HN2006014095A - Forma cristalina ortorrombica del maleato de asenapina - Google Patents
Forma cristalina ortorrombica del maleato de asenapinaInfo
- Publication number
- HN2006014095A HN2006014095A HN2006014095A HN2006014095A HN2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A
- Authority
- HN
- Honduras
- Prior art keywords
- orthromby
- crystal form
- asenapine maleate
- asenapine
- maleate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Abstract
La invencion se refiere a una nueva forma cristalina de asenapina, a metodos para su preparacion y a composiciones farmaceuticas que comprenden dicha forma cristalina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05102742 | 2005-04-07 | ||
EP05102969 | 2005-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
HN2006014095A true HN2006014095A (es) | 2010-08-19 |
Family
ID=36617328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HN2006014095A HN2006014095A (es) | 2005-04-07 | 2006-04-06 | Forma cristalina ortorrombica del maleato de asenapina |
Country Status (31)
Country | Link |
---|---|
EP (2) | EP1917267B1 (es) |
JP (1) | JP5058151B2 (es) |
KR (1) | KR101422843B1 (es) |
AR (1) | AR056306A1 (es) |
AT (2) | ATE418556T1 (es) |
AU (1) | AU2006231617B2 (es) |
BR (1) | BRPI0609741A8 (es) |
CA (1) | CA2603509C (es) |
CY (2) | CY1106902T1 (es) |
DE (2) | DE602006004463D1 (es) |
DK (2) | DK1710245T3 (es) |
DO (1) | DOP2006000082A (es) |
ES (2) | ES2293626T3 (es) |
GT (1) | GT200600135A (es) |
HN (1) | HN2006014095A (es) |
HR (1) | HRP20070429T3 (es) |
IL (1) | IL186355A (es) |
MX (1) | MX2007012445A (es) |
MY (1) | MY137969A (es) |
NO (1) | NO340520B1 (es) |
NZ (1) | NZ562124A (es) |
PE (1) | PE20061311A1 (es) |
PL (2) | PL1917267T3 (es) |
PT (2) | PT1710245E (es) |
RS (1) | RS50532B (es) |
RU (1) | RU2405786C2 (es) |
SI (2) | SI1710245T1 (es) |
SV (1) | SV2006002473A (es) |
TW (1) | TWI364423B (es) |
UY (1) | UY29459A1 (es) |
WO (1) | WO2006106135A1 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2007002891A1 (es) * | 2006-10-06 | 2008-04-18 | Organon Nv | Trans-5-cloro-2-metil-2,3,3a,12b-tetrahidro-1h-dibenz-[2,3:6,7]oxepino[4,5-c]pirrol 50% amorfo en base al peso total del compuesto; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento de un trastorno seleccionado entre e |
AU2010264670A1 (en) * | 2009-06-24 | 2012-01-19 | Merck Sharp & Dohme B.V. | Injectable formulations containing asenapine and method of treatment using same |
WO2011159903A2 (en) | 2010-06-18 | 2011-12-22 | Dr. Reddy's Laboratories Ltd. | Asenapine maleate |
WO2012066565A2 (en) * | 2010-11-16 | 2012-05-24 | Cadila Healthcare Limited | Asenapine maleate amorphous and crystalline form and process for preparation thereof |
EP2468750A1 (en) | 2010-12-13 | 2012-06-27 | Chemo Ibérica, S.A. | Polymorphic forms of asenapine maleate and processes for their preparation |
WO2012123325A1 (en) | 2011-03-11 | 2012-09-20 | Medichem S.A. | NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID |
ITMI20110734A1 (it) * | 2011-05-02 | 2012-11-03 | Olon Spa | Sali cristallini di asenapina |
EP2524920A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Asenapine Hydrochloride Salt Forms |
EP2524919A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids |
EP2524921A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Salts of Asenapine |
WO2012156676A1 (en) * | 2011-05-18 | 2012-11-22 | Laboratorios Lesvi S.L. | Monoclinic crystalline form of asenapine maleate with a specific particle size distribution |
US9505771B2 (en) | 2011-05-18 | 2016-11-29 | Laboratories Lesvi S.L. | Stable micronised monoclin form of asenapine maleate and its synthesis |
EP2572703A1 (en) | 2011-09-21 | 2013-03-27 | Hexal AG | Compressed oral dosage form for asenapine maleate |
WO2013041604A1 (en) | 2011-09-21 | 2013-03-28 | Sandoz Ag | Crystal form of asenapine maleate |
ES2632946T3 (es) * | 2012-07-26 | 2017-09-18 | Hisamitsu Pharmaceutical Co., Inc. | Parche |
