HUP0300002A3 - Substituted piperidines, medicaments containing these compounds, and methods for the production thereof - Google Patents

Substituted piperidines, medicaments containing these compounds, and methods for the production thereof

Info

Publication number: HUP0300002A3
Authority: HU; Hungary
Prior art keywords: compounds; production; methods; medicaments containing; substituted piperidines
Prior art date: 1999-12-30

Application number

HU0300002A

Other languages

English (en)

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-30

Filing date

2000-12-22

Publication date

2006-01-30

2000-12-22 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2003-05-28 Publication of HUP0300002A2 publication Critical patent/HUP0300002A2/hu

2006-01-30 Publication of HUP0300002A3 publication Critical patent/HUP0300002A3/hu

Links

150000001875 compounds Chemical class 0.000 title 1
239000003814 drug Chemical class 0.000 title 1
150000003053 piperidines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Endocrinology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HU0300002A 1999-12-30 2000-12-22 Substituted piperidines, medicaments containing these compounds, and methods for the production thereof HUP0300002A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19963868A DE19963868A1 (de)	1999-12-30	1999-12-30	Neue substituierte Piperidine, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
PCT/EP2000/013236 WO2001049676A1 (de)	1999-12-30	2000-12-22	Substituierte piperidine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (2)

Publication Number	Publication Date
HUP0300002A2 HUP0300002A2 (en)	2003-05-28
HUP0300002A3 true HUP0300002A3 (en)	2006-01-30

Family

ID=7935059

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0300002A HUP0300002A3 (en)	1999-12-30	2000-12-22	Substituted piperidines, medicaments containing these compounds, and methods for the production thereof

Country Status (29)

