HK1245345A1 - 腫瘤樣本的多基因分析 - Google Patents

腫瘤樣本的多基因分析

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Publication number
HK1245345A1
HK1245345A1 HK18104579.1A HK18104579A HK1245345A1 HK 1245345 A1 HK1245345 A1 HK 1245345A1 HK 18104579 A HK18104579 A HK 18104579A HK 1245345 A1 HK1245345 A1 HK 1245345A1
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HK
Hong Kong
Prior art keywords
tumor samples
multigene analysis
multigene
analysis
tumor
Prior art date
Application number
HK18104579.1A
Other languages
English (en)
Inventor
Geoffrey Alan Otto
Michelle Nahas
Doron Lipson
Original Assignee
Found Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Found Medicine Inc filed Critical Found Medicine Inc
Publication of HK1245345A1 publication Critical patent/HK1245345A1/zh

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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

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  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Data Mining & Analysis (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK18104579.1A 2014-12-05 2018-04-09 腫瘤樣本的多基因分析 HK1245345A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462088457P 2014-12-05 2014-12-05
PCT/US2015/064044 WO2016090273A1 (en) 2014-12-05 2015-12-04 Multigene analysis of tumor samples

Publications (1)

Publication Number Publication Date
HK1245345A1 true HK1245345A1 (zh) 2018-08-24

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HK18104579.1A HK1245345A1 (zh) 2014-12-05 2018-04-09 腫瘤樣本的多基因分析

Country Status (7)

Country Link
US (1) US11959141B2 (zh)
EP (2) EP4112738B1 (zh)
JP (2) JP6905934B2 (zh)
AU (2) AU2015357573B2 (zh)
CA (1) CA2967447A1 (zh)
HK (1) HK1245345A1 (zh)
WO (1) WO2016090273A1 (zh)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013016708B1 (pt) 2010-12-30 2021-08-17 Foundation Medicine, Inc Otimização de análise multigene de amostras de tumor
AU2012242847B2 (en) 2011-04-15 2017-01-19 The Johns Hopkins University Safe sequencing system
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
US11525163B2 (en) 2012-10-29 2022-12-13 The Johns Hopkins University Papanicolaou test for ovarian and endometrial cancers
CN105531375B (zh) 2012-12-10 2020-03-03 分析生物科学有限公司 靶向基因组分析的方法
AU2015357573B2 (en) 2014-12-05 2022-04-07 Foundation Medicine, Inc. Multigene analysis of tumor samples
AU2016218631B2 (en) 2015-02-10 2022-03-10 The Chinese University Of Hong Kong Detecting mutations for cancer screening and fetal analysis
TWI802886B (zh) 2015-07-23 2023-05-21 香港中文大學 游離dna(cell-free dna)之片段化模式分析
WO2017027653A1 (en) 2015-08-11 2017-02-16 The Johns Hopkins University Assaying ovarian cyst fluid
CA3004435A1 (en) 2015-11-11 2017-05-18 Resolution Bioscience, Inc. High efficiency construction of dna libraries
EP3443149B1 (en) * 2016-04-15 2024-08-14 University Health Network (UHN) Hybrid-capture sequencing for determining immune cell clonality
JP7093764B2 (ja) * 2016-08-03 2022-06-30 セルジーン コーポレイション 骨髄異形成症候群の治療方法
JP7217224B2 (ja) 2016-08-25 2023-02-02 レゾリューション バイオサイエンス, インコーポレイテッド Dna試料中のゲノムコピー変化の検出方法
MY195527A (en) 2016-10-24 2023-01-30 Grail Inc Methods And Systems For Tumor Detection
MY197535A (en) 2017-01-25 2023-06-21 Univ Hong Kong Chinese Diagnostic applications using nucleic acid fragments
US11421281B2 (en) 2017-02-23 2022-08-23 University Of Iowa Research Foundation Methods for identification of driver mutations in a patient tumor by mutation processing based reconstruction of tumor developmental history
CA3064312A1 (en) 2017-05-30 2018-12-06 University Health Network Hybrid-capture sequencing for determining immune cell clonality
MX2020001575A (es) 2017-08-07 2020-11-18 Univ Johns Hopkins Materiales y métodos para evaluar y tratar el cáncer.
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
US11773449B2 (en) 2017-09-01 2023-10-03 The Hospital For Sick Children Profiling and treatment of hypermutant cancer
WO2019113563A1 (en) * 2017-12-09 2019-06-13 Viome, Inc. Methods for nucleic acid library creation
SG11202007225TA (en) 2018-01-29 2020-08-28 St Jude Childrens Res Hospital Inc Method for nucleic acid amplification
JP7217893B2 (ja) * 2018-02-06 2023-02-06 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン 光学組織像の分析及び遠隔読影のためのシステム及び方法
EP3775198A4 (en) 2018-04-02 2022-01-05 Grail, Inc. METHYLATION MARKERS AND TARGETED METHYLATION PROBE PANELS
CN110468201B (zh) * 2018-05-11 2023-08-11 中国医学科学院肿瘤医院 Escc频繁突变基因的靶向测序及其在获得判断escc预后的生物标记物中的应用
US10801064B2 (en) 2018-05-31 2020-10-13 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
US11814750B2 (en) 2018-05-31 2023-11-14 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
BR112020024727A2 (pt) * 2018-06-11 2021-03-23 Foundation Medicine, Inc. composições e métodos para avaliação de alterações genômicas
HRP20231295T1 (hr) 2018-07-10 2024-02-02 Novartis Ag Derivati 3-(5-hidroksi-1-oksoizoindolin-2-il)piperidin-2,6-diona i njihova upotreba u liječenju bolesti ovisnih o cinkovom prstu 2 (ikzf2) obitelji ikaros
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
WO2020069350A1 (en) 2018-09-27 2020-04-02 Grail, Inc. Methylation markers and targeted methylation probe panel
AU2020313915A1 (en) * 2019-07-12 2022-02-24 Tempus Ai, Inc. Adaptive order fulfillment and tracking methods and systems
CN110716044B (zh) * 2019-10-23 2023-04-18 郑州大学 一种用于食管鳞癌早期筛查和诊断的血清蛋白标志物、试剂盒及检测方法
CN113275053A (zh) 2020-02-03 2021-08-20 帝肯基因组学公司 试剂存储***
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
EP4139477A4 (en) * 2020-04-21 2024-05-22 Tempus AI, Inc. TCR/BCR PROFILING
CN112322716B (zh) * 2020-11-25 2021-07-30 深圳泛因医学有限公司 基于tcr/bcr高通量测序的特定淋巴细胞含量分析方法及装置
CN116064792B (zh) * 2022-08-11 2023-10-27 山东大学 一种用于结直肠癌诊断的多基因dna甲基化联合检测试剂盒及应用
CN116445478B (zh) * 2023-06-12 2023-09-05 北京旌准医疗科技有限公司 一种构建ighv基因文库的引物组合及其应用

