HK1258717A1 - 氧雜硼雜環戊烷酯類及其用途 - Google Patents

氧雜硼雜環戊烷酯類及其用途

Info

Publication number: HK1258717A1
Authority: HK; Hong Kong
Prior art keywords: oxaborole; esters; oxaborole esters
Prior art date: 2016-05-12

Application number

HK19101118.4A

Other languages

English (en)

Inventor

赤間勉

D‧S‧卡特

J‧S‧哈樂戴

R‧T‧雅各布斯

劉陽

J‧J‧普拉特納

張永康

M‧J‧威蒂

Original Assignee

安納考爾醫藥公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-05-12

Filing date

2019-01-22

Publication date

2019-11-15

2019-01-22 Application filed by 安納考爾醫藥公司 filed Critical 安納考爾醫藥公司

2019-11-15 Publication of HK1258717A1 publication Critical patent/HK1258717A1/zh

Links

OHENQANLQNOMAO-UHFFFAOYSA-N oxaborole Chemical class O1B=CC=C1 OHENQANLQNOMAO-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pyrane Compounds (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

HK19101118.4A 2016-05-12 2019-01-22 氧雜硼雜環戊烷酯類及其用途 HK1258717A1 (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201662335565P	2016-05-12	2016-05-12
PCT/IB2017/052522 WO2017195069A1 (en)	2016-05-12	2017-05-01	Oxaborole esters and uses thereof

Publications (1)

Publication Number	Publication Date
HK1258717A1 true HK1258717A1 (zh)	2019-11-15

Family

ID=58699201

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK19101118.4A HK1258717A1 (zh)	2016-05-12	2019-01-22	氧雜硼雜環戊烷酯類及其用途

Country Status (31)

Country	Link
US (4)	US10562921B2 (zh)
EP (2)	EP3578562B1 (zh)
JP (2)	JP6715957B2 (zh)
KR (2)	KR102243775B1 (zh)
CN (2)	CN109503637B (zh)
AR (2)	AR108450A1 (zh)
AU (2)	AU2017263785B2 (zh)
BR (2)	BR122018076188A2 (zh)
CA (1)	CA3023490C (zh)
CL (2)	CL2018003187A1 (zh)
CO (1)	CO2018012077A2 (zh)
CR (2)	CR20180560A (zh)
DK (1)	DK3578562T3 (zh)
EA (2)	EA034415B1 (zh)
EC (2)	ECSP18091065A (zh)
ES (1)	ES2882782T3 (zh)
HK (1)	HK1258717A1 (zh)
HU (1)	HUE056320T2 (zh)
IL (2)	IL262453A (zh)
MA (1)	MA44968A (zh)
MX (2)	MX2018013743A (zh)
NI (2)	NI201801172A (zh)
NZ (1)	NZ746906A (zh)
PE (2)	PE20191077A1 (zh)
PT (1)	PT3578562T (zh)
SG (1)	SG11201809237RA (zh)
TN (2)	TN2019000106A1 (zh)
TW (1)	TWI629279B (zh)
UA (2)	UA120999C2 (zh)
UY (2)	UY37236A (zh)
WO (1)	WO2017195069A1 (zh)

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US10070649B2 (en)	2013-01-30	2018-09-11	Agrofresh Inc.	Volatile applications against pathogens
US11039617B2 (en)	2013-01-30	2021-06-22	Agrofresh Inc.	Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
RS64770B1 (sr)	2016-03-07	2023-11-30	Agrofresh Inc	Sinergistički postupci upotrebe jedinjenja benzoksaborola i gasova za prezerviranje kao antimikrobnih agenasa za useve
EP3578562B1 (en) *	2016-05-12	2021-06-23	Anacor Pharmaceuticals, Inc	L-valinate amide benzoxaborole derivatives for the treatment of parasitic diseases
CN111655035A (zh) *	2017-11-30	2020-09-11	博瑞金股份有限公司	苯并氧杂硼杂环戊烯化合物和其制剂
JP2020180170A (ja) *	2019-04-23	2020-11-05	東ソー株式会社	ハロゲン含有ポリエーテルポリオール組成物

