SG11201601940PA - Bioreactors with multiple or adjustable -position agitator designs - Google Patents

Bioreactors with multiple or adjustable -position agitator designs

Info

Publication number
SG11201601940PA
SG11201601940PA SG11201601940PA SG11201601940PA SG11201601940PA SG 11201601940P A SG11201601940P A SG 11201601940PA SG 11201601940P A SG11201601940P A SG 11201601940PA SG 11201601940P A SG11201601940P A SG 11201601940PA SG 11201601940P A SG11201601940P A SG 11201601940PA
Authority
SG
Singapore
Prior art keywords
bioreactors
adjustable
position agitator
agitator designs
designs
Prior art date
Application number
SG11201601940PA
Inventor
Ekta Mahajan
Kelsey Dent
Edward Chan
Terry Hudson
Neria Daniel
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG11201601940PA publication Critical patent/SG11201601940PA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/88Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with a separate receptacle-stirrer unit that is adapted to be coupled to a drive mechanism
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/453Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
    • B01F33/4535Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements using a stud for supporting the stirring element
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/32005Type of drive
    • B01F35/3204Motor driven, i.e. by means of an electric or IC motor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/321Disposition of the drive
    • B01F35/3213Disposition of the drive at the lower side of the axis, e.g. driving the stirrer from the bottom of a receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32Driving arrangements
    • B01F35/321Disposition of the drive
    • B01F35/3214Disposition of the drive at the upper side of the axis, e.g. driving the stirrer from the top of a receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/40Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
    • B01F35/42Clamping or holding arrangements for mounting receptacles on mixing devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50Mixing receptacles
    • B01F35/513Flexible receptacles, e.g. bags supported by rigid containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F35/93Heating or cooling systems arranged inside the receptacle
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/26Constructional details, e.g. recesses, hinges flexible
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/28Constructional details, e.g. recesses, hinges disposable or single use
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/48Holding appliances; Racks; Supports
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/90Heating or cooling systems
    • B01F2035/99Heating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
SG11201601940PA 2013-09-16 2014-09-15 Bioreactors with multiple or adjustable -position agitator designs SG11201601940PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361878516P 2013-09-16 2013-09-16
PCT/US2014/055674 WO2015039034A1 (en) 2013-09-16 2014-09-15 Bioreactors with multiple or adjustable -position agitator designs

Publications (1)

Publication Number Publication Date
SG11201601940PA true SG11201601940PA (en) 2016-04-28

Family

ID=52666381

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201601940PA SG11201601940PA (en) 2013-09-16 2014-09-15 Bioreactors with multiple or adjustable -position agitator designs
SG10201910334WA SG10201910334WA (en) 2013-09-16 2014-09-15 Bioreactors with multiple or adjustable -position agitator designs

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201910334WA SG10201910334WA (en) 2013-09-16 2014-09-15 Bioreactors with multiple or adjustable -position agitator designs

Country Status (15)

