HUP9800198A2 - The use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]-butyl}-1h-azole derivatives for producing medicaments - Google Patents

The use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]-butyl}-1h-azole derivatives for producing medicaments

Info

Publication number
HUP9800198A2
HUP9800198A2 HU9800198A HUP9800198A HUP9800198A2 HU P9800198 A2 HUP9800198 A2 HU P9800198A2 HU 9800198 A HU9800198 A HU 9800198A HU P9800198 A HUP9800198 A HU P9800198A HU P9800198 A2 HUP9800198 A2 HU P9800198A2
Authority
HU
Hungary
Prior art keywords
piperazinyl
heteroaryl
aryl
butyl
azole derivatives
Prior art date
Application number
HU9800198A
Other languages
Hungarian (hu)
Inventor
Jordi Frigola-Constansa
Original Assignee
Laboratorios Del Dr. Esteve S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Del Dr. Esteve S.A. filed Critical Laboratorios Del Dr. Esteve S.A.
Publication of HUP9800198A2 publication Critical patent/HUP9800198A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A találmány tárgya 1-{4-[4-aril- (vagy -heterőaril)-1-piperazinil]-bűtil}-1H-azől-származékők, valamint ezek fiziőlógiásan elfőgadhatósóinak alkalmazása őlyan gyógyszerkészítmények előállítására, amelyekkényszerképzet jellegű rendellenességek, alvás közbeni légzéselakadástünete, szexűális diszfűnkciók, hányás és útibetegség kezelésérealkalmazhatók emlősök esetén, beleértve az embert. ŕThe subject of the invention is the use of 1-{4-[4-aryl- (or -heteroaryl)-1-piperazinyl]-butyl}-1H-azol derivatives and their physiologically soluble salts for the production of pharmaceutical preparations that treat compulsive-like disorders, sleep apnea, can be used to treat sexual dysfunctions, vomiting and motion sickness in mammals, including humans. ŕ

HU9800198A 1995-12-12 1996-12-11 The use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]-butyl}-1h-azole derivatives for producing medicaments HUP9800198A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514690A FR2742052B1 (en) 1995-12-12 1995-12-12 USE OF DERIVATIVES 1- (4- (4-ARYL (OR HETEROARYL) -1-PIPER AZINYL) -BUTY) -1H-AZOLE FOR THE TREATMENT OF DEPRESSION, OBSESSIVE COMPULSIVE DISORDERS, SLEEP APNEA, SEXUAL DYSFUNCTIONS , Emese and motion sickness

Publications (1)

Publication Number Publication Date
HUP9800198A2 true HUP9800198A2 (en) 1999-09-28

Family

ID=9485400

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800198A HUP9800198A2 (en) 1995-12-12 1996-12-11 The use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]-butyl}-1h-azole derivatives for producing medicaments

Country Status (16)

Country Link
EP (1) EP0808166A1 (en)
JP (1) JPH11501051A (en)
CN (1) CN1177297A (en)
AR (1) AR004378A1 (en)
AU (1) AU716665B2 (en)
CA (1) CA2211161A1 (en)
CZ (1) CZ255197A3 (en)
ES (1) ES2134709B1 (en)
FR (1) FR2742052B1 (en)
HU (1) HUP9800198A2 (en)
IL (1) IL121461A0 (en)
NO (1) NO973589L (en)
PL (1) PL321779A1 (en)
TR (1) TR199700794T1 (en)
WO (1) WO1997021439A1 (en)
ZA (1) ZA9610457B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763950B1 (en) * 1997-06-02 2002-09-20 Esteve Labor Dr 2- {4- [4- (4,5-DICHLORO-2-METHYLIMIDAZOL-1-YL) BUTYL] -1- PIPERAZINYL} -5-FLUOROPYRIMIDINE, ITS PREPARATION AND THERAPEUTIC USE
TW526202B (en) * 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US6046331A (en) * 1998-12-17 2000-04-04 Synaptic Pharmaceutical Corporation Imidazolones and their use in treating benign prostatic hyperplasia and other disorders
JP5140225B2 (en) 2000-08-14 2013-02-06 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド Substituted pyrazoles
JP5049447B2 (en) 2000-08-14 2012-10-17 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド Substituted pyrazoles
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
WO2002014317A2 (en) 2000-08-14 2002-02-21 Ortho Mcneil Pharmaceutical, Inc. Substituted pyrazoles
MXPA03001960A (en) 2000-09-06 2004-03-18 Johnson & Johnson A method for treating allergies.
CA2580730C (en) 2003-09-25 2015-01-13 Cenomed, Inc. Tetrahydroindolone derivatives for treatment of neurological conditions
WO2005094827A1 (en) * 2004-03-30 2005-10-13 Kestrel Pharmaceuticals Inc. Methods for treating sexual dysfunction
WO2006116615A1 (en) 2005-04-26 2006-11-02 Hypnion, Inc. Benzisoxazole piperazine compounds and methods of use thereof
ATE461925T1 (en) 2005-04-26 2010-04-15 Hypnion Inc BENZISOXAZOLEPIPERIDINE COMPOUNDS AND METHOD FOR USE THEREOF
GB2435827A (en) * 2006-03-09 2007-09-12 Del Dr Esteve S A Spain Lab Use of substituted piperazine compounds for the treatment of food related disorders
CN115304590A (en) * 2022-09-19 2022-11-08 皮摩尔新药(辽宁)有限公司 2H-benzotriazole derivatives, preparation method thereof and pharmaceutical composition containing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672052B1 (en) * 1991-01-28 1995-05-24 Esteve Labor Dr DERIVATIVES OF ARYL (OR HETEROARYL) -PIPERAZINYL-ALKYL-AZOLES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS.
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES

Also Published As

Publication number Publication date
AR004378A1 (en) 1998-11-04
ES2134709B1 (en) 2000-05-16
CZ255197A3 (en) 1998-01-14
EP0808166A1 (en) 1997-11-26
AU1376497A (en) 1997-07-03
IL121461A0 (en) 1998-02-08
MX9706133A (en) 1997-11-29
FR2742052B1 (en) 1998-04-10
AU716665B2 (en) 2000-03-02
NO973589D0 (en) 1997-08-04
CA2211161A1 (en) 1997-06-19
ZA9610457B (en) 1997-06-24
PL321779A1 (en) 1997-12-22
WO1997021439A1 (en) 1997-06-19
JPH11501051A (en) 1999-01-26
FR2742052A1 (en) 1997-06-13
CN1177297A (en) 1998-03-25
NO973589L (en) 1997-10-08
ES2134709A1 (en) 1999-10-01
TR199700794T1 (en) 1997-11-21

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