HU9901911D0 - Diaza-spiro[3,5]nanone derivatives - Google Patents

Diaza-spiro[3,5]nanone derivatives

Info

Publication number
HU9901911D0
HU9901911D0 HU9901911A HUP9901911A HU9901911D0 HU 9901911 D0 HU9901911 D0 HU 9901911D0 HU 9901911 A HU9901911 A HU 9901911A HU P9901911 A HUP9901911 A HU P9901911A HU 9901911 D0 HU9901911 D0 HU 9901911D0
Authority
HU
Hungary
Prior art keywords
nanone
diaza
spiro
derivatives
nanone derivatives
Prior art date
Application number
HU9901911A
Other languages
English (en)
Inventor
Geo Adam
Andrea Cesura
Francois Jenck
Sabine Kolczewski
Stephan Roever
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HU9901911D0 publication Critical patent/HU9901911D0/hu
Publication of HUP9901911A1 publication Critical patent/HUP9901911A1/hu
Publication of HU220894B1 publication Critical patent/HU220894B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
HU9901911A 1998-06-12 1999-06-09 Orphanin fq (ofq) receptor agonist and/or antagonist diaza-spiro[3,5]nonane derivatives, preparation and use thereof HU220894B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98110804 1998-06-12

Publications (3)

Publication Number Publication Date
HU9901911D0 true HU9901911D0 (en) 1999-08-30
HUP9901911A1 HUP9901911A1 (hu) 2000-05-28
HU220894B1 HU220894B1 (en) 2002-06-29

Family

ID=8232114

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901911A HU220894B1 (en) 1998-06-12 1999-06-09 Orphanin fq (ofq) receptor agonist and/or antagonist diaza-spiro[3,5]nonane derivatives, preparation and use thereof

Country Status (28)

Country Link
US (1) US6113527A (hu)
EP (1) EP0970957B1 (hu)
JP (1) JP3286268B2 (hu)
KR (1) KR100344732B1 (hu)
CN (1) CN1107066C (hu)
AR (1) AR019859A1 (hu)
AT (1) ATE204279T1 (hu)
AU (1) AU743983B2 (hu)
BR (1) BR9902651A (hu)
CA (1) CA2274202A1 (hu)
DE (1) DE69900220T2 (hu)
DK (1) DK0970957T3 (hu)
ES (1) ES2162503T3 (hu)
HR (1) HRP990188A2 (hu)
HU (1) HU220894B1 (hu)
ID (1) ID23304A (hu)
IL (1) IL130377A0 (hu)
MA (1) MA26644A1 (hu)
NO (1) NO312590B1 (hu)
NZ (1) NZ336189A (hu)
PE (1) PE20000548A1 (hu)
PL (1) PL333695A1 (hu)
PT (1) PT970957E (hu)
SG (1) SG79259A1 (hu)
SI (1) SI0970957T1 (hu)
TR (1) TR199901381A3 (hu)
YU (1) YU26499A (hu)
ZA (1) ZA993852B (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030040479A1 (en) * 2001-07-02 2003-02-27 Omeros Corporation Rotational intrathecal analgesia method and device
WO2003004034A1 (en) * 2001-07-02 2003-01-16 Omeros Corporation Method for inducing analgesia comprising administration alternatively of an opioid receptor agonist and an opioid receptor like receptor 1 agonist for and an implantable infusion pump
US7566728B2 (en) * 2002-03-29 2009-07-28 Mitsubishi Tanabe Pharma Corporation Remedy for sleep disturbance
JP2005289816A (ja) 2002-05-14 2005-10-20 Banyu Pharmaceut Co Ltd ベンズイミダゾール誘導体
SI1519939T1 (sl) * 2002-07-05 2010-04-30 Targacept Inc N-aril diazaspiracikliŽŤne spojine in postopki za njihovo pripravo in njihova uporaba
MXPA05002622A (es) * 2002-09-09 2005-09-08 Johnson & Johnson Derivados de 1,3,8,-triazaespiro [4.5]decan-4-ona sustituidos con hidroxialquilo utiles para el tratamiento de desordenes mediados por el receptor opioide huerfano.
GB0323204D0 (en) 2003-10-03 2003-11-05 Novartis Ag Organic compounds
US20050228023A1 (en) * 2003-12-19 2005-10-13 Sri International Agonist and antagonist ligands of the nociceptin receptor
US20060178390A1 (en) * 2004-08-02 2006-08-10 Alfonzo Jordan 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
BRPI0514509A (pt) * 2004-08-20 2008-06-10 Targacept Inc uso de composto n-aril diazaespiracìclicos no tratamento de dependência
US20080247964A1 (en) * 2006-05-08 2008-10-09 Yuelian Xu Substituted azaspiro derivatives
MX2009005641A (es) * 2006-11-28 2009-06-05 Janssen Pharmaceutica Nv Sales de 3-(3-amino-2-(r)-hidroxi-propil)-1-(4-fluoro-fenil)-8-(8- metil-naftalen-1-ilmetil)-1,3,8-triaza-espiro[4,5]deca n-4-ona.
MX2009011006A (es) * 2007-04-09 2009-11-02 Janssen Pharmaceutica Nv Derivados de 1,3,8-trisustituido-1,3,8-triaza-espiro[4.5]decano-4- ona como ligandos del receptor de orl-1 para el tratamiento de ansiedad y depresion.
KR101704226B1 (ko) 2015-06-30 2017-02-07 현대자동차주식회사 자동차의 쿼터글라스 어셈블리
TW202340202A (zh) * 2021-12-22 2023-10-16 美國加利福尼亞大學董事會 Gtp酶抑制劑及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756743A (en) * 1996-04-10 1998-05-26 Hoechst Marion Roussel Inc. Spiro cyclopent b!indole-piperidines!

Also Published As

Publication number Publication date
ES2162503T3 (es) 2001-12-16
CN1242366A (zh) 2000-01-26
KR100344732B1 (ko) 2002-07-19
DE69900220D1 (de) 2001-09-20
HUP9901911A1 (hu) 2000-05-28
CN1107066C (zh) 2003-04-30
ATE204279T1 (de) 2001-09-15
YU26499A (sh) 2002-09-19
TR199901381A2 (xx) 2000-01-21
DE69900220T2 (de) 2002-05-08
BR9902651A (pt) 2000-05-16
NO992873L (no) 1999-12-13
SG79259A1 (en) 2001-03-20
KR20000006060A (ko) 2000-01-25
US6113527A (en) 2000-09-05
PT970957E (pt) 2002-02-28
IL130377A0 (en) 2000-06-01
ZA993852B (en) 1999-12-13
EP0970957B1 (en) 2001-08-16
HU220894B1 (en) 2002-06-29
AU743983B2 (en) 2002-02-14
AU3498799A (en) 1999-12-23
ID23304A (id) 2000-04-05
PL333695A1 (en) 1999-12-20
JP2000053679A (ja) 2000-02-22
NO992873D0 (no) 1999-06-11
AR019859A1 (es) 2002-03-20
CA2274202A1 (en) 1999-12-12
TR199901381A3 (tr) 2000-01-21
EP0970957A1 (en) 2000-01-12
PE20000548A1 (es) 2000-07-15
NZ336189A (en) 2000-10-27
JP3286268B2 (ja) 2002-05-27
NO312590B1 (no) 2002-06-03
DK0970957T3 (da) 2001-12-03
SI0970957T1 (hu) 2001-12-31
HRP990188A2 (en) 2000-02-29
MA26644A1 (fr) 2004-12-20

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee