PT799819E - Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico - Google Patents

Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico

Info

Publication number: PT799819E
Authority: PT; Portugal
Prior art keywords: phenylcylcalcal; dimethylaminomethyl; analgesic effect; ene compounds; ene
Prior art date: 1996-03-13

Application number

PT97102923T

Other languages

English (en)

Inventor

Werner Alfred Strassb Wolfgang

Josef Friderichs Dr Elmar

Helmut Heinrich Buschmann

Babette-Yvonne Koegel

Original Assignee

Gruenenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-13

Filing date

1997-02-22

Publication date

2003-01-31

1997-02-22 Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh

2003-01-31 Publication of PT799819E publication Critical patent/PT799819E/pt

Links

230000000202 analgesic effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/28—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by unsaturated carbon chains
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT97102923T 1996-03-13 1997-02-22 Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico PT799819E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19609847A DE19609847A1 (de)	1996-03-13	1996-03-13	Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe

Publications (1)

Publication Number	Publication Date
PT799819E true PT799819E (pt)	2003-01-31

Family

ID=7788151

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PT99119109T PT983995E (pt)	1996-03-13	1997-02-22	Compostos de dimetil-(3-aril-but-3-enil)amina como substancias activas farmaceuticas
PT97102923T PT799819E (pt)	1996-03-13	1997-02-22	Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico
PT00116745T PT1069106E (pt)	1996-03-13	1997-02-22	Compostos de dimetil-(3-aril-but-3-enil)amina de formula i com efeito analgesico

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PT99119109T PT983995E (pt)	1996-03-13	1997-02-22	Compostos de dimetil-(3-aril-but-3-enil)amina como substancias activas farmaceuticas

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT00116745T PT1069106E (pt)	1996-03-13	1997-02-22	Compostos de dimetil-(3-aril-but-3-enil)amina de formula i com efeito analgesico

Country Status (28)

