HK1249409B - 5-bromo-2,6-di-(1h-pyrazol-l-yl)pyrimidin-4-amine for use in the treatment of cancer - Google Patents
5-bromo-2,6-di-(1h-pyrazol-l-yl)pyrimidin-4-amine for use in the treatment of cancerInfo
- Publication number
- HK1249409B HK1249409B HK18108031.4A HK18108031A HK1249409B HK 1249409 B HK1249409 B HK 1249409B HK 18108031 A HK18108031 A HK 18108031A HK 1249409 B HK1249409 B HK 1249409B
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrazol
- pyrimidin
- bromo
- cancer
- amine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15382425 | 2015-08-11 | ||
US201662335984P | 2016-05-13 | 2016-05-13 | |
PCT/IB2016/054834 WO2017025918A1 (en) | 2015-08-11 | 2016-08-10 | 5-bromo-2,6-di-(lh-pyrazol-l-yl)pyrimidin-4-amine for use in the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1249409B true HK1249409B (en) | 2020-05-08 |
Family
ID=65563017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18108031.4A HK1249409B (en) | 2015-08-11 | 2018-06-22 | 5-bromo-2,6-di-(1h-pyrazol-l-yl)pyrimidin-4-amine for use in the treatment of cancer |
Country Status (13)
Country | Link |
---|---|
JP (1) | JP6964113B2 (en) |
KR (1) | KR102226100B1 (en) |
CL (1) | CL2018000349A1 (en) |
DK (1) | DK3334431T3 (en) |
ES (1) | ES2761910T3 (en) |
HK (1) | HK1249409B (en) |
HR (1) | HRP20192192T1 (en) |
HU (1) | HUE046646T2 (en) |
IL (1) | IL257350A (en) |
LT (1) | LT3334431T (en) |
PT (1) | PT3334431T (en) |
RU (1) | RU2745560C2 (en) |
ZA (1) | ZA201800792B (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2365960B1 (en) * | 2010-03-31 | 2012-06-04 | Palobiofarma, S.L | NEW ANTAGONISTS OF ADENOSINE RECEPTORS. |
-
2016
- 2016-08-10 DK DK16766384.8T patent/DK3334431T3/en active
- 2016-08-10 ES ES16766384T patent/ES2761910T3/en active Active
- 2016-08-10 RU RU2018108050A patent/RU2745560C2/en active
- 2016-08-10 LT LTEP16766384.8T patent/LT3334431T/en unknown
- 2016-08-10 KR KR1020207013977A patent/KR102226100B1/en active IP Right Grant
- 2016-08-10 HU HUE16766384A patent/HUE046646T2/en unknown
- 2016-08-10 PT PT167663848T patent/PT3334431T/en unknown
-
2018
- 2018-02-04 IL IL257350A patent/IL257350A/en active IP Right Grant
- 2018-02-07 CL CL2018000349A patent/CL2018000349A1/en unknown
- 2018-02-07 ZA ZA2018/00792A patent/ZA201800792B/en unknown
- 2018-06-22 HK HK18108031.4A patent/HK1249409B/en unknown
-
2019
- 2019-06-18 JP JP2019112726A patent/JP6964113B2/en active Active
- 2019-12-04 HR HRP20192192TT patent/HRP20192192T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2761910T3 (en) | 2020-05-21 |
IL257350A (en) | 2018-03-29 |
ZA201800792B (en) | 2019-06-26 |
KR102226100B1 (en) | 2021-03-10 |
KR20200057790A (en) | 2020-05-26 |
RU2018108050A (en) | 2019-09-13 |
JP6964113B2 (en) | 2021-11-10 |
DK3334431T3 (en) | 2020-01-02 |
PT3334431T (en) | 2020-01-06 |
LT3334431T (en) | 2019-12-27 |
JP2019218346A (en) | 2019-12-26 |
HRP20192192T1 (en) | 2020-03-06 |
CL2018000349A1 (en) | 2018-09-07 |
RU2745560C2 (en) | 2021-03-29 |
HUE046646T2 (en) | 2020-03-30 |
RU2018108050A3 (en) | 2020-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AM | Amended specification (according sect 146 of patent law) |
Free format text: NOVARTIS A Effective date: 20210119 |