HRP20080367T3 - Use of methylene amide derivatives in cardiovascular disorders - Google Patents

Use of methylene amide derivatives in cardiovascular disorders

Info

Publication number
HRP20080367T3
HRP20080367T3 HR20080367T HRP20080367T HRP20080367T3 HR P20080367 T3 HRP20080367 T3 HR P20080367T3 HR 20080367 T HR20080367 T HR 20080367T HR P20080367 T HRP20080367 T HR P20080367T HR P20080367 T3 HRP20080367 T3 HR P20080367T3
Authority
HR
Croatia
Prior art keywords
amide derivatives
cardiovascular disorders
methylene amide
prevention
formula
Prior art date
Application number
HR20080367T
Other languages
English (en)
Croatian (hr)
Inventor
Hooft Van Huijsduijnen Rob
Richard Vincent
Original Assignee
Laboratoires Serono S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Serono S.A. filed Critical Laboratoires Serono S.A.
Publication of HRP20080367T3 publication Critical patent/HRP20080367T3/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HR20080367T 2004-02-27 2008-07-24 Use of methylene amide derivatives in cardiovascular disorders HRP20080367T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04100778 2004-02-27
PCT/EP2005/050823 WO2005082347A1 (en) 2004-02-27 2005-02-25 Use of methylene amide derivatives in cardiovascular disorders

Publications (1)

Publication Number Publication Date
HRP20080367T3 true HRP20080367T3 (en) 2008-09-30

Family

ID=34896106

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20080367T HRP20080367T3 (en) 2004-02-27 2008-07-24 Use of methylene amide derivatives in cardiovascular disorders

Country Status (24)

Country Link
US (1) US20070185118A1 (pt)
EP (1) EP1732534B1 (pt)
JP (1) JP5001138B2 (pt)
KR (1) KR101188940B1 (pt)
CN (1) CN1933827B (pt)
AT (1) ATE401877T1 (pt)
AU (1) AU2005216649B2 (pt)
BR (1) BRPI0508080A (pt)
CA (1) CA2554919C (pt)
CY (1) CY1108252T1 (pt)
DE (1) DE602005008412D1 (pt)
DK (1) DK1732534T3 (pt)
EA (1) EA011811B1 (pt)
ES (1) ES2308458T3 (pt)
HK (1) HK1098073A1 (pt)
HR (1) HRP20080367T3 (pt)
IL (1) IL177494A (pt)
NO (1) NO20064295L (pt)
PL (1) PL1732534T3 (pt)
PT (1) PT1732534E (pt)
RS (1) RS50596B (pt)
SI (1) SI1732534T1 (pt)
UA (1) UA84453C2 (pt)
WO (1) WO2005082347A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA012260B1 (ru) * 2002-01-29 2009-08-28 Лаборатуар Сероно Са ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ МЕТИЛЕНАМИДА В КАЧЕСТВЕ МОДУЛЯТОРОВ ПРОТЕИНТИРОЗИНФОСФАТАЗ (PTPs)
CA2527861A1 (en) 2003-07-21 2005-02-10 Applied Research Systems Ars Holding N.V. Alkynyl aryl carboxamides
AU2007307599A1 (en) 2006-10-12 2008-04-17 Institute Of Medicinal Molecular Design. Inc. N-phenyloxamic acid derivatives
US8633245B2 (en) * 2008-04-11 2014-01-21 Institute Of Medicinal Molecular Design, Inc. PAI-1 inhibitor
JP2014525501A (ja) 2011-08-29 2014-09-29 ティコナ・エルエルシー 高流動性液晶ポリマー組成物
US9096794B2 (en) 2011-08-29 2015-08-04 Ticona Llc High flow liquid crystalline polymer composition
WO2013032975A1 (en) 2011-08-29 2013-03-07 Ticona Llc Thermotropic liquid crystalline polymer with improved low shear viscosity
WO2013032977A1 (en) 2011-08-29 2013-03-07 Ticona Llc Heat-resistant liquid crystalline polymer composition having a low melting temperature
WO2013032967A1 (en) 2011-08-29 2013-03-07 Ticona Llc Cast molded parts formed form a liquid crystalline polymer
JP2014525500A (ja) 2011-08-29 2014-09-29 ティコナ・エルエルシー 低溶融粘度液晶ポリマーの溶融重合
JP2014529627A (ja) 2011-08-29 2014-11-13 ティコナ・エルエルシー 芳香族アミド化合物
US8852730B2 (en) 2011-08-29 2014-10-07 Ticona Llc Melt-extruded substrate for use in thermoformed articles
US8669341B2 (en) 2011-08-29 2014-03-11 Ticona Llc Solid-state polymerization of a liquid crystalline polymer
US20150337212A1 (en) 2012-12-17 2015-11-26 Shell Oil Company Integrated gas-to-liquids condensate process
WO2014130275A2 (en) 2013-02-22 2014-08-28 Ticona Llc High performance polymer composition with improved flow properties
US9206300B2 (en) 2013-06-07 2015-12-08 Ticona Llc High strength thermotropic liquid crystalline polymer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6985200A (en) * 1999-09-10 2001-04-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
US6627767B2 (en) * 2000-08-29 2003-09-30 Abbott Laboratories Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors
DE10117823A1 (de) * 2001-04-10 2002-10-17 Merck Patent Gmbh Oxalsäurederivate
WO2002098408A1 (en) * 2001-06-07 2002-12-12 Wyeth Ptpase inhibitors for improving cardiovascular risk profile
AR034374A1 (es) * 2001-06-07 2004-02-18 Wyeth Corp Combinacion de un inhibidor de ptpasa y un inhibidor de ace
EA012260B1 (ru) * 2002-01-29 2009-08-28 Лаборатуар Сероно Са ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ МЕТИЛЕНАМИДА В КАЧЕСТВЕ МОДУЛЯТОРОВ ПРОТЕИНТИРОЗИНФОСФАТАЗ (PTPs)

Also Published As

Publication number Publication date
EP1732534A1 (en) 2006-12-20
PT1732534E (pt) 2008-08-08
HK1098073A1 (en) 2007-07-13
IL177494A (en) 2011-06-30
IL177494A0 (en) 2006-12-31
EA011811B1 (ru) 2009-06-30
NO20064295L (no) 2006-09-22
EP1732534B1 (en) 2008-07-23
EA200601511A1 (ru) 2007-02-27
RS50596B (sr) 2010-05-07
PL1732534T3 (pl) 2008-12-31
ATE401877T1 (de) 2008-08-15
WO2005082347A1 (en) 2005-09-09
CA2554919A1 (en) 2005-09-09
DE602005008412D1 (de) 2008-09-04
AU2005216649A1 (en) 2005-09-09
US20070185118A1 (en) 2007-08-09
AU2005216649B2 (en) 2010-09-09
UA84453C2 (ru) 2008-10-27
DK1732534T3 (da) 2008-11-17
JP5001138B2 (ja) 2012-08-15
CN1933827A (zh) 2007-03-21
CN1933827B (zh) 2011-07-27
CA2554919C (en) 2013-04-16
CY1108252T1 (el) 2014-02-12
SI1732534T1 (sl) 2008-10-31
KR20060129066A (ko) 2006-12-14
BRPI0508080A (pt) 2007-07-17
KR101188940B1 (ko) 2012-10-08
ES2308458T3 (es) 2008-12-01
JP2007524701A (ja) 2007-08-30

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