HRP20030870B1 - Aripiprazole oral solution - Google Patents

Aripiprazole oral solution

Info

Publication number: HRP20030870B1
Authority: HR; Croatia
Prior art keywords: acid; oral solution; aripiprazole; solution; aripiprazole oral
Prior art date: 2001-04-25

Application number

HR20030870A

Other languages

English (en)

Croatian (hr)

Inventor

Parab Prakash

Chou Joyce

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-25

Filing date

2003-10-24

Publication date

2011-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23099862&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20030870(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-10-24 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2004-06-30 Publication of HRP20030870A2 publication Critical patent/HRP20030870A2/hr

2011-10-31 Publication of HRP20030870B1 publication Critical patent/HRP20030870B1/xx

Links

229940072100 aripiprazole oral solution Drugs 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
CEUORZQYGODEFX-UHFFFAOYSA-N Aripirazole Chemical compound ClC1=CC=CC(N2CCN(CCCCOC=3C=C4NC(=O)CCC4=CC=3)CC2)=C1Cl CEUORZQYGODEFX-UHFFFAOYSA-N 0.000 abstract 1
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
239000004097 EU approved flavor enhancer Substances 0.000 abstract 1
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
235000011054 acetic acid Nutrition 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229960004372 aripiprazole Drugs 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000000796 flavoring agent Substances 0.000 abstract 1
235000019634 flavors Nutrition 0.000 abstract 1
235000019264 food flavour enhancer Nutrition 0.000 abstract 1
239000004310 lactic acid Substances 0.000 abstract 1
235000014655 lactic acid Nutrition 0.000 abstract 1
230000000873 masking effect Effects 0.000 abstract 1
239000003186 pharmaceutical solution Substances 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
239000011975 tartaric acid Substances 0.000 abstract 1
235000002906 tartaric acid Nutrition 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HR20030870A 2001-04-25 2003-10-24 Aripiprazole oral solution HRP20030870B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28671801P	2001-04-25	2001-04-25
PCT/US2002/013048 WO2002085366A1 (en)	2001-04-25	2002-04-24	Aripiprazole oral solution

Publications (2)

Publication Number	Publication Date
HRP20030870A2 HRP20030870A2 (en)	2004-06-30
HRP20030870B1 true HRP20030870B1 (en)	2011-10-31

Family

ID=23099862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20030870A HRP20030870B1 (en)	2001-04-25	2003-10-24	Aripiprazole oral solution

Country Status (37)

Country	Link
US (1)	US6977257B2 (cs)
EP (2)	EP2436384B2 (cs)
JP (1)	JP4401077B2 (cs)
KR (1)	KR100909329B1 (cs)
CN (1)	CN1512884B (cs)
AR (1)	AR033168A1 (cs)
AT (1)	ATE537831T1 (cs)
AU (1)	AU2002254722B2 (cs)
BG (1)	BG66177B1 (cs)
BR (1)	BR0208986A (cs)
CA (1)	CA2445276C (cs)
CY (1)	CY1112606T1 (cs)
CZ (1)	CZ306181B6 (cs)
DK (1)	DK1381367T3 (cs)
EE (1)	EE05581B1 (cs)
ES (1)	ES2377855T3 (cs)
GE (1)	GEP20053602B (cs)
HK (2)	HK1058316A1 (cs)
HR (1)	HRP20030870B1 (cs)
HU (1)	HU230456B1 (cs)
IL (2)	IL158202A0 (cs)
IS (1)	IS2863B (cs)
MX (1)	MXPA03009728A (cs)
MY (1)	MY129350A (cs)
NO (1)	NO324606B1 (cs)
NZ (1)	NZ528550A (cs)
PE (1)	PE20021086A1 (cs)
PL (1)	PL206882B1 (cs)
PT (1)	PT1381367E (cs)
RS (1)	RS52082B (cs)
RU (1)	RU2295960C2 (cs)
SK (1)	SK287948B6 (cs)
TW (1)	TWI337865B (cs)
UA (1)	UA76144C2 (cs)
UY (1)	UY27273A1 (cs)
WO (1)	WO2002085366A1 (cs)
ZA (1)	ZA200307797B (cs)

