HRP20030193A2 - Use of benzophenanthridine alkaloids as the animal feed additive and as the medicament against intestinal inflammation - Google Patents

Use of benzophenanthridine alkaloids as the animal feed additive and as the medicament against intestinal inflammation Download PDF

Info

Publication number: HRP20030193A2
Authority: HR; Croatia
Prior art keywords: amino acids; alkaloids; animal feed; aromatic amino; benzophenanthridine alkaloids
Prior art date: 2000-09-15

Application number

HR20030193A

Other languages

English (en)

Croatian (hr)

Inventor

Roth Herrmann

Original Assignee

Roth Herrmann

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-15

Filing date

2003-03-14

Publication date

2005-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3688371&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20030193(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-03-14 Application filed by Roth Herrmann filed Critical Roth Herrmann

2005-10-31 Publication of HRP20030193A2 publication Critical patent/HRP20030193A2/hr

Links

229930015421 benzophenanthridine alkaloid Natural products 0.000 title claims description 22
150000008622 benzophenanthridines Chemical class 0.000 title claims description 22
239000003814 drug Substances 0.000 title claims description 8
206010061218 Inflammation Diseases 0.000 title claims description 6
230000004054 inflammatory process Effects 0.000 title claims description 6
230000000968 intestinal effect Effects 0.000 title claims description 5
235000019730 animal feed additive Nutrition 0.000 title claims description 3
241001465754 Metazoa Species 0.000 claims description 37
-1 aromatic amino acids Chemical class 0.000 claims description 28
241000218180 Papaveraceae Species 0.000 claims description 17
229930013930 alkaloid Natural products 0.000 claims description 16
SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 claims description 14
ZFRKQXVRDFCRJG-UHFFFAOYSA-N skatole Chemical compound C1=CC=C2C(C)=CNC2=C1 ZFRKQXVRDFCRJG-UHFFFAOYSA-N 0.000 claims description 12
239000000654 additive Substances 0.000 claims description 11
150000001413 amino acids Chemical class 0.000 claims description 11
102000004190 Enzymes Human genes 0.000 claims description 7
108090000790 Enzymes Proteins 0.000 claims description 7
PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 claims description 7
RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 claims description 7
102000004169 proteins and genes Human genes 0.000 claims description 7
108090000623 proteins and genes Proteins 0.000 claims description 7
230000015556 catabolic process Effects 0.000 claims description 6
239000000463 material Substances 0.000 claims description 6
235000018102 proteins Nutrition 0.000 claims description 6
229940074386 skatole Drugs 0.000 claims description 6
235000008733 Citrus aurantifolia Nutrition 0.000 claims description 4
235000011941 Tilia x europaea Nutrition 0.000 claims description 4
240000008042 Zea mays Species 0.000 claims description 4
235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 4
235000002017 Zea mays subsp mays Nutrition 0.000 claims description 4
235000005822 corn Nutrition 0.000 claims description 4
229940079593 drug Drugs 0.000 claims description 4
230000002255 enzymatic effect Effects 0.000 claims description 4
229910052500 inorganic mineral Inorganic materials 0.000 claims description 4
239000004571 lime Substances 0.000 claims description 4
235000010755 mineral Nutrition 0.000 claims description 4
239000011707 mineral Substances 0.000 claims description 4
235000015097 nutrients Nutrition 0.000 claims description 4
150000003839 salts Chemical class 0.000 claims description 4
235000002639 sodium chloride Nutrition 0.000 claims description 4
229910019142 PO4 Inorganic materials 0.000 claims description 3
230000000996 additive effect Effects 0.000 claims description 3
235000013339 cereals Nutrition 0.000 claims description 3
230000029087 digestion Effects 0.000 claims description 3
235000011868 grain product Nutrition 0.000 claims description 3
230000002401 inhibitory effect Effects 0.000 claims description 3
238000004519 manufacturing process Methods 0.000 claims description 3
235000021317 phosphate Nutrition 0.000 claims description 3
150000003013 phosphoric acid derivatives Chemical class 0.000 claims description 3
239000011782 vitamin Substances 0.000 claims description 3
