HK1219958A1 - 抗體 - Google Patents

抗體

Info

Publication number
HK1219958A1
HK1219958A1 HK16108001.2A HK16108001A HK1219958A1 HK 1219958 A1 HK1219958 A1 HK 1219958A1 HK 16108001 A HK16108001 A HK 16108001A HK 1219958 A1 HK1219958 A1 HK 1219958A1
Authority
HK
Hong Kong
Prior art keywords
pac1
antibodies
human
human pac1
pac1 antibodies
Prior art date
Application number
HK16108001.2A
Other languages
English (en)
Inventor
Cen Xu
Agnes Eva Hamburger
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of HK1219958A1 publication Critical patent/HK1219958A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HK16108001.2A 2013-03-15 2016-07-08 抗體 HK1219958A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361792678P 2013-03-15 2013-03-15
PCT/US2014/029128 WO2014144632A2 (en) 2013-03-15 2014-03-14 Human pac1 antibodies

Publications (1)

Publication Number Publication Date
HK1219958A1 true HK1219958A1 (zh) 2017-04-21

Family

ID=50439531

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16106566.3A HK1218554A1 (zh) 2013-03-15 2016-06-08 抗體
HK16108001.2A HK1219958A1 (zh) 2013-03-15 2016-07-08 抗體

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK16106566.3A HK1218554A1 (zh) 2013-03-15 2016-06-08 抗體

Country Status (24)

Country Link
US (7) US9676851B2 (zh)
EP (2) EP3683237A1 (zh)
JP (3) JP6283408B2 (zh)
KR (1) KR102215405B1 (zh)
CN (1) CN105143267B (zh)
AP (1) AP2015008732A0 (zh)
AR (1) AR095611A1 (zh)
AU (2) AU2014228924B2 (zh)
CA (1) CA2906737C (zh)
CL (1) CL2015002750A1 (zh)
CR (1) CR20150575A (zh)
EA (1) EA032830B1 (zh)
ES (1) ES2770976T3 (zh)
HK (2) HK1218554A1 (zh)
IL (2) IL241382A0 (zh)
MA (1) MA38478A1 (zh)
MX (1) MX2015013181A (zh)
PE (1) PE20151923A1 (zh)
PH (1) PH12015502126A1 (zh)
SG (1) SG11201507416WA (zh)
TN (1) TN2015000425A1 (zh)
TW (2) TWI636064B (zh)
UY (1) UY35483A (zh)
WO (1) WO2014144632A2 (zh)

Families Citing this family (15)

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JP6956631B2 (ja) 2014-09-15 2021-11-02 アムジェン インコーポレイテッド 二重特異性抗ｃｇｒｐ受容体／ｐａｃ１受容体抗原結合タンパク質及びその使用
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EA039859B1 (ru) * 2016-02-03 2022-03-21 Эмджен Рисерч (Мюник) Гмбх Биспецифические конструкты антител, связывающие egfrviii и cd3
KR102444717B1 (ko) 2016-04-15 2022-09-16 하. 룬드벡 아크티에셀스카브 인간화 항-pacap 항체 및 그의 용도
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JP7317016B2 (ja) 2017-12-19 2023-07-28 スロゼン オペレーティング， インコーポレイテッド 抗ｌｒｐ５／６抗体及び使用方法
US11773171B2 (en) 2017-12-19 2023-10-03 Surrozen Operating, Inc. WNT surrogate molecules and uses thereof
JP7339262B2 (ja) 2018-01-12 2023-09-05 アムジェン インコーポレイテッド Ｐａｃ１抗体及びその使用
SG11202009629YA (en) 2018-04-02 2020-10-29 Amgen Inc Erenumab compositions and uses thereof
MA52204A (fr) 2018-04-12 2021-02-17 Amgen Inc Procédés de préparation de compositions protéiques stables
JP2022538232A (ja) 2019-06-28 2022-09-01 アムジエン・インコーポレーテツド 抗ｃｇｒｐ受容体／抗ｐａｃ１受容体二重特異性抗原結合タンパク質
CA3227990A1 (en) * 2021-08-06 2023-02-09 Amgen Inc. Isolation of therapeutic protein
TW202330607A (zh) * 2021-09-30 2023-08-01 大陸商江蘇恆瑞醫藥股份有限公司 特異性結合ｃｇｒｐ和ｐａｃａｐ的抗原結合分子及其醫藥用途

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Also Published As

Publication number Publication date
US9676851B2 (en) 2017-06-13
EA201591791A1 (ru) 2016-03-31
CA2906737A1 (en) 2014-09-18
EP2970470B1 (en) 2019-12-04
AU2014228924A9 (en) 2016-06-16
CN105143267A (zh) 2015-12-09
CA2906737C (en) 2023-08-15
PE20151923A1 (es) 2016-01-14
US9822178B2 (en) 2017-11-21
EP3683237A1 (en) 2020-07-22
US20200172614A1 (en) 2020-06-04
AP2015008732A0 (en) 2015-09-30
MX2015013181A (es) 2015-12-11
US10472417B2 (en) 2019-11-12
US20160251432A1 (en) 2016-09-01
US10793631B2 (en) 2020-10-06
JP6283408B2 (ja) 2018-02-21
BR112015023429A2 (pt) 2017-11-28
JP2018076373A (ja) 2018-05-17
BR112015023429A8 (pt) 2018-01-23
UY35483A (es) 2014-08-29
US20170247451A1 (en) 2017-08-31
JP2019024501A (ja) 2019-02-21
IL241382A0 (en) 2015-11-30
US20180362645A1 (en) 2018-12-20
US9365653B2 (en) 2016-06-14
US10294298B2 (en) 2019-05-21
US20180094055A1 (en) 2018-04-05
US20160039939A1 (en) 2016-02-11
SG11201507416WA (en) 2015-10-29
AU2014228924B2 (en) 2019-04-18
JP6443870B2 (ja) 2018-12-26
TN2015000425A1 (en) 2017-01-03
KR20150128982A (ko) 2015-11-18
US20150010560A1 (en) 2015-01-08
EP2970470A2 (en) 2016-01-20
AU2019204980A1 (en) 2019-08-01
CN105143267B (zh) 2020-06-26
KR102215405B1 (ko) 2021-02-10
US10053507B2 (en) 2018-08-21
IL262804A (en) 2018-12-31
WO2014144632A3 (en) 2014-11-20
PH12015502126A1 (en) 2016-01-25
WO2014144632A8 (en) 2015-12-30
HK1218554A1 (zh) 2017-02-24
TW201902931A (zh) 2019-01-16
WO2014144632A2 (en) 2014-09-18
CR20150575A (es) 2016-01-06
ES2770976T3 (es) 2020-07-06
JP2016514458A (ja) 2016-05-23
EA032830B1 (ru) 2019-07-31
AU2014228924A1 (en) 2015-10-01
AR095611A1 (es) 2015-10-28
CL2015002750A1 (es) 2016-03-04
TWI636064B (zh) 2018-09-21
MA38478A1 (fr) 2017-11-30
TW201522375A (zh) 2015-06-16

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