HN1997000058A - Derivados indolicos utiles para terapia - Google Patents

Derivados indolicos utiles para terapia

Info

Publication number
HN1997000058A
HN1997000058A HN1997000058A HN1997000058A HN1997000058A HN 1997000058 A HN1997000058 A HN 1997000058A HN 1997000058 A HN1997000058 A HN 1997000058A HN 1997000058 A HN1997000058 A HN 1997000058A HN 1997000058 A HN1997000058 A HN 1997000058A
Authority
HN
Honduras
Prior art keywords
therapy
derivatives useful
indolic derivatives
indolic
useful
Prior art date
Application number
HN1997000058A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HN1997000058A publication Critical patent/HN1997000058A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

LA PRESENTE INVENCION SE REFIERE A
HN1997000058A 1996-05-09 1997-04-29 Derivados indolicos utiles para terapia HN1997000058A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9609641.7A GB9609641D0 (en) 1996-05-09 1996-05-09 Compounds useful in therapy

Publications (1)

Publication Number Publication Date
HN1997000058A true HN1997000058A (es) 1997-06-26

Family

ID=10793387

Family Applications (1)

Application Number Title Priority Date Filing Date
HN1997000058A HN1997000058A (es) 1996-05-09 1997-04-29 Derivados indolicos utiles para terapia

Country Status (43)

Country Link
US (4) US6017945A (es)
EP (1) EP0901470B1 (es)
JP (1) JP3245179B2 (es)
KR (1) KR100331217B1 (es)
CN (1) CN1124262C (es)
AP (1) AP830A (es)
AR (1) AR007030A1 (es)
AT (1) ATE263151T1 (es)
AU (1) AU717849B2 (es)
BG (1) BG102873A (es)
BR (1) BR9709072A (es)
CA (1) CA2253876A1 (es)
CO (1) CO4650036A1 (es)
CZ (1) CZ292928B6 (es)
DE (1) DE69728392T2 (es)
DK (1) DK0901470T3 (es)
DZ (1) DZ2227A1 (es)
EA (1) EA001471B1 (es)
ES (1) ES2218675T3 (es)
GB (1) GB9609641D0 (es)
HK (1) HK1019149A1 (es)
HN (1) HN1997000058A (es)
HR (1) HRP970249B1 (es)
HU (1) HUP9901245A3 (es)
ID (1) ID16878A (es)
IL (1) IL125903A0 (es)
IS (1) IS1856B (es)
MA (1) MA26428A1 (es)
NO (1) NO312547B1 (es)
NZ (1) NZ332640A (es)
OA (1) OA10896A (es)
PE (1) PE65098A1 (es)
PL (1) PL329725A1 (es)
PT (1) PT901470E (es)
SI (1) SI0901470T1 (es)
SK (1) SK150398A3 (es)
TN (1) TNSN97078A1 (es)
TR (1) TR199802269T2 (es)
TW (1) TW491838B (es)
UA (1) UA50767C2 (es)
UY (1) UY24546A1 (es)
WO (1) WO1997043260A1 (es)
ZA (1) ZA973963B (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722287D0 (en) 1997-10-22 1997-12-17 Pfizer Ltd Compounds useful in therapy
CZ306810B6 (cs) 1999-02-10 2017-07-19 Astrazeneca Ab Použití chinazolinového derivátu jako inhibitoru angiogeneze
GB0016162D0 (en) * 2000-06-30 2000-08-23 Cancer Res Campaign Tech Indole-3-acetic acid derivatives
US20050203166A1 (en) * 2000-06-30 2005-09-15 Cancer Research Technology Limited Indole-3-acetic acid derivatives
TWI224101B (en) 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
DK1397130T3 (da) 2001-06-20 2007-11-12 Wyeth Corp Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1)
AR037097A1 (es) 2001-10-05 2004-10-20 Novartis Ag Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
UA80453C2 (en) 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
EP1569899B1 (en) 2002-12-10 2006-06-28 Wyeth Substituted 3-alkyl- and 3-arylalkyl-1h-indol-1-yl-acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
CN1726191A (zh) 2002-12-10 2006-01-25 惠氏公司 用作纤溶酶原激活物抑制剂－1(pai－1)的抑制剂的取代的吲哚氧代－乙酰氨基乙酸衍生物
DK1569900T3 (da) 2002-12-10 2006-10-23 Wyeth Corp Substituerede 3-carbonyl-1-yl-eddikesyrederivater som inhibitorer af plasminogenaktivator-inhibitor-1 (PAI-1)
CN1723198A (zh) 2002-12-10 2006-01-18 惠氏公司 用作纤溶酶原激活物抑制剂－1(pai－1)的抑制剂的芳基、芳氧基和烷氧基取代的1h－吲哚－3－基乙醛酸衍生物
EP1597254A1 (en) * 2003-01-22 2005-11-23 Eli Lilly and Company Indole-derivative modulators of steroid hormone nuclear receptors
US7342039B2 (en) 2003-09-25 2008-03-11 Wyeth Substituted indole oximes
US7411083B2 (en) 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7420083B2 (en) 2003-09-25 2008-09-02 Wyeth Substituted aryloximes
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7163954B2 (en) 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7141592B2 (en) 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7446201B2 (en) 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
JP2005109006A (ja) * 2003-09-29 2005-04-21 Tdk Corp 高電圧貫通型コンデンサ及びマグネトロン
HN2004000536A (es) 2003-12-16 2009-02-18 Wyeth Corp Un procediemiento de sintesis para la alquilacion reductiva de la posicon c-3 de indoles
MX2007002178A (es) 2004-08-23 2007-04-02 Wyeth Corp Acidos de oxazolo-naftilo como moduladores del inhibidor del activador de plasminogeno tipo 1 (pai-1) util en el tratamiento de trombosis y enfermedades cardiovasculares.
AU2006279496A1 (en) 2005-08-17 2007-02-22 Wyeth Substituted indoles and use thereof
JP2009533420A (ja) * 2006-04-13 2009-09-17 アクテリオン ファーマシューティカルズ リミテッド 早期特発性肺線維症の治療
DE102008030207A1 (de) 2008-06-25 2009-12-31 Bayer Schering Pharma Aktiengesellschaft Substituierte 7-Sulfanylmethyl-, 7-Sulfinylmethyl- und 7-Sulfonylmethyl-Indole und ihre Verwendung
DE102008030206A1 (de) 2008-06-25 2009-12-31 Bayer Schering Pharma Aktiengesellschaft 3-Cyanoalky- und 3-Hydroxyalkyl-Indole und ihre Verwendung
CN106674065A (zh) * 2016-12-07 2017-05-17 贵州大学 一种5‑卤代‑2‑烷氧基‑4‑甲苯磺酰氯制备方法
GB201817038D0 (en) * 2018-10-19 2018-12-05 Inflazome Ltd Novel processes
JP2022521789A (ja) 2019-02-27 2022-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 脳障害を治療するためのアゼピノ－インドール及び他の複素環化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE638840A (es) * 1962-09-14
DE1950346B2 (de) * 1968-10-08 1973-06-28 Sumitomo Chemical Co 2-indolylessigsaeureverbindungen und diese verbindungen enthaltende arzneipraeparate
US4397079A (en) * 1981-03-30 1983-08-09 International Business Machines Corp. Process for improving the yield of integrated devices including Schottky barrier diodes
US5245046A (en) * 1988-11-14 1993-09-14 The Upjohn Company α-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents
AU8641991A (en) * 1990-09-10 1992-03-30 Rhone-Poulenc Rorer International (Holdings) Inc. Substituted bicyclic aryl compounds exhibiting selective leukotriene b4 antagonist activity
ZA939516B (en) * 1992-12-22 1994-06-06 Smithkline Beecham Corp Endothelin receptor antagonists
ATE189217T1 (de) * 1993-03-19 2000-02-15 Merck & Co Inc Phenoxyphenylessigsäurederivate
GB9317096D0 (en) * 1993-08-17 1993-09-29 Pfizer Ltd Indoles

