TR199700794T1 - 1-(4-(4-Aryl (or heteroaryl)-1-piperazinyl butyl)-1H-azole derivatives, compulsive obsessive disorders, sleep apnea syndrome, sexual It is used in the preparation of a drug to be used in the treatment of dysfunction, vomiting and motion sickness. - Google Patents

1-(4-(4-Aryl (or heteroaryl)-1-piperazinyl butyl)-1H-azole derivatives, compulsive obsessive disorders, sleep apnea syndrome, sexual It is used in the preparation of a drug to be used in the treatment of dysfunction, vomiting and motion sickness.

Info

Publication number
TR199700794T1
TR199700794T1 TR97/00794T TR9700794T TR199700794T1 TR 199700794 T1 TR199700794 T1 TR 199700794T1 TR 97/00794 T TR97/00794 T TR 97/00794T TR 9700794 T TR9700794 T TR 9700794T TR 199700794 T1 TR199700794 T1 TR 199700794T1
Authority
TR
Turkey
Prior art keywords
vomiting
heteroaryl
aryl
treatment
sleep apnea
Prior art date
Application number
TR97/00794T
Other languages
Turkish (tr)
Inventor
Frigola-Constansa Jord�
Original Assignee
Laboratorios Del Dr.Esteve, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Del Dr.Esteve, S.A. filed Critical Laboratorios Del Dr.Esteve, S.A.
Publication of TR199700794T1 publication Critical patent/TR199700794T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Bulus, 1-{4-[4-aril (veya heteroaril)-1-piperazinil]bütil} -1 H-azol türevlerinin ve bunlarin fizyolojik olarak kabul edilebilir tuzlarinin, kompulsif obsesif bozukluklar, uykuda apne sendromu, cinsel fonksiyon bozukluklan, kusma ve tasit tutmasinin tedavisinde kullanilacak olan ilaçlarin imalati için kullanilmasina iliskindir.Invention, 1- {4- [4-aryl (or heteroaryl) -1-piperazinyl] butyl} -1 H-azole derivatives and their physiologically acceptable salts, compulsive obsessive disorders, sleep apnea syndrome, sexual dysfunction, vomiting and It relates to the use of medicines to be used in the treatment of restraint.

TR97/00794T 1995-12-12 1996-12-11 1-(4-(4-Aryl (or heteroaryl)-1-piperazinyl butyl)-1H-azole derivatives, compulsive obsessive disorders, sleep apnea syndrome, sexual It is used in the preparation of a drug to be used in the treatment of dysfunction, vomiting and motion sickness. TR199700794T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514690A FR2742052B1 (en) 1995-12-12 1995-12-12 USE OF DERIVATIVES 1- (4- (4-ARYL (OR HETEROARYL) -1-PIPER AZINYL) -BUTY) -1H-AZOLE FOR THE TREATMENT OF DEPRESSION, OBSESSIVE COMPULSIVE DISORDERS, SLEEP APNEA, SEXUAL DYSFUNCTIONS , Emese and motion sickness

Publications (1)

Publication Number Publication Date
TR199700794T1 true TR199700794T1 (en) 1997-11-21

Family

ID=9485400

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/00794T TR199700794T1 (en) 1995-12-12 1996-12-11 1-(4-(4-Aryl (or heteroaryl)-1-piperazinyl butyl)-1H-azole derivatives, compulsive obsessive disorders, sleep apnea syndrome, sexual It is used in the preparation of a drug to be used in the treatment of dysfunction, vomiting and motion sickness.

Country Status (16)

Country Link
EP (1) EP0808166A1 (en)
JP (1) JPH11501051A (en)
CN (1) CN1177297A (en)
AR (1) AR004378A1 (en)
AU (1) AU716665B2 (en)
CA (1) CA2211161A1 (en)
CZ (1) CZ255197A3 (en)
ES (1) ES2134709B1 (en)
FR (1) FR2742052B1 (en)
HU (1) HUP9800198A2 (en)
IL (1) IL121461A0 (en)
NO (1) NO973589L (en)
PL (1) PL321779A1 (en)
TR (1) TR199700794T1 (en)
WO (1) WO1997021439A1 (en)
ZA (1) ZA9610457B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763950B1 (en) * 1997-06-02 2002-09-20 Esteve Labor Dr 2- {4- [4- (4,5-DICHLORO-2-METHYLIMIDAZOL-1-YL) BUTYL] -1- PIPERAZINYL} -5-FLUOROPYRIMIDINE, ITS PREPARATION AND THERAPEUTIC USE
TW526202B (en) * 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US6046331A (en) * 1998-12-17 2000-04-04 Synaptic Pharmaceutical Corporation Imidazolones and their use in treating benign prostatic hyperplasia and other disorders
JP5140225B2 (en) 2000-08-14 2013-02-06 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド Substituted pyrazoles
JP5049447B2 (en) 2000-08-14 2012-10-17 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド Substituted pyrazoles
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
WO2002014317A2 (en) 2000-08-14 2002-02-21 Ortho Mcneil Pharmaceutical, Inc. Substituted pyrazoles
MXPA03001960A (en) 2000-09-06 2004-03-18 Johnson & Johnson A method for treating allergies.
CA2580730C (en) 2003-09-25 2015-01-13 Cenomed, Inc. Tetrahydroindolone derivatives for treatment of neurological conditions
WO2005094827A1 (en) * 2004-03-30 2005-10-13 Kestrel Pharmaceuticals Inc. Methods for treating sexual dysfunction
WO2006116615A1 (en) 2005-04-26 2006-11-02 Hypnion, Inc. Benzisoxazole piperazine compounds and methods of use thereof
ATE461925T1 (en) 2005-04-26 2010-04-15 Hypnion Inc BENZISOXAZOLEPIPERIDINE COMPOUNDS AND METHOD FOR USE THEREOF
GB2435827A (en) * 2006-03-09 2007-09-12 Del Dr Esteve S A Spain Lab Use of substituted piperazine compounds for the treatment of food related disorders
CN115304590A (en) * 2022-09-19 2022-11-08 皮摩尔新药(辽宁)有限公司 2H-benzotriazole derivatives, preparation method thereof and pharmaceutical composition containing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672052B1 (en) * 1991-01-28 1995-05-24 Esteve Labor Dr DERIVATIVES OF ARYL (OR HETEROARYL) -PIPERAZINYL-ALKYL-AZOLES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS.
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES

Also Published As

Publication number Publication date
AR004378A1 (en) 1998-11-04
ES2134709B1 (en) 2000-05-16
CZ255197A3 (en) 1998-01-14
EP0808166A1 (en) 1997-11-26
AU1376497A (en) 1997-07-03
IL121461A0 (en) 1998-02-08
MX9706133A (en) 1997-11-29
HUP9800198A2 (en) 1999-09-28
FR2742052B1 (en) 1998-04-10
AU716665B2 (en) 2000-03-02
NO973589D0 (en) 1997-08-04
CA2211161A1 (en) 1997-06-19
ZA9610457B (en) 1997-06-24
PL321779A1 (en) 1997-12-22
WO1997021439A1 (en) 1997-06-19
JPH11501051A (en) 1999-01-26
FR2742052A1 (en) 1997-06-13
CN1177297A (en) 1998-03-25
NO973589L (en) 1997-10-08
ES2134709A1 (en) 1999-10-01

Similar Documents

Publication Publication Date Title
TR199700794T1 (en) 1-(4-(4-Aryl (or heteroaryl)-1-piperazinyl butyl)-1H-azole derivatives, compulsive obsessive disorders, sleep apnea syndrome, sexual It is used in the preparation of a drug to be used in the treatment of dysfunction, vomiting and motion sickness.
CA2430601A1 (en) Piperazine derivatives
NO2015009I1 (en) Nintedanib, tautomers and salts thereof, in particular Nintedanib and physiologically acceptable salts thereof, in particular Nintedanib esilate; 3-Z- [1- (4- (N - ((4-methylpiperazin-1-yl) -methylcarbonyl) -N-methylamino) -anilino) -1-phenylmethylene] -6-methoxycarbonyl-2-indolinone - See among other claims 1, 2, 5 (t) and 6 of the basic patent
NO324230B1 (en) Use of 1- [4- (5-cyanindol-3yl) butyl] -4- (2-carbamoylbenzofuran-5-yl) -piperazine and its physiologically acceptable salts for the preparation of drugs for the treatment of bipolar disorders and mania
ATE263763T1 (en) PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES, THEIR PREPARATION AND USE
DE69400435D1 (en) USE OF CARBAMAZEPINE AND OXCARBAZEPINE FOR THE TREATMENT OF PARKINSON AND THE PARKINSON SYNDROME
RU2003114752A (en) TREATMENT OF GASTROINTESTINAL STOMAL TUMORS
NO20035120D0 (en) 4- (Phenyl- (piperidin-4-yl) -amino) -benzamide derivatives and their use in the treatment of anxiety, pain or gastrointestinal disorders
MXPA04002825A (en) Quinoline derivatives as neuropeptide y antagonists.
DE60203197D1 (en) 4- (OXADIAZOL-3-YL) -1,4-DIAZABIZYKLO [3.2.2] NON-DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES
RU2218917C2 (en) Application of specific antagonist of 5ht2a-receptors for preparing drugs useful for treatment of sleep apnea syndrome
AU2003260744A1 (en) 1, 4- substituted piperidine derivatives and use thereof as base-inhibitors in treatment of alzheimer's disease
NO20015228L (en) Use of saredutant and its pharmaceutically acceptable salts for the manufacture of drugs used to treat or prevent mental disorders, adaptation disorders, or mixed anxiety-depression disorders
ZA949332B (en) Use of 1-{4-[4-aryl(or heteroaryl)-1-piperazinyl]-butyl}-1H-azole derivatives for the preparation of medicaments intended for the treatment of disorders of gastric secretion
NO20044049L (en) Preparation of N1- (2`-pyridyl) -1,2-propanediaminesulfamic acid and its use in the synthesis of biologically active piperazines
EP1393738A4 (en) Drugs for diabetes
EP1645273A3 (en) Novel use of (R)-(-)-2-(5-(-flourophenyl)-3-pyridylmethylaminoethyl|-chromane and its physiologically acceptable salts
NO20014475D0 (en) Method of treating sleep apnea
HUP0204391A2 (en) The use of mirtazapine for the preparation of pharmaceutical composition suitable for the treatment of sleep disorders
HRP20010764B1 (en) Prucalopride oral solution
FR2672286B1 (en) DERIVATIVES OF 1- (4-CHLOROPHENYL) -2- [4- (PHENYLMETHYL) PIPERIDIN-1-YL] ETHANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
RU2004112422A (en) ROUVASTATIN IN PREDEDENTIONAL CONDITIONS
NO20035114D0 (en) 4- (Phenyl- (piperidin-4-yl) -amino) -benzamide derivatives and their use in the treatment of anxiety, pain or gastrointestinal disorders
NO20035113D0 (en) 4- (Phenyl- (piperidin-4-yl) -amino) -benzamide derivatives and their use in the treatment of anxiety, pain or gastrointestinal disorders
NO20035112D0 (en) 4- (Phenyl- (piperidin-4-yl) -amino) -benzamide derivatives and their use in the treatment of pain, anxiety or gastrointestinal disorders