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FR2588189B1 (fr)	1985-10-03	1988-12-02	Merck Sharp & Dohme	Composition pharmaceutique de type a transition de phase liquide-gel
DE69212850T2 (de)	1991-01-15	1997-03-06	Alcon Lab Inc	Verwendung von Karrageenan in topischen ophthalmologischen Zusammensetzungen
US5212162A (en)	1991-03-27	1993-05-18	Alcon Laboratories, Inc.	Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
GB9411587D0 (en)	1994-06-09	1994-08-03	Zeneca Ltd	Compound, composition and use
US6309853B1 (en)	1994-08-17	2001-10-30	The Rockfeller University	Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
JO3396B1 (ar)	2007-06-20	2019-10-20	Anacor Pharmaceuticals Inc	جزيئات صغيرة تحتوي على البورون
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AR088669A1 (es)	2011-11-21	2014-06-25	Lilly Co Eli	Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
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WO2015097276A1 (en) *	2013-12-23	2015-07-02	Syngenta Participations Ag	Benzoxaborole fungicides
WO2017029289A1 (en) *	2015-08-17	2017-02-23	Syngenta Participations Ag	1-hydroxy-3h-2,1-benzoxaborole derivatives and their use as microbiocides
EP3578562B1 (en) *	2016-05-12	2021-06-23	Anacor Pharmaceuticals, Inc	L-valinate amide benzoxaborole derivatives for the treatment of parasitic diseases

2017
- 2017-05-01 EP EP19180969.8A patent/EP3578562B1/en active Active
- 2017-05-01 EA EA201892203A patent/EA034415B1/ru unknown
- 2017-05-01 EP EP17722886.3A patent/EP3455227A1/en not_active Withdrawn
- 2017-05-01 UA UAA201810456A patent/UA120999C2/uk unknown
- 2017-05-01 DK DK19180969.8T patent/DK3578562T3/da active
- 2017-05-01 NZ NZ746906A patent/NZ746906A/en not_active IP Right Cessation
- 2017-05-01 TN TNP/2019/000106A patent/TN2019000106A1/en unknown
- 2017-05-01 BR BR122018076188A patent/BR122018076188A2/pt not_active Application Discontinuation
- 2017-05-01 KR KR1020187035848A patent/KR102243775B1/ko active IP Right Grant
- 2017-05-01 HU HUE19180969A patent/HUE056320T2/hu unknown
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- 2017-05-01 CN CN201811522724.7A patent/CN109503637B/zh active Active
- 2017-05-01 UA UAA201811418A patent/UA121354C2/uk unknown
- 2017-05-01 JP JP2018559924A patent/JP6715957B2/ja not_active Expired - Fee Related
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- 2017-05-01 PT PT191809698T patent/PT3578562T/pt unknown
- 2017-05-01 TN TNP/2018/000351A patent/TN2018000351A1/en unknown
- 2017-05-01 CN CN201780029103.2A patent/CN109153688A/zh active Pending
- 2017-05-01 MA MA044968A patent/MA44968A/fr unknown
- 2017-05-01 WO PCT/IB2017/052522 patent/WO2017195069A1/en active Application Filing
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- 2017-05-01 PE PE2019000887A patent/PE20191077A1/es unknown
- 2017-05-01 ES ES19180969T patent/ES2882782T3/es active Active
- 2017-05-01 PE PE2018002055A patent/PE20190119A1/es unknown
- 2017-05-01 AU AU2017263785A patent/AU2017263785B2/en not_active Ceased
- 2017-05-09 US US15/590,159 patent/US10562921B2/en active Active
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- 2017-05-10 UY UY0001037236A patent/UY37236A/es unknown
- 2017-05-11 AR ARP170101250A patent/AR108450A1/es unknown
2018
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- 2018-11-09 CL CL2018003187A patent/CL2018003187A1/es unknown
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- 2018-11-09 NI NI2018001171A patent/NI201801171A/es unknown
- 2018-11-16 AU AU2018264116A patent/AU2018264116B2/en not_active Ceased
- 2018-11-20 IL IL263161A patent/IL263161B/en unknown
- 2018-11-22 UY UY0001037980A patent/UY37980A/es unknown
- 2018-11-23 AR ARP180103435A patent/AR113543A2/es unknown
- 2018-11-27 CL CL2018003377A patent/CL2018003377A1/es unknown
- 2018-12-11 EC ECSENADI201891065A patent/ECSP18091065A/es unknown
2019
- 2019-01-22 HK HK19101118.4A patent/HK1258717A1/zh unknown
- 2019-01-24 JP JP2019009932A patent/JP6715966B2/ja not_active Expired - Fee Related
- 2019-04-12 EC ECSENADI201926702A patent/ECSP19026702A/es unknown
- 2019-09-24 US US16/580,676 patent/US10882872B2/en active Active
2020
- 2020-12-01 US US17/108,066 patent/US11578087B2/en active Active
2022
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Also Published As

Publication number	Publication date
AR108450A1 (es)	2018-08-22
US20230132298A1 (en)	2023-04-27
BR112018071931A2 (pt)	2019-02-05
CO2018012077A2 (es)	2018-11-22
CN109153688A (zh)	2019-01-04
TN2018000351A1 (en)	2020-06-15
ECSP19026702A (es)	2019-06-30
CA3023490C (en)	2021-06-08
PE20191077A1 (es)	2019-08-20
IL262453A (en)	2018-12-31
UY37980A (es)	2020-06-30
UA120999C2 (uk)	2020-03-10
AU2018264116B2 (en)	2020-03-12
KR102243775B1 (ko)	2021-04-22
JP2019520326A (ja)	2019-07-18
TN2019000106A1 (en)	2020-10-05
HUE056320T2 (hu)	2022-02-28
IL263161B (en)	2022-05-01
KR102231489B1 (ko)	2021-03-23
TW201808968A (zh)	2018-03-16
US20170327519A1 (en)	2017-11-16
ES2882782T3 (es)	2021-12-02
US20210101916A1 (en)	2021-04-08
KR20190002695A (ko)	2019-01-08
AU2018264116A1 (en)	2018-12-06
CN109503637A (zh)	2019-03-22
JP2019081770A (ja)	2019-05-30
EA201892203A1 (ru)	2019-04-30
IL263161A (en)	2018-12-31
AU2017263785A1 (en)	2018-10-25
CL2018003187A1 (es)	2019-01-11
CN109503637B (zh)	2021-03-16
EA034415B1 (ru)	2020-02-05
AU2017263785B2 (en)	2019-10-03
EA201892475A1 (ru)	2019-04-30
UA121354C2 (uk)	2020-05-12
KR20190005982A (ko)	2019-01-16
EP3578562B1 (en)	2021-06-23
US10882872B2 (en)	2021-01-05
EP3578562A1 (en)	2019-12-11
NZ746906A (en)	2020-06-26
NI201801172A (es)	2019-04-10
PE20190119A1 (es)	2019-01-17
BR122023022427A2 (pt)	2023-12-26
CR20180560A (es)	2019-01-25
UY37236A (es)	2018-01-02
CA3023490A1 (en)	2017-11-16
WO2017195069A1 (en)	2017-11-16
MA44968A (fr)	2019-03-20
EP3455227A1 (en)	2019-03-20
BR122018076188A2 (pt)	2019-09-10
US20200017531A1 (en)	2020-01-16
JP6715966B2 (ja)	2020-07-01
EA036661B1 (ru)	2020-12-04
JP6715957B2 (ja)	2020-07-01
DK3578562T3 (da)	2021-07-12
SG11201809237RA (en)	2018-11-29
MX2018015410A (es)	2019-05-27
AR113543A2 (es)	2020-05-13
CR20180502A (es)	2018-12-21
PT3578562T (pt)	2021-08-05
CL2018003377A1 (es)	2019-01-11
MX2018013743A (es)	2019-05-02
US11578087B2 (en)	2023-02-14
NI201801171A (es)	2019-04-10
TWI629279B (zh)	2018-07-11
US10562921B2 (en)	2020-02-18
ECSP18091065A (es)	2019-07-31

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