HUP9901109A2 - Immunogén peptidek vakcinálásra és allergia kezelésére - Google Patents

Immunogén peptidek vakcinálásra és allergia kezelésére

Info

Publication number
HUP9901109A2
HUP9901109A2 HU9901109A HUP9901109A HUP9901109A2 HU P9901109 A2 HUP9901109 A2 HU P9901109A2 HU 9901109 A HU9901109 A HU 9901109A HU P9901109 A HUP9901109 A HU P9901109A HU P9901109 A2 HUP9901109 A2 HU P9901109A2
Authority
HU
Hungary
Prior art keywords
allergy
treatment
peptide
ige
vaccination against
Prior art date
Application number
HU9901109A
Other languages
English (en)
Inventor
Franz Kricek
Beda Stadler
Original Assignee
Novartis Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26308839&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9901109(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9604412.8A external-priority patent/GB9604412D0/en
Priority claimed from GBGB9617702.7A external-priority patent/GB9617702D0/en
Application filed by Novartis Ag. filed Critical Novartis Ag.
Publication of HUP9901109A2 publication Critical patent/HUP9901109A2/hu
Publication of HUP9901109A3 publication Critical patent/HUP9901109A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/528CH4 domain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A találmány őlyan imműnőgén mőlekűlákra vőnatkőzik, melyek (a) a BSW17mőnőklőnális anti-hűmán IgE antitest által felismert, hűmán IgE-n lévőtermészetes epitópőt űtánőzó peptid legalább egy részét és (b) apeptiddel szembeni imműnválasz kiváltására képes részt tartalmaznak.Ezek a mőlekűlák gyógyszerkészítményekben vagy gyógyszerkészítményekelőállítására használhatók, különösen IgE-közvetített betegségek, mintpéldáűl allergia és atópiás dermatitisz kezelésére szőlgálógyógyszerkészítményekben, példáűl allergiaellenes vakcinákban. ŕ
HU9901109A 1996-03-01 1997-02-28 Peptide immunogens for vaccination against and treatment of allergy HUP9901109A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9604412.8A GB9604412D0 (en) 1996-03-01 1996-03-01 Organic compounds
GBGB9617702.7A GB9617702D0 (en) 1996-08-22 1996-08-22 Organic compounds

Publications (2)

Publication Number Publication Date
HUP9901109A2 true HUP9901109A2 (hu) 1999-07-28
HUP9901109A3 HUP9901109A3 (en) 1999-11-29

Family

ID=26308839

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901109A HUP9901109A3 (en) 1996-03-01 1997-02-28 Peptide immunogens for vaccination against and treatment of allergy

Country Status (25)

Country Link
US (1) US6610297B1 (hu)
EP (1) EP0885244B2 (hu)
JP (2) JP3421970B2 (hu)
KR (2) KR100584051B1 (hu)
CN (1) CN1174998C (hu)
AT (1) ATE230417T1 (hu)
AU (1) AU719609B2 (hu)
BR (1) BR9707819A (hu)
CA (1) CA2245497C (hu)
CY (1) CY2457B1 (hu)
CZ (1) CZ299551B6 (hu)
DE (1) DE69718150T3 (hu)
DK (1) DK0885244T4 (hu)
ES (1) ES2190799T5 (hu)
HK (1) HK1014962A1 (hu)
HU (1) HUP9901109A3 (hu)
IL (1) IL125590A (hu)
NO (1) NO321043B1 (hu)
NZ (1) NZ331651A (hu)
PL (1) PL187209B1 (hu)
RU (1) RU2193413C2 (hu)
SI (1) SI0885244T2 (hu)
SK (1) SK284856B6 (hu)
TR (1) TR199801722T2 (hu)
WO (1) WO1997031948A1 (hu)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913749B2 (en) 1998-11-02 2005-07-05 Resistentia Pharmaceuticals Ab Immunogenic polypeptides for inducing anti-self IgE responses
EP1621209A3 (en) * 1998-11-02 2006-04-19 Resistentia Pharmaceuticals AB Vaccines based on domains of chimeric immunoglobulin E peptides
BR9915771A (pt) 1998-11-30 2001-12-26 Cytos Biotechnology Ag Apresentação molecular ordenada de antìgenos,processo de preparação e utilização
AU3158900A (en) * 1999-02-25 2000-09-14 Smithkline Beecham Biologicals (Sa) Immunogens comprising a peptide and a carrier derived from h.influenzae protein
CN1520423A (zh) * 1999-02-25 2004-08-11 ʷ��˿�������ȳ�ķ���޹�˾ 来源于IgE的Cε3或Cε4区的抗原决定基或拟表位,其拮抗物,及其治疗用途
GB9908533D0 (en) * 1999-04-14 1999-06-09 Novartis Ag Organic compounds
CA2405290C (en) * 2000-04-13 2011-06-21 Bio Life Science Forschungs Und Entwicklungsgesellschaft Mbh Vaccine against cancerous diseases
WO2001085208A2 (en) 2000-05-05 2001-11-15 Cytos Biotechnology Ag Molecular antigen arrays and vaccines
EP2361635A3 (en) 2000-08-30 2011-09-14 Pfizer Products Inc. Anti IgE vaccines
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7264810B2 (en) 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
ES2394293T3 (es) * 2001-02-28 2013-01-30 Bio Life Science Forschungs- Und Entwicklungsges.M.B.H. Vacuna contra cánceres que están asociados con el oncogén HER-2/neu
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
JP2003047482A (ja) 2001-05-22 2003-02-18 Pfizer Prod Inc 非アナフィラキシー誘発性IgEワクチン
WO2003015716A2 (en) 2001-08-13 2003-02-27 Ige Therapeutics, Inc. Immunoglobulin e vaccines and methods of use thereof
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
US20050226894A1 (en) * 2002-01-15 2005-10-13 Jensen-Jarolim Erika Oral vaccination
CN1668637B (zh) 2002-07-17 2010-05-26 希托斯生物技术股份公司 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列
US6932971B2 (en) 2002-07-18 2005-08-23 Cytos Biotechnology Ag Hapten-carrier conjugates and uses thereof
BR0312792A (pt) 2002-07-19 2005-05-03 Cytos Biotechnology Ag Composições de vacinas contendo séries antigênicas de amilóide beta1-6
US7425620B2 (en) 2002-08-14 2008-09-16 Scott Koenig FcγRIIB-specific antibodies and methods of use thereof
US20050065136A1 (en) * 2003-08-13 2005-03-24 Roby Russell R. Methods and compositions for the treatment of infertility using dilute hormone solutions
US20050239757A1 (en) * 2004-04-21 2005-10-27 Roby Russell R Hormone treatment of macular degeneration
US20060025390A1 (en) * 2004-07-28 2006-02-02 Roby Russell R Treatment of hormone allergy and related symptoms and disorders
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
EP2029173B1 (en) 2006-06-26 2016-07-20 MacroGenics, Inc. Fc riib-specific antibodies and methods of use thereof
EP2012122A1 (en) * 2007-07-06 2009-01-07 Medigene AG Mutated parvovirus structural proteins as vaccines
US8865179B2 (en) * 2008-01-26 2014-10-21 Swey-Shen Alexchen Aptameric IgE peptides in a protein scaffold as an allergy vaccine
KR101634058B1 (ko) 2008-12-09 2016-06-27 화이자 백신스 엘엘씨 IgE CH3 펩티드 백신
WO2011154878A1 (en) * 2010-06-07 2011-12-15 Pfizer Vaccines Llc Ige ch3 peptide vaccine
RU2761431C9 (ru) * 2020-10-26 2022-04-18 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Рекомбинантный полипептид на основе аллергена пыльцы березы и аллергена яблока в качестве вакцины от аллергии