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495676B1 (en) 1993-04-13 2002-12-17 Naxcor Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
US20040161741A1 (en) 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
US20040022764A1 (en) 2002-07-31 2004-02-05 Hanan Polansky Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease
CA2727850C (en) 2003-01-29 2013-04-30 454 Corporation Methods of amplifying and sequencing nucleic acids
US20050209787A1 (en) 2003-12-12 2005-09-22 Waggener Thomas B Sequencing data analysis
CA2557841A1 (en) 2004-02-27 2005-09-09 President And Fellows Of Harvard College Polony fluorescent in situ sequencing beads
TWI287041B (en) 2005-04-27 2007-09-21 Jung-Tang Huang An ultra-rapid DNA sequencing method with nano-transistors array based devices
US20060275779A1 (en) 2005-06-03 2006-12-07 Zhiyong Li Method and apparatus for molecular analysis using nanowires
US20070194225A1 (en) 2005-10-07 2007-08-23 Zorn Miguel D Coherent electron junction scanning probe interference microscope, nanomanipulator and spectrometer with assembler and DNA sequencing applications
US8383338B2 (en) 2006-04-24 2013-02-26 Roche Nimblegen, Inc. Methods and systems for uniform enrichment of genomic regions
US20080131887A1 (en) 2006-11-30 2008-06-05 Stephan Dietrich A Genetic Analysis Systems and Methods
EP2152908B1 (en) 2007-05-03 2017-03-15 One Lambda, Inc. Methods of screening for binding interaction using sets of microparticles and unique probes
US8518640B2 (en) 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
EP2245198A1 (en) 2008-02-04 2010-11-03 Massachusetts Institute of Technology Selection of nucleic acids by solution hybridization to oligonucleotide baits
AU2009288097B2 (en) 2008-09-03 2013-11-14 The Johns Hopkins University Pathways underlying pancreatic tumorigenesis and an hereditary pancreatic cancer gene
US8748103B2 (en) * 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US8628927B2 (en) * 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
EP2370813A4 (en) 2008-12-04 2012-05-23 Univ California MATERIALS AND METHODS FOR DIAGNOSIS AND PROGNOSIS OF PROSTATE CANCER
CN101619350B (zh) 2009-01-23 2012-05-16 周宏灏 用于恶性肿瘤个体化用药相关基因突变检测的基因芯片及其应用
US20100216648A1 (en) 2009-02-20 2010-08-26 Febit Holding Gmbh Synthesis of sequence-verified nucleic acids
US20100286143A1 (en) 2009-04-24 2010-11-11 Dora Dias-Santagata Methods and materials for genetic analysis of tumors
WO2010141955A2 (en) 2009-06-05 2010-12-09 Myriad Genetics, Inc. Methods of detecting cancer
CN103097888B (zh) 2010-05-06 2016-03-09 赛昆塔有限责任公司 利用克隆型谱监测健康和疾病状态
BR112013016708B1 (pt) 2010-12-30 2021-08-17 Foundation Medicine, Inc Otimização de análise multigene de amostras de tumor
DK2748192T3 (en) 2011-08-23 2019-02-25 Found Medicine Inc KIF5B-RET-FUSION MOLECULES AND APPLICATIONS THEREOF
US10424394B2 (en) 2011-10-06 2019-09-24 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
CA2853088C (en) * 2011-10-21 2018-03-13 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
US11261494B2 (en) * 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
SG10201610861XA (en) * 2012-07-03 2017-02-27 Integrated Dna Tech Inc Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection
KR20220061271A (ko) 2012-09-04 2022-05-12 가던트 헬쓰, 인크. 희귀 돌연변이 및 카피수 변이를 검출하기 위한 시스템 및 방법
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
WO2014130975A1 (en) * 2013-02-22 2014-08-28 Bastian Boris C Fusion polynucleotides and fusion polypeptides associated with cancer and particularly melanoma and their uses as therapeutic and diagnostic targets
AU2014249273A1 (en) * 2013-03-11 2015-10-01 Elim Biopharmaceuticals, Inc. Enrichment and next generation sequencing of total nucleic acid comprising both genomic DNA and cDNA
EP2971152B1 (en) 2013-03-15 2018-08-01 The Board Of Trustees Of The Leland Stanford Junior University Identification and use of circulating nucleic acid tumor markers
JP6625045B2 (ja) * 2013-04-05 2019-12-25 ミリアド・ジェネティックス・インコーポレイテッド 相同組換え欠損を評価するための方法および材料
AU2014262481A1 (en) 2013-05-10 2015-11-26 Foundation Medicine, Inc. Analysis of genetic variants
US9708657B2 (en) * 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
WO2015021080A2 (en) 2013-08-05 2015-02-12 Twist Bioscience Corporation De novo synthesized gene libraries
ES2660989T3 (es) 2013-12-28 2018-03-27 Guardant Health, Inc. Métodos y sistemas para detectar variantes genéticas
AU2015357573B2 (en) 2014-12-05 2022-04-07 Foundation Medicine, Inc. Multigene analysis of tumor samples
WO2017151524A1 (en) 2016-02-29 2017-09-08 Foundation Medicine, Inc. Methods and systems for evaluating tumor mutational burden
US9850523B1 (en) 2016-09-30 2017-12-26 Guardant Health, Inc. Methods for multi-resolution analysis of cell-free nucleic acids
BR112020024727A2 (pt) 2018-06-11 2021-03-23 Foundation Medicine, Inc. composições e métodos para avaliação de alterações genômicas

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EP4112738A1 (en) 2023-01-04
EP4112738B1 (en) 2024-07-24
US11959141B2 (en) 2024-04-16
JP6905934B2 (ja) 2021-07-21
CA2967447A1 (en) 2016-06-09
AU2015357573B2 (en) 2022-04-07
AU2015357573A1 (en) 2017-05-25
WO2016090273A1 (en) 2016-06-09
JP2021166532A (ja) 2021-10-21
US20170356053A1 (en) 2017-12-14
JP2018502563A (ja) 2018-02-01
EP3227464B1 (en) 2022-04-20
EP3227464A4 (en) 2018-10-31
EP3227464A1 (en) 2017-10-11
AU2022204826A1 (en) 2022-09-22
AU2022204826B2 (en) 2024-05-23
JP7245872B2 (ja) 2023-03-24

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