HRP20070429T3 - Crystal form of asenapine maleate - Google Patents

Crystal form of asenapine maleate

Info

Publication number: HRP20070429T3
Authority: HR; Croatia
Prior art keywords: crystal form; asenapine maleate; asenapine; maleate; oxepino
Prior art date: 2005-04-07

Application number

HR20070429T

Other languages

English (en)

Croatian (hr)

Inventor

Johannes Heeres Gerhardus

Original Assignee

N.V. Organon

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-07

Filing date

2007-09-19

Publication date

2007-11-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36617328&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20070429(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-09-19 Application filed by N.V. Organon filed Critical N.V. Organon

2007-11-30 Publication of HRP20070429T3 publication Critical patent/HRP20070429T3/xx

Links

GMDCDXMAFMEDAG-CHHFXETESA-N (S,S)-asenapine maleate Chemical compound OC(=O)\C=C/C(O)=O.O1C2=CC=CC=C2[C@H]2CN(C)C[C@@H]2C2=CC(Cl)=CC=C21 GMDCDXMAFMEDAG-CHHFXETESA-N 0.000 title 1
229960001615 asenapine maleate Drugs 0.000 title 1
239000013078 crystal Substances 0.000 title 1
VSWBSWWIRNCQIJ-HUUCEWRRSA-N (S,S)-asenapine Chemical compound O1C2=CC=CC=C2[C@H]2CN(C)C[C@@H]2C2=CC(Cl)=CC=C21 VSWBSWWIRNCQIJ-HUUCEWRRSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Hydrogenated Pyridines (AREA)

HR20070429T 2005-04-07 2007-09-19 Crystal form of asenapine maleate HRP20070429T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP05102742		2005-04-07
EP05102969		2005-04-14

Publications (1)

Publication Number	Publication Date
HRP20070429T3 true HRP20070429T3 (en)	2007-11-30

Family

ID=36617328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20070429T HRP20070429T3 (en)	2005-04-07	2007-09-19	Crystal form of asenapine maleate

Country Status (31)