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US6770478B2 (en) *	2000-02-10	2004-08-03	The Regents Of The University Of California	Erythrocytic cells and method for preserving cells
ES2322953T3 (es) *	2002-08-20	2009-07-02	Bristol-Myers Squibb Company	Formulacion del complejo de aripiprazol y procedimiento.
CN1867359B (zh) *	2003-10-08	2010-12-15	马林克罗特公司	哌甲酯溶液及其制药用途和制备方法
UA82561C2 (uk)	2003-10-23	2008-04-25	Оцука Фармасьютикалз Ко., Лтд.	Стерильна ін'єкційна композиція арипіпразолу з контрольованим вивільненням, спосіб її виготовлення та спосіб лікування шизофренії
US20080234291A1 (en) *	2004-01-21	2008-09-25	Marc Karel Jozef Francois	Mitratapide Oral Solution
EP2279727A3 (en)	2005-09-15	2011-10-05	Elan Pharma International Limited	Nanoparticulate aripiprazole formulations
JP2008531738A (ja) *	2006-01-05	2008-08-14	テバファーマシューティカルインダストリーズリミティド	アリピプラゾールの乾燥製剤
DE602006004694D1 (de) *	2006-01-05	2009-02-26	Teva Pharma	Feuchtgranulierungsmethode zur Herstellung pharmazeutischer Aripiprazolzusammensetzungen
JP4892264B2 (ja) *	2006-03-30	2012-03-07	高田製薬株式会社	リスペリドン水性液剤
US20100021891A1 (en) *	2006-06-12	2010-01-28	Bernard Lerer	Rgs2 genotypes associated with extrapyramidal symptoms induced by antipsychotic medication
GB0618879D0 (en)	2006-09-26	2006-11-01	Zysis Ltd	Pharmaceutical compositions
EP2170279B1 (en) *	2007-07-31	2017-12-27	Otsuka Pharmaceutical Co., Ltd.	Methods for producing aripiprazole suspension and freeze-dried formulation
WO2009042166A1 (en) *	2007-09-25	2009-04-02	Panacos Pharmaceuticals, Inc.	Liquid bevirimat dosage forms for oral administration
GB2456183A (en) *	2008-01-04	2009-07-08	Gw Pharma Ltd	Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament
US8173621B2 (en)	2008-06-11	2012-05-08	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
KR20110104074A (ko)	2008-12-23	2011-09-21	파마셋 인코포레이티드	퓨린 뉴클레오시드의 합성
PA8855601A1 (es)	2008-12-23	2010-07-27		Forformidatos de nucleósidos
US8551973B2 (en)	2008-12-23	2013-10-08	Gilead Pharmasset Llc	Nucleoside analogs
TWI583692B (zh)	2009-05-20	2017-05-21	基利法瑪席特有限責任公司	核苷磷醯胺
US8815261B2 (en) *	2009-06-19	2014-08-26	Medrx Co., Ltd.	Composition for external application comprising aripiprazole and organic acid as active ingredients
TR201000948A1 (tr)	2010-02-09	2011-08-22	Sanovel İlaç San.Ve Ti̇c.A.Ş.	Aripiprazol formülasyonları.
US8563530B2 (en)	2010-03-31	2013-10-22	Gilead Pharmassel LLC	Purine nucleoside phosphoramidate
EP3290428B1 (en)	2010-03-31	2021-10-13	Gilead Pharmasset LLC	Tablet comprising crystalline (s)-isopropyl 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1 (2h)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
CA2794671C (en)	2010-03-31	2018-05-01	Gilead Pharmasset Llc	Stereoselective synthesis of phosphorus containing actives
WO2012075140A1 (en)	2010-11-30	2012-06-07	Pharmasset, Inc.	Compounds
LT3156056T (lt)	2011-03-18	2024-02-26	Alkermes Pharma Ireland Limited	Farmacinės kompozicijos, apimančios sorbitano esterius
