10-28 | 1992-10-27 | Quinoline derivatives,process for their preparation and their therapeutic applications |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0540400B1 (xx) |
JP (1) | JPH05239053A (xx) |
KR (1) | KR930007935A (xx) |
CN (1) | CN1073171A (xx) |
AT (1) | ATE126798T1 (xx) |
AU (1) | AU651740B2 (xx) |
CA (1) | CA2081537A1 (xx) |
CZ (1) | CZ324292A3 (xx) |
DE (1) | DE69204252T2 (xx) |
FI (1) | FI924869A (xx) |
FR (1) | FR2683819B1 (xx) |
HU (1) | HUT62883A (xx) |
IL (1) | IL103568A0 (xx) |
MX (1) | MX9206169A (xx) |
NO (1) | NO924138L (xx) |
NZ (1) | NZ244892A (xx) |
PL (1) | PL296369A1 (xx) |
ZA (1) | ZA928297B (xx) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5478832A (en) * | 1992-05-08 | 1995-12-26 | The Green Cross Corporation | Quinoline compounds |
IT1255461B (it) * | 1992-07-28 | 1995-11-02 | Luso Farmaco Inst | Eteri di imidazoli ad attivita' a ii antagonista |
FR2699174B1 (fr) * | 1992-12-14 | 1995-01-20 | Synthelabo | Dérivés de 3-(quinoléin-6-yl-méthyl)-4H-imidazol-4-one, leur préparation et leur application en thérapeutique. |
FR2710914B1 (fr) * | 1993-10-04 | 1995-11-24 | Synthelabo | Dérivés de 2-[2-(tétrazol-5-yl)phényl]-1,2-dihydroquinoléine, leur préparation et leur utilisation comme intermédiaires de synthèse. |
FR2716196B1 (fr) * | 1994-02-16 | 1996-04-05 | Synthelabo | Dérivés de 8-[2-(1H-tétrazol-5-yl) phényl] quinoléine, leur préparation et leur application en thérapeutique. |
JPH09202774A (ja) | 1996-01-25 | 1997-08-05 | Green Cross Corp:The | 2−アリールキノリン類およびその製造方法 |
DE19706161A1 (de) * | 1997-02-17 | 1998-08-20 | Oswald Hartmut Prof Dr Med | Verwendung von Cyaninen, Isocyaninen und Pseudoisocyaninen als Diuretika |
KR100744826B1 (ko) * | 2006-04-05 | 2007-08-01 | 한국화학연구원 | 이미다졸기가 치환된 퀴놀리논 유도체 |
AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CN103804349A (zh) * | 2012-11-01 | 2014-05-21 | 杨子娇 | 一类治疗青光眼的化合物及其用途 |
WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
CN108558750B (zh) * | 2018-07-11 | 2021-01-05 | 武汉工程大学 | 无溶剂法合成3-硝基喹啉衍生物的工艺 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them |
MX9200299A (es) * | 1991-02-07 | 1992-12-01 | Roussel Uclaf | Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen. |
DE4117750A1 (de) * | 1991-05-30 | 1992-12-24 | Bayer Ag | Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
DE59208448D1 (de) * | 1991-08-15 | 1997-06-12 | Ciba Geigy Ag | N-Acyl-N-Heterocyclyl- oder Naphthylalkyl-Aminosäuren als Angiotensin II Antagonisten |
-
1991
- 1991-10-28 FR FR9113240A patent/FR2683819B1/fr not_active Expired - Fee Related
-
1992
- 1992-10-22 EP EP92402879A patent/EP0540400B1/fr not_active Revoked
- 1992-10-22 AT AT92402879T patent/ATE126798T1/de active
- 1992-10-22 DE DE69204252T patent/DE69204252T2/de not_active Revoked
- 1992-10-27 NO NO92924138A patent/NO924138L/no unknown
- 1992-10-27 IL IL103568A patent/IL103568A0/xx unknown
- 1992-10-27 HU HU9203374A patent/HUT62883A/hu unknown
- 1992-10-27 PL PL29636992A patent/PL296369A1/xx unknown
- 1992-10-27 CZ CS923242A patent/CZ324292A3/cs unknown
- 1992-10-27 FI FI924869A patent/FI924869A/fi not_active Application Discontinuation
- 1992-10-27 AU AU27348/92A patent/AU651740B2/en not_active Ceased
- 1992-10-27 ZA ZA928297A patent/ZA928297B/xx unknown
- 1992-10-27 KR KR1019920019802A patent/KR930007935A/ko not_active Application Discontinuation
- 1992-10-27 JP JP4288458A patent/JPH05239053A/ja active Pending
- 1992-10-27 MX MX9206169A patent/MX9206169A/es unknown
- 1992-10-27 CN CN92113784A patent/CN1073171A/zh active Pending
- 1992-10-27 CA CA002081537A patent/CA2081537A1/en not_active Abandoned
- 1992-10-27 NZ NZ244892A patent/NZ244892A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
KR930007935A (ko) | 1993-05-20 |
FR2683819B1 (fr) | 1994-02-11 |
AU651740B2 (en) | 1994-07-28 |
ATE126798T1 (de) | 1995-09-15 |
AU2734892A (en) | 1993-04-29 |
PL296369A1 (en) | 1993-05-31 |
DE69204252T2 (de) | 1996-04-18 |
DE69204252D1 (de) | 1995-09-28 |
CA2081537A1 (en) | 1993-04-29 |
MX9206169A (es) | 1993-07-01 |
CZ324292A3 (en) | 1993-09-15 |
NO924138L (no) | 1993-04-29 |
HUT62883A (en) | 1993-06-28 |
NZ244892A (en) | 1994-06-27 |
NO924138D0 (no) | 1992-10-27 |
EP0540400A1 (fr) | 1993-05-05 |
FI924869A0 (fi) | 1992-10-27 |
FR2683819A1 (fr) | 1993-05-21 |
FI924869A (fi) | 1993-04-29 |
EP0540400B1 (fr) | 1995-08-23 |
HU9203374D0 (en) | 1993-01-28 |
JPH05239053A (ja) | 1993-09-17 |
ZA928297B (en) | 1993-05-07 |
CN1073171A (zh) | 1993-06-16 |
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