HUP9904616A2 - Meiózist befolyásoló holesztánszármazékok - Google Patents
Meiózist befolyásoló holesztánszármazékokInfo
- Publication number
- HUP9904616A2 HUP9904616A2 HU9904616A HUP9904616A HUP9904616A2 HU P9904616 A2 HUP9904616 A2 HU P9904616A2 HU 9904616 A HU9904616 A HU 9904616A HU P9904616 A HUP9904616 A HU P9904616A HU P9904616 A2 HUP9904616 A2 HU P9904616A2
- Authority
- HU
- Hungary
- Prior art keywords
- cholestane
- derivatives
- meiosis regulating
- meiosis
- regulating
- Prior art date
Links
- 230000021121 meiosis Effects 0.000 title abstract 2
- 150000001837 cholestane derivatives Chemical class 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- 244000309464 bull Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000001733 follicular fluid Anatomy 0.000 abstract 1
- 210000003794 male germ cell Anatomy 0.000 abstract 1
- 229930014626 natural product Natural products 0.000 abstract 1
- 210000000287 oocyte Anatomy 0.000 abstract 1
- 210000001550 testis Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- General Induction Heating (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
Bizőnyős (I) általánős képletű vegyületek, melyek szerkezetilegrőkőnők, példáűl a bikaheréből vagy hűmán tüszőnedvből extrahálhatótermészetes vegyületekkel, felhasználhatók őőciták és hímivarúcsírasejtek meiózisának befőlyásőlására. ŕ
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK147896 | 1996-12-20 | ||
US4148897P | 1997-02-11 | 1997-02-11 | |
PCT/DK1997/000584 WO1998028323A1 (en) | 1996-12-20 | 1997-12-19 | Meiosis regulating compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9904616A2 true HUP9904616A2 (hu) | 2000-06-28 |
HUP9904616A3 HUP9904616A3 (en) | 2001-02-28 |
Family
ID=26065809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9904616A HUP9904616A3 (en) | 1996-12-20 | 1997-12-19 | Meiosis regulating cholestane-derivatives |
Country Status (12)
Country | Link |
---|---|
US (3) | US6486145B2 (hu) |
EP (1) | EP0946584B1 (hu) |
JP (1) | JP2001506656A (hu) |
KR (1) | KR20000069616A (hu) |
AT (1) | ATE238339T1 (hu) |
AU (1) | AU746878B2 (hu) |
CA (1) | CA2275683A1 (hu) |
DE (1) | DE69721304T2 (hu) |
HU (1) | HUP9904616A3 (hu) |
IL (1) | IL130249A0 (hu) |
NO (1) | NO313144B1 (hu) |
WO (1) | WO1998028323A1 (hu) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030004148A1 (en) * | 1994-06-23 | 2003-01-02 | Byskov Anne G. | Regulation of meiosis |
EP1077992B1 (en) * | 1998-05-13 | 2003-12-10 | Novo Nordisk A/S | Use of meiosis regulating compounds |
IL139241A0 (en) * | 1998-05-13 | 2001-11-25 | Novo Nordisk As | Meiosis regulating compounds |
EP1087988A1 (en) * | 1998-06-19 | 2001-04-04 | Novo Nordisk A/S | Meiosis regulating compounds |
EP1137660B1 (en) | 1998-12-11 | 2002-10-02 | Akzo Nobel N.V. | 22s-hydroxycholesta-8,14-diene derivatives with meiosis regulating activity |
BR0008065A (pt) * | 1999-02-10 | 2001-11-06 | Schering Aktiengellschaft | Derivados de colestano insaturados e seu uso para a preparação de medicamentos que regulam meiose |
DE60034662T2 (de) * | 1999-02-24 | 2008-01-03 | Novo Nordisk A/S | Behandlung von unfruchtbarkeit |
HUP0200157A3 (en) * | 1999-02-24 | 2002-06-28 | Novo Nordisk As | Treatment of infertility |
ATE392899T1 (de) * | 1999-03-02 | 2008-05-15 | Organon Nv | (androst-5-en-17beta-yl)alkyl sulfoxide und sulfone und deren verwendung zur kontrolle der fruchtbarkeit |
DE60000978T2 (de) * | 1999-03-09 | 2003-07-17 | Akzo Nobel N.V., Arnheim/Arnhem | 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose |
US6902528B1 (en) * | 1999-04-14 | 2005-06-07 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling endoscopes in body lumens and cavities |
WO2001019354A2 (en) | 1999-09-16 | 2001-03-22 | Novo Nordisk A/S | Composition for ivf |
EP1127890A1 (en) | 2000-02-22 | 2001-08-29 | Schering Aktiengesellschaft | Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments |
WO2001062258A2 (en) * | 2000-02-25 | 2001-08-30 | Schering Aktiengesellschaft | Improvement of implantation rate using ff-mas |
WO2001076360A2 (en) * | 2000-04-06 | 2001-10-18 | Novo Nordisk A/S | Synchronization of the cytoplasmatic and the nuclear maturation of oocytes in vitro |
US6988613B2 (en) | 2001-02-06 | 2006-01-24 | Novo Nordisk A/S | Composition for IVF |
ATE386495T1 (de) * | 2001-02-06 | 2008-03-15 | Novo Nordisk As | Behältnis mit niedrigem sauerstoffgehalt, das ff- mas enthält |
EP1245572A1 (en) | 2001-03-26 | 2002-10-02 | Schering Aktiengesellschaft | Aminosterol compounds, their use in the preparation of meiosis-regulating medicaments and method for their preparation |
US8969543B2 (en) * | 2003-04-03 | 2015-03-03 | Bioneer Corporation | SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof |
US20080312673A1 (en) * | 2007-06-05 | 2008-12-18 | Viswanathan Raju R | Method and apparatus for CTO crossing |
WO2011127465A2 (en) | 2010-04-09 | 2011-10-13 | The Research Foundation Of The State University Of New York | Ship inhibitors and uses thereof |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1224738B (de) | 1960-12-29 | 1966-09-15 | Takeda Chemical Industries Ltd | Verfahren zur Herstellung von Cholestan-3, 5, 6-triol-3-estern oder -3, 6-diestern soowie von deren Salzen |
DE1183079B (de) | 1961-11-27 | 1964-12-10 | Vismara Francesco Spa | Verfahren zur Herstellung von gesaettigten 4-Hydroxy-3-keto-5alpha-steroiden |
CH470374A (de) | 1965-09-24 | 1969-03-31 | Hoffmann La Roche | Verfahren zur Herstellung von Steroiden |
DE1593492A1 (de) | 1966-01-29 | 1970-07-16 | Schering Ag | 6-Ketosteroide aus 20-Formyl-6-keto-Steroide |
IL38540A0 (en) | 1971-01-18 | 1972-03-28 | Dauten Sa | Method for the extraction of insect moulting steroid hormones |
ZA725157B (en) | 1971-07-29 | 1973-04-25 | Dauten Sa | New steroid of insecticide action and process for its production |
US4670190A (en) | 1973-01-10 | 1987-06-02 | Hesse Robert H | 1-α-hydroxy vitamin D compounds and process for preparing same |
FR2219943B1 (hu) | 1973-03-02 | 1976-04-30 | Eisai Co Ltd | |
IL41923A (en) | 1973-04-01 | 1978-08-31 | Yeda Res & Dev | Preparation of hydroxylated derivatives of cholestanol and some such compounds |
US3931403A (en) | 1973-05-25 | 1976-01-06 | Intellectual Property Development Corporation | Antimicrobial compositions |
US3887545A (en) | 1973-11-12 | 1975-06-03 | Hoffmann La Roche | Synthesis of 1{60 -hydroxylated cholesterol derivatives |
JPS5119752A (en) | 1974-08-07 | 1976-02-17 | Masayuki Ishikawa | 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho |
IL45897A (en) | 1974-10-22 | 1978-12-17 | Yeda Res & Dev | Process for the preparation of 1 hydroxy-provitamin d3 |
JPS6039278B2 (ja) | 1977-05-23 | 1985-09-05 | 中外製薬株式会社 | ステロイド誘導体 |
DE3064789D1 (en) | 1979-02-15 | 1983-10-20 | Teijin Ltd | New 25-hydroxy-24-oxocholestane derivatives and preparation thereof |
US4230626A (en) | 1979-07-30 | 1980-10-28 | G. D. Searle & Co. | 25-Halocholest-5-ene-3β,22-diols and esters thereof |
US4254045A (en) | 1980-04-21 | 1981-03-03 | Wisconsin Alumni Research Foundation | 1α-Hydroxy-2β-fluorocholecalciferol |
GB2089811B (en) | 1980-09-22 | 1984-09-26 | Wisconsin Alumni Res Found | 23,25-dihydroxyvitamin d3 |
ATE15050T1 (de) | 1981-04-29 | 1985-09-15 | Hoffmann La Roche | Verfahren zur herstellung von cholesterinderivaten und zwischenprodukte dafuer. |
US4329295A (en) | 1981-06-29 | 1982-05-11 | G. D. Searle & Co. | 24-Cyclopropylcholene-3β, 22-diols and esters thereof |
US4348328A (en) | 1981-11-09 | 1982-09-07 | G.D. Searle & Co. | 25-Substituted-5α-cholestane-3β,22S-diol |
US4871727A (en) | 1987-12-21 | 1989-10-03 | Merck & Co, Inc. | Anti-inflammatory and antidegenerative compounds isolated from L-681,512 |
JPH0749435B2 (ja) | 1988-07-04 | 1995-05-31 | 帝人株式会社 | 1α,3β,24−トリヒドロキシ−△▲上5▼−ステロイド類の製造方法 |
US5716777A (en) * | 1994-06-23 | 1998-02-10 | Novo Nordisk A/S | Regulation of meiosis using sterols |
HUP9800731A3 (en) * | 1995-03-06 | 2000-03-28 | Novo Nordisk As | Stimulation of meiosis |
-
1997
- 1997-12-19 CA CA002275683A patent/CA2275683A1/en not_active Abandoned
- 1997-12-19 HU HU9904616A patent/HUP9904616A3/hu unknown
- 1997-12-19 JP JP52826198A patent/JP2001506656A/ja not_active Ceased
- 1997-12-19 AT AT97948753T patent/ATE238339T1/de not_active IP Right Cessation
- 1997-12-19 DE DE69721304T patent/DE69721304T2/de not_active Expired - Fee Related
- 1997-12-19 EP EP97948753A patent/EP0946584B1/en not_active Expired - Lifetime
- 1997-12-19 IL IL13024997A patent/IL130249A0/xx unknown
- 1997-12-19 AU AU78789/98A patent/AU746878B2/en not_active Ceased
- 1997-12-19 KR KR1019997005616A patent/KR20000069616A/ko not_active Application Discontinuation
- 1997-12-19 WO PCT/DK1997/000584 patent/WO1998028323A1/en not_active Application Discontinuation
-
1999
- 1999-06-18 NO NO19993009A patent/NO313144B1/no unknown
-
2001
- 2001-01-17 US US09/764,203 patent/US6486145B2/en not_active Expired - Fee Related
-
2002
- 2002-09-11 US US10/242,381 patent/US6759400B2/en not_active Expired - Fee Related
-
2004
- 2004-05-11 US US10/843,488 patent/US20050004382A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0946584A1 (en) | 1999-10-06 |
AU7878998A (en) | 1998-07-17 |
CA2275683A1 (en) | 1998-07-02 |
KR20000069616A (ko) | 2000-11-25 |
IL130249A0 (en) | 2000-06-01 |
US20050004382A1 (en) | 2005-01-06 |
NO993009D0 (no) | 1999-06-18 |
US20030032824A1 (en) | 2003-02-13 |
NO313144B1 (no) | 2002-08-19 |
EP0946584B1 (en) | 2003-04-23 |
US6759400B2 (en) | 2004-07-06 |
WO1998028323A1 (en) | 1998-07-02 |
DE69721304T2 (de) | 2004-03-04 |
US6486145B2 (en) | 2002-11-26 |
DE69721304D1 (de) | 2003-05-28 |
ATE238339T1 (de) | 2003-05-15 |
AU746878B2 (en) | 2002-05-02 |
JP2001506656A (ja) | 2001-05-22 |
NO993009L (no) | 1999-08-19 |
HUP9904616A3 (en) | 2001-02-28 |
US20010005757A1 (en) | 2001-06-28 |
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