HUP0401782A2 - Új, vízmentes kristályos gabapentin formák - Google Patents
Új, vízmentes kristályos gabapentin formákInfo
- Publication number
- HUP0401782A2 HUP0401782A2 HU0401782A HUP0401782A HUP0401782A2 HU P0401782 A2 HUP0401782 A2 HU P0401782A2 HU 0401782 A HU0401782 A HU 0401782A HU P0401782 A HUP0401782 A HU P0401782A HU P0401782 A2 HUP0401782 A2 HU P0401782A2
- Authority
- HU
- Hungary
- Prior art keywords
- gabapentin
- crystalline forms
- anhydrous crystalline
- new
- new anhydrous
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002870 gabapentin Drugs 0.000 title abstract 2
- WRSFRDZQQUAKNA-UHFFFAOYSA-N 2-[1-(aminomethyl)cyclohexyl]acetic acid;hydrate Chemical compound O.OC(=O)CC1(CN)CCCCC1 WRSFRDZQQUAKNA-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A találmány tárgya új, kristályos, vízmentes A és B gabapentin formaés előállításuk gabapentin monohidrátból. Az új, kritályos formák acelebrális betegségek terápiájában hasznos gyógyszerkészítményekgyártásában előnyt biztosítanak.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32837501P | 2001-10-09 | 2001-10-09 | |
US10/256,155 US6800782B2 (en) | 2001-10-09 | 2002-09-25 | Anhydrous crystalline forms of gabapentin |
PCT/US2002/031706 WO2003031391A1 (en) | 2001-10-09 | 2002-10-03 | New anhydrous crystalline forms of gabapentin |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0401782A2 true HUP0401782A2 (hu) | 2005-10-28 |
HUP0401782A3 HUP0401782A3 (en) | 2006-01-30 |
Family
ID=26945177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0401782A HUP0401782A3 (en) | 2001-10-09 | 2002-10-03 | New anhydrous crystalline forms of gabapentin |
Country Status (27)
Country | Link |
---|---|
US (1) | US6800782B2 (hu) |
EP (1) | EP1463712A1 (hu) |
JP (1) | JP2005505594A (hu) |
KR (1) | KR20050033525A (hu) |
CN (1) | CN1568305A (hu) |
AP (1) | AP2004003025A0 (hu) |
BG (1) | BG108702A (hu) |
BR (1) | BR0213156A (hu) |
CA (1) | CA2462331A1 (hu) |
CO (1) | CO5570697A2 (hu) |
CZ (1) | CZ2004416A3 (hu) |
EA (1) | EA006557B1 (hu) |
GE (1) | GEP20063936B (hu) |
HR (1) | HRP20040408A2 (hu) |
HU (1) | HUP0401782A3 (hu) |
IL (1) | IL161099A0 (hu) |
IS (1) | IS7195A (hu) |
MA (1) | MA27072A1 (hu) |
MX (1) | MXPA04003301A (hu) |
NO (1) | NO20041370L (hu) |
NZ (1) | NZ531993A (hu) |
OA (1) | OA12665A (hu) |
PL (1) | PL368117A1 (hu) |
RS (1) | RS28204A (hu) |
SK (1) | SK1572004A3 (hu) |
TN (1) | TNSN04055A1 (hu) |
WO (1) | WO2003031391A1 (hu) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070043236A1 (en) * | 2003-05-19 | 2007-02-22 | Chandiran Thakashina M | Process for preparation of gabapentin |
WO2004106281A1 (en) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Crystalline gabapentin |
WO2004110342A2 (en) * | 2003-06-12 | 2004-12-23 | Matrix Laboratories Ltd | Novel polymorph of gabapentin and its conversion to gabapentin form-ii |
US7169812B2 (en) * | 2003-07-01 | 2007-01-30 | Medtronic, Inc. | Process for producing injectable gabapentin compositions |
ITMI20040579A1 (it) * | 2004-03-25 | 2004-06-25 | Zambon Spa | Processo di preparazione di gabapentina |
WO2010023694A2 (en) * | 2008-09-01 | 2010-03-04 | Hikal Ltd | Crystalline forms of gabapentin and process thereof |
CN104649921B (zh) * | 2015-01-14 | 2016-09-28 | 天津大学 | 一种加巴喷丁与己二酸共晶及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
JPS62247160A (ja) * | 1986-03-31 | 1987-10-28 | Aisin Seiki Co Ltd | スタ−リングエンジンの始動装置 |
US4960931A (en) * | 1988-05-02 | 1990-10-02 | Warner-Lambert Company | Gabapentin mohohydrate and a process for producing the same |
US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
IL119890A (en) | 1996-12-24 | 2002-03-10 | Teva Pharma | Gabapentin form iii and preparation of gabapentin form ii |
ES2137137B1 (es) | 1998-05-25 | 2000-08-16 | Medichem Sa | Nuevo polimorfo de gabapentina no hidratada, su procedimiento de obtencion y su utilizacion para la obtencion de gabapentina de calidad farmaceutica. |
-
2002
- 2002-09-25 US US10/256,155 patent/US6800782B2/en not_active Expired - Fee Related
- 2002-10-03 CN CNA02820056XA patent/CN1568305A/zh active Pending
- 2002-10-03 GE GE5594A patent/GEP20063936B/en unknown
- 2002-10-03 IL IL16109902A patent/IL161099A0/xx unknown
- 2002-10-03 KR KR1020047005149A patent/KR20050033525A/ko not_active Application Discontinuation
- 2002-10-03 OA OA1200400095A patent/OA12665A/en unknown
- 2002-10-03 PL PL02368117A patent/PL368117A1/xx not_active Application Discontinuation
- 2002-10-03 WO PCT/US2002/031706 patent/WO2003031391A1/en active Application Filing
- 2002-10-03 CA CA002462331A patent/CA2462331A1/en not_active Abandoned
- 2002-10-03 MX MXPA04003301A patent/MXPA04003301A/es active IP Right Grant
- 2002-10-03 HU HU0401782A patent/HUP0401782A3/hu unknown
- 2002-10-03 RS YU28204A patent/RS28204A/sr unknown
- 2002-10-03 BR BR0213156-0A patent/BR0213156A/pt not_active IP Right Cessation
- 2002-10-03 EP EP02766485A patent/EP1463712A1/en not_active Withdrawn
- 2002-10-03 EA EA200400417A patent/EA006557B1/ru not_active IP Right Cessation
- 2002-10-03 CZ CZ2004416A patent/CZ2004416A3/cs unknown
- 2002-10-03 NZ NZ531993A patent/NZ531993A/en unknown
- 2002-10-03 SK SK157-2004A patent/SK1572004A3/sk not_active Application Discontinuation
- 2002-10-03 JP JP2003534375A patent/JP2005505594A/ja active Pending
- 2002-10-03 AP APAP/P/2004/003025A patent/AP2004003025A0/en unknown
-
2004
- 2004-03-23 IS IS7195A patent/IS7195A/is unknown
- 2004-04-01 NO NO20041370A patent/NO20041370L/no not_active Application Discontinuation
- 2004-04-05 MA MA27606A patent/MA27072A1/fr unknown
- 2004-04-06 CO CO04032599A patent/CO5570697A2/es not_active Application Discontinuation
- 2004-04-07 TN TNP2004000055A patent/TNSN04055A1/fr unknown
- 2004-04-28 BG BG108702A patent/BG108702A/xx unknown
- 2004-05-07 HR HR20040408A patent/HRP20040408A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TNSN04055A1 (fr) | 2006-06-01 |
NO20041370L (no) | 2004-04-01 |
SK1572004A3 (sk) | 2005-03-04 |
EA006557B1 (ru) | 2006-02-24 |
CA2462331A1 (en) | 2003-04-17 |
JP2005505594A (ja) | 2005-02-24 |
HRP20040408A2 (en) | 2004-10-31 |
NZ531993A (en) | 2006-09-29 |
HUP0401782A3 (en) | 2006-01-30 |
IL161099A0 (en) | 2004-08-31 |
CZ2004416A3 (cs) | 2005-03-16 |
CN1568305A (zh) | 2005-01-19 |
EA200400417A1 (ru) | 2004-10-28 |
MXPA04003301A (es) | 2004-07-23 |
OA12665A (en) | 2006-06-19 |
RS28204A (en) | 2006-12-15 |
IS7195A (is) | 2004-03-23 |
GEP20063936B (en) | 2006-10-10 |
CO5570697A2 (es) | 2005-10-31 |
WO2003031391A1 (en) | 2003-04-17 |
US6800782B2 (en) | 2004-10-05 |
US20030092933A1 (en) | 2003-05-15 |
BG108702A (en) | 2005-05-31 |
PL368117A1 (en) | 2005-03-21 |
BR0213156A (pt) | 2004-09-14 |
KR20050033525A (ko) | 2005-04-12 |
EP1463712A1 (en) | 2004-10-06 |
MA27072A1 (fr) | 2004-12-20 |
AP2004003025A0 (en) | 2004-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |