HK1254129A1 - 給予谷氨酰胺酶抑制劑的方法 - Google Patents

給予谷氨酰胺酶抑制劑的方法

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Publication number
HK1254129A1
HK1254129A1 HK18113200.9A HK18113200A HK1254129A1 HK 1254129 A1 HK1254129 A1 HK 1254129A1 HK 18113200 A HK18113200 A HK 18113200A HK 1254129 A1 HK1254129 A1 HK 1254129A1
Authority
HK
Hong Kong
Prior art keywords
administering
methods
glutaminase inhibitors
glutaminase
inhibitors
Prior art date
Application number
HK18113200.9A
Other languages
English (en)
Inventor
Matthew I Gross
Mark K Bennett
Christopher Molineaux
Original Assignee
Calithera Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calithera Biosciences Inc filed Critical Calithera Biosciences Inc
Publication of HK1254129A1 publication Critical patent/HK1254129A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK18113200.9A 2015-03-30 2018-10-16 給予谷氨酰胺酶抑制劑的方法 HK1254129A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562139928P 2015-03-30 2015-03-30
US201562168112P 2015-05-29 2015-05-29
PCT/US2016/024998 WO2016160980A1 (en) 2015-03-30 2016-03-30 Methods of administering glutaminase inhibitors

Publications (1)

Publication Number Publication Date
HK1254129A1 true HK1254129A1 (zh) 2019-07-12

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Country Status (14)

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US (1) US20160287564A1 (zh)
EP (1) EP3277276B1 (zh)
JP (1) JP6768693B2 (zh)
KR (1) KR20170131650A (zh)
CN (1) CN107921031A (zh)
AU (1) AU2016243631B2 (zh)
BR (1) BR112017020780A2 (zh)
CA (1) CA2981499A1 (zh)
EA (1) EA037152B1 (zh)
HK (1) HK1254129A1 (zh)
IL (1) IL254779A0 (zh)
MX (1) MX2017012408A (zh)
SG (1) SG11201708034SA (zh)
WO (1) WO2016160980A1 (zh)

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* Cited by examiner, † Cited by third party
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US8604016B2 (en) 2011-11-21 2013-12-10 Calithera Biosciences Inc. Heterocyclic inhibitors of glutaminase
EA029707B1 (ru) 2012-11-16 2018-05-31 Калитера Байосайенсиз, Инк. Гетероциклические ингибиторы глютаминазы
EA033919B1 (ru) 2014-04-30 2019-12-10 Пфайзер Инк. Соединённые циклоалкилом дигетероциклические производные
JP6889101B2 (ja) 2014-08-07 2021-06-18 キャリセラ バイオサイエンシーズ， インコーポレイテッド グルタミナーゼ阻害剤の結晶形態
AU2016246521B2 (en) * 2015-04-06 2020-07-09 Calithera Biosciences, Inc. Treatment of lung cancer with inhibitors of glutaminase
WO2017062354A1 (en) 2015-10-05 2017-04-13 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors and immuno-oncology agents
CA3034890A1 (en) 2016-08-25 2018-03-01 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
CN109982703A (zh) 2016-08-25 2019-07-05 卡利泰拉生物科技公司 用谷氨酰胺酶抑制剂的组合疗法
WO2018102715A1 (en) * 2016-12-02 2018-06-07 Indiana University Research And Technology Corporation Compositions and methods for treating and/or reducing corneal dystrophy
WO2020086440A1 (en) * 2018-10-22 2020-04-30 Beth Israel Deaconess Medical Center Immunomodulatory compounds
US20240016775A1 (en) * 2020-02-24 2024-01-18 Fukang (Shanghai) Health Technology Co., Ltd Anti-coronavirus application of poly adp ribose polymerase inhibitor
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