HK1223884A1 - 具有多個或可調節位置的攪拌器設計的生物反應器 - Google Patents

具有多個或可調節位置的攪拌器設計的生物反應器

Info

Publication number
HK1223884A1
HK1223884A1 HK16112251.1A HK16112251A HK1223884A1 HK 1223884 A1 HK1223884 A1 HK 1223884A1 HK 16112251 A HK16112251 A HK 16112251A HK 1223884 A1 HK1223884 A1 HK 1223884A1
Authority
HK
Hong Kong
Prior art keywords
bioreactors
adjustable
position agitator
agitator designs
designs
Prior art date
Application number
HK16112251.1A
Other languages
English (en)
Inventor
Ekta Mahajan
Kelsey Dent
Edward Chan
Terry Hudson
Neria Daniel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1223884A1 publication Critical patent/HK1223884A1/zh

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/88Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with a separate receptacle-stirrer unit that is adapted to be coupled to a drive mechanism
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/453Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
    • B01F33/4535Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements using a stud for supporting the stirring element
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/32005Type of drive
    • B01F35/3204Motor driven, i.e. by means of an electric or IC motor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/321Disposition of the drive
    • B01F35/3213Disposition of the drive at the lower side of the axis, e.g. driving the stirrer from the bottom of a receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/321Disposition of the drive
    • B01F35/3214Disposition of the drive at the upper side of the axis, e.g. driving the stirrer from the top of a receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/42Clamping or holding arrangements for mounting receptacles on mixing devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50Mixing receptacles
    • B01F35/513Flexible receptacles, e.g. bags supported by rigid containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F35/93Heating or cooling systems arranged inside the receptacle
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/26Constructional details, e.g. recesses, hinges flexible
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/28Constructional details, e.g. recesses, hinges disposable or single use
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F2035/99Heating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
HK16112251.1A 2013-09-16 2016-10-25 具有多個或可調節位置的攪拌器設計的生物反應器 HK1223884A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361878516P 2013-09-16 2013-09-16
PCT/US2014/055674 WO2015039034A1 (en) 2013-09-16 2014-09-15 Bioreactors with multiple or adjustable -position agitator designs

Publications (1)

Publication Number Publication Date
HK1223884A1 true HK1223884A1 (zh) 2017-08-11

Family

ID=52666381

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16112251.1A HK1223884A1 (zh) 2013-09-16 2016-10-25 具有多個或可調節位置的攪拌器設計的生物反應器

Country Status (15)

Country Link
US (2) US10563161B2 (zh)
EP (1) EP3046644A4 (zh)
JP (2) JP6542232B2 (zh)
KR (1) KR102338172B1 (zh)
CN (2) CN110172406B (zh)
AR (2) AR097670A1 (zh)
AU (3) AU2014318426B2 (zh)
CA (1) CA2922967C (zh)
HK (1) HK1223884A1 (zh)
IL (1) IL244352B (zh)
MX (1) MX2016003365A (zh)
RU (1) RU2704229C2 (zh)
SG (2) SG11201601940PA (zh)
WO (1) WO2015039034A1 (zh)
ZA (1) ZA201601698B (zh)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014318426B2 (en) 2013-09-16 2019-01-24 Genentech, Inc. Bioreactors with multiple or adjustable -position agitator designs
DE102015007060B4 (de) 2015-06-02 2023-12-14 Sartorius Stedim Biotech Gmbh Bioreaktorsystem und Verfahren
DE102015007061B4 (de) * 2015-06-02 2023-12-14 Sartorius Stedim Biotech Gmbh System, Vorrichtung und Verfahren zum Aufnehmen eines Einwegbeutels
FR3039776B1 (fr) 2015-08-03 2017-08-25 Sartorius Stedim Fmt Sas Procede d'assemblage d'un recipient-melangeur comprenant un arbre telescopique.
GB201600319D0 (en) * 2016-01-08 2016-02-24 Ge Healthcare Bio Sciences Ab A rigid housing for holding a flexible bag
DE102016003136B4 (de) * 2016-03-15 2024-01-11 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur Aufnahme eines Einwegbehälters
DE102016008655B4 (de) * 2016-07-15 2024-01-25 Sartorius Stedim Biotech Gmbh Anlage für biotechnologische Anwendungen mit Träger zur Lagerung von Komponenten
CN208414400U (zh) * 2016-11-01 2019-01-22 生命科技股份有限公司 液体混合***
CN108070513A (zh) * 2016-11-17 2018-05-25 天津奥华通航科技有限公司 一种生物发酵自动翻料机构
WO2018122247A1 (en) * 2016-12-29 2018-07-05 Ge Healthcare Bio-Sciences Ab Housing for holding a flexible bioprocess bag
DE102017130093B4 (de) * 2017-12-15 2019-11-21 Sartorius Stedim Biotech Gmbh Vorrichtungsanordnung für die Durchführung wenigstens einer Grundoperation in einem biopharmazeutischen Prozess
CN111615553A (zh) 2018-01-17 2020-09-01 生命技术公司 可配置流体混合***壳体和支撑硬件
USD894377S1 (en) 2019-01-03 2020-08-25 Life Technologies Corporation Tube management assembly
GB201901494D0 (en) * 2019-02-04 2019-03-27 Innospec Ltd Polymeric materials
GB201901503D0 (en) 2019-02-04 2019-03-27 Innospec Ltd Chemical reactions
GB201901499D0 (en) * 2019-02-04 2019-03-27 Innospec Ltd Polymeric materials
GB201901496D0 (en) * 2019-02-04 2019-03-27 Innospec Ltd Chemical reactions
US20220243159A1 (en) * 2019-05-29 2022-08-04 Cytiva Sweden Ab Systems and Methods for Probe Angle Adjustment in Bioreactors
JP2022535611A (ja) * 2019-06-12 2022-08-09 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー バイオプロセスシステム、バイオプロセスシステムのための配管および構成要素の管理装置
US20220251491A1 (en) * 2019-06-24 2022-08-11 Global Life Sciences Solutions Usa Llc Bioreactor support system
CN110466059A (zh) * 2019-09-06 2019-11-19 中国二冶集团有限公司 一种人防工程建筑浇筑搅拌设备
KR20220113925A (ko) * 2019-09-27 2022-08-17 비더블유엑스티 아이소토프 테크놀로지 그룹, 인크. 화학 용기 교반기
EP4127127A1 (en) * 2020-03-27 2023-02-08 Broadley-James Corporation Single-use bioreactor assembly with integrated pump heads
JP6817677B1 (ja) * 2020-07-02 2021-01-20 佐竹化学機械工業株式会社 バイオリアクター、バイオリアクターの製造方法、および、バイオリアクターに用いられる使い捨てバッグ
KR20230038201A (ko) * 2020-07-15 2023-03-17 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 바이오프로세싱 시스템 및 바이오프로세싱 시스템용 튜빙 및 부품 관리 장치
US11998880B2 (en) * 2020-09-01 2024-06-04 Global Life Sciences Solutions Usa Llc Collapsible agitator assembly for a bioprocessing system
DE102020005550A1 (de) * 2020-09-10 2022-03-10 Sartorius Stedim Biotech Gmbh Bioreaktorsysteme sowie Verfahren zum Betreiben eines Bioprozesses
US20230093509A1 (en) * 2021-09-23 2023-03-23 Conecraft, Inc. Mixer with Single-Use Liner Conversion to Top-Mix Operation
DE102021127134A1 (de) * 2021-10-19 2023-04-20 TRI Thinking Research Instruments GmbH Bilderfassungsvorrichtung für einen transparenten Bioreaktor
CN114950212B (zh) * 2022-05-19 2024-04-12 博雅工道(北京)机器人科技有限公司 水下搅拌注浆***以及水下搅拌注浆方法
WO2024025825A1 (en) * 2022-07-25 2024-02-01 Mayo Foundation For Medical Education And Research Bioreactor systems and methods for electrically stimulating cells
WO2024044698A2 (en) * 2022-08-24 2024-02-29 Arizona Board Of Regents On Behalf Of The University Of Arizona Transformer bioreactor
JP7422925B1 (ja) 2023-07-19 2024-01-26 佐竹マルチミクス株式会社 バイオリアクター培養方法、及び、バイオリアクターの滅菌装置

