HRP20090017T3 - 3,11b-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation - Google Patents

3,11b-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation

Info

Publication number
HRP20090017T3
HRP20090017T3 HR20090017T HRP20090017T HRP20090017T3 HR P20090017 T3 HRP20090017 T3 HR P20090017T3 HR 20090017 T HR20090017 T HR 20090017T HR P20090017 T HRP20090017 T HR P20090017T HR P20090017 T3 HRP20090017 T3 HR P20090017T3
Authority
HR
Croatia
Prior art keywords
cis
treatment
dihydrotetrabenazine
inflammation
proliferative disease
Prior art date
Application number
HR20090017T
Other languages
English (en)
Croatian (hr)
Inventor
John Duffield Andrew
Elisabeth Yarrow Jean
Original Assignee
Cambridge Laboratories (Ireland) Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Laboratories (Ireland) Limited filed Critical Cambridge Laboratories (Ireland) Limited
Publication of HRP20090017T3 publication Critical patent/HRP20090017T3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
HR20090017T 2005-08-05 2009-01-14 3,11b-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation HRP20090017T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0516168.2A GB0516168D0 (en) 2005-08-05 2005-08-05 Pharmaceutical compounds
PCT/GB2006/002909 WO2007017643A1 (en) 2005-08-05 2006-08-04 3 , llB-CIS-DIHYDROTETRABENAZINE FOR THE TREATMENT OF A PROLIFERATIVE DISEASE OR AN INFLAMMATION

Publications (1)

Publication Number Publication Date
HRP20090017T3 true HRP20090017T3 (en) 2009-03-31

Family

ID=34984180

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20090017T HRP20090017T3 (en) 2005-08-05 2009-01-14 3,11b-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation

Country Status (24)

Country Link
US (1) US20090275605A1 (xx)
EP (2) EP1964565A1 (xx)
JP (1) JP2009503045A (xx)
KR (1) KR20080033501A (xx)
CN (1) CN101321528B (xx)
AT (1) ATE412414T1 (xx)
AU (1) AU2006277836B8 (xx)
CA (1) CA2620952A1 (xx)
CY (1) CY1108729T1 (xx)
DE (1) DE602006003415D1 (xx)
DK (1) DK1861100T3 (xx)
ES (1) ES2317564T3 (xx)
GB (1) GB0516168D0 (xx)
HK (1) HK1111084A1 (xx)
HR (1) HRP20090017T3 (xx)
MX (1) MX2008001546A (xx)
NZ (1) NZ566010A (xx)
PL (1) PL1861100T3 (xx)
PT (1) PT1861100E (xx)
RS (1) RS50720B (xx)
RU (1) RU2409364C2 (xx)
SI (1) SI1861100T1 (xx)
WO (1) WO2007017643A1 (xx)
ZA (2) ZA200801171B (xx)

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GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US8039627B2 (en) 2006-11-08 2011-10-18 Neurocrine Biosciences, Inc. Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto
GB0721669D0 (en) * 2007-11-02 2007-12-12 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
CN103003275A (zh) 2010-06-01 2013-03-27 奥斯拜客斯制药有限公司 Vmat2的苯并喹啉酮抑制剂
CN102285984B (zh) * 2010-11-25 2012-10-10 江苏威凯尔医药科技有限公司 (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法
AU2015209330A1 (en) 2014-01-27 2016-07-28 Auspex Pharmaceuticals, Inc. Benzoquinoline inhibitors of vesicular monoamine transporter 2
MA41177A (fr) * 2014-12-15 2017-10-24 Esteve Labor Dr Utilisation de ligands des récepteurs sigma dans l'arthrose
WO2017164407A1 (ja) * 2016-03-25 2017-09-28 国立大学法人東北大学 免疫チェックポイント阻害作用を有するインドールアルカロイド型化合物
CN109283263B (zh) * 2017-07-21 2019-06-25 南京正大天晴制药有限公司 用于雷替曲塞合成质量控制的检测分析方法
CN109283279B (zh) * 2017-07-21 2019-11-01 南京正大天晴制药有限公司 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法

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US3009918A (en) * 1961-11-21 Chz ch
US2843591A (en) * 1958-07-15 Method for preparing same
US3079395A (en) * 1963-02-26 Novel z-oxq-benzoquinoliaine
US3053845A (en) * 1962-09-11 Benzofykedocolines
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GB999092A (en) * 1959-11-24 1965-07-21 Wellcome Found Method for making benzo(a)-quinolizine derivatives
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GB1513824A (en) * 1975-05-22 1978-06-14 Wyeth John & Brother Ltd 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative
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GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma

Also Published As

Publication number Publication date
EP1964565A1 (en) 2008-09-03
ES2317564T3 (es) 2009-04-16
ZA200801171B (en) 2009-08-26
RS50720B (sr) 2010-08-31
GB0516168D0 (en) 2005-09-14
HK1111084A1 (en) 2008-08-01
RU2409364C2 (ru) 2011-01-20
AU2006277836B8 (en) 2011-12-08
JP2009503045A (ja) 2009-01-29
KR20080033501A (ko) 2008-04-16
MX2008001546A (es) 2008-04-04
ZA200801170B (en) 2009-12-30
CY1108729T1 (el) 2014-04-09
DE602006003415D1 (de) 2008-12-11
AU2006277836A1 (en) 2007-02-15
WO2007017643A1 (en) 2007-02-15
EP1861100A1 (en) 2007-12-05
PL1861100T3 (pl) 2009-06-30
DK1861100T3 (da) 2008-12-15
US20090275605A1 (en) 2009-11-05
ATE412414T1 (de) 2008-11-15
PT1861100E (pt) 2008-12-26
CA2620952A1 (en) 2007-02-15
EP1861100B1 (en) 2008-10-29
NZ566010A (en) 2010-05-28
RU2008108516A (ru) 2009-09-10
CN101321528B (zh) 2011-05-25
SI1861100T1 (sl) 2009-04-30
CN101321528A (zh) 2008-12-10
AU2006277836B2 (en) 2011-11-10

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