HUE063621T2 - ß-interferon elleni ellenanyagok és alkalmazásuk - Google Patents

ß-interferon elleni ellenanyagok és alkalmazásuk

Info

Publication number
HUE063621T2
HUE063621T2 HUE17733171A HUE17733171A HUE063621T2 HU E063621 T2 HUE063621 T2 HU E063621T2 HU E17733171 A HUE17733171 A HU E17733171A HU E17733171 A HUE17733171 A HU E17733171A HU E063621 T2 HUE063621 T2 HU E063621T2
Authority
HU
Hungary
Prior art keywords
interferon beta
beta antibodies
antibodies
interferon
beta
Prior art date
Application number
HUE17733171A
Other languages
English (en)
Inventor
Stefano V Gulla
Christine Huard
Janet Elizabeth Buhlmann
Juan Carlos Almagro
Sreekumar R Kodangattil
Steven A Greenberg
Edward Roland Lavallie
Eric M Bennett
Lidia Mosyak
Jame Perry Hall
Anthony John Coyle
Original Assignee
Pfizer
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Brigham & Womens Hospital Inc filed Critical Pfizer
Publication of HUE063621T2 publication Critical patent/HUE063621T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HUE17733171A 2016-04-29 2017-04-28 ß-interferon elleni ellenanyagok és alkalmazásuk HUE063621T2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662329327P 2016-04-29 2016-04-29
US201662339709P 2016-05-20 2016-05-20
US201762483669P 2017-04-10 2017-04-10

Publications (1)

Publication Number Publication Date
HUE063621T2 true HUE063621T2 (hu) 2024-01-28

Family

ID=59215947

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17733171A HUE063621T2 (hu) 2016-04-29 2017-04-28 ß-interferon elleni ellenanyagok és alkalmazásuk

Country Status (29)

Country Link
US (3) US10829553B2 (hu)
EP (2) EP3448419B1 (hu)
JP (2) JP6799076B2 (hu)
KR (1) KR102527840B1 (hu)
CN (1) CN109069606B (hu)
AU (1) AU2017258492B2 (hu)
BR (1) BR112018072118A2 (hu)
CA (1) CA2965652A1 (hu)
CO (1) CO2018012497A2 (hu)
DK (1) DK3448419T3 (hu)
ES (1) ES2950288T3 (hu)
FI (1) FI3448419T3 (hu)
HR (1) HRP20230605T1 (hu)
HU (1) HUE063621T2 (hu)
IL (1) IL262244B2 (hu)
MX (1) MX2018013222A (hu)
MY (1) MY194084A (hu)
NZ (1) NZ747225A (hu)
PE (1) PE20190371A1 (hu)
PH (1) PH12018502275A1 (hu)
PL (1) PL3448419T3 (hu)
PT (1) PT3448419T (hu)
RU (1) RU2750454C2 (hu)
SA (1) SA518400327B1 (hu)
SG (1) SG11201809456UA (hu)
SI (1) SI3448419T1 (hu)
TW (1) TWI776808B (hu)
WO (1) WO2017189983A1 (hu)
ZA (1) ZA201806682B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2950288T3 (es) 2016-04-29 2023-10-06 Pfizer Anticuerpos interferón beta y usos de los mismos
EP3672986A1 (en) 2017-08-22 2020-07-01 Sanabio, LLC Soluble interferon receptors and uses thereof
WO2019209995A2 (en) 2018-04-25 2019-10-31 Precision Ibd, Inc. Optimized anti-tl1a antibodies
CN116333132A (zh) * 2019-01-31 2023-06-27 广东旋玉健康生物科技有限公司 新型抗ifnar1抗体
BR112022007720A2 (pt) 2019-10-24 2022-08-23 Prometheus Biosciences Inc Anticorpos humanizados para ligante 1a tnf-like (tl1a) e seus usos
CN114733455B (zh) * 2022-04-15 2023-02-14 北京田园奥瑞生物科技有限公司 一种利用生物改性β-环糊精纳米磁颗粒进行快速哺乳动物***分型的方法
WO2024062420A1 (en) * 2022-09-22 2024-03-28 Pfizer Inc. METHODS OF TREATMENT WITH IFNß ANTIBODIES

