HK1225608A1 - 用於治療與異常腸胃運動有關的疾病的酸泵拮抗劑 - Google Patents

用於治療與異常腸胃運動有關的疾病的酸泵拮抗劑

Info

Publication number
HK1225608A1
HK1225608A1 HK16113855A HK16113855A HK1225608A1 HK 1225608 A1 HK1225608 A1 HK 1225608A1 HK 16113855 A HK16113855 A HK 16113855A HK 16113855 A HK16113855 A HK 16113855A HK 1225608 A1 HK1225608 A1 HK 1225608A1
Authority
HK
Hong Kong
Prior art keywords
treatment
diseases associated
acid pump
pump antagonist
abnormal gastrointestinal
Prior art date
Application number
HK16113855A
Other languages
English (en)
Inventor
Takahashi Nobuyuki
Koizumi Shinichi
Original Assignee
Raqualia Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raqualia Pharma Inc filed Critical Raqualia Pharma Inc
Publication of HK1225608A1 publication Critical patent/HK1225608A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK16113855A 2009-07-09 2016-12-05 用於治療與異常腸胃運動有關的疾病的酸泵拮抗劑 HK1225608A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009163182 2009-07-09
JP2009188464 2009-08-17

Publications (1)

Publication Number Publication Date
HK1225608A1 true HK1225608A1 (zh) 2017-09-15

Family

ID=43429307

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16113855A HK1225608A1 (zh) 2009-07-09 2016-12-05 用於治療與異常腸胃運動有關的疾病的酸泵拮抗劑

Country Status (12)

Country Link
US (1) US8648080B2 (zh)
EP (1) EP2452680B1 (zh)
JP (4) JP5802898B2 (zh)
KR (1) KR101605063B1 (zh)
CN (2) CN102470126A (zh)
BR (1) BRPI1013288A2 (zh)
CA (1) CA2765529C (zh)
ES (1) ES2767251T3 (zh)
HK (1) HK1225608A1 (zh)
MX (1) MX2012000275A (zh)
RU (1) RU2586276C2 (zh)
WO (1) WO2011004882A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3071206T3 (pl) 2013-11-22 2022-01-17 CL BioSciences LLC Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie
CN105708812A (zh) * 2014-12-02 2016-06-29 江苏柯菲平医药股份有限公司 一种5-(2-氟苯基)-n-甲基-1-(3-吡啶基磺酰基)-1h-吡咯-3-甲氨冻干粉针及其制备方法
KR101684053B1 (ko) * 2015-01-20 2016-12-08 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법
MA41850A (fr) 2015-03-31 2018-02-06 Takeda Pharmaceuticals Co Nouvelles utilisations pharmaceutiques
DK3305291T3 (da) 2015-06-08 2021-06-28 Hk Inno N Corp Anvendelser af benzimidazolderivat mod natligt syregennembrud
CN105078891B (zh) * 2015-08-20 2018-04-24 寿光富康制药有限公司 一种tak-438脂质体及其制备方法和应用
CN105168131B (zh) * 2015-09-17 2018-04-24 寿光富康制药有限公司 一种tak-438纳米乳的制备方法
CN106913859B (zh) * 2015-12-25 2021-05-11 中美华世通生物医药科技(武汉)股份有限公司 药物组合物及制备方法
CN105663096B (zh) * 2016-01-25 2019-06-14 南京济群医药科技股份有限公司 一种沃诺拉赞口腔速溶膜剂及其制备方法
KR101829706B1 (ko) 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 산부가염
JOP20190060A1 (ar) * 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1
CN112933091B (zh) * 2020-09-07 2023-01-06 天地恒一制药股份有限公司 一种抗胃酸类疾病的药物组合物及应用
UY39479A (es) * 2020-10-23 2021-11-30 Hk Inno N Corp Comprimido de desintegración oral que comprende compuesto derivado de benzimidazol y procedimiento de preparación del mismo
KR102648315B1 (ko) * 2021-12-08 2024-03-15 (주) 팜젠사이언스 벤즈이미다졸 유도체 화합물 및 이의 용도

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5996272A (ja) 1982-11-26 1984-06-02 Isuzu Motors Ltd 金属表面の強化層形成方法
TW282460B (zh) 1993-12-28 1996-08-01 Yamanouchi Pharma Co Ltd
JP2896532B2 (ja) 1994-08-13 1999-05-31 ユーハン コーポレーション 新規なピリミジン誘導体およびその製造方法
SE9801526D0 (sv) 1998-04-29 1998-04-29 Astra Ab New compounds
SE9802794D0 (sv) 1998-08-21 1998-08-21 Astra Ab New compounds
SE9802793D0 (sv) 1998-08-21 1998-08-21 Astra Ab New compounds
GEP20032926B (en) 1998-09-23 2003-03-25 Altana Pharma Ag Tetrahydropyridoethers
WO2000026217A1 (en) 1998-11-03 2000-05-11 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazonaphthyridines
KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
TWI287014B (en) 1999-06-15 2007-09-21 Sankyo Co Optically active pyrrolopyridazine compound
CA2404474A1 (en) 2000-03-29 2001-10-04 Altana Pharma Ag Prodrugs of imidazopyridine derivatives
EP1334971A4 (en) 2000-10-12 2004-05-12 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUNDS, METHOD FOR THE PRODUCTION AND USE THEREOF
KR20040023739A (ko) 2001-08-10 2004-03-18 알타나 파마 아게 삼환식 이미다조피리딘
SE0102808D0 (sv) 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
CA2506027A1 (en) 2002-11-19 2004-06-03 Altana Pharma Ag 8-substituted imidazopyridines
AR043063A1 (es) 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
AR043962A1 (es) 2003-04-04 2005-08-17 Altana Pharma Ag Compuestos derivados de bencimidazol, medicamentos que los contienen y su uso para preparar dichos medicamentos.
RS20050868A (en) 2003-05-27 2007-08-03 Altana Pharma Ag., Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
SE0301905D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
KR20060118421A (ko) * 2003-08-29 2006-11-23 다이노젠 파마세우티컬스, 인코포레이티드 위장 운동 장애의 치료에 유용한 조성물
EP1670795A1 (en) 2003-09-18 2006-06-21 ALTANA Pharma AG Pharmacologically active imidazo 4,5-c pyridines
AR046893A1 (es) 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
AR046941A1 (es) 2003-12-19 2006-01-04 Altana Pharma Ag Imidazopiridinas triciclicas y su uso como inhibidores de secrecion de acido gastrico
WO2005070927A2 (en) 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
WO2005077947A1 (en) 2004-02-18 2005-08-25 Altana Pharma Ag 1,2,4-triazolo[4,3-a]pyridines useful in the treatment of gastrointestinal disorders
KR20070009614A (ko) 2004-03-17 2007-01-18 알타나 파마 아게 7h-8,9-디히드로-피라노(2,3-c)이미다조(1,2-a)피리딘유도체 및 이의 위산 분비 억제제로서의 용도
AR048869A1 (es) 2004-04-26 2006-06-07 Altana Pharma Ag Bencimidazoles triciclicos
CA2568856A1 (en) 2004-06-09 2005-12-22 Altana Pharma Ag Substituted tricyclic benzimidazoles
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-c]피리딘 유도체 및 그의 제조방법
US7541366B2 (en) 2004-09-03 2009-06-02 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
CA2578880C (en) 2004-09-03 2013-01-29 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
WO2006037748A1 (en) 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
AR051041A1 (es) 2004-10-04 2006-12-13 Altana Pharma Ag Bencimidazoles triciclicos condensados
AR051375A1 (es) 2004-10-15 2007-01-10 Altana Pharma Ag Imidazopiridinas difluoro substituidas
WO2006061380A2 (en) 2004-12-09 2006-06-15 Altana Pharma Ag SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS INHIBITORS OF GASTRIC ACID SECRETION
KR101122376B1 (ko) 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
KR101137168B1 (ko) 2005-03-09 2012-04-19 주식회사유한양행 피롤로[2,3-d]피리다진 유도체 및 그의 제조방법
EP1863820A1 (en) 2005-03-24 2007-12-12 Nycomed GmbH Thioamide-substituted tricyclic benzimidazoles useful for the treatment of gastrointestinal diseases
US20080255358A1 (en) 2005-03-24 2008-10-16 Mark James Bamford Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases
WO2006100254A1 (en) 2005-03-24 2006-09-28 Nycomed Gmbh 6-thioamide substituted benzimidazoles
AU2006243255A1 (en) 2005-04-29 2006-11-09 Nycomed Gmbh Mutual prodrug compounds for use us antiinflammatory agents with gastrointestinal protective activity
AR057061A1 (es) 2005-06-16 2007-11-14 Altana Pharma Ag Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos
CA2612112A1 (en) 2005-06-22 2006-12-28 Nycomed Gmbh Process for the production of intermediates for the preparation of tricyclic benzimidazoles
GB0513423D0 (en) 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
AU2006283876A1 (en) 2005-08-22 2007-03-01 Nycomed Gmbh Isotopically substituted benzimidazole derivatives
RS52473B9 (sr) 2005-08-30 2019-07-31 Takeda Pharmaceuticals Co 1-heterociklilsulfonil, 2-aminometil, 5-(hetero-)aril supstituisani derivati 1-h-pirola kao inhibitori sekrecije kiseline
US7776873B2 (en) 2005-12-01 2010-08-17 Yuhan Corporation Method for treating damage to gastric mucosa
BRPI0620081B8 (pt) * 2005-12-19 2021-05-25 Pfizer composto e composição farmacêutica.
US7994205B2 (en) 2006-03-31 2011-08-09 Takeda Pharmaceutical Company Limited Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors
WO2008015196A1 (en) 2006-07-31 2008-02-07 Nycomed Gmbh 5-,7-bis-substituted imidazo[1,2-a]pyridines
BRPI0717102A2 (pt) 2006-09-21 2013-10-29 Raqualia Pharma Inc Derivados de benzimidazol como inibidores seletivos de bomba de ácido
WO2008058990A1 (en) 2006-11-16 2008-05-22 Nycomed Gmbh 7,7-disubstituted pyrano-[2,3-c]-imidazo-[1,2-a]-pyridine derivatives and their use as gastric acid secretion inhibitors
WO2008071765A1 (en) 2006-12-14 2008-06-19 Nycomed Gmbh Pharmaceutically active spiro-substituted benzimidazole derivatives
WO2008071766A2 (en) 2006-12-14 2008-06-19 Nycomed Gmbh Spiro-indene substituted imidazonaphythyridine and pyranoimidazopyridine derivatives as inhibitors of gastric acid secretion
WO2008084067A2 (en) 2007-01-12 2008-07-17 Nycomed Gmbh Pharmaceutically active dihydrobenzofurane-substituted benzimidazole derivatives
WO2008095912A2 (en) 2007-02-06 2008-08-14 Nycomed Gmbh Enantiopure pharmacologically active tricyclic benzimidazoles
US8933105B2 (en) 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
WO2008151927A2 (en) 2007-06-15 2008-12-18 Nycomed Gmbh 6-n-substituted benz imidazole derivatives as acid pump antagonists
KR101558011B1 (ko) 2007-09-28 2015-10-06 다케다 야쿠힌 고교 가부시키가이샤 양성자 펌프 억제제로서의 5-원 이종원자고리 화합물
KR101559597B1 (ko) 2007-09-28 2015-10-12 다케다 야쿠힌 고교 가부시키가이샤 5―원 헤테로시클릭 화합물