Country	Link
EP (2)	EP1917267B1 (da)
JP (1)	JP5058151B2 (da)
KR (1)	KR101422843B1 (da)
AR (1)	AR056306A1 (da)
AT (2)	ATE370954T1 (da)
AU (1)	AU2006231617B2 (da)
BR (1)	BRPI0609741A8 (da)
CA (1)	CA2603509C (da)
CY (2)	CY1106902T1 (da)
DE (2)	DE602006000080T2 (da)
DK (2)	DK1710245T3 (da)
DO (1)	DOP2006000082A (da)
ES (2)	ES2293626T3 (da)
GT (1)	GT200600135A (da)
HN (1)	HN2006014095A (da)
HR (1)	HRP20070429T3 (da)
IL (1)	IL186355A (da)
MX (1)	MX2007012445A (da)
MY (1)	MY137969A (da)
NO (1)	NO340520B1 (da)
NZ (1)	NZ562124A (da)
PE (1)	PE20061311A1 (da)
PL (2)	PL1917267T3 (da)
PT (2)	PT1710245E (da)
RS (1)	RS50532B (da)
RU (1)	RU2405786C2 (da)
SI (2)	SI1917267T1 (da)
SV (1)	SV2006002473A (da)
TW (1)	TWI364423B (da)
UY (1)	UY29459A1 (da)
WO (1)	WO2006106135A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200831514A (en) *	2006-10-06	2008-08-01	Organon Nv	Amorphous asenapine and processes for preparing same
MX2012000061A (es) *	2009-06-24	2012-06-01	Msd Oss Bv	Formulaciones inyectables que contienen asenapina, y metodo de tratamiento usando las mismas.
EP2582704A4 (en) *	2010-06-18	2014-04-02	Reddys Lab Ltd Dr	Asenapine MALEATE
WO2012066565A2 (en) *	2010-11-16	2012-05-24	Cadila Healthcare Limited	Asenapine maleate amorphous and crystalline form and process for preparation thereof
EP2468750A1 (en)	2010-12-13	2012-06-27	Chemo Ibérica, S.A.	Polymorphic forms of asenapine maleate and processes for their preparation
WO2012123325A1 (en)	2011-03-11	2012-09-20	Medichem S.A.	NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID
ITMI20110734A1 (it) *	2011-05-02	2012-11-03	Olon Spa	Sali cristallini di asenapina
EP2524921A1 (en)	2011-05-17	2012-11-21	Sandoz AG	Novel Crystalline Salts of Asenapine
EP2524920A1 (en)	2011-05-17	2012-11-21	Sandoz AG	Novel Crystalline Asenapine Hydrochloride Salt Forms
EP2524919A1 (en)	2011-05-17	2012-11-21	Sandoz AG	Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids
JP6014656B2 (ja) *	2011-05-18	2016-10-25	ラビラトリオスレスビエスエレ	化合物の多形体
WO2012156676A1 (en) *	2011-05-18	2012-11-22	Laboratorios Lesvi S.L.	Monoclinic crystalline form of asenapine maleate with a specific particle size distribution
EP2572703A1 (en)	2011-09-21	2013-03-27	Hexal AG	Compressed oral dosage form for asenapine maleate
WO2013041604A1 (en)	2011-09-21	2013-03-28	Sandoz Ag	Crystal form of asenapine maleate
CN104487072B (zh) *	2012-07-26	2017-08-04	久光制药株式会社	贴附剂及其制造方法
ITMI20121810A1 (it)	2012-10-24	2014-04-25	Chemo Iberica Sa	Poliformi di maleato di asenapina e processo per la loro preparazione
US9597291B2 (en)	2012-12-11	2017-03-21	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Orally disintegrating tablet containing asenapine
WO2014127786A1 (en)	2013-02-22	2014-08-28	Zentiva, K.S.	Orally disintegrating pharmaceutical composition comprising asenapine
WO2017037718A1 (en)	2015-09-02	2017-03-09	Eloxx Pharmaceuticals Ltd.	Aminoglycoside derivatives and uses thereof in treating genetic disorders
CN115813888A (zh)	2016-12-20	2023-03-21	罗曼治疗***股份公司	包含阿塞那平的透皮治疗***
AU2017384392B2 (en)	2016-12-20	2023-05-25	Lts Lohmann Therapie-Systeme Ag	Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene
BR112019027037B1 (pt)	2017-06-26	2022-04-05	Lts Lohmann Therapie-Systeme Ag	Sistema terapêutico transdérmico contendo asenapina e polímero híbrido acrílico de silicone, e processo para fabricar uma camada contendo asenapina para uso no referido sistema
CN110958876B (zh)	2018-06-20	2020-12-18	罗曼治疗***股份公司	含有阿塞那平的透皮治疗***

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7605526A (nl) *	1976-05-24	1977-11-28	Akzo Nv	Nieuwe tetracyclische derivaten.
DE122010000050I2 (de) *	1994-03-02	2011-07-21	Organon Nv	Sublinguales oder bukkales arzneimittel.
WO1999032108A1 (en) *	1997-12-19	1999-07-01	Akzo Nobel N.V.	Org-5222 in the treatment of depression
TWI327915B (en) *	2003-06-12	2010-08-01	Organon Nv	Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight

2006
- 2006-04-06 MY MYPI20061554A patent/MY137969A/en unknown
- 2006-04-06 JP JP2008504776A patent/JP5058151B2/ja active Active
- 2006-04-06 RS RSP-2007/0436A patent/RS50532B/sr unknown
- 2006-04-06 DO DO2006P000082A patent/DOP2006000082A/es unknown
- 2006-04-06 PE PE2006000377A patent/PE20061311A1/es active IP Right Grant
- 2006-04-06 HN HN2006014095A patent/HN2006014095A/es unknown
- 2006-04-06 RU RU2007141198/04A patent/RU2405786C2/ru active Protection Beyond IP Right Term
- 2006-04-06 PL PL06725622T patent/PL1917267T3/pl unknown
- 2006-04-06 EP EP06725622A patent/EP1917267B1/en active Active
- 2006-04-06 WO PCT/EP2006/061408 patent/WO2006106135A1/en active Application Filing
- 2006-04-06 AU AU2006231617A patent/AU2006231617B2/en active Active
- 2006-04-06 DE DE602006000080T patent/DE602006000080T2/de active Active
- 2006-04-06 PL PL06112332T patent/PL1710245T3/pl unknown
- 2006-04-06 AR ARP060101358A patent/AR056306A1/es not_active Application Discontinuation
- 2006-04-06 EP EP06112332A patent/EP1710245B1/en active Active
- 2006-04-06 CA CA2603509A patent/CA2603509C/en active Active
- 2006-04-06 KR KR1020077025428A patent/KR101422843B1/ko active IP Right Grant
- 2006-04-06 SI SI200630190T patent/SI1917267T1/sl unknown
- 2006-04-06 BR BRPI0609741A patent/BRPI0609741A8/pt not_active IP Right Cessation
- 2006-04-06 AT AT06112332T patent/ATE370954T1/de active
- 2006-04-06 DK DK06112332T patent/DK1710245T3/da active
- 2006-04-06 AT AT06725622T patent/ATE418556T1/de active
- 2006-04-06 ES ES06112332T patent/ES2293626T3/es active Active
- 2006-04-06 DE DE602006004463T patent/DE602006004463D1/de active Active
- 2006-04-06 SV SV2006002473A patent/SV2006002473A/es unknown
- 2006-04-06 PT PT06112332T patent/PT1710245E/pt unknown
- 2006-04-06 GT GT200600135A patent/GT200600135A/es unknown
- 2006-04-06 SI SI200630006T patent/SI1710245T1/sl unknown
- 2006-04-06 UY UY29459A patent/UY29459A1/es not_active Application Discontinuation
- 2006-04-06 ES ES06725622T patent/ES2318742T3/es active Active
- 2006-04-06 TW TW095112187A patent/TWI364423B/zh active
- 2006-04-06 DK DK06725622T patent/DK1917267T3/da active
- 2006-04-06 NZ NZ562124A patent/NZ562124A/en unknown
- 2006-04-06 MX MX2007012445A patent/MX2007012445A/es active IP Right Grant
- 2006-04-06 PT PT06725622T patent/PT1917267E/pt unknown
2007
- 2007-09-19 HR HR20070429T patent/HRP20070429T3/xx unknown
- 2007-10-02 CY CY20071101258T patent/CY1106902T1/el unknown
- 2007-10-07 IL IL186355A patent/IL186355A/en active IP Right Grant
- 2007-10-10 NO NO20075142A patent/NO340520B1/no unknown
2009
- 2009-01-30 CY CY20091100111T patent/CY1108742T1/el unknown