JO3410B1 (ar)	2011-06-07	2019-10-20	Otsuka Pharma Co Ltd	تركيبة أريبيبرازول مجفف بالتبريد
GB2505860B (en) *	2011-06-27	2018-10-31	Shanghai Zhongxi Pharmaceutical Corp	Aripiprazole medicament formulation and preparation method therefor
CN102846616B (zh) *	2011-06-27	2015-05-06	上海中西制药有限公司	一种阿立哌唑制剂及其制备方法
JO3190B1 (ar) *	2011-10-19	2018-03-08	Otsuka Pharma Co Ltd	محلول للتناول عن طريق الفم
JP6333802B2 (ja)	2012-03-19	2018-05-30	アルカームスファーマアイルランドリミテッド	ベンジルアルコールを含む医薬組成物
EP2827867B1 (en)	2012-03-19	2019-11-06	Alkermes Pharma Ireland Limited	Pharmaceutical compositions comprising glycerol esters
AU2013235519C1 (en)	2012-03-19	2018-04-26	Alkermes Pharma Ireland Limited	Pharmaaceutical compositions comprising fatty acid esters
JOP20200109A1 (ar)	2012-04-23	2017-06-16	Otsuka Pharma Co Ltd	مستحضر قابل للحقن
JP5341282B1 (ja) *	2012-06-29	2013-11-13	丸石製薬株式会社	アリピプラゾールの経口医薬製剤
US20150174247A1 (en)	2012-06-29	2015-06-25	Maruishi Pharmaceutical Co., Ltd.	Oral pharmaceutical preparation of aripiprazole
KR101571670B1 (ko) *	2012-08-08	2015-11-25	주식회사 씨엠지제약	아리피프라졸을 포함하는 경구용 속용 필름 제제
EP2897592B1 (en)	2012-09-19	2020-02-19	Alkermes Pharma Ireland Limited	Pharmaceutical compositions having improved storage stability
EP2900217A1 (en) *	2012-09-26	2015-08-05	Bristol-Myers Squibb Company	Apixaban liquid formulations
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US20140107130A1 (en) *	2012-10-11	2014-04-17	Antrim Pharmaceuticals, LLC	Oral Solution Formulations of Aripiprazole
EP2908859B1 (en) *	2012-10-16	2017-05-17	Arven Ilac Sanayi ve Ticaret A.S.	Aripiprazole formulations
JP6440625B2 (ja)	2012-11-14	2018-12-19	ザ・ジョンズ・ホプキンス・ユニバーシティー	精神***病を処置するための方法および組成物
JP6203682B2 (ja) *	2013-07-10	2017-09-27	共和薬品工業株式会社	アリピプラゾール含有水性液剤
CN103393594A (zh) *	2013-08-22	2013-11-20	万特制药(海南)有限公司	一种新的阿立哌唑的制剂组合物
CN106132415A (zh)	2014-03-20	2016-11-16	奥克梅斯制药爱尔兰有限公司	具有增加的注射速度的阿立哌唑制剂
WO2016189504A1 (en) *	2015-05-28	2016-12-01	Leiutis Pharmaceuticals Pvt Ltd	Non-lyophilized compositions of aripiprazole and methods of preparation thereof
JP6039849B1 (ja) *	2015-06-12	2016-12-07	高田製薬株式会社	アリピプラゾール含有内用液剤
WO2017025930A1 (en)	2015-08-12	2017-02-16	Ftf Pharma Private Limited	Oral solution of aripiprazole
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CN109498556A (zh) *	2017-09-15	2019-03-22	万特制药(海南)有限公司	阿立哌唑口服溶液及其制备方法
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2002
- 2002-03-28 MY MYPI20021124A patent/MY129350A/en unknown
- 2002-04-15 AR ARP020101366A patent/AR033168A1/es unknown
- 2002-04-19 TW TW091108139A patent/TWI337865B/zh not_active IP Right Cessation
- 2002-04-24 CZ CZ2003-2821A patent/CZ306181B6/cs not_active IP Right Cessation
- 2002-04-24 BR BR0208986-6A patent/BR0208986A/pt active Search and Examination
- 2002-04-24 AU AU2002254722A patent/AU2002254722B2/en not_active Expired
- 2002-04-24 DK DK02723964.9T patent/DK1381367T3/da active
- 2002-04-24 NZ NZ528550A patent/NZ528550A/en not_active IP Right Cessation
- 2002-04-24 JP JP2002582939A patent/JP4401077B2/ja not_active Expired - Lifetime
- 2002-04-24 PL PL364666A patent/PL206882B1/pl unknown
- 2002-04-24 RU RU2003132426/15A patent/RU2295960C2/ru not_active IP Right Cessation
- 2002-04-24 PT PT02723964T patent/PT1381367E/pt unknown
- 2002-04-24 UY UY27273A patent/UY27273A1/es not_active Application Discontinuation
- 2002-04-24 GE GE5332A patent/GEP20053602B/en unknown
- 2002-04-24 WO PCT/US2002/013048 patent/WO2002085366A1/en active IP Right Grant
- 2002-04-24 CA CA002445276A patent/CA2445276C/en not_active Expired - Fee Related
- 2002-04-24 EP EP11190103.9A patent/EP2436384B2/en not_active Expired - Lifetime
- 2002-04-24 ES ES02723964T patent/ES2377855T3/es not_active Expired - Lifetime
- 2002-04-24 IL IL15820202A patent/IL158202A0/xx active IP Right Grant
- 2002-04-24 UA UA20031110599A patent/UA76144C2/uk unknown
- 2002-04-24 HU HU0303946A patent/HU230456B1/hu not_active IP Right Cessation
- 2002-04-24 MX MXPA03009728A patent/MXPA03009728A/es active IP Right Grant
- 2002-04-24 SK SK1264-2003A patent/SK287948B6/sk not_active IP Right Cessation
- 2002-04-24 CN CN028112148A patent/CN1512884B/zh not_active Ceased
- 2002-04-24 RS YU84703A patent/RS52082B/sr unknown
- 2002-04-24 EE EEP200300523A patent/EE05581B1/xx not_active IP Right Cessation
- 2002-04-24 AT AT02723964T patent/ATE537831T1/de active
- 2002-04-24 KR KR1020037013943A patent/KR100909329B1/ko active IP Right Grant
- 2002-04-24 US US10/131,304 patent/US6977257B2/en not_active Expired - Lifetime
- 2002-04-24 EP EP02723964A patent/EP1381367B1/en not_active Expired - Lifetime
- 2002-04-25 PE PE2002000346A patent/PE20021086A1/es not_active Application Discontinuation
2003
- 2003-10-01 IL IL158202A patent/IL158202A/en not_active IP Right Cessation
- 2003-10-01 BG BG108216A patent/BG66177B1/bg unknown
- 2003-10-06 ZA ZA200307797A patent/ZA200307797B/en unknown
- 2003-10-14 IS IS6994A patent/IS2863B/is unknown
- 2003-10-21 NO NO20034705A patent/NO324606B1/no not_active IP Right Cessation
- 2003-10-24 HR HR20030870A patent/HRP20030870B1/xx not_active IP Right Cessation
2004
- 2004-02-19 HK HK04101190.2A patent/HK1058316A1/xx not_active IP Right Cessation
2012
- 2012-03-14 CY CY20121100273T patent/CY1112606T1/el unknown
- 2012-09-28 HK HK12109608.1A patent/HK1168792A1/xx not_active IP Right Cessation

Patent Citations (1)

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Publication number	Priority date	Publication date	Assignee	Title
US5006528A (en) *	1988-10-31	1991-04-09	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivatives

Also Published As

Publication number	Publication date
YU84703A (sh)	2006-08-17
PE20021086A1 (es)	2002-12-14
JP4401077B2 (ja)	2010-01-20
IL158202A0 (en)	2004-05-12
ES2377855T3 (es)	2012-04-02
EP1381367B1 (en)	2011-12-21
HUP0303946A3 (en)	2005-06-28
PL364666A1 (en)	2004-12-13
CY1112606T1 (el)	2016-02-10
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