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584103A (en) 1977-06-01 1981-02-04 Ranks Hovis Mcdougall Ltd Method and apparatus for promoting fermentation
JPS61104780A (ja) * 1984-10-29 1986-05-23 Hitachi Ltd 培養装置
KR0138254B1 (ko) * 1989-03-10 1998-04-27 니시오카 시게루 교반장치
US6758593B1 (en) 2000-10-09 2004-07-06 Levtech, Inc. Pumping or mixing system using a levitating magnetic element, related system components, and related methods
US7086778B2 (en) 2000-10-09 2006-08-08 Levtech, Inc. System using a levitating, rotating pumping or mixing element and related methods
US7762716B2 (en) * 2000-10-09 2010-07-27 Levtech, Inc. Mixing vessel with a fluid-agitating element supported by a roller bearing
US6837613B2 (en) 2001-04-10 2005-01-04 Levtech, Inc. Sterile fluid pumping or mixing system and related method
IL157188A (en) * 2001-02-06 2004-07-25 Levtech Inc Apparatus and method for mixing materials sealed in a container under sterile conditions
ATE477843T1 (de) 2001-10-03 2010-09-15 Levtech Inc Mischbehälter mit einer aufnahmevorrichtung für ein fluidbewegungselement
US6923567B2 (en) * 2002-04-12 2005-08-02 Hynetics Llc Mixing tank assembly
US8206973B2 (en) * 2003-09-04 2012-06-26 Gotohti.Com Inc Automated biological growth and dispensing system
WO2005068059A1 (en) 2004-01-07 2005-07-28 Levtech, Inc. Mixing bag with integral sparger and sensor receiver
JP2007534335A (ja) 2004-04-27 2007-11-29 バクスター・インターナショナル・インコーポレイテッド 攪拌タンク反応器システム
AU2005250500B2 (en) * 2004-06-04 2011-06-23 Global Life Sciences Solutions Usa Llc Disposable bioreactor systems and methods
US7879599B2 (en) 2005-04-22 2011-02-01 Hyclone Laboratories, Inc. Tube ports and related container systems
US7682067B2 (en) * 2005-04-22 2010-03-23 Hyclone Laboratories, Inc. Mixing systems and related mixers
US20090142627A1 (en) 2005-09-28 2009-06-04 Tatsuo Shimomura Biological Power Generator, and Method of Treating Organic Solid Pollutant-Containing Waste, a Method of Treating Organic Polymeric Substance-Containing Wastewater, a Method of Treating Organic Substance-Containing Wastewater, as Well as Apparatuses for Implementing These Treatment Methods
US8790913B2 (en) 2005-10-26 2014-07-29 Pbs Biotech, Inc. Methods of using pneumatic bioreactors
DE102006020461B3 (de) * 2006-04-28 2007-10-04 Sartorius Biotech Gmbh Behälter mit flexiblen Wänden
US20080068920A1 (en) 2006-06-16 2008-03-20 Xcellerex, Inc. Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors
US8822209B2 (en) * 2007-07-12 2014-09-02 Brooks Automation, Inc. Disposable spinner flask
US7832922B2 (en) * 2007-11-30 2010-11-16 Levitronix Gmbh Mixing apparatus and container for such
US8690418B2 (en) 2008-03-19 2014-04-08 Sartorius Stedim Biotech Gmbh Method of mixing
US8505315B2 (en) 2008-04-15 2013-08-13 Uchicago Argonne, Llc Enhanced integrated operation blender based sterile medical ice slurry production device
EP2279039A2 (de) * 2008-04-17 2011-02-02 Sartorius Stedim Biotech GmbH Flexibler beutel mit einer mischvorrichtung
US8381780B2 (en) 2008-05-22 2013-02-26 Xcellerex, Inc. Lift and support assemblies and methods for collapsible bag containers of vessels and bioreactors
WO2009151514A1 (en) * 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
EP2216395A1 (en) * 2009-02-09 2010-08-11 Lonza Biologics plc. Bioreactor for the cultivation of mammalian cells
FR2943355B1 (fr) 2009-03-18 2011-04-08 Sartorius Stedim Biotech Sa Recipient-melangeur avec palier d'arbre en partie superieure
FR2943560B1 (fr) * 2009-03-24 2011-05-27 Jean Pascal Zambaux Bioreacteur jetable et systeme d'agitation a usage unique
US8492135B2 (en) * 2009-04-03 2013-07-23 Tissue Growth Technologies Corporation Deformable transportable bioreactor chamber
US8506198B2 (en) 2010-02-01 2013-08-13 Hyclone Laboratories, Inc. Self aligning coupling for mixing system
US8455242B2 (en) * 2010-02-22 2013-06-04 Hyclone Laboratories, Inc. Mixing system with condenser
EP2544809B1 (en) 2010-03-09 2014-10-08 EMD Millipore Corporation Process bag container with sensors
RU98002U1 (ru) * 2010-05-24 2010-09-27 Государственное образовательное учреждение высшего профессионального образования "Восточно-Сибирский государственный технологический университет" Аппарат для культивирования микроорганизмов
JP2013542420A (ja) 2010-09-23 2013-11-21 エクセレレックス インク. 単回使用のスラリー化−クロマトグラフィーシステム
US9193945B2 (en) * 2010-12-23 2015-11-24 Uts Biogastechnik Gmbh Biogas plant and service device for a biogas plant
US9314751B2 (en) * 2011-01-07 2016-04-19 Life Technologies Corporation Methods and apparatus for mixing and shipping fluids
US8608369B2 (en) * 2011-01-07 2013-12-17 Hyclone Laboratories, Inc. Methods and systems for heating and mixing fluids
US9550157B2 (en) * 2011-09-16 2017-01-24 Ge Heathcare Bio-Sciences Corp Single-use mixing and bioreactor systems
EP3922712A3 (en) * 2011-10-25 2022-03-09 Life Technologies Corporation Fluid mixing systems with adjustable mixing element
AU2014318426B2 (en) 2013-09-16 2019-01-24 Genentech, Inc. Bioreactors with multiple or adjustable -position agitator designs

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RU2704229C2 (ru) 2019-10-24
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