HK1179956A1 - 作為 調節劑的稠合雜環衍生物 - Google Patents

作為 調節劑的稠合雜環衍生物

Info

Publication number
HK1179956A1
HK1179956A1 HK13107150.6A HK13107150A HK1179956A1 HK 1179956 A1 HK1179956 A1 HK 1179956A1 HK 13107150 A HK13107150 A HK 13107150A HK 1179956 A1 HK1179956 A1 HK 1179956A1
Authority
HK
Hong Kong
Prior art keywords
heterocycic
modulators
fused
derivatives
heterocycic derivatives
Prior art date
Application number
HK13107150.6A
Other languages
English (en)
Inventor
．施密德
．伊韋瑪巴克
．庫倫
．斯列德裡格特
．范東恩
．登哈爾托赫
．霍布森
Original Assignee
艾伯維私營有限責任公司
艾伯維股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44358260&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1179956(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 艾伯維私營有限責任公司, 艾伯維股份有限公司 filed Critical 艾伯維私營有限責任公司
Publication of HK1179956A1 publication Critical patent/HK1179956A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK13107150.6A 2010-07-09 2013-06-19 作為 調節劑的稠合雜環衍生物 HK1179956A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36278410P 2010-07-09 2010-07-09
EP10169107 2010-07-09
US201161446541P 2011-02-25 2011-02-25
EP11156007 2011-02-25
PCT/EP2011/061586 WO2012004373A1 (en) 2010-07-09 2011-07-08 Fused heterocyclic derivatives as s1p modulators

Publications (1)

Publication Number Publication Date
HK1179956A1 true HK1179956A1 (zh) 2013-10-11

Family

ID=44358260

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13107150.6A HK1179956A1 (zh) 2010-07-09 2013-06-19 作為 調節劑的稠合雜環衍生物

Country Status (27)

Country Link
US (3) US8796262B2 (zh)
EP (1) EP2590980B1 (zh)
JP (1) JP5973429B2 (zh)
KR (1) KR101889694B1 (zh)
CN (1) CN103068827B (zh)
AR (1) AR082136A1 (zh)
AU (1) AU2011275755B2 (zh)
BR (1) BR112013000627B1 (zh)
CA (1) CA2804137C (zh)
CL (1) CL2013000069A1 (zh)
CO (1) CO6670577A2 (zh)
CR (1) CR20130056A (zh)
DO (1) DOP2013000009A (zh)
EC (1) ECSP13012416A (zh)
ES (1) ES2653682T3 (zh)
HK (1) HK1179956A1 (zh)
IL (1) IL224054A (zh)
MX (1) MX2013000360A (zh)
MY (1) MY161229A (zh)
NZ (1) NZ605491A (zh)
PE (1) PE20130592A1 (zh)
RU (1) RU2576660C2 (zh)
SG (1) SG186952A1 (zh)
TW (1) TWI522361B (zh)
UY (1) UY33496A (zh)
WO (1) WO2012004373A1 (zh)
ZA (1) ZA201300157B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE48301E1 (en) 2010-07-09 2020-11-10 Abbvie B.V. Fused heterocyclic derivatives as S1P modulators
TW201643169A (zh) 2010-07-09 2016-12-16 艾伯維股份有限公司 作為s1p調節劑的螺-哌啶衍生物
JP2016011257A (ja) * 2012-10-23 2016-01-21 大日本住友製薬株式会社 テトラヒドロオキサゾロピリジン誘導体
EP3341369A1 (en) * 2015-08-28 2018-07-04 AbbVie Inc. Fused heterocyclic compounds as s1p modulators
EP3535244A1 (en) 2016-11-02 2019-09-11 Abbvie Deutschland GmbH & Co. KG Spiro-compounds as s1p modulators
BR112022008137A2 (pt) * 2019-10-31 2022-07-19 Escape Bio Inc Processos para preparar um modulador de receptor s1p
CA3159378A1 (en) * 2019-10-31 2021-05-06 ESCAPE Bio, Inc. Solid forms of an s1p-receptor modulator
JP7307282B2 (ja) * 2020-03-04 2023-07-11 ヒーリオイースト ファーマシューティカル カンパニー リミテッド ベンゾ２－アザスピロ［４．４］ノナン系化合物及びその使用

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Also Published As

Publication number Publication date
US20140066433A1 (en) 2014-03-06
AU2011275755A8 (en) 2013-02-14
NZ605491A (en) 2014-08-29
KR20140005849A (ko) 2014-01-15
TWI522361B (zh) 2016-02-21
RU2576660C2 (ru) 2016-03-10
JP5973429B2 (ja) 2016-08-23
ES2653682T3 (es) 2018-02-08
KR101889694B1 (ko) 2018-08-21
SG186952A1 (en) 2013-02-28
AU2011275755B2 (en) 2015-04-09
CR20130056A (es) 2013-06-12
IL224054A (en) 2016-07-31
CA2804137C (en) 2019-06-11
AU2011275755A1 (en) 2013-01-31
JP2013531002A (ja) 2013-08-01
ZA201300157B (en) 2017-05-31
US9096612B2 (en) 2015-08-04
RU2013105444A (ru) 2014-08-20
CN103068827B (zh) 2016-05-04
CN103068827A (zh) 2013-04-24
BR112013000627A2 (pt) 2016-05-24
BR112013000627B1 (pt) 2020-12-08
US20150284403A1 (en) 2015-10-08
DOP2013000009A (es) 2013-10-15
ECSP13012416A (es) 2013-03-28
CL2013000069A1 (es) 2013-06-07
CA2804137A1 (en) 2012-01-12
US20130203737A1 (en) 2013-08-08
US8796262B2 (en) 2014-08-05
TW201206945A (en) 2012-02-16
EP2590980B1 (en) 2017-09-20
WO2012004373A1 (en) 2012-01-12
UY33496A (es) 2012-01-31
CO6670577A2 (es) 2013-05-15
MY161229A (en) 2017-04-14
AR082136A1 (es) 2012-11-14
EP2590980A1 (en) 2013-05-15
US9670220B2 (en) 2017-06-06
MX2013000360A (es) 2013-06-28
PE20130592A1 (es) 2013-05-22

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