235000013343 vitamin Nutrition 0.000 claims description 3
229940088594 vitamin Drugs 0.000 claims description 3
229930003231 vitamin Natural products 0.000 claims description 3
239000000284 extract Substances 0.000 claims description 2
210000001035 gastrointestinal tract Anatomy 0.000 claims description 2
230000007515 enzymatic degradation Effects 0.000 claims 2
235000005911 diet Nutrition 0.000 claims 1
230000037213 diet Effects 0.000 claims 1
239000000203 mixture Substances 0.000 claims 1
235000001014 amino acid Nutrition 0.000 description 31
INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 description 13
235000013372 meat Nutrition 0.000 description 6
FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 description 5
QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 5
QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 5
150000003797 alkaloid derivatives Chemical class 0.000 description 5
235000020997 lean meat Nutrition 0.000 description 5
229940084560 sanguinarine Drugs 0.000 description 5
YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 description 5
102000003823 Aromatic-L-amino-acid decarboxylases Human genes 0.000 description 4
108090000121 Aromatic-L-amino-acid decarboxylases Proteins 0.000 description 4
102000004031 Carboxy-Lyases Human genes 0.000 description 4
108090000489 Carboxy-Lyases Proteins 0.000 description 4
230000009471 action Effects 0.000 description 4
235000020776 essential amino acid Nutrition 0.000 description 4
239000003797 essential amino acid Substances 0.000 description 4
238000002474 experimental method Methods 0.000 description 4
235000013305 food Nutrition 0.000 description 4
230000036541 health Effects 0.000 description 4
238000002360 preparation method Methods 0.000 description 4
239000000047 product Substances 0.000 description 4
241000196324 Embryophyta Species 0.000 description 3
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 3
102000014171 Milk Proteins Human genes 0.000 description 3
108010011756 Milk Proteins Proteins 0.000 description 3
241000282887 Suidae Species 0.000 description 3
125000003118 aryl group Chemical group 0.000 description 3
238000000354 decomposition reaction Methods 0.000 description 3
239000004615 ingredient Substances 0.000 description 3
210000004347 intestinal mucosa Anatomy 0.000 description 3
210000000936 intestine Anatomy 0.000 description 3
229930182817 methionine Natural products 0.000 description 3
244000005700 microbiome Species 0.000 description 3
235000021239 milk protein Nutrition 0.000 description 3
210000003205 muscle Anatomy 0.000 description 3
WEEFNMFMNMASJY-UHFFFAOYSA-M 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;chloride Chemical compound [Cl-].C1=C2OCOC2=CC2=CC=C3C4=CC=C(OC)C(OC)=C4C=[N+](C)C3=C21 WEEFNMFMNMASJY-UHFFFAOYSA-M 0.000 description 2
LLEJIEBFSOEYIV-UHFFFAOYSA-N Chelerythrine Natural products C1=C2OCOC2=CC2=CC=C3C4=CC=C(OC)C(OC)=C4C=[N+](C)C3=C21 LLEJIEBFSOEYIV-UHFFFAOYSA-N 0.000 description 2
RATMHCJTVBHJSU-UHFFFAOYSA-N Dihydrochelerythrine Natural products C1=C2OCOC2=CC2=C(N(C)C(O)C=3C4=CC=C(C=3OC)OC)C4=CC=C21 RATMHCJTVBHJSU-UHFFFAOYSA-N 0.000 description 2
COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 2
239000004472 Lysine Substances 0.000 description 2
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 2
235000015241 bacon Nutrition 0.000 description 2
230000007423 decrease Effects 0.000 description 2
230000000694 effects Effects 0.000 description 2
235000020774 essential nutrients Nutrition 0.000 description 2
230000009931 harmful effect Effects 0.000 description 2
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 2
231100000614 poison Toxicity 0.000 description 2
239000003440 toxic substance Substances 0.000 description 2
241000271566 Aves Species 0.000 description 1
235000021537 Beetroot Nutrition 0.000 description 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
241001233914 Chelidonium majus Species 0.000 description 1
241001112696 Clostridia Species 0.000 description 1
241000224483 Coccidia Species 0.000 description 1
241000287828 Gallus gallus Species 0.000 description 1
244000068988 Glycine max Species 0.000 description 1
235000010469 Glycine max Nutrition 0.000 description 1
244000020551 Helianthus annuus Species 0.000 description 1
235000003222 Helianthus annuus Nutrition 0.000 description 1
QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 1
LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 description 1
240000007849 Macleaya cordata Species 0.000 description 1
208000018737 Parkinson disease Diseases 0.000 description 1
101710124727 Protein 19.2 Proteins 0.000 description 1
241000282849 Ruminantia Species 0.000 description 1
KQXDHUJYNAXLNZ-XQSDOZFQSA-N Salinomycin Chemical compound O1[C@@H]([C@@H](CC)C(O)=O)CC[C@H](C)[C@@H]1[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(C=C[C@@H](O)[C@@]3(O[C@@](C)(CC3)[C@@H]3O[C@@H](C)[C@@](O)(CC)CC3)O2)O1 KQXDHUJYNAXLNZ-XQSDOZFQSA-N 0.000 description 1
239000004189 Salinomycin Substances 0.000 description 1
241000607142 Salmonella Species 0.000 description 1
244000001385 Sanguinaria canadensis Species 0.000 description 1
241000862632 Soja Species 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 1
239000004473 Threonine Substances 0.000 description 1
235000021307 Triticum Nutrition 0.000 description 1
244000098338 Triticum aestivum Species 0.000 description 1
TVIUWRVHXUBTAZ-UHFFFAOYSA-N [Pb].N1C=C(C)C2=CC=CC=C12 Chemical compound [Pb].N1C=C(C)C2=CC=CC=C12 TVIUWRVHXUBTAZ-UHFFFAOYSA-N 0.000 description 1
235000004279 alanine Nutrition 0.000 description 1
235000019463 artificial additive Nutrition 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
230000008901 benefit Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
230000000903 blocking effect Effects 0.000 description 1
YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
239000001506 calcium phosphate Substances 0.000 description 1
239000007795 chemical reaction product Substances 0.000 description 1
235000013330 chicken meat Nutrition 0.000 description 1
230000001684 chronic effect Effects 0.000 description 1
239000003224 coccidiostatic agent Substances 0.000 description 1
229960003067 cystine Drugs 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
239000003651 drinking water Substances 0.000 description 1
235000020188 drinking water Nutrition 0.000 description 1
238000006911 enzymatic reaction Methods 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
230000029142 excretion Effects 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
239000006052 feed supplement Substances 0.000 description 1
239000000945 filler Substances 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
239000013067 intermediate product Substances 0.000 description 1
244000000053 intestinal parasite Species 0.000 description 1
230000002427 irreversible effect Effects 0.000 description 1
210000004185 liver Anatomy 0.000 description 1
238000012423 maintenance Methods 0.000 description 1
238000000034 method Methods 0.000 description 1
229910000150 monocalcium phosphate Inorganic materials 0.000 description 1
235000019691 monocalcium phosphate Nutrition 0.000 description 1
210000004400 mucous membrane Anatomy 0.000 description 1
235000016709 nutrition Nutrition 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
244000045947 parasite Species 0.000 description 1
230000001717 pathogenic effect Effects 0.000 description 1
244000144977 poultry Species 0.000 description 1
235000013594 poultry meat Nutrition 0.000 description 1
230000008569 process Effects 0.000 description 1
230000009467 reduction Effects 0.000 description 1
229960001548 salinomycin Drugs 0.000 description 1
235000019378 salinomycin Nutrition 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000000126 substance Substances 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
235000013619 trace mineral Nutrition 0.000 description 1
239000011573 trace mineral Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Polymers & Plastics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Food Science & Technology (AREA)
Zoology (AREA)
Animal Husbandry (AREA)
Epidemiology (AREA)
Birds (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Fodder In General (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HR20030193A 2000-09-15 2003-03-14 Use of benzophenanthridine alkaloids as the animal feed additive and as the medicament against intestinal inflammation HRP20030193A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AT0157900A AT500455B1 (de)	2000-09-15	2000-09-15	Verwendung von benzophenanthridinalkaloiden als futteradditiv
PCT/IB2001/002487 WO2002021932A2 (de)	2000-09-15	2001-09-14	Futtermittel, futterzusatzmittel und heilmittel gegen darmentzündung