Also Published As

Publication number Publication date
JP5978447B2 (ja) 2016-08-24
RU2586276C2 (ru) 2016-06-10
EP2452680B1 (en) 2019-12-18
KR20120052269A (ko) 2012-05-23
JP5802898B2 (ja) 2015-11-04
CA2765529C (en) 2017-02-07
JP2016166255A (ja) 2016-09-15
EP2452680A1 (en) 2012-05-16
RU2012104533A (ru) 2013-08-20
US8648080B2 (en) 2014-02-11
CN105919998A (zh) 2016-09-07
JPWO2011004882A1 (ja) 2012-12-20
KR101605063B1 (ko) 2016-03-21
WO2011004882A1 (ja) 2011-01-13
JP2013144719A (ja) 2013-07-25
EP2452680A4 (en) 2013-12-04
BRPI1013288A2 (pt) 2016-03-29
US20120115820A1 (en) 2012-05-10
JP2015038140A (ja) 2015-02-26
CN102470126A (zh) 2012-05-23
MX2012000275A (es) 2012-02-08
JP5699309B2 (ja) 2015-04-08
ES2767251T3 (es) 2020-06-17
CN105919998B (zh) 2021-08-24
CA2765529A1 (en) 2011-01-13
JP6212765B2 (ja) 2017-10-18

Similar Documents

Publication Publication Date Title
HK1225608A1 (zh) 用於治療與異常腸胃運動有關的疾病的酸泵拮抗劑
ZA201301601B (en) Treatment of diseases
GB0910003D0 (en) Novel compounds for the treatment of neurodegenerative diseases
EP2417448A4 (en) BIOMARKERS FOR MONITORING THE TREATMENT OF NEUROPSYCHIATRIC ILLNESSES
EP2613786A4 (en) TREATMENT OF DISEASES
GB0915515D0 (en) Treatment of vasculoproliferative conditions
GB0908193D0 (en) Treatment of disease state
EP2649456A4 (en) BIOMARKERS FOR MONITORING THE TREATMENT OF NEUROPSYCHIATRIC ILLNESSES
EP2414824A4 (en) BIOMARKERS FOR MONITORING THE TREATMENT OF NEUROPSYCHIATRIC ILLNESSES
EP2623494A4 (en) AGENT FOR THE TREATMENT OF OCULAR DISEASES
GB0906159D0 (en) Drug combination for the treatment of proteostatic diseases
HK1176870A1 (zh) 疾病的治療方法
EP2704723A4 (en) TREATMENT OF POLYCYSTIC DISEASES
EP2608804A4 (en) TREATMENT OF RENAL DISEASES
EP2544686A4 (en) COMBINED METHODS FOR THE TREATMENT OF DISEASES
EP2416803A4 (en) NEW METHODS OF TREATING INFLAMMATORY DISEASES
PL2477656T3 (pl) Leczenie stanów neurologicznych
EP2454229A4 (en) AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN
GB0903858D0 (en) Diagnosis of disease
EP2500029A4 (en) THERAPEUTIC AGENT FOR DISEASES OF THE STOMACH DARM TRAKTS
GB0908666D0 (en) Treatment of proteostatic disease
GB201002841D0 (en) Treatment of inflammatory respiratory disease
GB0903273D0 (en) Manufacture of insoluble drugs
GB0922675D0 (en) Treatment for gastrointestinal conditions
GB0921957D0 (en) Treatment for gastrointestinal conditions