HK1163505A1 - Arranging interaction and back pressure chambers for microfluidization - Google Patents
Arranging interaction and back pressure chambers for microfluidizationInfo
- Publication number
- HK1163505A1 HK1163505A1 HK12103981.1A HK12103981A HK1163505A1 HK 1163505 A1 HK1163505 A1 HK 1163505A1 HK 12103981 A HK12103981 A HK 12103981A HK 1163505 A1 HK1163505 A1 HK 1163505A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- microfluidization
- back pressure
- pressure chambers
- arranging
- interaction
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/432—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
- B01F25/4323—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa using elements provided with a plurality of channels or using a plurality of tubes which can either be placed between common spaces or collectors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/50—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
- B01F25/52—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle with a rotary stirrer in the recirculation tube
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/27—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices
- B01F27/271—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator
- B01F27/2711—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator provided with intermeshing elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
- B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/82—Combinations of dissimilar mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/82—Combinations of dissimilar mixers
- B01F33/821—Combinations of dissimilar mixers with consecutive receptacles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/82—Combinations of dissimilar mixers
- B01F33/821—Combinations of dissimilar mixers with consecutive receptacles
- B01F33/8212—Combinations of dissimilar mixers with consecutive receptacles with moving and non-moving stirring devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0413—Numerical information
- B01F2215/0418—Geometrical information
- B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0413—Numerical information
- B01F2215/0436—Operational information
- B01F2215/045—Numerical flow-rate values
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0413—Numerical information
- B01F2215/0436—Operational information
- B01F2215/0468—Numerical pressure values
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0413—Numerical information
- B01F2215/0436—Operational information
- B01F2215/0472—Numerical temperature values
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0413—Numerical information
- B01F2215/0436—Operational information
- B01F2215/0477—Numerical time values
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0413—Numerical information
- B01F2215/0436—Operational information
- B01F2215/0481—Numerical speed values
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28354809P | 2009-12-03 | 2009-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1163505A1 true HK1163505A1 (en) | 2012-09-14 |
Family
ID=43927822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12103981.1A HK1163505A1 (en) | 2009-12-03 | 2012-04-23 | Arranging interaction and back pressure chambers for microfluidization |
Country Status (24)
Country | Link |
---|---|
US (1) | US20130189311A1 (pt) |
EP (2) | EP2380558B2 (pt) |
JP (2) | JP5751678B2 (pt) |
KR (2) | KR101643918B1 (pt) |
CN (2) | CN102740832B (pt) |
AU (1) | AU2010325751B2 (pt) |
BR (1) | BR112012013426B8 (pt) |
CA (1) | CA2782650C (pt) |
CL (1) | CL2012001398A1 (pt) |
DK (1) | DK2380558T4 (pt) |
EA (1) | EA031593B1 (pt) |
ES (2) | ES2393182T5 (pt) |
HK (1) | HK1163505A1 (pt) |
HR (1) | HRP20120965T1 (pt) |
IL (1) | IL220082B (pt) |
MX (1) | MX340263B (pt) |
NZ (1) | NZ600254A (pt) |
PL (1) | PL2380558T5 (pt) |
PT (1) | PT2380558E (pt) |
RS (1) | RS52565B (pt) |
SG (1) | SG10201501613SA (pt) |
SI (2) | SI2380558T2 (pt) |
SM (1) | SMT201300026B (pt) |
WO (1) | WO2011067672A2 (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007054233B4 (de) * | 2007-11-12 | 2010-06-10 | Ika-Werke Gmbh & Co. Kg | Vorrichtung zum Dispergieren oder Homogenisieren |
DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
EP2356983B1 (en) | 2009-12-03 | 2013-02-20 | Novartis AG | Circulation of components during homogenization of emulsions |
SI2380558T2 (sl) * | 2009-12-03 | 2019-11-29 | Novartis Ag | Izdelava emulzije z razmestitvijo interakcijske in protitlačne komore za mikrofluidizacijo |
CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
NZ599881A (en) | 2009-12-03 | 2014-01-31 | Novartis Ag | Hydrophilic filtration during manufacture of vaccine adjuvants |
FR2981581B1 (fr) * | 2011-10-20 | 2013-11-29 | Jean-Claude Epiphani | Procede de fabrication d'une emulsion aqueuse d'une substance active huileuse pour application cosmetique, alimentaire ou pharmaceutique |
RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
RU2015106930A (ru) | 2012-09-06 | 2016-10-20 | Новартис Аг | Комбинированные вакцины с менингококком серогруппы в и к/д/с |
BR112015008040A2 (pt) | 2012-10-12 | 2017-07-04 | Glaxosmithkline Biologicals Sa | composição de vacina, vacina de combinação, e, processos para preparar um componente ap e para a fabricação de uma composição de vacina |
EP2934574A1 (en) | 2012-12-18 | 2015-10-28 | GlaxoSmithKline Biologicals SA | Conjugates for protecting against diphtheria and/or tetanus |
US11000046B2 (en) | 2012-12-27 | 2021-05-11 | Jean-Claude | Method for manufacturing an oil-in-water emulsion from an oily active substance, for cosmetic, food, or pharmaceutical use |
CN106659997A (zh) * | 2014-05-30 | 2017-05-10 | 微射流国际公司 | 气蚀减少的互作用腔 |
AU2015323334B2 (en) | 2014-09-26 | 2021-02-25 | Seqirus UK Limited | Vaccination of immunocompromised subjects |
DK3197487T3 (da) | 2014-09-26 | 2022-09-05 | Seqirus Uk Ltd | Vaccination af immunsvækkede individer |
ES2721306T3 (es) | 2014-12-02 | 2019-07-30 | Novartis Ag | Fabricación de composiciones que contienen tensioactivo |
KR102079141B1 (ko) * | 2016-05-11 | 2020-02-19 | 주식회사 엘지화학 | 고압 균질화 장치 및 이를 이용한 그래핀의 제조방법 |
JP2019163345A (ja) * | 2016-08-02 | 2019-09-26 | 京都プラント工業株式会社 | バイオ燃料の製造方法 |
CN109790504A (zh) * | 2016-09-29 | 2019-05-21 | 高雄医学大学 | 一种从组织分离细胞的装置 |
DE102018205493A1 (de) * | 2018-04-11 | 2019-10-17 | B. Braun Melsungen Ag | Verfahren zur Herstellung einer O/W-Emulsion, O/W-Emulsion und Anlage zur Herstellung einer O/W-Emulsion |
EP4309773A1 (en) * | 2022-06-08 | 2024-01-24 | Contemporary Amperex Technology Co., Limited | Mixed dispersion device |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4060082A (en) | 1976-08-16 | 1977-11-29 | Mpl, Inc. | Dual-ingredient medication dispenser |
US4340482A (en) | 1978-02-21 | 1982-07-20 | Millipore Corporation | Process for grafting amino acid molecules onto preformed polymer surfaces and products prepared thereby |
US4673504A (en) | 1980-10-27 | 1987-06-16 | Cuno Inc. | Charge modified microporous membrane |
US4473474A (en) | 1980-10-27 | 1984-09-25 | Amf Inc. | Charge modified microporous membrane, process for charge modifying said membrane and process for filtration of fluid |
US4432875A (en) | 1981-05-29 | 1984-02-21 | Brunswick Corporation | Semi-permeable membranes and processes for making the same |
US4473475A (en) | 1981-05-29 | 1984-09-25 | Amf Inc. | Charge modified microporous membrane, process for charge modifying said membrane, and process for filtration of fluids |
US4413074A (en) | 1982-01-25 | 1983-11-01 | Brunswick Corporation | Hydrophilic surfaces and process for making the same |
NZ209308A (en) | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
US4705753A (en) | 1984-06-08 | 1987-11-10 | Gregor Harry P | Biologically active acrylonitrile-based copolymeric membrane |
US4618533A (en) | 1984-11-30 | 1986-10-21 | Millipore Corporation | Porous membrane having hydrophilic surface and process |
US4794002A (en) | 1985-11-01 | 1988-12-27 | Monsanto Company | Modified polymeric surfaces and process for preparing same |
US4964990A (en) | 1987-05-20 | 1990-10-23 | Gelman Sciences, Inc. | Filtration membranes and method of making the same |
US4943374A (en) | 1988-04-21 | 1990-07-24 | Gessner & Co., Gmbh | Use of a microporous membrane constructed of polyether sulfon and hydrophilization agent for the filtration of beer |