Publications (1)

Publication Number	Publication Date
HRP20030193A2 true HRP20030193A2 (en)	2005-10-31

Family

ID=3688371

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20030193A HRP20030193A2 (en)	2000-09-15	2003-03-14	Use of benzophenanthridine alkaloids as the animal feed additive and as the medicament against intestinal inflammation

Country Status (20)

Country	Link
US (1)	US20030190344A1 (hu)
EP (1)	EP1317188B2 (hu)
JP (1)	JP2004508059A (hu)
AT (1)	AT500455B1 (hu)
AU (1)	AU2002222354A1 (hu)
BG (1)	BG107626A (hu)
CA (1)	CA2422250A1 (hu)
CZ (1)	CZ299208B6 (hu)
DE (1)	DE50104706D1 (hu)
EE (1)	EE200300101A (hu)
ES (1)	ES2233706T5 (hu)
HR (1)	HRP20030193A2 (hu)
HU (1)	HUP0302433A3 (hu)
NO (1)	NO323687B1 (hu)
PL (1)	PL365902A1 (hu)
PT (1)	PT1317188E (hu)
RO (1)	RO121630B1 (hu)
SI (1)	SI21164B (hu)
SK (1)	SK285504B6 (hu)
WO (1)	WO2002021932A2 (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT500455B1 (de) †	2000-09-15	2007-08-15	Roth Hermann Dr	Verwendung von benzophenanthridinalkaloiden als futteradditiv
AT500589B1 (de) *	2004-05-19	2009-08-15	Roth Hermann Dr	Alkaloidhaltiges futtermittel bzw. futtermittelzusatz
EP1882473A1 (en) *	2006-07-28	2008-01-30	Indena S.P.A.	Use of anthocyanosides to prepare formulations for the treatment of mucositis induced by antitumoral drugs
AT504440B1 (de) *	2006-11-13	2012-03-15	Neufeld Klaus	Ballaststoff
AT506498B1 (de) *	2008-02-25	2011-02-15	Roth Hermann Dr	Verfahren zur fermentation von biomasse
AT509728B1 (de)	2010-04-15	2012-05-15	Neufeld Klaus	Verwendung eines alkaloidhältigen pflanzenextraktes beziehungsweise pflanzenmaterials als tierfutterzusatz
JP5385446B2 (ja) *	2012-11-12	2014-01-08	国立大学法人東京海洋大学	魚類のタンパク質節約を目的とした飼料
JP6253964B2 (ja) *	2013-11-29	2017-12-27	日本ニュートリション株式会社	牛乳の乳質改善剤および乳質改善方法
AT515336A1 (de) *	2014-02-03	2015-08-15	Roth Hermann Dr	Vermeidung oxidativer Prozesse und oxidativem Stress
WO2016056520A1 (ja) *	2014-10-06	2016-04-14	扶桑化学工業株式会社	水中動物用飼料、水中動物用発育向上剤、および、それらを用いた養殖魚の飼育方法
CN104351534B (zh) *	2014-11-03	2017-09-12	广东恒兴饲料实业股份有限公司	一种陆川猪用促生长饲料添加剂预混料及应用方法
US20170095467A1 (en) *	2015-10-01	2017-04-06	Rhizofeed, LLC	Encapsulation of isoquinoline alkaloids
MX2019000372A (es) *	2017-04-04	2019-08-29	Roth Hermann	Pienso con un agonista betaadrenergico y un alcaloide isoquinolinico.
CN107683970A (zh) *	2017-09-21	2018-02-13	香格里拉市利众种植农民专业合作社	藏香猪育肥饲料及其制备方法
CN107667969A (zh) *	2017-10-21	2018-02-09	赵三存	一种提高猪肉瘦肉率的育肥方法
CN107568458A (zh) *	2017-10-24	2018-01-12	山西大禹生物工程股份有限公司	一种免疫促进饲料添加剂
CN108567059B (zh) *	2018-05-09	2021-09-07	湖南弘康生态农业科技发展股份有限公司	一种猪饲料及其制备方法
EP3851116A1 (de) *	2020-01-20	2021-07-21	Phytobiotics Futterzusatzstoffe GmbH	Substanzkombination mit isochinolinalkaloiden und kokzidiostatikum oder kokzidioseimpfmittel
CN113480552B (zh) *	2021-06-04	2022-05-10	中国农业科学院北京畜牧兽医研究所	一种化合物及其在改善动物瘤胃微生物发酵中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4335110A (en) *	1979-08-23	1982-06-15	Orewa Inc.	Pharmaceutical compositions of sanguinaria galangal and zinc chloride
AU548560B2 (en) *	1980-05-20	1985-12-19	Vipont Laboratories Inc.	Benzophenanthridine alkaloids as antimicrobial agents
US5175000A (en) †	1987-06-30	1992-12-29	Vipont Pharmaceutical, Inc.	Free amine benzophenanthridine alkaloid compositions
JP2599158B2 (ja) *	1987-12-26	1997-04-09	日清製粉株式会社	家畜のカンピロバクター・ジェジュニ感染症の予防及び治療剤
JP2578488B2 (ja) *	1988-03-04	1997-02-05	協和醗酵工業株式会社	アミノ酸の製造法
AT403873B (de) *	1992-02-21	1998-06-25	Neufeld Klaus Dr	Tierfutter zur leistungssteigerung
NL1008054C2 (nl) *	1998-01-16	1999-07-19	Nl Zuivelonderzoek Inst	Werkwijze voor het produceren van alanine, alsmede hierbij toegepaste micro-organismen en recombinant DNA moleculen.
AT500455B1 (de) †	2000-09-15	2007-08-15	Roth Hermann Dr	Verwendung von benzophenanthridinalkaloiden als futteradditiv

