HUP9900050A1 - Rekombináns adenovírusok, és felhasználásuk adeno-asszociált vírusok (AAV) előállítására, komplementáló sejtvonalak, és az illető adenovírusokat tartalmazó gyógyszerkészítmények - Google Patents

Rekombináns adenovírusok, és felhasználásuk adeno-asszociált vírusok (AAV) előállítására, komplementáló sejtvonalak, és az illető adenovírusokat tartalmazó gyógyszerkészítmények

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Publication number
HUP9900050A1
HUP9900050A1 HU9900050A HUP9900050A HUP9900050A1 HU P9900050 A1 HUP9900050 A1 HU P9900050A1 HU 9900050 A HU9900050 A HU 9900050A HU P9900050 A HUP9900050 A HU P9900050A HU P9900050 A1 HUP9900050 A1 HU P9900050A1
Authority
HU
Hungary
Prior art keywords
adenoviruses
aavs
cell line
preparing
pharmaceutical compositions
Prior art date
Application number
HU9900050A
Other languages
English (en)
Inventor
Martine Latta
Cécile Orsini
Michel Perricaudet
Edouard Prost
Emmanuelle Vigne
Patrice Yeh
Original Assignee
Rhone-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone-Poulenc Rorer S.A. filed Critical Rhone-Poulenc Rorer S.A.
Publication of HUP9900050A1 publication Critical patent/HUP9900050A1/hu
Publication of HUP9900050A3 publication Critical patent/HUP9900050A3/hu
Publication of HU224679B1 publication Critical patent/HU224679B1/hu

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10344—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination

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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A találmány tárgya egy rekőmbináns adenővírűs, amelyben legalább egyvirális eredetű, hőmőlóg vagy heterőlóg gént kódőló nűkleinsavszekvencia expressziója egy indűkálható prőmóter szabályőzása alattáll. A találmány vőnatkőzik még ezen rekőmbináns adenővírűsők alkalmazásáraAAV-k előállítására, egy kőmplementáló sejtvőnalra, és a megfelelőelőállítási eljárásra. A találmány körébe tartőznak még a találmányszerinti adenővírűst tartalmazó gyógyszerkészítmények is. ŕ
HU9900050A 1995-06-23 1996-06-20 Rekombináns adenovírusok és felhasználásuk adeno-asszociált vírusok (AAV) előállítására, komplementáló sejtvonalak és a rekombináns adenovírusokat tartalmazó gyógyszerkészítmények HU224679B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9507570A FR2735789B1 (fr) 1995-06-23 1995-06-23 Adenovirus recombinants, leur utilisation pour preparer des aav, lignee cellulaire complementaire et compositions pharmaceutiques les contenant
PCT/FR1996/000968 WO1997000947A1 (fr) 1995-06-23 1996-06-20 Adenovirus recombinants, leur utilisation pour preparer des aav, lignee cellulaire complementaire et compositions pharmaceutiques les contenant

Publications (3)

Publication Number Publication Date
HUP9900050A1 true HUP9900050A1 (hu) 1999-04-28
HUP9900050A3 HUP9900050A3 (en) 2001-08-28
HU224679B1 HU224679B1 (hu) 2005-12-28

Family

ID=9480335

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900050A HU224679B1 (hu) 1995-06-23 1996-06-20 Rekombináns adenovírusok és felhasználásuk adeno-asszociált vírusok (AAV) előállítására, komplementáló sejtvonalak és a rekombináns adenovírusokat tartalmazó gyógyszerkészítmények

Country Status (16)

Country Link
US (3) US6420170B1 (hu)
EP (1) EP0833896A1 (hu)
JP (1) JP3821846B2 (hu)
KR (1) KR100514070B1 (hu)
AU (1) AU716508B2 (hu)
BR (1) BR9608965A (hu)
CA (1) CA2222270A1 (hu)
CZ (1) CZ295934B6 (hu)
FR (1) FR2735789B1 (hu)
HU (1) HU224679B1 (hu)
IL (2) IL122710A (hu)
MX (1) MX9709549A (hu)
NO (1) NO975953D0 (hu)
SK (1) SK174297A3 (hu)
WO (1) WO1997000947A1 (hu)
ZA (1) ZA965306B (hu)

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Publication number Publication date
CZ413097A3 (cs) 1998-03-18
FR2735789A1 (fr) 1996-12-27
SK174297A3 (en) 1998-09-09
AU716508B2 (en) 2000-02-24
BR9608965A (pt) 1999-06-29
CZ295934B6 (cs) 2005-12-14
KR100514070B1 (ko) 2005-12-21
ZA965306B (en) 1997-01-24
HUP9900050A3 (en) 2001-08-28
US20030039634A1 (en) 2003-02-27
CA2222270A1 (fr) 1997-01-09
KR19990028307A (ko) 1999-04-15
NO975953L (no) 1997-12-18
WO1997000947A1 (fr) 1997-01-09
FR2735789B1 (fr) 1997-07-25
JPH11507835A (ja) 1999-07-13
AU6363996A (en) 1997-01-22
IL122710A0 (en) 1998-08-16
NO975953D0 (no) 1997-12-18
US20020098165A1 (en) 2002-07-25
HU224679B1 (hu) 2005-12-28
US7033826B2 (en) 2006-04-25
JP3821846B2 (ja) 2006-09-13
IL122710A (en) 2006-10-05
EP0833896A1 (fr) 1998-04-08
MX9709549A (es) 1998-03-31
US6420170B1 (en) 2002-07-16

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