CR20150575A - Anticuerpos humanos pac1 - Google Patents

Anticuerpos humanos pac1

Info

Publication number
CR20150575A
CR20150575A CR20150575A CR20150575A CR20150575A CR 20150575 A CR20150575 A CR 20150575A CR 20150575 A CR20150575 A CR 20150575A CR 20150575 A CR20150575 A CR 20150575A CR 20150575 A CR20150575 A CR 20150575A
Authority
CR
Costa Rica
Prior art keywords
pac1
human antibodies
antibodies
binding fragments
antigen
Prior art date
Application number
CR20150575A
Other languages
English (en)
Inventor
Cen Xu
Agnes Eva Hamburger
Original Assignee
Xdx Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xdx Technology Llc filed Critical Xdx Technology Llc
Publication of CR20150575A publication Critical patent/CR20150575A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Se proporcionan anticuerpos y fragmentos de unión a antígeno de los mismos que se unen a PAC1 humano. También se proporcionan ácidos nucleicos que codifican los anticuerpos y fragmentos de unión a antígeno de los mismos, vectores y células que codifican la misma.
CR20150575A 2013-03-15 2015-10-15 Anticuerpos humanos pac1 CR20150575A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361792678P 2013-03-15 2013-03-15
PCT/US2014/029128 WO2014144632A2 (en) 2013-03-15 2014-03-14 Human pac1 antibodies

Publications (1)

Publication Number Publication Date
CR20150575A true CR20150575A (es) 2016-01-06

Family

ID=50439531

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20150575A CR20150575A (es) 2013-03-15 2015-10-15 Anticuerpos humanos pac1

Country Status (24)

Country Link
US (7) US9676851B2 (es)
EP (2) EP2970470B1 (es)
JP (3) JP6283408B2 (es)
KR (1) KR102215405B1 (es)
CN (1) CN105143267B (es)
AP (1) AP2015008732A0 (es)
AR (1) AR095611A1 (es)
AU (2) AU2014228924B2 (es)
CA (1) CA2906737C (es)
CL (1) CL2015002750A1 (es)
CR (1) CR20150575A (es)
EA (1) EA032830B1 (es)
ES (1) ES2770976T3 (es)
HK (2) HK1218554A1 (es)
IL (2) IL241382A0 (es)
MA (1) MA38478A1 (es)
MX (1) MX2015013181A (es)
PE (1) PE20151923A1 (es)
PH (1) PH12015502126A1 (es)
SG (1) SG11201507416WA (es)
TN (1) TN2015000425A1 (es)
TW (2) TWI636064B (es)
UY (1) UY35483A (es)
WO (1) WO2014144632A2 (es)

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EA039859B1 (ru) * 2016-02-03 2022-03-21 Эмджен Рисерч (Мюник) Гмбх Биспецифические конструкты антител, связывающие egfrviii и cd3
EP3426686A4 (en) 2016-04-15 2019-11-06 Alder Biopharmaceuticals, Inc. HUMANIZED ANTI-PACAP ANTIBODIES AND USES THEREOF
AR113022A1 (es) * 2017-09-29 2020-01-15 Lilly Co Eli Anticuerpo anti-pacap
AU2018346151A1 (en) * 2017-10-04 2020-04-02 Amgen Inc. Transthyretin immunoglobulin fusions
CA3085785A1 (en) * 2017-12-19 2019-06-27 Surrozen, Inc. Anti-lrp5/6 antibodies and methods of use
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CN111566126A (zh) 2018-01-12 2020-08-21 美国安进公司 Pac1抗体及其用途
KR20200139720A (ko) 2018-04-02 2020-12-14 암젠 인크 에레누맙 조성물 및 이의 용도
WO2019199476A1 (en) 2018-04-12 2019-10-17 Amgen Inc. Methods for making stable protein compositions
JP2022538232A (ja) 2019-06-28 2022-09-01 アムジエン・インコーポレーテツド 抗ｃｇｒｐ受容体／抗ｐａｃ１受容体二重特異性抗原結合タンパク質
CA3227990A1 (en) * 2021-08-06 2023-02-09 Amgen Inc. Isolation of therapeutic protein
WO2023051786A1 (zh) * 2021-09-30 2023-04-06 江苏恒瑞医药股份有限公司 特异性结合cgrp和pacap的抗原结合分子及其医药用途

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Also Published As

Publication number Publication date
AU2019204980A1 (en) 2019-08-01
US10053507B2 (en) 2018-08-21
BR112015023429A8 (pt) 2018-01-23
KR102215405B1 (ko) 2021-02-10
IL241382A0 (en) 2015-11-30
WO2014144632A8 (en) 2015-12-30
EA032830B1 (ru) 2019-07-31
WO2014144632A2 (en) 2014-09-18
TWI636064B (zh) 2018-09-21
WO2014144632A3 (en) 2014-11-20
CA2906737A1 (en) 2014-09-18
US20170247451A1 (en) 2017-08-31
US20200172614A1 (en) 2020-06-04
US9676851B2 (en) 2017-06-13
BR112015023429A2 (pt) 2017-11-28
JP6283408B2 (ja) 2018-02-21
US10793631B2 (en) 2020-10-06
US20150010560A1 (en) 2015-01-08
ES2770976T3 (es) 2020-07-06
CA2906737C (en) 2023-08-15
EA201591791A1 (ru) 2016-03-31
PH12015502126A1 (en) 2016-01-25
US10472417B2 (en) 2019-11-12
SG11201507416WA (en) 2015-10-29
HK1218554A1 (zh) 2017-02-24
AU2014228924A1 (en) 2015-10-01
EP2970470B1 (en) 2019-12-04
TW201902931A (zh) 2019-01-16
US20160039939A1 (en) 2016-02-11
EP2970470A2 (en) 2016-01-20
AP2015008732A0 (en) 2015-09-30
US9365653B2 (en) 2016-06-14
PE20151923A1 (es) 2016-01-14
EP3683237A1 (en) 2020-07-22
JP2018076373A (ja) 2018-05-17
MX2015013181A (es) 2015-12-11
JP6443870B2 (ja) 2018-12-26
CN105143267B (zh) 2020-06-26
AR095611A1 (es) 2015-10-28
US9822178B2 (en) 2017-11-21
US20180362645A1 (en) 2018-12-20
US10294298B2 (en) 2019-05-21
MA38478A1 (fr) 2017-11-30
HK1219958A1 (zh) 2017-04-21
TW201522375A (zh) 2015-06-16
CL2015002750A1 (es) 2016-03-04
US20160251432A1 (en) 2016-09-01
JP2016514458A (ja) 2016-05-23
AU2014228924B2 (en) 2019-04-18
CN105143267A (zh) 2015-12-09
US20180094055A1 (en) 2018-04-05
UY35483A (es) 2014-08-29
AU2014228924A9 (en) 2016-06-16
TN2015000425A1 (en) 2017-01-03
IL262804A (en) 2018-12-31
KR20150128982A (ko) 2015-11-18
JP2019024501A (ja) 2019-02-21

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