2000
- 2000-09-15 AT AT0157900A patent/AT500455B1/de not_active IP Right Cessation
2001
- 2001-09-14 SI SI200120056A patent/SI21164B/sl not_active IP Right Cessation
- 2001-09-14 ES ES01984622T patent/ES2233706T5/es not_active Expired - Lifetime
- 2001-09-14 EE EEP200300101A patent/EE200300101A/xx unknown
- 2001-09-14 WO PCT/IB2001/002487 patent/WO2002021932A2/de active IP Right Grant
- 2001-09-14 SK SK300-2003A patent/SK285504B6/sk unknown
- 2001-09-14 PL PL01365902A patent/PL365902A1/xx not_active IP Right Cessation
- 2001-09-14 CZ CZ20030714A patent/CZ299208B6/cs not_active IP Right Cessation
- 2001-09-14 PT PT01984622T patent/PT1317188E/pt unknown
- 2001-09-14 JP JP2002526198A patent/JP2004508059A/ja active Pending
- 2001-09-14 US US10/380,447 patent/US20030190344A1/en not_active Abandoned
- 2001-09-14 AU AU2002222354A patent/AU2002222354A1/en not_active Abandoned
- 2001-09-14 DE DE50104706T patent/DE50104706D1/de not_active Expired - Lifetime
- 2001-09-14 EP EP01984622A patent/EP1317188B2/de not_active Expired - Lifetime
- 2001-09-14 RO ROA200300226A patent/RO121630B1/ro unknown
- 2001-09-14 HU HU0302433A patent/HUP0302433A3/hu unknown
- 2001-09-14 CA CA002422250A patent/CA2422250A1/en not_active Abandoned
2003
- 2003-03-11 BG BG107626A patent/BG107626A/bg unknown
- 2003-03-14 HR HR20030193A patent/HRP20030193A2/hr not_active Application Discontinuation
- 2003-03-14 NO NO20031196A patent/NO323687B1/no unknown

Also Published As

Publication number	Publication date
EP1317188B2 (de)	2008-06-11
BG107626A (bg)	2003-11-28
NO20031196D0 (no)	2003-03-14
ES2233706T3 (es)	2005-06-16
SK3002003A3 (en)	2003-08-05
PL365902A1 (en)	2005-01-10
ES2233706T5 (es)	2008-12-01
CA2422250A1 (en)	2003-03-14
WO2002021932A3 (de)	2002-10-17
HUP0302433A3 (en)	2006-02-28
RO121630B1 (ro)	2008-01-30
NO20031196L (no)	2003-05-15
NO323687B1 (no)	2007-06-25
AT500455B1 (de)	2007-08-15
AT500455A1 (de)	2005-12-15
WO2002021932A2 (de)	2002-03-21
PT1317188E (pt)	2005-04-29
SI21164B (sl)	2005-10-31
JP2004508059A (ja)	2004-03-18
SI21164A (sl)	2003-10-31
EP1317188A2 (de)	2003-06-11
US20030190344A1 (en)	2003-10-09
EE200300101A (et)	2005-02-15
DE50104706D1 (de)	2005-01-05
EP1317188B1 (de)	2004-12-01
CZ299208B6 (cs)	2008-05-21
SK285504B6 (sk)	2007-03-01
HUP0302433A2 (hu)	2003-10-28
AU2002222354A1 (en)	2002-03-26

Legal Events

Date	Code	Title	Description
2005-10-31	A1OB	Publication of a patent application
2006-04-19	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2006-08-22	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20060822 Year of fee payment: 6
2008-12-16	OBST	Application withdrawn

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