Also Published As

Publication number	Publication date
CY1106902T1 (el)	2012-09-26
PE20061311A1 (es)	2007-02-09
BRPI0609741A8 (pt)	2018-03-13
AR056306A1 (es)	2007-10-03
HN2006014095A (es)	2010-08-19
RU2405786C2 (ru)	2010-12-10
UY29459A1 (es)	2006-11-30
ATE370954T1 (de)	2007-09-15
JP2008534656A (ja)	2008-08-28
BRPI0609741A2 (pt)	2010-04-27
SI1710245T1 (sl)	2007-12-31
RS50532B (sr)	2010-05-07
ES2318742T3 (es)	2009-05-01
RU2007141198A (ru)	2009-05-20
MX2007012445A (es)	2007-11-07
NO20075142L (no)	2007-11-05
DE602006000080D1 (de)	2007-10-04
NZ562124A (en)	2010-07-30
DK1710245T3 (da)	2007-12-03
TWI364423B (en)	2012-05-21
MY137969A (en)	2009-04-30
PL1917267T3 (pl)	2009-06-30
DK1917267T3 (da)	2009-04-14
DE602006000080T2 (de)	2008-05-15
CY1108742T1 (el)	2014-04-09
SV2006002473A (es)	2009-11-24
JP5058151B2 (ja)	2012-10-24
DE602006004463D1 (de)	2009-02-05
CA2603509A1 (en)	2006-10-12
EP1917267B1 (en)	2008-12-24
KR101422843B1 (ko)	2014-07-24
KR20080005253A (ko)	2008-01-10
AU2006231617A1 (en)	2006-10-12
DOP2006000082A (es)	2006-11-30
IL186355A0 (en)	2008-01-20
SI1917267T1 (sl)	2009-04-30
CA2603509C (en)	2013-12-03
PT1917267E (pt)	2009-02-04
NO340520B1 (no)	2017-05-02
PT1710245E (pt)	2007-10-03
WO2006106135A1 (en)	2006-10-12
PL1710245T3 (pl)	2008-01-31
IL186355A (en)	2016-05-31
EP1710245B1 (en)	2007-08-22
EP1917267A1 (en)	2008-05-07
ATE418556T1 (de)	2009-01-15
EP1710245A1 (en)	2006-10-11
GT200600135A (es)	2006-11-07
TW200722428A (en)	2007-06-16
AU2006231617B2 (en)	2010-06-03
ES2293626T3 (es)	2008-03-16

Publication	Publication Date	Title
HRP20070429T3 (en)	2007-11-30	Crystal form of asenapine maleate
UA93044C2 (en)	2011-01-10	urn:schemas-microsoft-com:office:smarttagsCRYSTALFORM OF ASENAPINE MALEATE
IN2012DN02610A (da)	2015-09-04
WO2007015017A3 (fr)	2007-05-10	Nouveaux derives de polyquinoleines et leur utilisation therapeutique
TW200613256A (en)	2006-05-01	Photoactive compounds
SG145694A1 (en)	2008-09-29	Novel compounds
TW200617019A (en)	2006-06-01	A process for the preparation of 7α-alkylated 19-norsteroids
WO2005037198A3 (en)	2005-06-09	Preparation of 1,7-disubstituted azabenzimidazoles as kinase inhibitors
WO2007000325A3 (de)	2007-04-19	Substituierte 1-oxa-3,8-diazaspiro[4.5]-decan-2-on-verbindungen und deren verwendung zur herstellung von arzneimitteln
ATE516291T1 (de)	2011-07-15	Thenopyrimidin-verbindungen mit fungizider aktivität
DK1753776T3 (da)	2009-05-11	Camptotheciner, som er konjugeret i 7-stillingen til cykliske peptider, som cytostatiske midler
MX2007004591A (es)	2007-06-25	Proceso para la preparacion de compuestos organicos.
GB0324210D0 (en)	2003-11-19	Organic compounds
HK1094575A1 (en)	2007-04-04	A process for the preparation of phenyltetrazole derivatives
DK1501838T3 (da)	2007-08-20	Fremgangsmåde til fremstilling af clopidogrel
TW200606166A (en)	2006-02-16	Compounds containing 3,4-methylenedioxythiophene units
IL182575A0 (en)	2007-07-24	On-resin peptide cyclization
AU2003288173A1 (en)	2004-06-18	Safety element exhibiting properties activable by energy supply
HU0402571D0 (en)	2005-02-28	Corn-growing by trench cultivation
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GB0514615D0 (en)	2005-08-24	Organic compounds
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ZA200407913B (en)	2005-10-06	Polycyclic compounds as potent alpha2-adrenoceptorantagonists.
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