HK1220459A1 - 激酶抑制劑 - Google Patents

激酶抑制劑

Info

Publication number
HK1220459A1
HK1220459A1 HK16108561.4A HK16108561A HK1220459A1 HK 1220459 A1 HK1220459 A1 HK 1220459A1 HK 16108561 A HK16108561 A HK 16108561A HK 1220459 A1 HK1220459 A1 HK 1220459A1
Authority
HK
Hong Kong
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
HK16108561.4A
Other languages
English (en)
Inventor
．阿爾卡拉斯
．赫爾利
．克裡蒂蘭德
．詹寧斯
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of HK1220459A1 publication Critical patent/HK1220459A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/02—Formic acid
    • C07C53/06—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
HK16108561.4A 2013-06-06 2016-07-19 激酶抑制劑 HK1220459A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13170937 2013-06-06
PCT/EP2014/061683 WO2014195402A1 (en) 2013-06-06 2014-06-05 Kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1220459A1 true HK1220459A1 (zh) 2017-05-05

Family

ID=48569997

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108561.4A HK1220459A1 (zh) 2013-06-06 2016-07-19 激酶抑制劑

Country Status (10)

Country Link
US (2) US9181242B2 (zh)
EP (1) EP3004097B1 (zh)
KR (1) KR20160018567A (zh)
CN (1) CN105377847A (zh)
AR (1) AR096532A1 (zh)
BR (1) BR112015029970A2 (zh)
CA (1) CA2914432A1 (zh)
HK (1) HK1220459A1 (zh)
RU (1) RU2015151886A (zh)
WO (1) WO2014195402A1 (zh)

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US9573949B2 (en) * 2013-06-06 2017-02-21 Chiesi Farmaceutici S.P.A. Derivatives of [1, 2, 4] triazolo [4, 3-a] pyridine as P38—MAP kinase inhibitors
EP3394059B1 (en) 2015-12-23 2020-11-25 Chiesi Farmaceutici S.p.A. 1-(3-tert-butyl-phenyl)-3-(4-([1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro- naphthalen-1-yl)-urea derivatives and their use as p38 mapk inhibitors
WO2017108736A1 (en) 2015-12-23 2017-06-29 Chiesi Farmaceutici S.P.A. N-[3-(3-{4-[[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl} -ureido)-phenyl]-methanesulfonamide derivatives and their use as p38 mapk inhibitors
US10364245B2 (en) 2017-06-07 2019-07-30 Chiesi Farmaceutici S.P.A. Kinase inhibitors
EP4159212A1 (en) 2017-10-05 2023-04-05 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
CN108424372B (zh) * 2018-05-11 2021-08-10 浙江华贝药业有限责任公司 2，2，2-三氟-n-[(s)-4-羰基四氢萘-1-基]-乙酰胺的纯化工艺
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US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
WO2020168197A1 (en) 2019-02-15 2020-08-20 Incyte Corporation Pyrrolo[2,3-d]pyrimidinone compounds as cdk2 inhibitors
WO2020180959A1 (en) 2019-03-05 2020-09-10 Incyte Corporation Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
US11919904B2 (en) 2019-03-29 2024-03-05 Incyte Corporation Sulfonylamide compounds as CDK2 inhibitors
WO2020223558A1 (en) 2019-05-01 2020-11-05 Incyte Corporation Tricyclic amine compounds as cdk2 inhibitors
US11440914B2 (en) 2019-05-01 2022-09-13 Incyte Corporation Tricyclic amine compounds as CDK2 inhibitors
PE20221010A1 (es) 2019-08-14 2022-06-15 Incyte Corp Compuestos de imidazolil pirimidinilamina como inhibidores de cdk2
JP2022551668A (ja) 2019-10-11 2022-12-12 インサイト・コーポレイション Ｃｄｋ２阻害剤としての二環式アミン

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GB2481022B (en) 2010-06-08 2014-10-08 Dean Bowie Anchor apparatus
GB201009731D0 (en) 2010-06-10 2010-07-21 Pulmagen Therapeutics Inflamma Kinase inhibitors
SI2788349T1 (sl) * 2011-12-09 2017-01-31 Chiesi Farmaceutici S.P.A. Inhibitorji kinaze
CA2858420A1 (en) 2011-12-09 2013-06-13 Chiesi Farmaceutici S.P.A. Derivatives of 4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl urea and their use in the treatment of, inter alia, diseases of the respiratory tract
RU2623734C9 (ru) * 2011-12-09 2017-09-18 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Ингибиторы киназы
CN105308046A (zh) 2013-06-06 2016-02-03 奇斯药制品公司 激酶抑制剂
CA2914432A1 (en) * 2013-06-06 2014-12-11 Chiesi Farmaceutici S.P.A. Kinase inhibitors

Also Published As

Publication number Publication date
RU2015151886A (ru) 2017-06-08
US20160016953A1 (en) 2016-01-21
CN105377847A (zh) 2016-03-02
RU2015151886A3 (zh) 2018-03-30
AR096532A1 (es) 2016-01-13
CA2914432A1 (en) 2014-12-11
WO2014195402A1 (en) 2014-12-11
US9181242B2 (en) 2015-11-10
EP3004097A1 (en) 2016-04-13
BR112015029970A2 (pt) 2017-07-25
US20140364412A1 (en) 2014-12-11
US9440974B2 (en) 2016-09-13
KR20160018567A (ko) 2016-02-17
EP3004097B1 (en) 2018-01-17

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