Country Link
US (2) US10563161B2 (en)
EP (1) EP3046644A4 (en)
JP (2) JP6542232B2 (en)
KR (1) KR102338172B1 (en)
CN (2) CN110172406B (en)
AR (2) AR097670A1 (en)
AU (3) AU2014318426B2 (en)
CA (1) CA2922967C (en)
HK (1) HK1223884A1 (en)
IL (1) IL244352B (en)
MX (1) MX2016003365A (en)
RU (1) RU2704229C2 (en)
SG (2) SG11201601940PA (en)
WO (1) WO2015039034A1 (en)
ZA (1) ZA201601698B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014318426B2 (en) 2013-09-16 2019-01-24 Genentech, Inc. Bioreactors with multiple or adjustable -position agitator designs
DE102015007060B4 (en) 2015-06-02 2023-12-14 Sartorius Stedim Biotech Gmbh Bioreactor system and method
DE102015007061B4 (en) * 2015-06-02 2023-12-14 Sartorius Stedim Biotech Gmbh System, device and method for receiving a disposable bag
FR3039776B1 (en) 2015-08-03 2017-08-25 Sartorius Stedim Fmt Sas METHOD FOR ASSEMBLING A CONTAINER-MIXER COMPRISING A TELESCOPIC TREE
GB201600319D0 (en) * 2016-01-08 2016-02-24 Ge Healthcare Bio Sciences Ab A rigid housing for holding a flexible bag
DE102016003136B4 (en) * 2016-03-15 2024-01-11 Sartorius Stedim Biotech Gmbh Device and method for holding a disposable container
DE102016008655B4 (en) * 2016-07-15 2024-01-25 Sartorius Stedim Biotech Gmbh Plant for biotechnological applications with a carrier for storing components
CN208414400U (en) * 2016-11-01 2019-01-22 生命科技股份有限公司 Mixing system
CN108070513A (en) * 2016-11-17 2018-05-25 天津奥华通航科技有限公司 A kind of biofermentation automatic overturning mechanism
WO2018122247A1 (en) * 2016-12-29 2018-07-05 Ge Healthcare Bio-Sciences Ab Housing for holding a flexible bioprocess bag
DE102017130093B4 (en) * 2017-12-15 2019-11-21 Sartorius Stedim Biotech Gmbh Device arrangement for carrying out at least one basic operation in a biopharmaceutical process
CN111615553A (en) 2018-01-17 2020-09-01 生命技术公司 Configurable fluid mixing system housing and support hardware
USD894377S1 (en) 2019-01-03 2020-08-25 Life Technologies Corporation Tube management assembly
GB201901494D0 (en) * 2019-02-04 2019-03-27 Innospec Ltd Polymeric materials
GB201901503D0 (en) 2019-02-04 2019-03-27 Innospec Ltd Chemical reactions
GB201901499D0 (en) * 2019-02-04 2019-03-27 Innospec Ltd Polymeric materials
GB201901496D0 (en) * 2019-02-04 2019-03-27 Innospec Ltd Chemical reactions
US20220243159A1 (en) * 2019-05-29 2022-08-04 Cytiva Sweden Ab Systems and Methods for Probe Angle Adjustment in Bioreactors
JP2022535611A (en) * 2019-06-12 2022-08-09 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー Bioprocess Systems, Piping and Component Management Devices for Bioprocess Systems
US20220251491A1 (en) * 2019-06-24 2022-08-11 Global Life Sciences Solutions Usa Llc Bioreactor support system
CN110466059A (en) * 2019-09-06 2019-11-19 中国二冶集团有限公司 A kind of civil air defense constructions and installations building pours mixing plant
KR20220113925A (en) * 2019-09-27 2022-08-17 비더블유엑스티 아이소토프 테크놀로지 그룹, 인크. chemical vessel agitator
EP4127127A1 (en) * 2020-03-27 2023-02-08 Broadley-James Corporation Single-use bioreactor assembly with integrated pump heads
JP6817677B1 (en) * 2020-07-02 2021-01-20 佐竹化学機械工業株式会社 Bioreactors, bioreactor manufacturing methods, and disposable bags used in bioreactors
KR20230038201A (en) * 2020-07-15 2023-03-17 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 Tubing and parts management devices for bioprocessing systems and bioprocessing systems
US11998880B2 (en) * 2020-09-01 2024-06-04 Global Life Sciences Solutions Usa Llc Collapsible agitator assembly for a bioprocessing system
DE102020005550A1 (en) * 2020-09-10 2022-03-10 Sartorius Stedim Biotech Gmbh Bioreactor systems and methods for operating a bioprocess
US20230093509A1 (en) * 2021-09-23 2023-03-23 Conecraft, Inc. Mixer with Single-Use Liner Conversion to Top-Mix Operation
DE102021127134A1 (en) * 2021-10-19 2023-04-20 TRI Thinking Research Instruments GmbH Image acquisition device for a transparent bioreactor
CN114950212B (en) * 2022-05-19 2024-04-12 博雅工道(北京)机器人科技有限公司 Underwater stirring grouting system and underwater stirring grouting method
WO2024025825A1 (en) * 2022-07-25 2024-02-01 Mayo Foundation For Medical Education And Research Bioreactor systems and methods for electrically stimulating cells
WO2024044698A2 (en) * 2022-08-24 2024-02-29 Arizona Board Of Regents On Behalf Of The University Of Arizona Transformer bioreactor
JP7422925B1 (en) 2023-07-19 2024-01-26 佐竹マルチミクス株式会社 Bioreactor culture method and bioreactor sterilization device

