HRP20221051T8 - Heterociklički spojevi kao inhibitori ret kinaze - Google Patents

Heterociklički spojevi kao inhibitori ret kinaze Download PDF

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Publication number
HRP20221051T8
HRP20221051T8 HRP20221051TT HRP20221051T HRP20221051T8 HR P20221051 T8 HRP20221051 T8 HR P20221051T8 HR P20221051T T HRP20221051T T HR P20221051TT HR P20221051 T HRP20221051 T HR P20221051T HR P20221051 T8 HRP20221051 T8 HR P20221051T8
Authority
HR
Croatia
Prior art keywords
kinase inhibitors
heterocyclic compounds
ret kinase
ret
heterocyclic
Prior art date
Application number
HRP20221051TT
Other languages
English (en)
Inventor
Allan Jordan
Rebecca NEWTON
Bohdan Waszkowycz
Jonathan Mark Sutton
George Hynd
Silvia PAOLETTA
Euan Alexander Fraser Fordyce
Original Assignee
Cancer Research Technology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Technology Limited filed Critical Cancer Research Technology Limited
Publication of HRP20221051T1 publication Critical patent/HRP20221051T1/hr
Publication of HRP20221051T8 publication Critical patent/HRP20221051T8/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
HRP20221051TT 2016-04-15 2017-04-18 Heterociklički spojevi kao inhibitori ret kinaze HRP20221051T8 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201606635 2016-04-15
PCT/GB2017/051077 WO2017178845A1 (en) 2016-04-15 2017-04-18 Heterocyclic compounds as ret kinase inhibitors
EP17719688.8A EP3442535B1 (en) 2016-04-15 2017-04-18 Heterocyclic compounds as ret kinase inhibitors

Publications (2)

Publication Number Publication Date
HRP20221051T1 HRP20221051T1 (hr) 2023-03-03
HRP20221051T8 true HRP20221051T8 (hr) 2023-07-21

Family

ID=58633036

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20221051TT HRP20221051T8 (hr) 2016-04-15 2017-04-18 Heterociklički spojevi kao inhibitori ret kinaze

Country Status (12)

Country Link
US (3) US10844067B2 (hr)
EP (2) EP3442535B1 (hr)
DK (1) DK3442535T3 (hr)
ES (1) ES2925698T3 (hr)
HR (1) HRP20221051T8 (hr)
HU (1) HUE060082T2 (hr)
LT (1) LT3442535T (hr)
PL (1) PL3442535T3 (hr)
PT (1) PT3442535T (hr)
RS (1) RS63609B1 (hr)
SI (1) SI3442535T1 (hr)
WO (1) WO2017178845A1 (hr)

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Also Published As

Publication number Publication date
LT3442535T (lt) 2022-10-25
RS63609B1 (sr) 2022-10-31
HRP20221051T1 (hr) 2023-03-03
SI3442535T1 (sl) 2023-01-31
EP4104837A2 (en) 2022-12-21
EP4104837A3 (en) 2023-04-26
WO2017178845A1 (en) 2017-10-19
EP3442535A1 (en) 2019-02-20
ES2925698T3 (es) 2022-10-19
HUE060082T2 (hu) 2023-01-28
US20190263819A1 (en) 2019-08-29
PT3442535T (pt) 2022-09-05
US11661423B2 (en) 2023-05-30
EP3442535B1 (en) 2022-06-01
US10844067B2 (en) 2020-11-24
PL3442535T3 (pl) 2022-10-24
US20240116938A1 (en) 2024-04-11
DK3442535T3 (da) 2022-09-05
US20210047334A1 (en) 2021-02-18

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