ITMI20121810A1 (it) | 2012-10-24 | 2014-04-25 | Chemo Iberica Sa | Poliformi di maleato di asenapina e processo per la loro preparazione |
US9597291B2 (en) | 2012-12-11 | 2017-03-21 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Orally disintegrating tablet containing asenapine |
WO2014127786A1 (en) | 2013-02-22 | 2014-08-28 | Zentiva, K.S. | Orally disintegrating pharmaceutical composition comprising asenapine |
EP3350194A4 (en) | 2015-09-02 | 2019-04-24 | Eloxx Pharmaceuticals Ltd. | AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES |
CN110087641B (zh) | 2016-12-20 | 2024-03-12 | 罗曼治疗***股份公司 | 含有阿塞那平和聚硅氧烷或聚异丁烯的透皮治疗*** |
MX2019007391A (es) | 2016-12-20 | 2019-08-16 | Lts Lohmann Therapie Systeme Ag | Sistema terapeutico transdermico que contiene asenapina. |
CN110799180A (zh) | 2017-06-26 | 2020-02-14 | 罗曼治疗***股份公司 | 含阿塞那平和硅氧烷丙烯酸杂化聚合物的经皮治疗*** |
WO2019243452A1 (en) | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
CZ284633B6 (cs) * | 1994-03-02 | 1999-01-13 | Akzo Nobel N. V. | Farmaceutický prostředek a použití trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrolu pro výrobu farmaceutického prostředku |
AU2418499A (en) * | 1997-12-19 | 1999-07-12 | Akzo Nobel N.V. | Org-5222 in the treatment of depression |
TWI327915B (en) * | 2003-06-12 | 2010-08-01 | Organon Nv | Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight |
-
2006
- 2006-04-06 PT PT06112332T patent/PT1710245E/pt unknown
- 2006-04-06 DK DK06112332T patent/DK1710245T3/da active
- 2006-04-06 ES ES06112332T patent/ES2293626T3/es active Active
- 2006-04-06 PL PL06725622T patent/PL1917267T3/pl unknown
- 2006-04-06 ES ES06725622T patent/ES2318742T3/es active Active
- 2006-04-06 AT AT06725622T patent/ATE418556T1/de active
- 2006-04-06 SV SV2006002473A patent/SV2006002473A/es unknown
- 2006-04-06 CA CA2603509A patent/CA2603509C/en active Active
- 2006-04-06 BR BRPI0609741A patent/BRPI0609741A8/pt not_active IP Right Cessation
- 2006-04-06 PT PT06725622T patent/PT1917267E/pt unknown
- 2006-04-06 AR ARP060101358A patent/AR056306A1/es not_active Application Discontinuation
- 2006-04-06 EP EP06725622A patent/EP1917267B1/en active Active
- 2006-04-06 DE DE602006004463T patent/DE602006004463D1/de active Active
- 2006-04-06 NZ NZ562124A patent/NZ562124A/en unknown
- 2006-04-06 RU RU2007141198/04A patent/RU2405786C2/ru active Protection Beyond IP Right Term
- 2006-04-06 KR KR1020077025428A patent/KR101422843B1/ko active IP Right Grant
- 2006-04-06 DK DK06725622T patent/DK1917267T3/da active
- 2006-04-06 DE DE602006000080T patent/DE602006000080T2/de active Active
- 2006-04-06 RS RSP-2007/0436A patent/RS50532B/sr unknown
- 2006-04-06 MX MX2007012445A patent/MX2007012445A/es active IP Right Grant
- 2006-04-06 JP JP2008504776A patent/JP5058151B2/ja active Active
- 2006-04-06 AT AT06112332T patent/ATE370954T1/de active
- 2006-04-06 PE PE2006000377A patent/PE20061311A1/es active IP Right Grant
- 2006-04-06 MY MYPI20061554A patent/MY137969A/en unknown
- 2006-04-06 GT GT200600135A patent/GT200600135A/es unknown
- 2006-04-06 SI SI200630006T patent/SI1710245T1/sl unknown
- 2006-04-06 PL PL06112332T patent/PL1710245T3/pl unknown
- 2006-04-06 SI SI200630190T patent/SI1917267T1/sl unknown
- 2006-04-06 EP EP06112332A patent/EP1710245B1/en active Active
- 2006-04-06 HN HN2006014095A patent/HN2006014095A/es unknown
- 2006-04-06 TW TW095112187A patent/TWI364423B/zh active
- 2006-04-06 AU AU2006231617A patent/AU2006231617B2/en active Active
- 2006-04-06 UY UY29459A patent/UY29459A1/es not_active Application Discontinuation
- 2006-04-06 DO DO2006P000082A patent/DOP2006000082A/es unknown
- 2006-04-06 WO PCT/EP2006/061408 patent/WO2006106135A1/en active Application Filing
-
2007
- 2007-09-19 HR HR20070429T patent/HRP20070429T3/xx unknown
- 2007-10-02 CY CY20071101258T patent/CY1106902T1/el unknown
- 2007-10-07 IL IL186355A patent/IL186355A/en active IP Right Grant
- 2007-10-10 NO NO20075142A patent/NO340520B1/no unknown
-
2009
- 2009-01-30 CY CY20091100111T patent/CY1108742T1/el unknown
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