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584103A (en) 1977-06-01 1981-02-04 Ranks Hovis Mcdougall Ltd Method and apparatus for promoting fermentation
JPS61104780A (en) * 1984-10-29 1986-05-23 Hitachi Ltd Cultivator
KR0138254B1 (en) * 1989-03-10 1998-04-27 니시오카 시게루 Stirrer
US6758593B1 (en) 2000-10-09 2004-07-06 Levtech, Inc. Pumping or mixing system using a levitating magnetic element, related system components, and related methods
US7086778B2 (en) 2000-10-09 2006-08-08 Levtech, Inc. System using a levitating, rotating pumping or mixing element and related methods
US7762716B2 (en) * 2000-10-09 2010-07-27 Levtech, Inc. Mixing vessel with a fluid-agitating element supported by a roller bearing
US6837613B2 (en) 2001-04-10 2005-01-04 Levtech, Inc. Sterile fluid pumping or mixing system and related method
IL157188A (en) * 2001-02-06 2004-07-25 Levtech Inc Apparatus and method for mixing materials sealed in a container under sterile conditions
ATE477843T1 (en) 2001-10-03 2010-09-15 Levtech Inc MIXING CONTAINER WITH A RECEIVING DEVICE FOR A FLUID MOVEMENT ELEMENT
US6923567B2 (en) * 2002-04-12 2005-08-02 Hynetics Llc Mixing tank assembly
US8206973B2 (en) * 2003-09-04 2012-06-26 Gotohti.Com Inc Automated biological growth and dispensing system
WO2005068059A1 (en) 2004-01-07 2005-07-28 Levtech, Inc. Mixing bag with integral sparger and sensor receiver
JP2007534335A (en) 2004-04-27 2007-11-29 バクスター・インターナショナル・インコーポレイテッド Stirred tank reactor system
AU2005250500B2 (en) * 2004-06-04 2011-06-23 Global Life Sciences Solutions Usa Llc Disposable bioreactor systems and methods
US7879599B2 (en) 2005-04-22 2011-02-01 Hyclone Laboratories, Inc. Tube ports and related container systems
US7682067B2 (en) * 2005-04-22 2010-03-23 Hyclone Laboratories, Inc. Mixing systems and related mixers
US20090142627A1 (en) 2005-09-28 2009-06-04 Tatsuo Shimomura Biological Power Generator, and Method of Treating Organic Solid Pollutant-Containing Waste, a Method of Treating Organic Polymeric Substance-Containing Wastewater, a Method of Treating Organic Substance-Containing Wastewater, as Well as Apparatuses for Implementing These Treatment Methods
US8790913B2 (en) 2005-10-26 2014-07-29 Pbs Biotech, Inc. Methods of using pneumatic bioreactors
DE102006020461B3 (en) * 2006-04-28 2007-10-04 Sartorius Biotech Gmbh Flexible wall liquid container includes an agitator with through-wall magnetic coupled drive for longitudinal shaft movement from an external driver
US20080068920A1 (en) 2006-06-16 2008-03-20 Xcellerex, Inc. Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors
US8822209B2 (en) * 2007-07-12 2014-09-02 Brooks Automation, Inc. Disposable spinner flask
US7832922B2 (en) * 2007-11-30 2010-11-16 Levitronix Gmbh Mixing apparatus and container for such
US8690418B2 (en) 2008-03-19 2014-04-08 Sartorius Stedim Biotech Gmbh Method of mixing
US8505315B2 (en) 2008-04-15 2013-08-13 Uchicago Argonne, Llc Enhanced integrated operation blender based sterile medical ice slurry production device
EP2279039A2 (en) * 2008-04-17 2011-02-02 Sartorius Stedim Biotech GmbH Flexible bag having a mixing device
US8381780B2 (en) 2008-05-22 2013-02-26 Xcellerex, Inc. Lift and support assemblies and methods for collapsible bag containers of vessels and bioreactors
WO2009151514A1 (en) * 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
EP2216395A1 (en) * 2009-02-09 2010-08-11 Lonza Biologics plc. Bioreactor for the cultivation of mammalian cells
FR2943355B1 (en) 2009-03-18 2011-04-08 Sartorius Stedim Biotech Sa RECIPIENT-MIXER WITH SHAFT BEARING IN SUPERIOR PART
FR2943560B1 (en) * 2009-03-24 2011-05-27 Jean Pascal Zambaux DISPOSABLE BIOREACTOR AND AGITATOR SYSTEM FOR SINGLE USE
US8492135B2 (en) * 2009-04-03 2013-07-23 Tissue Growth Technologies Corporation Deformable transportable bioreactor chamber
US8506198B2 (en) 2010-02-01 2013-08-13 Hyclone Laboratories, Inc. Self aligning coupling for mixing system
US8455242B2 (en) * 2010-02-22 2013-06-04 Hyclone Laboratories, Inc. Mixing system with condenser
EP2544809B1 (en) 2010-03-09 2014-10-08 EMD Millipore Corporation Process bag container with sensors
RU98002U1 (en) * 2010-05-24 2010-09-27 Государственное образовательное учреждение высшего профессионального образования "Восточно-Сибирский государственный технологический университет" DEVICE FOR CULTIVATION OF MICROORGANISMS
JP2013542420A (en) 2010-09-23 2013-11-21 エクセレレックス インク. Single use slurrying-chromatography system
US9193945B2 (en) * 2010-12-23 2015-11-24 Uts Biogastechnik Gmbh Biogas plant and service device for a biogas plant
US9314751B2 (en) * 2011-01-07 2016-04-19 Life Technologies Corporation Methods and apparatus for mixing and shipping fluids
US8608369B2 (en) * 2011-01-07 2013-12-17 Hyclone Laboratories, Inc. Methods and systems for heating and mixing fluids
US9550157B2 (en) * 2011-09-16 2017-01-24 Ge Heathcare Bio-Sciences Corp Single-use mixing and bioreactor systems
EP3922712A3 (en) * 2011-10-25 2022-03-09 Life Technologies Corporation Fluid mixing systems with adjustable mixing element
AU2014318426B2 (en) 2013-09-16 2019-01-24 Genentech, Inc. Bioreactors with multiple or adjustable -position agitator designs

