IE812075L - Composition - Google Patents

Composition

Info

Publication number
IE812075L
IE812075L IE812075A IE207581A IE812075L IE 812075 L IE812075 L IE 812075L IE 812075 A IE812075 A IE 812075A IE 207581 A IE207581 A IE 207581A IE 812075 L IE812075 L IE 812075L
Authority
IE
Ireland
Prior art keywords
composition
admixture
solid
pharmaceutical composition
surface area
Prior art date
Application number
IE812075A
Other versions
IE51549B1 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6111496&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE812075(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE812075L publication Critical patent/IE812075L/en
Publication of IE51549B1 publication Critical patent/IE51549B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

1. A solid pharmaceutical composition containing as the active ingredient nifedipine crystals with a specific surface area of 0,5 to 6 m**2 /g, in admixture with a solid diluent. [EP0047899A1]
IE2075/81A 1980-09-09 1981-09-08 Solid medicament formulations containing nifedipine,and processes for their preparation IE51549B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803033919 DE3033919A1 (en) 1980-09-09 1980-09-09 SOLID PHARMACEUTICAL PREPARATIONS CONTAINING NIFEDIPINE AND METHOD FOR THE PRODUCTION THEREOF

Publications (2)

Publication Number Publication Date
IE812075L true IE812075L (en) 1982-03-09
IE51549B1 IE51549B1 (en) 1987-01-07

Family

ID=6111496

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2075/81A IE51549B1 (en) 1980-09-09 1981-09-08 Solid medicament formulations containing nifedipine,and processes for their preparation

Country Status (20)

Country Link
EP (1) EP0047899B2 (en)
JP (1) JPS5914446B2 (en)
AR (1) AR226377A1 (en)
AT (1) ATE5761T1 (en)
AU (1) AU558331B2 (en)
CA (1) CA1180277A (en)
DD (1) DD201974A5 (en)
DE (2) DE3033919A1 (en)
DK (1) DK154326C (en)
FI (1) FI72648B (en)
GR (1) GR78237B (en)
HU (1) HU184879B (en)
IE (1) IE51549B1 (en)
IL (1) IL63749A (en)
NO (1) NO157368B (en)
NZ (1) NZ198285A (en)
PH (1) PH24097A (en)
PL (1) PL232951A1 (en)
PT (1) PT73603B (en)
ZA (1) ZA816213B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264446A (en) * 1980-09-09 1993-11-23 Bayer Aktiengesellschaft Solid medicament formulations containing nifedipine, and processes for their preparation
JPS5846019A (en) * 1981-09-14 1983-03-17 Kanebo Ltd Nifedipine preparation with prolonged action
DE3222367A1 (en) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
JPS59101423A (en) * 1982-12-02 1984-06-12 Takada Seiyaku Kk Novel solid pharmaceutical preparation of nifedipine
US4529733A (en) * 1983-04-06 1985-07-16 Merrell Dow Pharmaceuticals Inc. Antihypertensive 3-furoyl-1,4-dihydropyridines
DE3318649A1 (en) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen TWO-PHASE FORMULATION
NL194389C (en) * 1984-06-14 2002-03-04 Novartis Ag Process for preparing a solid dispersion of a pharmaceutically active agent that has low water solubility in a solid matrix of a water-soluble polyalkylene glycol as a carrier.
IT1178511B (en) * 1984-09-14 1987-09-09 Pharmatec Spa PROCEDURE FOR THE PREPARATION OF A SOLID FORM FOR ORAL USE BASED ON NIFEDIPINE WITH RELEASE
IT1187751B (en) * 1985-10-15 1987-12-23 Eurand Spa PROCEDURE FOR THE PREPARATION OF SOLID FORMULATIONS OF NIFEDIPINE WITH HIGH BIO AVAILABILITY AND WITH PROLONGED EFFECT AND FORMULATIONS SO OBTAINED
US4940556A (en) * 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
US5198226A (en) * 1986-01-30 1993-03-30 Syntex (U.S.A.) Inc. Long acting nicardipine hydrochloride formulation
CH673947A5 (en) * 1986-09-23 1990-04-30 Sandoz Ag
JPS6464659A (en) * 1987-09-03 1989-03-10 Kenbi Kogaku Kenkyusho Kk Preparation of safe and effective powder formulation
SE8703881D0 (en) * 1987-10-08 1987-10-08 Haessle Ab NEW PHARMACEUTICAL PREPARATION
DE3814532A1 (en) * 1988-04-29 1989-11-09 Bayer Ag DHP-RETARD-PREPARATION
JPH0298550U (en) * 1989-01-25 1990-08-06
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
US5271944A (en) * 1991-04-05 1993-12-21 Biofor, Ltd. Pharmacologically enhanced formulations
DE4130173A1 (en) * 1991-09-11 1993-03-18 Bayer Ag PHARMACEUTICAL PREPARATIONS WITH A SPECIAL CRYSTAL MODIFICATION OF 1,4-DIHYDRO-2,6-DIMETHYL-4- (3-NITROPHENYL) -3,5-PYRIDINDICARBONIC ACID ISOPROPYL- (2-METHOXYETHYL) ESTER
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US6726930B1 (en) 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5543099A (en) * 1994-09-29 1996-08-06 Hallmark Pharmaceutical, Inc. Process to manufacture micronized nifedipine granules for sustained release medicaments
DK0800392T3 (en) * 1994-12-29 2002-03-18 Shire Deutschland Gmbh & Co Kg Pharmaceutical compositions containing nifedipine and its method of preparation
JP3220373B2 (en) 1995-11-28 2001-10-22 バイエル薬品株式会社 Long-acting nifedipine preparation
KR100321489B1 (en) 1996-07-08 2002-10-09 에드워드 멘델 컴파니 인코포레이티드 Sustained release matrix for high-dose insoluble drugs
IT1284604B1 (en) * 1996-09-27 1998-05-21 Roberto Valducci CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION CONTAINING NIFEDIPINE AS THE ACTIVE SUBSTANCE
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
IL143375A0 (en) 1999-09-30 2002-04-21 Penwest Pharmaceuticals Co Sustained release matrix systems for highly soluble drugs
RU2378272C2 (en) 2004-07-30 2010-01-10 Торрент Фармасьютикалз Лимитед Nebivolol and pharmaceutically acceptable salts thereof, method of producing said salts and nebivolol pharmaceutical compositions
DE102004062475A1 (en) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Solid, orally administrable, modified release pharmaceutical dosage forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3330727A (en) * 1960-04-19 1967-07-11 Glaxo Lab Ltd Griseofulvin with high specific surface area
US3401221A (en) * 1964-08-25 1968-09-10 Norwich Pharma Co Treatment of urinary tract infection
DE2348334C2 (en) * 1973-09-26 1982-11-11 Boehringer Mannheim Gmbh, 6800 Mannheim New form of preparation of N-4- [2- (5-chloro-2-methoxybenzamido) ethyl] -phenyl-sulfonyl-N'-cyclohexylurea
DE2400819C2 (en) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Process for the production of solid preparations of poorly soluble active pharmaceutical ingredients in extremely fine distribution
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
JPS55129221A (en) * 1979-03-29 1980-10-06 Kaken Pharmaceut Co Ltd Preparation of oral preparation containing hardly soluble medicine
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material

Also Published As

Publication number Publication date
NZ198285A (en) 1984-04-27
PH24097A (en) 1990-03-05
IE51549B1 (en) 1987-01-07
FI812758L (en) 1982-03-10
DE3161838D1 (en) 1984-02-09
DD201974A5 (en) 1983-08-24
AU558331B2 (en) 1987-01-29
FI72648B (en) 1987-03-31
GR78237B (en) 1984-09-26
IL63749A (en) 1984-06-29
DK154326C (en) 1995-03-13
HU184879B (en) 1984-10-29
DE3033919A1 (en) 1982-04-22
DK154326B (en) 1988-11-07
EP0047899A1 (en) 1982-03-24
ZA816213B (en) 1982-09-29
NO157368B (en) 1987-11-30
NO812879L (en) 1982-03-10
EP0047899B2 (en) 1996-02-28
JPS5914446B2 (en) 1984-04-04
AU7506381A (en) 1982-03-18
CA1180277A (en) 1985-01-02
AR226377A1 (en) 1982-06-30
EP0047899B1 (en) 1984-01-04
PT73603B (en) 1982-11-10
DK396381A (en) 1982-03-10
JPS5750913A (en) 1982-03-25
IL63749A0 (en) 1981-12-31
ATE5761T1 (en) 1984-01-15
PT73603A (en) 1981-09-01
PL232951A1 (en) 1982-10-11

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Legal Events

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MK9A Patent expired