Country	Link
US (1)	US5811582A (pt)
EP (4)	EP0799819B1 (pt)
JP (2)	JP4205182B2 (pt)
KR (2)	KR100538662B1 (pt)
CN (1)	CN1157366C (pt)
AR (1)	AR008991A1 (pt)
AT (3)	ATE223888T1 (pt)
AU (1)	AU725430B2 (pt)
BR (1)	BR9700369B1 (pt)
CA (1)	CA2199679C (pt)
CO (1)	CO4520279A1 (pt)
CZ (1)	CZ293971B6 (pt)
DE (4)	DE19609847A1 (pt)
DK (3)	DK0983995T3 (pt)
ES (3)	ES2213526T3 (pt)
HK (2)	HK1026197A1 (pt)
HU (1)	HU224819B1 (pt)
IL (1)	IL120430A (pt)
NO (1)	NO308294B1 (pt)
NZ (1)	NZ314384A (pt)
PE (1)	PE55798A1 (pt)
PL (1)	PL186050B1 (pt)
PT (3)	PT983995E (pt)
RU (1)	RU2167146C2 (pt)
SI (3)	SI1069106T1 (pt)
SK (1)	SK284328B6 (pt)
UA (1)	UA55373C2 (pt)
ZA (1)	ZA972147B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4426245A1 (de) *	1994-07-23	1996-02-22	Gruenenthal Gmbh	1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE19732928C2 (de) *	1997-07-31	2000-05-18	Gruenenthal Gmbh	Verwendung substituierter Imidazolidin-2,4-dion-Verbindungen als Schmerzmittel
DE19830105C1 (de) *	1998-07-06	2000-02-17	Gruenenthal Gmbh	Acridinderivate
ES2141688B1 (es) *	1998-11-06	2001-02-01	Vita Invest Sa	Nuevos esteres derivados de compuestos fenil-ciclohexil sustituidos.
DE10000311A1 (de) *	2000-01-05	2001-07-12	Gruenenthal Gmbh	Aminomethyl-Phonyl-Cyclohexanonderivate
DE10025948A1 (de) *	2000-05-26	2001-11-29	Gruenenthal Gmbh	Wirkstoffkombination
DE10049481A1 (de) *	2000-09-29	2002-05-02	Gruenenthal Gmbh	Substituierte C-Cyclohexylmethylamin-Derivate
DE10049483A1 (de) *	2000-09-29	2002-05-02	Gruenenthal Gmbh	Substituierte 1-Aminobutan-3-ol-Derivate
DE10059413A1 (de) *	2000-11-30	2002-06-20	Gruenenthal Gmbh	Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
US20050176790A1 (en)	2001-02-28	2005-08-11	Johannes Bartholomaus	Pharmaceutical salts
WO2002074241A2 (en) *	2001-03-16	2002-09-26	Dmi Biosciences Inc.	Method of delaying ejaculation
DE10132747A1 (de) *	2001-07-05	2003-01-23	Gruenenthal Gmbh	Substituierte 1-Aryl-but-3-enylamin- und 1-Aryl-but-2-enylaminverbindungen
DE10146275A1 (de) *	2001-09-18	2003-04-24	Gruenenthal Gmbh	Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
PE20030527A1 (es)	2001-10-24	2003-07-26	Gruenenthal Chemie	Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
DE10224624A1 (de) *	2002-05-30	2003-12-11	Gruenenthal Gmbh	Metabolite und Prodrugs von 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol
DE10225315A1 (de) *	2002-06-06	2003-12-24	Gruenenthal Gmbh	Wirkstoffsalze und Ester von 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl- pentan-3-ol und 3-(3-Dimethylamino-1-ethyl-1-hydroxy-2-methyl- propyl)-phenol
DE10261091A1 (de)	2002-12-20	2004-07-01	Grünenthal GmbH	Gesättigte und ungesättigte Heteroarylcycloalkylmethyl-Amine
DE10326097A1 (de) *	2003-06-06	2005-01-05	Grünenthal GmbH	Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen
DE10328316A1 (de) *	2003-06-23	2005-01-20	Grünenthal GmbH	Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE102004034619A1 (de) *	2004-07-16	2006-02-23	Grünenthal GmbH	Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer
DE102005033732B4 (de)	2005-05-27	2014-02-13	Grünenthal GmbH	Trennung stereoisomerer N,N-Dialkylamino-2-alkyl-3-hydroxy-3-phenyl-alkane
DE102005052588A1 (de)	2005-11-02	2007-05-10	Grünenthal GmbH	Verfahren zur Herstellung substituierter Dimethyl-(3-aryl-butyl)-amin-Verbindungen mittels homogener Katalyse
DE102005061429A1 (de) *	2005-12-22	2007-06-28	Grünenthal GmbH	Substituierte Oxazol-Derivate
CA2656696C (en) *	2006-07-24	2013-06-11	Janssen Pharmaceutica N.V.	Preparation of (2r,3r)-3-(3-methoxyphenyl)-n,n,2-trimethylpentanamine
TWI496762B (zh) *	2006-07-24	2015-08-21		製備（１ｒ，２ｒ）-３-（３-二甲胺基-１-乙基-２-甲基-丙基）-酚之方法
CN101948397A (zh) *	2010-09-07	2011-01-19	天津泰普药品科技发展有限公司	镇痛药他喷他多重要中间体的制备方法
WO2012038974A1 (en) *	2010-09-20	2012-03-29	Ind-Swift Laboratories Limited	Process for preparing l-phenyl-3-dimethylaminopropane derivative
EP2674414A1 (en)	2012-06-15	2013-12-18	Siegfried AG	Method for the preparation of 1-aryl-1-alkyl-3-dialkylaminopropane compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1518663A1 (de) *	1965-08-02	1969-12-18	Gruenenthal Chemie	Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung
US3652589A (en) *	1967-07-27	1972-03-28	Gruenenthal Chemie	1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US3978129A (en) *	1972-01-28	1976-08-31	A. H. Robins Company, Incorporated	Alkenyl- and alkanylamines
GB1502635A (en) *	1974-02-27	1978-03-01	Schering Ag	Process for splitting steroid ethers
DE2409990C2 (de) *	1974-02-27	1982-11-25	Siemens AG, 1000 Berlin und 8000 München	Meßwandler für Hochspannungsschaltanlagen mit Metallkapselung
JPS598259B2 (ja) *	1976-01-01	1984-02-23	武田薬品工業株式会社	新規シクロヘキセン誘導体
US4173649A (en) *	1978-02-27	1979-11-06	E. R. Squibb & Sons, Inc.	5-Phenyl-2,4-pentadien-1-amines and method for inhibiting prostaglandin dehydrogenase
FR2559765B1 (fr) *	1984-02-16	1986-06-13	Rhone Poulenc Sante	Nouveaux derives de la phenyl-3 propene-2 amine, leur preparation et les medicaments qui les contiennent
IT1213219B (it) *	1984-09-28	1989-12-14	Consiglio Nazionale Ricerche	Derivati amminoalchilnaftalenici ad attivita' farmacologica.
US5430044A (en) *	1987-02-06	1995-07-04	Fisons Corporation	Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties
SE9202218D0 (sv) *	1992-07-22	1992-07-22	Kabi Pharmacia Ab	Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation
DE4426245A1 (de) *	1994-07-23	1996-02-22	Gruenenthal Gmbh	1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung

1996
- 1996-03-13 DE DE19609847A patent/DE19609847A1/de not_active Withdrawn
1997
- 1997-02-22 SI SI9730618T patent/SI1069106T1/xx unknown
- 1997-02-22 EP EP97102923A patent/EP0799819B1/de not_active Expired - Lifetime
- 1997-02-22 ES ES00116745T patent/ES2213526T3/es not_active Expired - Lifetime
- 1997-02-22 DE DE59708160T patent/DE59708160D1/de not_active Expired - Lifetime
- 1997-02-22 EP EP99119109A patent/EP0983995B1/de not_active Expired - Lifetime
- 1997-02-22 PT PT99119109T patent/PT983995E/pt unknown
- 1997-02-22 DK DK99119109T patent/DK0983995T3/da active
- 1997-02-22 DE DE59711477T patent/DE59711477D1/de not_active Expired - Lifetime
- 1997-02-22 SI SI9730428T patent/SI0799819T1/xx unknown
- 1997-02-22 EP EP99119108A patent/EP0983994A3/de not_active Withdrawn
- 1997-02-22 DK DK97102923T patent/DK0799819T3/da active
- 1997-02-22 PT PT97102923T patent/PT799819E/pt unknown
- 1997-02-22 PT PT00116745T patent/PT1069106E/pt unknown
- 1997-02-22 DE DE59711267T patent/DE59711267D1/de not_active Expired - Lifetime
- 1997-02-22 AT AT97102923T patent/ATE223888T1/de active
- 1997-02-22 ES ES99119109T patent/ES2218924T3/es not_active Expired - Lifetime
- 1997-02-22 SI SI9730653T patent/SI0983995T1/xx unknown
- 1997-02-22 EP EP00116745A patent/EP1069106B1/de not_active Expired - Lifetime
- 1997-02-22 AT AT00116745T patent/ATE258544T1/de active
- 1997-02-22 AT AT99119109T patent/ATE263140T1/de active
- 1997-02-22 DK DK00116745T patent/DK1069106T3/da active
- 1997-02-22 ES ES97102923T patent/ES2183030T3/es not_active Expired - Lifetime
- 1997-03-07 PE PE1997000175A patent/PE55798A1/es not_active Application Discontinuation
- 1997-03-07 BR BRPI9700369-7A patent/BR9700369B1/pt not_active IP Right Cessation
- 1997-03-11 KR KR1019970008046A patent/KR100538662B1/ko not_active IP Right Cessation
- 1997-03-11 AR ARP970100969A patent/AR008991A1/es active IP Right Grant
- 1997-03-11 CA CA002199679A patent/CA2199679C/en not_active Expired - Fee Related
- 1997-03-11 NZ NZ314384A patent/NZ314384A/xx unknown
- 1997-03-12 PL PL97318922A patent/PL186050B1/pl not_active IP Right Cessation
- 1997-03-12 US US08/820,377 patent/US5811582A/en not_active Expired - Lifetime
- 1997-03-12 RU RU97103580/04A patent/RU2167146C2/ru active
- 1997-03-12 IL IL12043097A patent/IL120430A/xx not_active IP Right Cessation
- 1997-03-12 HU HU9700574A patent/HU224819B1/hu not_active IP Right Cessation
- 1997-03-12 CN CNB971034877A patent/CN1157366C/zh not_active Expired - Fee Related
- 1997-03-12 NO NO971137A patent/NO308294B1/no not_active IP Right Cessation
- 1997-03-12 SK SK321-97A patent/SK284328B6/sk not_active IP Right Cessation
- 1997-03-12 CZ CZ1997759A patent/CZ293971B6/cs not_active IP Right Cessation
- 1997-03-12 UA UA97031138A patent/UA55373C2/uk unknown
- 1997-03-12 CO CO97013358A patent/CO4520279A1/es unknown
- 1997-03-12 AU AU16251/97A patent/AU725430B2/en not_active Ceased
- 1997-03-12 JP JP05769597A patent/JP4205182B2/ja not_active Expired - Fee Related
- 1997-03-12 ZA ZA9702147A patent/ZA972147B/xx unknown
2000
- 2000-08-24 HK HK00105323A patent/HK1026197A1/xx not_active IP Right Cessation
2001
- 2001-03-20 HK HK01101989A patent/HK1031864A1/xx not_active IP Right Cessation
2005
- 2005-06-03 KR KR1020050047916A patent/KR100602810B1/ko not_active IP Right Cessation
2008
- 2008-03-17 JP JP2008066934A patent/JP4846750B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP4846750B2 (ja)	2011-12-28
ZA972147B (en)	1997-09-17
EP1069106A2 (de)	2001-01-17
AU1625197A (en)	1997-09-18
EP0799819B1 (de)	2002-09-11
IL120430A (en)	2001-01-28
EP1069106B1 (de)	2004-01-28
CO4520279A1 (es)	1997-10-15
NZ314384A (en)	1999-06-29
EP0983994A3 (de)	2001-01-10
PE55798A1 (es)	1998-10-24
EP0983995B1 (de)	2004-03-31
SI0799819T1 (en)	2003-02-28
CZ293971B6 (cs)	2004-09-15
HUP9700574A3 (en)	2000-01-28
UA55373C2 (uk)	2003-04-15
SK284328B6 (sk)	2005-01-03
AR008991A1 (es)	2000-03-08
EP0983995A3 (de)	2001-01-10
IL120430A0 (en)	1997-07-13
EP0983995A2 (de)	2000-03-08
PL318922A1 (en)	1997-09-15
DE19609847A1 (de)	1997-09-18
HK1031864A1 (en)	2001-06-29
US5811582A (en)	1998-09-22
PL186050B1 (pl)	2003-09-30
CN1157366C (zh)	2004-07-14
NO971137L (no)	1997-09-15
SI1069106T1 (en)	2004-04-30
NO308294B1 (no)	2000-08-28
EP0983994A2 (de)	2000-03-08
JP2008273937A (ja)	2008-11-13
SI0983995T1 (en)	2004-10-31
DK0983995T3 (da)	2004-05-24
KR970065504A (ko)	1997-10-13
ATE258544T1 (de)	2004-02-15
DE59711477D1 (de)	2004-05-06
EP0799819A1 (de)	1997-10-08
MX9701865A (es)	1997-09-30
ES2213526T3 (es)	2004-09-01
KR100602810B1 (ko)	2006-07-20
HU9700574D0 (en)	1997-04-28
EP1069106A3 (de)	2001-01-24
DE59711267D1 (de)	2004-03-04
HK1026197A1 (en)	2000-12-08
CN1163884A (zh)	1997-11-05
SK32197A3 (en)	1997-12-10
HU224819B1 (en)	2006-02-28
ES2218924T3 (es)	2004-11-16
AU725430B2 (en)	2000-10-12
ATE263140T1 (de)	2004-04-15
JP4205182B2 (ja)	2009-01-07
CZ75997A3 (cs)	1998-04-15
DE59708160D1 (de)	2002-10-17
CA2199679A1 (en)	1997-09-13
NO971137D0 (no)	1997-03-12
DK1069106T3 (da)	2004-04-19
DK0799819T3 (da)	2002-12-02
JPH107624A (ja)	1998-01-13
BR9700369A (pt)	1998-10-27
PT983995E (pt)	2004-08-31
HUP9700574A2 (hu)	1998-10-28
ES2183030T3 (es)	2003-03-16
PT1069106E (pt)	2004-06-30
KR100538662B1 (ko)	2006-03-28
ATE223888T1 (de)	2002-09-15
CA2199679C (en)	2005-07-05
RU2167146C2 (ru)	2001-05-20
BR9700369B1 (pt)	2009-01-13

Publication	Publication Date	Title
PT946511E (pt)	2005-09-30	Novos compostos com efeito analgesico
PT946510E (pt)	2004-08-31	Novos compostos com efeito analgesico
PT799819E (pt)	2003-01-31	Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico
EE04640B1 (et)	2006-06-15	Valuvaigistava toimega ühendid
DE59602349D1 (de)	1999-08-05	Distanzschraube
ID19403A (id)	1998-07-09	Senyawa-senyawa heterosiklik
ID19609A (id)	1998-07-23	Senyawa-senyawa heterosiklik
ID16152A (id)	1997-09-04	Senyawa-senyawa triaril
DE69721624D1 (de)	2003-06-12	Einspritzdüse
ID15904A (id)	1997-08-14	Senyawa-senyawa tiofenopirimidina
BR9710352A (pt)	1999-08-17	Compostos piridilpirrole
PT979087E (pt)	2004-03-31	Combinacao de analgesicos
FI955783A (fi)	1996-06-02	Pyrrolijohdannaisia
DE69716924T2 (de)	2003-03-20	Phosphonat-nukleotid-verbindungen
BR9705635A (pt)	1999-05-18	Compostos
DK0923594T3 (da)	2003-02-10	Bromotiacumicinforbindelser
EE9800195A (et)	1998-12-15	Uudsed analgeetilise toimega ühendid
DE69709659T2 (de)	2002-09-12	Halopropargyl-einschlussverbindungen
DK1019042T3 (da)	2003-08-25	Forbindelser med anti-første-passagevirkning
DK0946511T3 (da)	2005-08-22	Hidtil ukendte forbindelser med analgesisk virkning
SI0946510T1 (en)	2004-12-31	Novel compounds with analgesic effect
SI0946511T1 (en)	2005-10-31	Novel compounds with analgesic effect
FI2962U1 (fi)	1997-06-27	Kaasusulku
ITBO960299A0 (it)	1996-06-04	Carburatore
KR970059190U (ko)	1997-11-10	기화기 써미스타