Also Published As

Publication number Publication date
US10563161B2 (en) 2020-02-18
CN110172406A (en) 2019-08-27
CN105531004A (en) 2016-04-27
CN110172406B (en) 2023-08-08
RU2704229C2 (en) 2019-10-24
AR097670A1 (en) 2016-04-06
JP2019146575A (en) 2019-09-05
AU2021203273A1 (en) 2021-06-17
JP2016529918A (en) 2016-09-29
NZ717525A (en) 2021-02-26
RU2016114510A3 (en) 2018-03-21
AR118138A2 (en) 2021-09-22
JP6542232B2 (en) 2019-07-10
WO2015039034A1 (en) 2015-03-19
JP6803943B2 (en) 2020-12-23
IL244352B (en) 2021-06-30
CN105531004B (en) 2019-06-14
RU2016114510A (en) 2017-10-23
SG10201910334WA (en) 2020-01-30
EP3046644A1 (en) 2016-07-27
US20160304824A1 (en) 2016-10-20
MX2016003365A (en) 2016-06-24
IL244352A0 (en) 2016-04-21
AU2019202902A1 (en) 2019-05-23
CA2922967A1 (en) 2015-03-19
HK1223884A1 (en) 2017-08-11
NZ756995A (en) 2021-02-26
CA2922967C (en) 2022-05-03
US11155777B2 (en) 2021-10-26
AU2014318426B2 (en) 2019-01-24
KR20160055255A (en) 2016-05-17
ZA201601698B (en) 2019-06-26
EP3046644A4 (en) 2017-08-09
US20200131463A1 (en) 2020-04-30
KR102338172B1 (en) 2021-12-09

Similar Documents

Publication Publication Date Title
HK1223884A1 (en) Bioreactors with multiple or adjustable-position agitator designs
HRP20182063T1 (en) Rhizomania-resistant gene
EP2971057A4 (en) Bioreactor system
ZA201603992B (en) Agitator impeller arrangement
HUE063222T2 (en) Photobioreactor
GB201320417D0 (en) Mixing reactors
GB201304810D0 (en) Assay
PL2970845T3 (en) Bioreactor
SG11201600072SA (en) Culture vessel
GB2514842B (en) Agitator assembly
GB201321838D0 (en) Pulse fermentation
IL245913A0 (en) Beta-glucan assay methods
IL240204A0 (en) Bioreactor suspension
EP2956922A4 (en) Sign with sign elements
GB201401001D0 (en) Enzyme function probes
TWM475867U (en) Caring bottle with mixing function
ZA201409312B (en) Improved aeration
GB201313364D0 (en) Anaerobic digester
GB201316003D0 (en) Bioreactor lid
GB201308905D0 (en) Cell culture
GB201306488D0 (en) Cell culture
AU2013900317A0 (en) Bioreactor
AU2014276609A1 (en) Agitator assembly
GB201318464D0 (en) Modified enzymes
GB201303355D0 (en) Zippy Doodah