ID22074A - Senyawa-senyawa baru dengan efek analgesik - Google Patents

Senyawa-senyawa baru dengan efek analgesik

Info

Publication number
ID22074A
ID22074A IDW990508A ID990508A ID22074A ID 22074 A ID22074 A ID 22074A ID W990508 A IDW990508 A ID W990508A ID 990508 A ID990508 A ID 990508A ID 22074 A ID22074 A ID 22074A
Authority
ID
Indonesia
Prior art keywords
new compounds
analgesic effects
analgesic
effects
compounds
Prior art date
Application number
IDW990508A
Other languages
English (en)
Indonesian (id)
Inventor
Daniel Delorme
Edward Roberis
Zhongyong Wei
Original Assignee
Astra Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9604785A external-priority patent/SE9604785D0/xx
Priority claimed from SE9702535A external-priority patent/SE9702535D0/xx
Application filed by Astra Pharma Inc filed Critical Astra Pharma Inc
Publication of ID22074A publication Critical patent/ID22074A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW990508A 1996-12-20 1997-12-09 Senyawa-senyawa baru dengan efek analgesik ID22074A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9604785A SE9604785D0 (sv) 1996-12-20 1996-12-20 New compounds
SE9702535A SE9702535D0 (sv) 1997-07-01 1997-07-01 New compounds

Publications (1)

Publication Number Publication Date
ID22074A true ID22074A (id) 1999-09-02

Family

ID=26662830

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990508A ID22074A (id) 1996-12-20 1997-12-09 Senyawa-senyawa baru dengan efek analgesik

Country Status (29)

Country Link
US (5) US6187792B1 (fr)
EP (1) EP0946511B1 (fr)
JP (1) JP4324652B2 (fr)
KR (1) KR100549144B1 (fr)
CN (2) CN1146540C (fr)
AR (1) AR010376A1 (fr)
AT (1) ATE296288T1 (fr)
AU (1) AU737999B2 (fr)
BR (1) BR9714055B1 (fr)
CA (1) CA2274074C (fr)
CZ (1) CZ295557B6 (fr)
DE (1) DE69733362T2 (fr)
EE (1) EE03824B1 (fr)
ES (1) ES2241060T3 (fr)
HK (1) HK1022689A1 (fr)
HU (1) HU226724B1 (fr)
ID (1) ID22074A (fr)
IL (2) IL130535A0 (fr)
IS (1) IS2210B (fr)
MY (1) MY119403A (fr)
NO (1) NO313670B1 (fr)
NZ (1) NZ336029A (fr)
PL (1) PL189196B1 (fr)
PT (1) PT946511E (fr)
RU (1) RU2193029C2 (fr)
SK (1) SK283211B6 (fr)
TR (1) TR199901417T2 (fr)
TW (1) TW548271B (fr)
WO (1) WO1998028275A1 (fr)

Families Citing this family (69)

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SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
TW548271B (en) 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
US7361666B2 (en) 1999-05-25 2008-04-22 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
US6635661B2 (en) 2000-05-25 2003-10-21 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
JP2003500392A (ja) * 1999-05-25 2003-01-07 セプラコール, インク. 複素環式鎮痛性化合物およびその使用方法
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
US6306876B1 (en) 1999-12-22 2001-10-23 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(8-azabicyclo[3.2.1]octan-3-yl)]aminobenzoic acid derivatives
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WO2001092226A1 (fr) 2000-05-25 2001-12-06 Sepracor, Inc. Composes analgesiques heterocycliques et technique d'utilisation de ceux-ci
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SE0101770D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
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Also Published As

Publication number Publication date
EE9900256A (et) 1999-12-15
NZ336029A (en) 2001-03-30
SK76299A3 (en) 1999-11-08
IL130535A0 (en) 2000-06-01
AU5351298A (en) 1998-07-17
HUP0000610A3 (en) 2000-10-30
CN1146540C (zh) 2004-04-21
NO993022L (no) 1999-08-20
US20040171612A1 (en) 2004-09-02
US6693117B2 (en) 2004-02-17
CZ219999A3 (cs) 1999-11-17
BR9714055A (pt) 2000-05-09
PL189196B1 (pl) 2005-07-29
IS2210B (is) 2007-02-15
MY119403A (en) 2005-05-31
PT946511E (pt) 2005-09-30
HK1022689A1 (en) 2000-08-18
TW548271B (en) 2003-08-21
CA2274074C (fr) 2006-07-11
IS5071A (is) 1999-06-07
NO313670B1 (no) 2002-11-11
NO993022D0 (no) 1999-06-18
IL130535A (en) 2006-04-10
WO1998028275A1 (fr) 1998-07-02
RU2193029C2 (ru) 2002-11-20
JP4324652B2 (ja) 2009-09-02
ES2241060T3 (es) 2005-10-16
DE69733362T2 (de) 2006-02-02
HUP0000610A2 (hu) 2000-09-28
SK283211B6 (sk) 2003-03-04
CN1246111A (zh) 2000-03-01
AR010376A1 (es) 2000-06-07
HU226724B1 (en) 2009-08-28
TR199901417T2 (xx) 1999-10-21
EE03824B1 (et) 2002-08-15
BR9714055B1 (pt) 2010-02-23
DE69733362D1 (de) 2005-06-30
US20010021715A1 (en) 2001-09-13
KR100549144B1 (ko) 2006-02-03
ATE296288T1 (de) 2005-06-15
EP0946511A1 (fr) 1999-10-06
CN1524852A (zh) 2004-09-01
JP2001507350A (ja) 2001-06-05
KR20000069599A (ko) 2000-11-25
AU737999B2 (en) 2001-09-06
US20080176903A1 (en) 2008-07-24
US6455545B2 (en) 2002-09-24
PL334374A1 (en) 2000-02-28
CZ295557B6 (cs) 2005-08-17
US6187792B1 (en) 2001-02-13
CN100519528C (zh) 2009-07-29
US20030149023A1 (en) 2003-08-07
CA2274074A1 (fr) 1998-07-02
EP0946511B1 (fr) 2005-05-25
US7312336B2 (en) 2007-12-25

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