Also Published As

Publication number Publication date
HK1019149A1 (en) 2000-01-14
KR20000010879A (ko) 2000-02-25
TR199802269T2 (xx) 2001-12-21
AP830A (en) 2000-05-03
HRP970249B1 (en) 2003-06-30
NO985225D0 (no) 1998-11-09
NO985225L (no) 1998-11-09
ID16878A (id) 1997-11-20
NZ332640A (en) 2001-03-30
ES2218675T3 (es) 2004-11-16
NO312547B1 (no) 2002-05-27
KR100331217B1 (ko) 2002-05-09
PT901470E (pt) 2004-07-30
EA199800908A1 (ru) 1999-06-24
WO1997043260A1 (en) 1997-11-20
AR007030A1 (es) 1999-10-13
OA10896A (en) 2001-10-11
MA26428A1 (fr) 2004-12-20
SI0901470T1 (en) 2004-08-31
IS1856B (is) 2003-02-21
US6136843A (en) 2000-10-24
SK150398A3 (en) 1999-03-12
UA50767C2 (uk) 2002-11-15
CZ358298A3 (cs) 1999-08-11
IL125903A0 (en) 1999-04-11
EA001471B1 (ru) 2001-04-23
CN1216531A (zh) 1999-05-12
US6306852B1 (en) 2001-10-23
EP0901470A1 (en) 1999-03-17
CA2253876A1 (en) 1997-11-20
TW491838B (en) 2002-06-21
GB9609641D0 (en) 1996-07-10
PL329725A1 (en) 1999-04-12
EP0901470B1 (en) 2004-03-31
DZ2227A1 (fr) 2002-12-25
DE69728392T2 (de) 2005-01-13
JP3245179B2 (ja) 2002-01-07
DE69728392D1 (de) 2004-05-06
US6384070B2 (en) 2002-05-07
JPH11508285A (ja) 1999-07-21
CO4650036A1 (es) 1998-09-03
HUP9901245A2 (hu) 1999-08-30
CN1124262C (zh) 2003-10-15
PE65098A1 (es) 1998-10-29
AU2697897A (en) 1997-12-05
ZA973963B (en) 1998-11-09
TNSN97078A1 (fr) 2005-03-15
HRP970249A2 (en) 1998-06-30
IS4838A (is) 1998-08-28
UY24546A1 (es) 2000-09-29
US20010014677A1 (en) 2001-08-16
DK0901470T3 (da) 2004-07-12
AU717849B2 (en) 2000-04-06
HUP9901245A3 (en) 2002-01-28
US6017945A (en) 2000-01-25
CZ292928B6 (cs) 2004-01-14
BR9709072A (pt) 1999-08-03
AP9700982A0 (en) 1997-07-31
ATE263151T1 (de) 2004-04-15
BG102873A (en) 1999-11-30

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