HRP20210565T1 - Čestice želatina/pektina - Google Patents

Čestice želatina/pektina Download PDF

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Publication number
HRP20210565T1
HRP20210565T1 HRP20210565TT HRP20210565T HRP20210565T1 HR P20210565 T1 HRP20210565 T1 HR P20210565T1 HR P20210565T T HRP20210565T T HR P20210565TT HR P20210565 T HRP20210565 T HR P20210565T HR P20210565 T1 HRP20210565 T1 HR P20210565T1
Authority
HR
Croatia
Prior art keywords
pectin
gelatin
particles according
mixture
aqueous solution
Prior art date
Application number
HRP20210565TT
Other languages
English (en)
Inventor
John M. Dolphin
Michelle A. Montgomery
Original Assignee
Gelita Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gelita Ag filed Critical Gelita Ag
Publication of HRP20210565T1 publication Critical patent/HRP20210565T1/hr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/231Pectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A23L29/281Proteins, e.g. gelatin or collagen
    • A23L29/284Gelatin; Collagen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/20Agglomerating; Granulating; Tabletting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Confectionery (AREA)

Claims (12)

1. Mnoštvo čestica koje se sastoje od (a) vode; (b) pektina; (c) želatine; (d) izborno jednog ili više ugljikohidrata; (e) izborno jedne ili više organskih kiselina ili njihovih soli; i (f) izborno jedne ili više anorganskih soli i veličine od 3.4 mm (6 oka) do 0.4 mm (40 oka), koje se dobivaju postupkom koji obuhvaća: (a) otapanje pektina u vodenoj otopini da bi se dobila vodena otopina otopljenog pektina; (b) miješanje vodene otopine otopljenog pektina s tekućom želatinom da se dobije mješavina želatina/pektin; (c) sušenje mješavine želatina/pektin; i (d) mljevenje mješavine želatina/pektin radi stvaranja mnoštva čestica.
2. Mnoštvo čestica prema zahtjevu 1, naznačeno time što pektin sadrži niski metoksil (LM) pektin, visoki metoksil (HM) pektin, amidirani visoki metoksil pektin, ili amidirani niski metoksil pektin.
3. Mnoštvo čestica prema bilo kojem od zahtjeva 1-2, naznačeno time što želatina ima opseg cvata od 50 do 300, poželjno od 70 do 180.
4. Mnoštvo čestica prema bilo kojem od zahtjeva 1-3, naznačeno time što je pektin prisutan u količini od 1% do 30% po težini (u odnosu na suhu masu), poželjno u količini od 5% do 15% po težini (u odnosu na suhu masu).
5. Mnoštvo čestica prema bilo kojem od zahtjeva 1-4, naznačeno time što je želatina prisutna u količini od 70% do 99% po težini (u odnosu na suhu masu), poželjno u količini od 85% do 95% po težini (u odnosu na suhu masu).
6. Mnoštvo čestica prema bilo kojem od zahtjeva 1-5, naznačeno time što čestica ima veličinu od 3.4 mm (6 oka) do 1.2 mm (16 oka).
7. Mnoštvo čestica prema bilo kojem od zahtjeva 1-6, naznačeno time što čestica nadalje sadrži jedan ili više ugljikohidrata, koji poželjno sadrže jedan ili više maltodekstrina, saharoze, glukoze i maltoze.
8. Mnoštvo čestica prema bilo kojem od zahtjeva 1-7, naznačeno time što se čestica otapa u vodi na ≤60 ° C.
9. Mnoštvo čestica u skladu s bilo kojim od patentnih zahtjeva 1-8, naznačeno time što se čestica otapa u mješavini vode i najmanje jednom plastifikatoru na ≤60 ° C.
10. Mnoštvo čestica prema zahtjevu 9, naznačeno time što je plastifikator glicerol, sorbitol, sorbitan, manitol, ili bilo koja njihova kombinacija.
11. Mnoštvo čestica prema zahtjevu 9 ili 10, naznačeno time što je plastifikator prisutan u količini od 5% do 40% težine ukupne količine mješavine.
12. Postupak stvaranja mnoštva čestica prema bilo kojem od zahtjeva 1 do 11, postupak koji obuhvaća: (a) otapanje pektina u vodenoj otopini da bi se dobila vodena otopina otopljenog pektina; (b) miješanje vodene otopine otopljenog pektina s tekućom želatinom da se dobije mješavina želatina/pektin; (c) sušenje mješavine želatina/pektin; i (d) mljevenje mješavine želatina/pektin radi stvaranja mnoštva čestica.
HRP20210565TT 2014-09-11 2021-04-09 Čestice želatina/pektina HRP20210565T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462049034P 2014-09-11 2014-09-11
PCT/EP2015/066663 WO2016037745A1 (en) 2014-09-11 2015-07-21 Gelatin/pectin particles
EP15749736.3A EP3191083B1 (en) 2014-09-11 2015-07-21 Gelatin/pectin particles

Publications (1)

Publication Number Publication Date
HRP20210565T1 true HRP20210565T1 (hr) 2021-05-14

Family

ID=53835397

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20210565TT HRP20210565T1 (hr) 2014-09-11 2021-04-09 Čestice želatina/pektina

Country Status (14)

Country Link
US (1) US10238603B2 (hr)
EP (1) EP3191083B1 (hr)
JP (2) JP2017528458A (hr)
KR (1) KR102305346B1 (hr)
CN (1) CN107072950B (hr)
AR (1) AR101759A1 (hr)
CO (1) CO2017002367A2 (hr)
DK (1) DK3191083T3 (hr)
ES (1) ES2862134T3 (hr)
HR (1) HRP20210565T1 (hr)
HU (1) HUE053962T2 (hr)
PL (1) PL3191083T3 (hr)
SI (1) SI3191083T1 (hr)
WO (1) WO2016037745A1 (hr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
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CN113559079B (zh) * 2020-04-28 2023-10-20 江苏恒瑞医药股份有限公司 一种软胶囊及其制备方法和用途

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Also Published As

Publication number Publication date
AR101759A1 (es) 2017-01-11
EP3191083A1 (en) 2017-07-19
US10238603B2 (en) 2019-03-26
WO2016037745A1 (en) 2016-03-17
CN107072950A (zh) 2017-08-18
KR102305346B1 (ko) 2021-09-28
EP3191083B1 (en) 2021-03-17
HUE053962T2 (hu) 2021-08-30
SI3191083T1 (sl) 2021-07-30
JP2017528458A (ja) 2017-09-28
CN107072950B (zh) 2020-11-03
CO2017002367A2 (es) 2017-04-28
JP2019206599A (ja) 2019-12-05
BR112017003135A2 (pt) 2017-11-28
US20170151176A1 (en) 2017-06-01
ES2862134T3 (es) 2021-10-07
DK3191083T3 (da) 2021-04-19
PL3191083T3 (pl) 2021-07-12
KR20170051425A (ko) 2017-05-11

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