Country	Link
US (1)	US6949541B2 (hu)
EP (1)	EP1252153A1 (hu)
JP (1)	JP2003519222A (hu)
KR (1)	KR100736063B1 (hu)
CN (1)	CN1203069C (hu)
AR (1)	AR027113A1 (hu)
AU (1)	AU783275B2 (hu)
BG (1)	BG106848A (hu)
BR (1)	BR0017063A (hu)
CA (1)	CA2395541C (hu)
CZ (1)	CZ20022628A3 (hu)
DE (1)	DE19963868A1 (hu)
EA (1)	EA005600B1 (hu)
EE (1)	EE200200369A (hu)
HK (1)	HK1054026A1 (hu)
HR (1)	HRP20020560A2 (hu)
HU (1)	HUP0300002A3 (hu)
IL (2)	IL150377A0 (hu)
MX (1)	MXPA02006509A (hu)
NO (1)	NO323700B1 (hu)
NZ (1)	NZ519939A (hu)
PL (1)	PL356400A1 (hu)
SK (1)	SK9412002A3 (hu)
TW (1)	TWI255267B (hu)
UA (1)	UA75346C2 (hu)
UY (1)	UY26513A1 (hu)
WO (1)	WO2001049676A1 (hu)
YU (1)	YU50002A (hu)
ZA (1)	ZA200205181B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10211770A1 (de) *	2002-03-14	2003-10-02	Boehringer Ingelheim Pharma	Neue substituierte Piperidine, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US7842808B2 (en) *	2002-06-05	2010-11-30	Bristol-Myers Squibb Company	Anti-migraine spirocycles
US20040063735A1 (en) *	2002-06-05	2004-04-01	Chaturvedula Prasad V.	Calcitonin gene related peptide receptor antagonists
US7220862B2 (en) *	2002-06-05	2007-05-22	Bristol-Myers Squibb Company	Calcitonin gene related peptide receptor antagonists
WO2004091514A2 (en) *	2003-04-15	2004-10-28	Merck & Co., Inc.	Cgrp receptor antagonists
CA2529196A1 (en) *	2003-06-26	2005-02-17	Merck & Co., Inc.	Benzodiazepine cgrp receptor antagonists
CN1812982B (zh) *	2003-06-26	2010-10-27	默沙东公司	苯并二氮杂*cgrp受体拮抗剂
EP1689493A4 (en)	2003-12-05	2008-04-23	Bristol Myers Squibb Co	ANTAGONISTS OF THE CALCITONIN GENE RELATED PEPTIDE RECEPTOR
TW200524601A (en) *	2003-12-05	2005-08-01	Bristol Myers Squibb Co	Heterocyclic anti-migraine agents
EP1695961A4 (en) *	2003-12-17	2007-10-24	Takeda Pharmaceutical	UREA DERIVATIVE, METHOD FOR THE PRODUCTION AND THEIR USE
AU2005208834B2 (en) *	2004-01-29	2009-10-08	Merck Sharp & Dohme Corp.	CGRP receptor antagonists
US20050192230A1 (en) *	2004-02-12	2005-09-01	Boehringer Ingelheim International Gambh	Process for preparing 1- [N²-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine
DE102004006893A1 (de) *	2004-02-12	2005-09-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung von 1[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazin
TW200533398A (en)	2004-03-29	2005-10-16	Bristol Myers Squibb Co	Novel therapeutic agents for the treatment of migraine
US7696192B2 (en) *	2004-09-09	2010-04-13	Merck Sharp & Dohme Corp.	Tricyclic anilide spirolactam CGRP receptor antagonists
AU2005285083B2 (en) *	2004-09-13	2011-03-10	Merck Sharp & Dohme Corp.	Tricyclic anilide spirohydantoin CGRP receptor antagonists
US7384930B2 (en)	2004-11-03	2008-06-10	Bristol-Myers Squibb Company	Constrained compounds as CGRP-receptor antagonists
US7384931B2 (en)	2004-11-03	2008-06-10	Bristol-Myers Squibb Company	Constrained compounds as CGRP-receptor antagonists
US7449586B2 (en) *	2004-12-03	2008-11-11	Bristol-Myers Squibb Company	Processes for the preparation of CGRP-receptor antagonists and intermediates thereof
EP1770091A1 (de) *	2005-09-29	2007-04-04	Boehringer Ingelheim Pharma GmbH & Co. KG	CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
US8291601B2 (en) *	2005-04-01	2012-10-23	Pankaj Kehr	Reusable metal blade handle
US7834007B2 (en) *	2005-08-25	2010-11-16	Bristol-Myers Squibb Company	CGRP antagonists
US8168592B2 (en) *	2005-10-21	2012-05-01	Amgen Inc.	CGRP peptide antagonists and conjugates
WO2023055827A1 (en) *	2021-09-30	2023-04-06	Crinetics Pharmaceuticals, Inc.	Parathyroid hormone (pth) receptor antagonists and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5011390A (hu) *	1973-05-30	1975-02-05
WO1996035713A1 (en) *	1995-05-08	1996-11-14	Pfizer, Inc.	Dipeptides which promote release of growth hormone
DE59711622D1 (de) *	1996-09-10	2004-06-17	Boehringer Ingelheim Pharma	Abgewandelte aminosäuren, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE19636623A1 (de) *	1996-09-10	1998-03-12	Thomae Gmbh Dr K	Abgewandelte Aminosäuren, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US6552043B1 (en) *	1998-09-30	2003-04-22	Merck Sharpe & Dohme Ltd.	Benzimidazolinyl piperidines as CGRP ligands
DE10250080A1 (de) *	2002-10-25	2004-05-13	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel

1999
- 1999-12-30 DE DE19963868A patent/DE19963868A1/de not_active Withdrawn
2000
- 2000-12-22 PL PL00356400A patent/PL356400A1/xx not_active Application Discontinuation
- 2000-12-22 MX MXPA02006509A patent/MXPA02006509A/es active IP Right Grant
- 2000-12-22 HU HU0300002A patent/HUP0300002A3/hu unknown
- 2000-12-22 AU AU35379/01A patent/AU783275B2/en not_active Ceased
- 2000-12-22 WO PCT/EP2000/013236 patent/WO2001049676A1/de active IP Right Grant
- 2000-12-22 IL IL15037700A patent/IL150377A0/xx active IP Right Grant
- 2000-12-22 US US10/169,009 patent/US6949541B2/en not_active Expired - Lifetime
- 2000-12-22 CA CA002395541A patent/CA2395541C/en not_active Expired - Fee Related
- 2000-12-22 BR BR0017063-1A patent/BR0017063A/pt active Pending
- 2000-12-22 SK SK941-2002A patent/SK9412002A3/sk not_active Application Discontinuation
- 2000-12-22 KR KR1020027008495A patent/KR100736063B1/ko not_active IP Right Cessation
- 2000-12-22 EA EA200200651A patent/EA005600B1/ru not_active IP Right Cessation
- 2000-12-22 EE EEP200200369A patent/EE200200369A/xx unknown
- 2000-12-22 NZ NZ519939A patent/NZ519939A/en unknown
- 2000-12-22 JP JP2001550216A patent/JP2003519222A/ja active Pending
- 2000-12-22 YU YU50002A patent/YU50002A/sh unknown
- 2000-12-22 CZ CZ20022628A patent/CZ20022628A3/cs unknown
- 2000-12-22 EP EP00991806A patent/EP1252153A1/de not_active Withdrawn
- 2000-12-22 CN CNB008181063A patent/CN1203069C/zh not_active Expired - Fee Related
- 2000-12-22 UA UA2002076283A patent/UA75346C2/uk unknown
- 2000-12-27 AR ARP000106941A patent/AR027113A1/es not_active Suspension/Interruption
- 2000-12-28 UY UY26513A patent/UY26513A1/es not_active Application Discontinuation
- 2000-12-28 TW TW089128135A patent/TWI255267B/zh not_active IP Right Cessation
2002
- 2002-06-20 BG BG106848A patent/BG106848A/bg active Pending
- 2002-06-24 IL IL150377A patent/IL150377A/en not_active IP Right Cessation
- 2002-06-27 ZA ZA200205181A patent/ZA200205181B/en unknown
- 2002-06-27 HR HR20020560A patent/HRP20020560A2/hr not_active Application Discontinuation
- 2002-06-28 NO NO20023161A patent/NO323700B1/no unknown
2003
- 2003-09-01 HK HK03106237A patent/HK1054026A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU783275B2 (en)	2005-10-06
BG106848A (bg)	2002-12-29
HRP20020560A2 (en)	2005-04-30
NZ519939A (en)	2006-08-31
HK1054026A1 (en)	2003-11-14
CA2395541C (en)	2008-09-23
DE19963868A1 (de)	2001-07-12
CN1203069C (zh)	2005-05-25
SK9412002A3 (en)	2002-11-06
TWI255267B (en)	2006-05-21
BR0017063A (pt)	2002-10-22
HUP0300002A2 (en)	2003-05-28
CN1414960A (zh)	2003-04-30
EE200200369A (et)	2003-10-15
UA75346C2 (en)	2006-04-17
AR027113A1 (es)	2003-03-12
JP2003519222A (ja)	2003-06-17
IL150377A0 (en)	2002-12-01
NO20023161L (no)	2002-06-28
PL356400A1 (en)	2004-06-28
MXPA02006509A (es)	2002-11-29
EA200200651A1 (ru)	2002-12-26
KR100736063B1 (ko)	2007-07-06
IL150377A (en)	2007-06-17
NO323700B1 (no)	2007-06-25
CZ20022628A3 (cs)	2002-10-16
CA2395541A1 (en)	2001-07-12
US20030212057A1 (en)	2003-11-13
UY26513A1 (es)	2001-07-31
US6949541B2 (en)	2005-09-27
EA005600B1 (ru)	2005-04-28
WO2001049676A1 (de)	2001-07-12
KR20020073493A (ko)	2002-09-26
YU50002A (sh)	2005-11-28
EP1252153A1 (de)	2002-10-30
ZA200205181B (en)	2003-09-30
AU3537901A (en)	2001-07-16
NO20023161D0 (no)	2002-06-28

Legal Events

Date

Code

Title

Description

2006-02-28

FH91

Appointment of a representative

Free format text: FORMER REPRESENTATIVE(S): BELICZAY LASZLO, S.B.G. & K. SZABADALMI UEGYVIVOEI IRODA, HU

Representative=s name: DR. LANG TIVADARNE, S.B.G. & K. SZABADALMI UEG, HU