HUP9904201A1 - Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid, a non-viral and non-plasmid transfecting agent - Google Patents
Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid, a non-viral and non-plasmid transfecting agentInfo
- Publication number
- HUP9904201A1 HUP9904201A1 HU9904201A HUP9904201A HUP9904201A1 HU P9904201 A1 HUP9904201 A1 HU P9904201A1 HU 9904201 A HU9904201 A HU 9904201A HU P9904201 A HUP9904201 A HU P9904201A HU P9904201 A1 HUP9904201 A1 HU P9904201A1
- Authority
- HU
- Hungary
- Prior art keywords
- transfecting
- viral
- nucleic acid
- gene therapy
- exogenous nucleic
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 238000001415 gene therapy Methods 0.000 title abstract 2
- 239000013612 plasmid Substances 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/10—Vectors comprising a non-peptidic targeting moiety
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A találmány tárgya génterápiában alkalmazható transzfektálókészítmény, azzal jellemezve, hőgy egy vagy több, lipidtartalmúbűrőkkal nem rendelkező, és genőmjában legalább egy exőgénnűkleinsavat tartalmazó vírűs, és legalább egy nem virális és nemplazmid transzfektáló szer kőmbinációját tartalmazza. A találmányvőnatkőzik a készítmény segítségével előállítőtt rekőmbináns sejtre,valamint egy eljárására is nűkleinsavak sejtekbe történő átvitelére. ŕThe subject of the invention is a transfecting preparation that can be used in gene therapy, characterized by the fact that it contains a combination of one or more non-lipid-containing viruses and containing at least one exogenous nucleic acid in its genome, and at least one non-viral and non-plasmid transfecting agent. The invention is based on a recombinant cell produced with the help of the preparation, as well as a method for the transfer of nucleic acids into cells. ŕ
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9614693A FR2756491B1 (en) | 1996-11-29 | 1996-11-29 | TRANSFECTING COMPOSITION USEFUL IN GENE THERAPY ASSOCIATED WITH A RECOMBINANT VIRUS INCORPORATING EXOG ENE NUCLEIC ACID, A NON-VIRAL AND NON-PLASMIDIC TRANSFECTING AGENT |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9904201A1 true HUP9904201A1 (en) | 2000-04-28 |
HUP9904201A3 HUP9904201A3 (en) | 2002-01-28 |
Family
ID=9498192
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9904201A HUP9904201A3 (en) | 1996-11-29 | 1997-11-28 | Transfecting composition usable in gene therapy combining a recombinant virus incorporating an exogenous nucleic acid, a non-viral and non-plasmid transfecting agent |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0948636A1 (en) |
JP (1) | JP2001514485A (en) |
KR (1) | KR20000057307A (en) |
AU (1) | AU737846B2 (en) |
BR (1) | BR9713434A (en) |
CA (1) | CA2272637A1 (en) |
CZ (1) | CZ188299A3 (en) |
FR (1) | FR2756491B1 (en) |
HU (1) | HUP9904201A3 (en) |
IL (1) | IL130053A0 (en) |
NO (1) | NO992577L (en) |
SK (1) | SK70999A3 (en) |
WO (1) | WO1998023765A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100764890B1 (en) * | 2005-11-14 | 2007-10-09 | 한국화학연구원 | Anticancer agent using liposome by polyethylenimine conjugated with DSPE and preparation method |
WO2008097623A2 (en) | 2007-02-07 | 2008-08-14 | Gradalis, Inc. | Methods and compositions for modulating sialic acid production and treating hereditary inclusion body myopathy |
KR100980395B1 (en) | 2008-06-27 | 2010-09-07 | 재단법인서울대학교산학협력재단 | Polymer/DNA complex for non-viral DNA carrier |
JP5944622B2 (en) * | 2011-04-08 | 2016-07-05 | 株式会社ブリヂストン | Gene transfer agent composition |
US9598713B2 (en) | 2012-03-02 | 2017-03-21 | Japanese Science And Technology Agency | Method for constructing functional nucleic acid molecule, and nucleic acid combination to be used in said method |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2646161B1 (en) * | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | NEW LIPOPOLYAMINES, THEIR PREPARATION AND THEIR USE |
US5552309A (en) * | 1994-09-30 | 1996-09-03 | Indiana University Foundation | Use of polyols for improving the introduction of genetic material into cells |
FR2727679B1 (en) * | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | NEW TRANSFECTION AGENTS AND THEIR PHARMACEUTICAL APPLICATIONS |
FR2730637B1 (en) * | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | PHARMACEUTICAL COMPOSITION CONTAINING NUCLEIC ACIDS, AND USES THEREOF |
FR2741066B1 (en) * | 1995-11-14 | 1997-12-12 | Rhone Poulenc Rorer Sa | NEW TRANSFECTION AGENTS AND THEIR PHARMACEUTICAL APPLICATIONS |
-
1996
- 1996-11-29 FR FR9614693A patent/FR2756491B1/en not_active Expired - Fee Related
-
1997
- 1997-11-28 IL IL13005397A patent/IL130053A0/en unknown
- 1997-11-28 WO PCT/FR1997/002157 patent/WO1998023765A1/en not_active Application Discontinuation
- 1997-11-28 CA CA002272637A patent/CA2272637A1/en not_active Abandoned
- 1997-11-28 JP JP52437898A patent/JP2001514485A/en active Pending
- 1997-11-28 HU HU9904201A patent/HUP9904201A3/en unknown
- 1997-11-28 AU AU74010/98A patent/AU737846B2/en not_active Ceased
- 1997-11-28 CZ CZ991882A patent/CZ188299A3/en unknown
- 1997-11-28 KR KR1019990704738A patent/KR20000057307A/en not_active Application Discontinuation
- 1997-11-28 EP EP97948959A patent/EP0948636A1/en not_active Withdrawn
- 1997-11-28 SK SK709-99A patent/SK70999A3/en unknown
- 1997-11-28 BR BR9713434-1A patent/BR9713434A/en not_active IP Right Cessation
-
1999
- 1999-05-28 NO NO992577A patent/NO992577L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
SK70999A3 (en) | 2000-03-13 |
BR9713434A (en) | 2000-02-01 |
IL130053A0 (en) | 2000-02-29 |
NO992577D0 (en) | 1999-05-28 |
KR20000057307A (en) | 2000-09-15 |
HUP9904201A3 (en) | 2002-01-28 |
CA2272637A1 (en) | 1998-06-04 |
AU7401098A (en) | 1998-06-22 |
AU737846B2 (en) | 2001-08-30 |
EP0948636A1 (en) | 1999-10-13 |
WO1998023765A1 (en) | 1998-06-04 |
CZ188299A3 (en) | 1999-09-15 |
JP2001514485A (en) | 2001-09-11 |
FR2756491A1 (en) | 1998-06-05 |
NO992577L (en) | 1999-07-28 |
FR2756491B1 (en) | 1999-01-08 |
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