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2602443A1 (de) 1975-04-04 1976-10-21 Univ California Biologisch aktive polypeptide
US4171299A (en) 1975-04-04 1979-10-16 The Regents Of The University Of California Polypeptide agents for blocking the human allergic response
DE2861593D1 (en) 1977-06-29 1982-03-11 Beecham Group Plc Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides
JPS5944399A (ja) 1982-09-07 1984-03-12 Takeda Chem Ind Ltd 新規dna
GB8616166D0 (en) * 1986-07-02 1986-08-06 Research Corp Ltd Polypeptide competitor
US4892827A (en) 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
EP0269455A3 (en) 1986-11-28 1989-09-06 Takeda Chemical Industries, Ltd. Highly purified fused protein comprising human ige fc fragment and production thereof
EP0344211A4 (en) 1987-02-20 1990-03-12 Imclone Systems Inc MONOCLONAL ANTIBODIES IN VACCINE COMPOSITIONS.
CA1336818C (en) 1987-04-16 1995-08-29 International Institute Of Cellular And Molecular Pathology Treatment of allergy and composition thereof
WO1989003430A1 (en) 1987-10-13 1989-04-20 Terrapin Diagnostics, Ltd. Method to produce immunodiagnostic reagents
GB8727045D0 (en) 1987-11-19 1987-12-23 Research Corp Ltd Immunoglobulin e competitor
US5449760A (en) 1987-12-31 1995-09-12 Tanox Biosystems, Inc. Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils
US5342924A (en) 1987-12-31 1994-08-30 Tanox Biosystems, Inc. Extracellular segments of human ε immunoglobulin anchoring peptides and antibodies specific therefor
GB8910263D0 (en) 1989-05-04 1989-06-21 Ciba Geigy Ag Monoclonal antibodies specific for an immunoglobulin isotype
GB8913737D0 (en) 1989-06-15 1989-08-02 Univ Birmingham A novel anti-allergy treatment
CA2074089C (en) 1990-01-23 2001-04-10 Tse-Wen Chang Extracellular segments of human e immunoglobulin anchoring peptides and antibodies specific therefor
WO1991019001A1 (en) 1990-05-25 1991-12-12 British Technology Group Ltd Immunodiagnostic assay for rheumatoid arthritis
US5258289A (en) 1990-09-05 1993-11-02 Davis Claude G Method for the selecting of genes encoding catalytic antibodies
GB9101550D0 (en) 1991-01-24 1991-03-06 Mastico Robert A Antigen-presenting chimaeric protein
ATE233813T1 (de) * 1991-08-14 2003-03-15 Genentech Inc Veränderte immunglobuline für spezifische fc- epsilon rezeptoren
US5965709A (en) * 1991-08-14 1999-10-12 Genentech, Inc. IgE antagonists
SE9102808L (sv) * 1991-09-26 1993-03-27 Lars T Hellman Inst F Immunolo Vaccin, foer humant bruk, vars avsedda effekt aer att lindra symptomen eller foerhindra uppkomsten av ige-medierade allergiska reaktioner
GB9125024D0 (en) 1991-11-25 1992-01-22 Kirby Julian Rheumatoid arthritus treatment
JPH06113881A (ja) 1992-10-07 1994-04-26 Snow Brand Milk Prod Co Ltd ヒト型モノクローナル抗ペプチド抗体及びこれをコードするdna
JP3795914B2 (ja) 1993-04-27 2006-07-12 ユナイテッド・バイオメディカル・インコーポレイテッド ワクチン用免疫原性lhrhペプチド構築体および合成普遍免疫刺激器
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
CA2160786A1 (en) 1993-05-14 1994-11-24 James C. Marsters, Jr. Ras farnesyl transferase inhibitors
GB9320897D0 (en) 1993-10-11 1993-12-01 Peptide Therapeutics Ltd Compounds useful in anti-allergy treatment
GB9324013D0 (en) * 1993-11-22 1994-01-12 3I Res Expl Ltd Polypeptides
FR2715304B1 (fr) * 1994-01-26 1996-04-26 Merieux Serums Vaccins Pasteur Vaccin anti-allergique.
AU2195395A (en) 1994-03-28 1995-10-17 United Biomedical Inc. Synthetic peptide based immunogens for the treatment of allergy
US5962634A (en) 1994-07-08 1999-10-05 Thomas Jefferson University IgE antagonists
CA2203165A1 (en) 1994-10-25 1996-05-02 United Biomedical, Inc. Synthetic ige membrane anchor peptide immunogens for the treatment of allergy
AU6532498A (en) 1996-12-06 1998-06-29 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Inhibition of ige-mediated allergies by a human ige-derived oligopeptide
EP0955311A3 (en) 1998-04-09 2000-08-16 Idexx Laboratories, Inc. Peptide vaccine for canine allergy
TWI229679B (en) 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens

Also Published As

Publication number Publication date
KR100498198B1 (ko) 2005-09-09
SK284856B6 (sk) 2006-01-05
US6610297B1 (en) 2003-08-26
DK0885244T3 (da) 2003-04-22
JP2000502571A (ja) 2000-03-07
CY2457B1 (en) 2005-06-03
KR100584051B1 (ko) 2006-05-30
CZ299551B6 (cs) 2008-08-27
BR9707819A (pt) 1999-07-27
IL125590A0 (en) 1999-03-12
ES2190799T3 (es) 2003-08-16
ATE230417T1 (de) 2003-01-15
ES2190799T5 (es) 2008-08-16
AU719609B2 (en) 2000-05-11
JP2003231696A (ja) 2003-08-19
HK1014962A1 (en) 1999-10-08
PL328858A1 (en) 1999-03-01
EP0885244B2 (en) 2008-04-16
IL125590A (en) 2001-08-26
CZ277198A3 (cs) 1998-12-16
HUP9901109A3 (en) 1999-11-29
NO983999D0 (no) 1998-08-31
AU1879697A (en) 1997-09-16
CN1174998C (zh) 2004-11-10
NO321043B1 (no) 2006-03-06
SI0885244T2 (sl) 2008-10-31
SI0885244T1 (en) 2003-06-30
DE69718150T2 (de) 2003-08-21
KR20050049509A (ko) 2005-05-25
CA2245497C (en) 2009-02-24
DK0885244T4 (da) 2008-06-16
KR19990087425A (ko) 1999-12-27
CA2245497A1 (en) 1997-09-04
DE69718150D1 (de) 2003-02-06
WO1997031948A1 (en) 1997-09-04
PL187209B1 (pl) 2004-06-30
EP0885244B1 (en) 2003-01-02
NO983999L (no) 1998-11-02
DE69718150T3 (de) 2009-03-05
EP0885244A1 (en) 1998-12-23
SK118198A3 (en) 1999-03-12
CN1213380A (zh) 1999-04-07
NZ331651A (en) 2000-01-28
RU2193413C2 (ru) 2002-11-27
TR199801722T2 (xx) 1998-12-21
JP3421970B2 (ja) 2003-06-30

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Legal Events

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