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4754065A (en) 1984-12-18 1988-06-28 Cetus Corporation Precursor to nucleic acid probe
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
JP2717319B2 (ja) * 1988-10-14 1998-02-18 ベルレックス、ラボラトリーズ、インコーポレイテッド Ｒ―ｉｆｎ―ベータエピトープ部位を代表するペプチド、それに対する抗体、およびその用途
US6682896B1 (en) * 1988-10-14 2004-01-27 Schering Aktiengesellschaft Peptides representing epitopic sites on r-IFN-β, antibodies thereto and uses thereof
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL108584A (en) * 1994-02-07 2008-03-20 Yeda Res & Dev Cloning of the interferon-binding protein ALPHA / BETA
ZA9811070B (en) * 1997-12-08 2000-07-03 Genentech Inc Type I interferons.
WO2003048731A2 (en) 2001-12-03 2003-06-12 Abgenix, Inc. Antibody categorization based on binding characteristics
WO2003080672A1 (en) 2002-03-22 2003-10-02 Aprogen, Inc. Humanized antibody and process for preparing same
KR101250818B1 (ko) 2002-12-24 2013-04-15 리나트 뉴로사이언스 코프. 항-ｎｇｆ 항체 및 그것을 이용하는 방법
JP2014516511A (ja) * 2011-04-07 2014-07-17 ジェネンテック， インコーポレイテッド 抗ｆｇｆｒ４抗体及び使用方法
CN102898521A (zh) * 2011-07-26 2013-01-30 上海市免疫学研究所 抗β-干扰素单克隆抗体及其应用
US10647756B2 (en) 2015-05-18 2020-05-12 Pfizer Inc. Humanized antibodies
IL256424B1 (en) * 2015-06-26 2024-05-01 Bioverativ Usa Inc Methods for treating autoimmune and alloimmune disorders
ES2950288T3 (es) 2016-04-29 2023-10-06 Pfizer Anticuerpos interferón beta y usos de los mismos

Also Published As

Publication number Publication date
MX2018013222A (es) 2019-04-22
PH12018502275A1 (en) 2019-09-09
US10829553B2 (en) 2020-11-10
CN109069606B (zh) 2022-07-01
JP6799076B2 (ja) 2020-12-09
WO2017189983A1 (en) 2017-11-02
RU2750454C2 (ru) 2021-06-28
TW201739764A (zh) 2017-11-16
KR102527840B1 (ko) 2023-05-03
RU2018141839A (ru) 2020-05-29
EP3448419B1 (en) 2023-06-07
IL262244B2 (en) 2024-01-01
ES2950288T3 (es) 2023-10-06
PT3448419T (pt) 2023-07-26
TWI776808B (zh) 2022-09-11
BR112018072118A2 (pt) 2019-03-19
AU2017258492B2 (en) 2023-12-07
CN109069606A (zh) 2018-12-21
RU2018141839A3 (hu) 2020-10-16
FI3448419T3 (fi) 2023-08-02
CA2965652A1 (en) 2017-10-29
MY194084A (en) 2022-11-11
JP2019516366A (ja) 2019-06-20
KR20190003625A (ko) 2019-01-09
SA518400327B1 (ar) 2022-12-03
US20210163588A1 (en) 2021-06-03
US20240174742A1 (en) 2024-05-30
HRP20230605T1 (hr) 2023-09-29
CO2018012497A2 (es) 2018-12-14
IL262244B1 (en) 2023-09-01
DK3448419T3 (da) 2023-06-26
EP4273165A3 (en) 2023-12-20
IL262244A (en) 2018-11-29
ZA201806682B (en) 2022-05-25
EP3448419A1 (en) 2019-03-06
EP4273165A2 (en) 2023-11-08
NZ747225A (en) 2022-07-29
SI3448419T1 (sl) 2023-10-30
SG11201809456UA (en) 2018-11-29
PE20190371A1 (es) 2019-03-08
US20170313769A1 (en) 2017-11-02
US11858986B2 (en) 2024-01-02
AU2017258492A1 (en) 2018-10-25
JP2021040642A (ja) 2021-03-18
PL3448419T3 (pl) 2023-09-04
JP7102489B2 (ja) 2022-07-19

Similar Documents

Publication Publication Date Title
IL290842A (en) Anti-cd73 antibodies and uses thereof
IL312910A (en) Anti-galectin-9 antibodies and their uses
IL266738A (en) Novel antibodies and their uses
IL262095A (en) Anti-pacap antibodies and their use
IL268734A (en) Anti-LAG-3 antibodies and uses thereof
IL268700A (en) Anti-PHF-tau antibodies and uses thereof
IL271477A (en) Anti-cd166 antibodies and their uses
IL263273A (en) Antibodies against gitr and their uses
ZA201901935B (en) Anti-il-33 antibodies and uses thereof
IL269134B2 (en) Antibodies against PAR2 and their use
IL262244B1 (en) Antibodies against beta interferon and their use
IL272476A (en) Anti-Apelin antibodies and their uses
IL273157A (en) Antibodies specific to AXL and their uses
IL271398A (en) Anti-l1-cam antibodies and uses thereof
IL266049A (en) Antibodies against o1 and their uses
IL265383A (en) New antibodies against factor xi and their uses
IL266082A (en) Anti-chikv antibodies and their use
IL264417A (en) Anti-o2 antibodies and their uses
GB201712032D0 (en) Antibodies and uses thereof
GB201615335D0 (en) Antibodies and immunocytokines