ID21681A - Peningkatan pada atau berkenaan dengan zat-zat kontras - Google Patents

Peningkatan pada atau berkenaan dengan zat-zat kontras

Info

Publication number
ID21681A
ID21681A IDW990382A ID990382A ID21681A ID 21681 A ID21681 A ID 21681A ID W990382 A IDW990382 A ID W990382A ID 990382 A ID990382 A ID 990382A ID 21681 A ID21681 A ID 21681A
Authority
ID
Indonesia
Prior art keywords
consequences
contrasting
substances
contrasting substances
Prior art date
Application number
IDW990382A
Other languages
English (en)
Inventor
Ostensen Jonny
Eriksen Morten
Frigstad Sigmund
Rongved Pal
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9621884.7A external-priority patent/GB9621884D0/en
Priority claimed from GBGB9708239.0A external-priority patent/GB9708239D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of ID21681A publication Critical patent/ID21681A/id

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927Diagnostic contrast agent
    • Y10S977/928X-ray agent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927Diagnostic contrast agent
    • Y10S977/929Ultrasound contrast agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IDW990382A 1996-10-21 1997-10-21 Peningkatan pada atau berkenaan dengan zat-zat kontras ID21681A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9621884.7A GB9621884D0 (en) 1996-10-21 1996-10-21 Improvements in or relating to contrast agents
GBGB9708239.0A GB9708239D0 (en) 1997-04-23 1997-04-23 Improvements in or relating to contrast agents

Publications (1)

Publication Number Publication Date
ID21681A true ID21681A (id) 1999-07-08

Family

ID=26310262

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990382A ID21681A (id) 1996-10-21 1997-10-21 Peningkatan pada atau berkenaan dengan zat-zat kontras

Country Status (26)

