HRP920903B1 - Indenoindole compounds and a process for preparing the same - Google Patents

Indenoindole compounds and a process for preparing the same

Info

Publication number: HRP920903B1
Authority: HR; Croatia
Prior art keywords: lower alkyl; hydrogen; group; cor; alkyl group
Prior art date: 1989-06-22

Application number

HRP-1223/90A

Other languages

English (en)

Inventor

Howard G Shertzer

Original Assignee

Howard G. Shertzer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-22

Filing date

1992-10-02

Publication date

1998-06-30

1992-10-02 Application filed by Howard G. Shertzer filed Critical Howard G. Shertzer

1994-04-30 Publication of HRP920903A2 publication Critical patent/HRP920903A2/hr

1998-06-30 Publication of HRP920903B1 publication Critical patent/HRP920903B1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

HRP-1223/90A 1989-06-22 1992-10-02 Indenoindole compounds and a process for preparing the same HRP920903B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8902274A SE8902274D0 (sv)	1989-06-22	1989-06-22	Indenoidole compounds ii
YU122390A YU122390A (sh)	1989-06-22	1990-06-22	Indenoindolova jedinjenja ii

Publications (2)

Publication Number	Publication Date
HRP920903A2 HRP920903A2 (hr)	1994-04-30
HRP920903B1 true HRP920903B1 (en)	1998-06-30

Family

ID=20376370

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP-1223/90A HRP920903B1 (en)	1989-06-22	1992-10-02	Indenoindole compounds and a process for preparing the same

Country Status (34)

Country	Link
EP (1)	EP0409410B1 (xx)
JP (1)	JP3064411B2 (xx)
KR (1)	KR920702679A (xx)
CN (1)	CN1033029C (xx)
AT (1)	ATE135688T1 (xx)
BG (1)	BG60317B2 (xx)
CA (1)	CA2060897A1 (xx)
DD (1)	DD297960A5 (xx)
DE (1)	DE69025998T2 (xx)
DK (1)	DK0409410T3 (xx)
DZ (1)	DZ1428A1 (xx)
ES (1)	ES2084660T3 (xx)
FI (1)	FI100800B (xx)
GR (1)	GR3019779T3 (xx)
HR (1)	HRP920903B1 (xx)
HU (1)	HUT59097A (xx)
IE (1)	IE74682B1 (xx)
IL (1)	IL94830A (xx)
IS (1)	IS3590A7 (xx)
LT (1)	LT3675B (xx)
LV (1)	LV10253B (xx)
MX (1)	MX21244A (xx)
MY (1)	MY107311A (xx)
NO (1)	NO177932C (xx)
NZ (1)	NZ234175A (xx)
PL (1)	PL167761B1 (xx)
PT (1)	PT94468B (xx)
RO (1)	RO111573B1 (xx)
RU (1)	RU2104270C1 (xx)
SE (1)	SE8902274D0 (xx)
SI (1)	SI9011223B (xx)
WO (1)	WO1990015799A1 (xx)
YU (1)	YU122390A (xx)
ZA (1)	ZA904827B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT99232A (pt) *	1990-10-16	1992-09-30	Univ Bath	Processo de preparacao de compostos de indeno-indolo de composicoes farmaceuticas, e de estabilizacao de compostos susceptiveis de deterioracao oxidadtiva
JPH0656669A (ja) *	1992-06-11	1994-03-01	Asahi Breweries Ltd	活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) *	1993-07-16	1993-07-16	Ab Astra	Use of indenoindole compounds
CA2128283A1 (fr) *	1993-07-20	1995-01-21	Paul Caubere	(thia)cycloalkyl¬b\|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1135393A2 (en) *	1998-12-04	2001-09-26	American Home Products Corporation	Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
US6288099B1 (en)	1998-12-04	2001-09-11	American Home Products Corporation	Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) *	2001-06-13	2003-08-15	Servier Lab	Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR20080028929A (ko)	2005-07-14	2008-04-02	아이알엠 엘엘씨	Ｔｐｏ 모방체로서의 헤테로테트라시클릭 화합물
DE102006047231B4 (de) *	2006-10-04	2009-02-12	Hemmerling, Hans-Jörg, Dr.	Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
EP2722042B1 (en) *	2011-06-16	2019-05-29	Korea Research Institute of Chemical Technology	Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
EP2933254B1 (en)	2012-12-14	2021-01-20	Korea Research Institute of Chemical Technology	Novel compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient

1989
- 1989-06-22 SE SE8902274A patent/SE8902274D0/xx unknown
1990
- 1990-06-13 IS IS3590A patent/IS3590A7/is unknown
- 1990-06-20 CA CA002060897A patent/CA2060897A1/en not_active Abandoned
- 1990-06-20 PL PL90285752A patent/PL167761B1/pl unknown
- 1990-06-20 RU SU5010937A patent/RU2104270C1/ru active
- 1990-06-20 AT AT90306718T patent/ATE135688T1/de active
- 1990-06-20 JP JP2508940A patent/JP3064411B2/ja not_active Expired - Fee Related
- 1990-06-20 WO PCT/GB1990/000949 patent/WO1990015799A1/en active IP Right Grant
- 1990-06-20 EP EP90306718A patent/EP0409410B1/en not_active Expired - Lifetime
- 1990-06-20 DZ DZ900114A patent/DZ1428A1/fr active
- 1990-06-20 HU HU904825A patent/HUT59097A/hu unknown
- 1990-06-20 DK DK90306718.9T patent/DK0409410T3/da active
- 1990-06-20 RO RO149127A patent/RO111573B1/ro unknown
- 1990-06-20 MX MX21244A patent/MX21244A/es unknown
- 1990-06-20 IE IE224790A patent/IE74682B1/en not_active IP Right Cessation
- 1990-06-20 DE DE69025998T patent/DE69025998T2/de not_active Expired - Fee Related
- 1990-06-20 ES ES90306718T patent/ES2084660T3/es not_active Expired - Lifetime
- 1990-06-21 DD DD90341939A patent/DD297960A5/de not_active IP Right Cessation
- 1990-06-21 NZ NZ234175A patent/NZ234175A/xx unknown
- 1990-06-21 MY MYPI90001050A patent/MY107311A/en unknown
- 1990-06-21 ZA ZA904827A patent/ZA904827B/xx unknown
- 1990-06-21 IL IL9483090A patent/IL94830A/en not_active IP Right Cessation
- 1990-06-22 PT PT94468A patent/PT94468B/pt not_active IP Right Cessation
- 1990-06-22 SI SI9011223A patent/SI9011223B/sl unknown
- 1990-06-22 CN CN90104933A patent/CN1033029C/zh not_active Expired - Fee Related
- 1990-06-22 YU YU122390A patent/YU122390A/sh unknown
1991
- 1991-12-19 FI FI915999A patent/FI100800B/fi active
- 1991-12-20 NO NO915049A patent/NO177932C/no unknown
- 1991-12-20 BG BG95667A patent/BG60317B2/bg unknown
- 1991-12-23 KR KR1019910701951A patent/KR920702679A/ko not_active Application Discontinuation
1992
- 1992-10-02 HR HRP-1223/90A patent/HRP920903B1/xx not_active IP Right Cessation
1993
- 1993-06-14 LV LVP-93-568A patent/LV10253B/xx unknown
- 1993-08-30 LT LTIP912A patent/LT3675B/lt not_active IP Right Cessation
1996
- 1996-04-29 GR GR960401159T patent/GR3019779T3/el unknown

Also Published As

Publication number	Publication date
PL167761B1 (pl)	1995-10-31
BG60317B2 (bg)	1994-05-27
LT3675B (en)	1996-01-25
DD297960A5 (de)	1992-01-30
DK0409410T3 (da)	1996-04-29
PT94468B (pt)	1997-12-31
EP0409410A1 (en)	1991-01-23
DZ1428A1 (fr)	2004-09-13
EP0409410B1 (en)	1996-03-20
PL285752A1 (en)	1991-03-11
NZ234175A (en)	1992-12-23
KR920702679A (ko)	1992-10-06
JPH04505923A (ja)	1992-10-15
NO915049D0 (no)	1991-12-20
SE8902274D0 (sv)	1989-06-22
SI9011223B (sl)	1998-08-31
RO111573B1 (ro)	1996-11-29
AU5836990A (en)	1991-01-08
NO177932B (no)	1995-09-11
ATE135688T1 (de)	1996-04-15
YU122390A (sh)	1992-09-07
SI9011223A (en)	1997-10-31
HU904825D0 (en)	1992-03-30
DE69025998T2 (de)	1996-08-08
CN1033029C (zh)	1996-10-16
RU2104270C1 (ru)	1998-02-10
MY107311A (en)	1995-11-30
DE69025998D1 (de)	1996-04-25
LTIP912A (en)	1995-03-27
IE74682B1 (en)	1997-07-30
LV10253B (en)	1995-04-20
AU644084B2 (en)	1993-12-02
MX21244A (es)	1994-03-31
NO177932C (no)	1995-12-20
FI915999A0 (fi)	1991-12-19
HRP920903A2 (hr)	1994-04-30
GR3019779T3 (en)	1996-07-31
WO1990015799A1 (en)	1990-12-27
JP3064411B2 (ja)	2000-07-12
LV10253A (lv)	1994-10-20
HUT59097A (en)	1992-04-28
IL94830A (en)	1996-07-23
IE902247L (en)	1990-12-22
ES2084660T3 (es)	1996-05-16
CA2060897A1 (en)	1990-12-23
CN1051554A (zh)	1991-05-22
PT94468A (pt)	1991-02-08
IS3590A7 (is)	1990-12-23
IE902247A1 (en)	1991-01-16
NO915049L (no)	1992-02-21
IL94830A0 (en)	1991-04-15
FI100800B (fi)	1998-02-27
ZA904827B (en)	1991-04-24

Legal Events

Date	Code	Title	Description
1994-04-30	A1OB	Publication of a patent application
1994-10-17	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
1998-06-22	ODRP	Renewal fee for the maintenance of a patent	Payment date: 19980622 Year of fee payment: 9
1998-06-30	B1PR	Patent granted
1999-12-23	PBON	Lapse due to non-payment of renewal fee	Effective date: 19990623

Publication	Publication Date	Title
EP0163599A3 (en)	1987-02-25	Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents
GR3004139T3 (xx)	1993-03-31
HRP920903B1 (en)	1998-06-30	Indenoindole compounds and a process for preparing the same
ZA853719B (en)	1986-01-29	New beta-carboline-3-oxadiazolyl derivatives,method of preparing the same and their use
EP0161575A3 (en)	1987-03-25	B-carboline-3-carboxylic acid derivatives, method of preparing the same and their use
SE8902273D0 (sv)	1989-06-22	Indenoindole compounds i
GR3003126T3 (en)	1993-02-17	Quinolinecarboxylic acid derivatives, a composition comprising the same, process for preparing the same, and the use of the same for the manufacture of medicaments
JO1676B1 (en)	1992-08-09	Extra compounds indinol II
EP0470832A3 (en)	1992-11-19	Biphenyl 5, 5'-bis-alkanoic acid derivatives, their production and use thereof
DE3362523D1 (en)	1986-04-17	Optically active imidazolylpropanol compounds, and their production and use
HUT47897A (en)	1989-04-28	Process for producing salicilates and pharmaceutical compositions containing them