Country Link
US (3) US6375931B2 (id)
EP (2) EP1007100B1 (id)
JP (1) JP2001502349A (id)
KR (1) KR20000052652A (id)
CN (1) CN1106859C (id)
AP (1) AP885A (id)
AT (2) ATE381353T1 (id)
AU (1) AU745047B2 (id)
BG (1) BG103402A (id)
BR (1) BR9712370A (id)
CA (1) CA2269319C (id)
CZ (1) CZ140999A3 (id)
DE (2) DE69738406T2 (id)
EE (1) EE03749B1 (id)
ES (1) ES2197336T3 (id)
HU (1) HU224218B1 (id)
ID (1) ID21681A (id)
IL (1) IL129423A (id)
MX (1) MXPA99003664A (id)
NO (1) NO991869L (id)
NZ (1) NZ335265A (id)
PL (1) PL332820A1 (id)
RU (1) RU2204415C2 (id)
SK (1) SK283210B6 (id)
TR (1) TR199901544T2 (id)
WO (1) WO1998017324A2 (id)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
DE69724599T2 (de) * 1996-03-12 2004-08-05 The Board Of Regents Of The University Of Nebraska, Lincoln Zusammensetzung zur zielortspezifischen verabreichung eines medikamentes und verfahren zur anwendung
DE69718519T2 (de) * 1996-09-11 2003-11-06 Imarx Pharmaceutical Corp., Tucson Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
DE69738406T2 (de) * 1996-10-21 2008-12-04 Ge Healthcare As Verbesserungen in oder an Kontrastmitteln
GB9708246D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Improvements in or relating to ultrasound imaging
GB9717588D0 (en) 1997-08-19 1997-10-22 Nycomed Imaging As Improvements in or relating to contrast agents
EP1024837A1 (en) * 1997-10-21 2000-08-09 Nycomed Imaging As Ultrasound imaging with contrast agent targeted to microvasculature and a vasodilator drug
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19805012A1 (de) * 1998-02-07 1999-08-12 Thomas Gieselmann Kontrastmittel zur Verwendung als Diagnostikum bei bildgebenden Verfahren sowie seine Herstellung
GB9808599D0 (en) * 1998-04-22 1998-06-24 Nycomed Imaging As Improvements in or realting to contrast agents
GB9808581D0 (en) * 1998-04-22 1998-06-24 Nycomed Imaging As Improvements in or relating to contrast agents
US20040170564A1 (en) * 1998-04-22 2004-09-02 Roald Skurtveit Ultrasound contrast agent dispersions comprising gas and destabilising agent
GB9808582D0 (en) * 1998-04-22 1998-06-24 Nycomed Imaging As Improvements in or relating to contrast agents
GB9813568D0 (en) * 1998-06-23 1998-08-19 Nycomed Imaging As Improvements in or relating to cardiac imaging
US6984373B2 (en) 2000-12-23 2006-01-10 Dyax Corp. Fibrin binding moieties useful as imaging agents
NO20010234D0 (no) * 2001-01-12 2001-01-12 Nycomed Imaging As Perfusjon avbildningsbilde
US7179449B2 (en) * 2001-01-30 2007-02-20 Barnes-Jewish Hospital Enhanced ultrasound detection with temperature-dependent contrast agents
DE10115740A1 (de) * 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US20040166152A1 (en) * 2002-02-14 2004-08-26 Andreas Hirsch Use of buckysome or carbon nanotube for drug delivery
US20080193490A1 (en) * 2002-02-14 2008-08-14 Andreas Hirsch Use of Carbon Nanotube for Drug Delivery
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
EP1587944A4 (en) 2002-03-01 2007-03-21 Dyax Corp KDR AND VEGF / KDR BINDING PEPTIDES AND THEIR USE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
ES2506142T3 (es) 2002-03-01 2014-10-13 Dyax Corp. Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US20090060992A1 (en) * 2002-05-08 2009-03-05 University Of Central Florida Research Foundation, Inc., Preparation of magneto-vesicles with DOPE/DDAB layers
AU2003247376A1 (en) * 2002-05-17 2003-12-02 Case Western Reserve University Double contrast technique for mri-guided vascular interventions
WO2004026345A1 (en) * 2002-09-19 2004-04-01 New York University Control of nitric oxide bioactivity by perfluorocarbons
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
DK1593091T3 (da) * 2003-01-25 2013-10-28 Seno Medical Instr Inc Optoakustisk afbildning med høj kontrast ved anvendelse af ikke-sfæriske nanopartikler
US20040146461A1 (en) * 2003-01-29 2004-07-29 Vincenzo Giuliano Oral contrast media composition for computerized axial tomographic examinations and method
US7378081B2 (en) 2003-01-29 2008-05-27 Vincon Research Enterprises, Llc Composition and method for direct visualization of the human appendix
EP1604673B1 (en) * 2003-01-31 2007-08-29 Otsuka Pharmaceutical Factory, Inc. Auxiliary agent to be used in cancer therapy by dielectric heating and cancer therapy method
EP1590006B1 (en) * 2003-02-04 2010-09-08 Bracco Suisse SA Ultrasound contrast agents and process for the preparation thereof
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
ES2396368T3 (es) 2003-03-03 2013-02-21 Dyax Corporation Péptidos que se unen específicamente al receptor del HGF (CMET) y usos de los mismos
US20040258760A1 (en) * 2003-03-20 2004-12-23 Wheatley Margaret A. Isolated nanocapsule populations and surfactant-stabilized microcapsules and nanocapsules for diagnostic imaging and drug delivery and methods for their production
US20080299047A1 (en) * 2003-07-31 2008-12-04 National Cheng Kung University Method for preparation of water-soluble and dispersed iron oxide nanoparticles and application thereof
SE526838C2 (sv) * 2003-11-27 2005-11-08 Xcounter Ab Undersökningsmetod och anordning för detektion av joniserande strålning
ES2531732T3 (es) * 2003-12-22 2015-03-18 Bracco Suisse Sa Montaje de microvesícula rellena de gas para imagenología de contraste
CA2562606A1 (en) * 2004-04-13 2005-10-27 Cambridge Biostability Limited Liquids containing suspended glass particles
US8012457B2 (en) * 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
EP1784228B1 (en) * 2004-08-18 2016-10-05 Bracco Suisse SA Gas-filled microvesicles composition for contrast imaging
US8034222B2 (en) * 2004-10-26 2011-10-11 The Regents Of The University Of California Conducting polymer nanowire sensors
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
US20070167862A1 (en) * 2005-11-29 2007-07-19 Lopez George A Cardiac output measurement devices and methods
WO2007067979A2 (en) 2005-12-09 2007-06-14 Bracco International B.V. Targeting vector-phospholipid conjugates
ES2642570T3 (es) * 2006-02-28 2017-11-16 The Chemours Company Fc, Llc Composiciones azeotrópicas que comprenden compuestos fluorados para aplicaciones de limpieza
CN100400105C (zh) * 2006-05-11 2008-07-09 上海交通大学 水性基质的消化道ct阴性造影剂及其制备方法
JP4279328B2 (ja) * 2007-05-07 2009-06-17 株式会社日立製作所 超音波撮像システム
KR100957560B1 (ko) * 2007-10-18 2010-05-11 한국생명공학연구원 양자점 나노입자를 함유한 퍼플루오르카본 나노에멀젼 및그 제조방법
GB0811856D0 (en) * 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
US8908939B2 (en) * 2008-09-30 2014-12-09 Koninklijke Philips N.V. Perfusion imaging
US9072490B2 (en) * 2010-12-20 2015-07-07 Toshiba Medical Systems Corporation Image processing apparatus and image processing method
ITRM20110022A1 (it) * 2011-01-21 2012-07-22 Gaio Paradossi Metodo per la preparazione di microbolle comprendenti un agente di contrasto
RU2454174C2 (ru) * 2011-03-16 2012-06-27 Федеральное государственное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена" Министерства здравоохранения и социального развития Российской Федерации (ФГУ "МНИОИ им. П.А. Герцена" Минздравсоцразвития России) Способ диагностики опухолей шейки матки
RU2453270C1 (ru) * 2011-03-31 2012-06-20 Федеральное государственное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения и социального развития Российской Федерации" (ФГУ "МНИОИ им. П.А. Герцена" Минздравсоцразвития России) Способ исследования терминального отдела толстой кишки
RU2485976C2 (ru) * 2011-05-17 2013-06-27 Государственное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО СибГМУ Минздравсоцразвития России) Контрастное средство для ультразвуковой визуализации
RU2631800C2 (ru) * 2012-04-30 2017-09-26 ДжиИ Хелткер АС Способ заполнения контейнера вспениваемой композицией
BR112014032254B1 (pt) * 2012-06-26 2022-11-01 Ge Healthcare As Processo para a preparação de uma composição, aparelho, e, uso de um aparelho
CN103100093B (zh) * 2013-01-23 2015-05-06 中山大学附属第三医院 一种负载小干扰rna的纳米级脂质微泡超声造影剂及制备方法
WO2015047103A1 (en) 2013-09-27 2015-04-02 Phoenix Solutions As Ultrasound mediated delivery of drugs
EP3240579B1 (en) 2014-12-31 2022-07-27 Lantheus Medical Imaging, Inc. Lipid-encapsulated gas microsphere compositions and related methods
KR20180133527A (ko) 2016-05-04 2018-12-14 랜티우스 메디컬 이메징, 인크. 초음파 조영제의 제조 방법 및 장치
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
GB201821049D0 (en) * 2018-12-21 2019-02-06 Ge Healthcare As Ultrasound contrast agent and methods for use therof
US11642172B2 (en) * 2019-03-05 2023-05-09 Biosense Webster (Israel) Ltd. Showing catheter in brain
US12005130B2 (en) 2019-10-16 2024-06-11 Agitated Solutions Inc. Generating microbubbles for bubble studies
US11191888B1 (en) 2020-05-18 2021-12-07 Agitated Solutions Inc. Syringe-based microbubble generator
RU2744825C1 (ru) * 2020-06-03 2021-03-16 Федеральное государственное бюджетное образовательное учреждение высшего образования "Смоленский государственный медицинский университет" министерства здравоохранения Российской Федерации Способ определения времени течения артериальной фазы эхоконтрастирования печени, почек и селезенки

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5070877A (en) * 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
US5585112A (en) * 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5773024A (en) * 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5117830A (en) * 1990-11-08 1992-06-02 Whitby Research, Inc. Method of determining viability of tissue
CA2154590C (en) * 1993-01-25 2001-06-12 Steven C. Quay Phase shift colloids as ultrasound contrast agents
US5362478A (en) * 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
JP3559849B2 (ja) * 1993-07-30 2004-09-02 アイエムシーオーアール ファーマシューティカル カンパニー 超音波技術のための安定化された微小気泡組成物
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
DE4406474A1 (de) * 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
US5560364A (en) * 1995-05-12 1996-10-01 The Board Of Regents Of The University Of Nebraska Suspended ultra-sound induced microbubble cavitation imaging
US5804162A (en) * 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
DE69738406T2 (de) * 1996-10-21 2008-12-04 Ge Healthcare As Verbesserungen in oder an Kontrastmitteln
US6054118A (en) * 1997-01-22 2000-04-25 Nycomed Imaging As Contrast agents comprising two types of gas-containing microparticles

Also Published As

Publication number Publication date
DE69721331T2 (de) 2004-05-06
NO991869L (no) 1999-06-02
CN1238699A (zh) 1999-12-15
KR20000052652A (ko) 2000-08-25
EP1264604A2 (en) 2002-12-11
HUP0000282A3 (en) 2001-09-28
EP1007100B1 (en) 2003-04-23
EP1264604B1 (en) 2007-12-19
BR9712370A (pt) 1999-08-31
DE69721331D1 (de) 2003-05-28
JP2001502349A (ja) 2001-02-20
DE69738406D1 (de) 2008-01-31
IL129423A (en) 2003-01-12
AP9901511A0 (en) 1999-06-30
AP885A (en) 2000-11-03
RU2204415C2 (ru) 2003-05-20
EE9900158A (et) 1999-12-15
AU4714797A (en) 1998-05-15
US6375931B2 (en) 2002-04-23
US20010002993A1 (en) 2001-06-07
SK52099A3 (en) 2000-01-18
MXPA99003664A (es) 2002-06-11
US20040141921A1 (en) 2004-07-22
DE69738406T2 (de) 2008-12-04
NO991869D0 (no) 1999-04-19
AU745047B2 (en) 2002-03-07
ATE381353T1 (de) 2008-01-15
HU224218B1 (hu) 2005-06-28
SK283210B6 (sk) 2003-03-04
US20050118104A1 (en) 2005-06-02
US6783752B2 (en) 2004-08-31
NZ335265A (en) 2000-07-28
HUP0000282A2 (hu) 2000-05-28
EP1007100A2 (en) 2000-06-14
IL129423A0 (en) 2000-02-17
ES2197336T3 (es) 2004-01-01
EP1264604A3 (en) 2004-03-10
PL332820A1 (en) 1999-10-11
BG103402A (bg) 2000-01-31
CZ140999A3 (cs) 1999-09-15
CA2269319A1 (en) 1998-04-30
CN1106859C (zh) 2003-04-30
TR199901544T2 (xx) 1999-09-21
ATE238073T1 (de) 2003-05-15
WO1998017324A2 (en) 1998-04-30
EE03749B1 (et) 2002-06-17
WO1998017324A3 (en) 1998-06-25
CA2269319C (en) 2008-03-18

Similar Documents

Publication Publication Date Title
ID21681A (id) Peningkatan pada atau berkenaan dengan zat-zat kontras
NO984354D0 (no) Avisingsmiddel og anvendelse av dette
DE69828963D1 (de) Wirstoffabgabe und gentherapiesystem
EE04566B1 (et) Epotilooni derivaadid ja nende kasutamine meditsiinis
DE69704612D1 (de) Dentalmasse und dental-produkt
DE69709885D1 (de) Speichersystem und einrichtung
DE69738634D1 (de) Bildselektions- und anzeigegerät
DE69834616D1 (de) Tastsinnempfindlicher detektor und signalisierungseinheit
IS4481A (is) Díhýdrópyramídín og notkun þeirra
DE69911378D1 (de) Fluorierte ionomere und verwendung davon
PT946323E (pt) Pos de niobio e condensadores eletroliticos de niobio
DE69738197D1 (de) Azolotriazine und pyrimidine
NO983235D0 (no) Fikstur og protese innbefattende samme
BR9812128B8 (pt) Cateter iv e dispositivo de cateter
PT964849E (pt) Derivados de sulfonilureia e sua utilizacao no controlo da actovidade da interleucina-1
FI990466A0 (fi) Aktivaattorit ja laite
BR9702553A (pt) Composição cosmética e utilização
DK0898461T3 (da) Et system til måling og angivelse af ændringer i en levende krops modstand
DE69714613D1 (de) Magneto-Impedanz-Sensor
DK0906301T3 (da) Benzofurylderivater og anvendelsen deraf
DE69724772D1 (de) Flüssigkeitssensor
NO975439D0 (no) Ketonderivater og medisinsk anvendelse derav
DK0804078T3 (da) Sammensætning og anvendelse deraf
IS4898A (is) Sáraumbúðir
DE69724381D1 (de) Nichtreziproke Schaltungsanordnung