AU4529289A (en) | 1988-10-17 | 1990-05-14 | Sepracor, Inc. | Process for the covalent surface modification of hydrophobic polymers and articles made therefrom |
CA2017507C (en) * | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
JPH0614756Y2 (ja) | 1991-06-26 | 1994-04-20 | 株式会社アルテ | 組み立て式の2室式容器兼用注射器 |
US5178765A (en) | 1991-09-18 | 1993-01-12 | Gelman Sciences Inc. | Hydrophilic membranes prepared from polyethersulfone/poly-2-oxazoline/polyvinylpyrrolidone blend |
US5277812A (en) | 1993-02-12 | 1994-01-11 | Gelman Sciences Inc. | Inter-penetrating network charge modified microporous membrane |
US5531893A (en) | 1993-02-12 | 1996-07-02 | Gelman Sciences Inc. | Inter-penetrating network charge modified microporous membrane |
US5843334A (en) † | 1994-06-20 | 1998-12-01 | Nippon Shinyaku Co., Ltd. | Method of producing emulsions and an emulsification apparatus |
US5496284A (en) | 1994-09-27 | 1996-03-05 | Waldenburg; Ottfried | Dual-chamber syringe & method |
DE19612966B4 (de) | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
AU3186297A (en) | 1996-07-05 | 1998-02-02 | Debiotech S.A. | Dual-chamber syringe for mixing two substances prior to injection |
CA2271846A1 (en) | 1996-11-12 | 1998-05-22 | Dean T. Tsou | Hydrophilic polymeric phase inversion membrane |
US5971953A (en) | 1998-01-09 | 1999-10-26 | Bachynsky; Nicholas | Dual chamber syringe apparatus |
WO1999017820A1 (en) | 1997-10-03 | 1999-04-15 | Texas Pharmaceuticals, Inc. | Improved dual chamber syringe apparatus |
US6039872A (en) | 1997-10-27 | 2000-03-21 | Pall Corporation | Hydrophilic membrane |
JP4117106B2 (ja) | 1998-03-30 | 2008-07-16 | 株式会社荏原製作所 | マンガン含有水の処理方法及び装置 |
GB9808689D0 (en) | 1998-04-23 | 1998-06-24 | Kalsep Ltd | Improved membrane |
ES2204503T3 (es) * | 1999-02-03 | 2004-05-01 | Forbes Medi-Tech Inc. | Metodo para preparar microparticulas de fitosteroles o fitostanoles. |
US6193077B1 (en) | 1999-02-08 | 2001-02-27 | Osmonics, Inc. | Non-cracking hydrophilic polyethersulfone membranes |
US6555139B2 (en) * | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
GB9923176D0 (en) | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
MY134424A (en) | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
WO2004087204A2 (en) * | 2003-04-04 | 2004-10-14 | Pfizer Products Inc. | Microfluidized oil-in-water emulsions and vaccine compositions |
CA2528095C (en) † | 2003-06-04 | 2014-10-14 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof |
US20050208083A1 (en) * | 2003-06-04 | 2005-09-22 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof |
GB0319500D0 (en) * | 2003-08-19 | 2003-09-17 | Resolution Chemicals Ltd | Particle-size reduction apparatus,and use thereof |
US20080234632A1 (en) | 2004-03-23 | 2008-09-25 | Mitsuru Hasegawa | Pre-Filled Syringe |
WO2006044463A1 (en) | 2004-10-13 | 2006-04-27 | 3M Innovative Properties Company | Method for preparing hydrophilic polyethersulfone membrane |
CA2578176C (en) † | 2004-11-09 | 2013-09-24 | Novagali Pharma Sa | Ophthalmic emulsions containing an immunosuppressive agent |
JP5869744B2 (ja) * | 2005-03-23 | 2016-02-24 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Cd4t細胞および/または改善された記憶b細胞応答を誘導するためのインフルエンザウイルスおよび水中油型エマルジョンアジュバントの使用 |
US8703095B2 (en) | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
WO2008051186A2 (en) * | 2005-08-09 | 2008-05-02 | Nanobio Corporation | Nanoemulsion containing compositions having ant i -inflammatory activity |
WO2007052155A2 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
FR2896162B1 (fr) | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
NZ577405A (en) * | 2006-12-06 | 2012-08-31 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
US8187554B2 (en) * | 2008-04-23 | 2012-05-29 | Microfluidics International Corporation | Apparatus and methods for nanoparticle generation and process intensification of transport and reaction systems |
SI2380558T2 (sl) * | 2009-12-03 | 2019-11-29 | Novartis Ag | Izdelava emulzije z razmestitvijo interakcijske in protitlačne komore za mikrofluidizacijo |
NZ599881A (en) † | 2009-12-03 | 2014-01-31 | Novartis Ag | Hydrophilic filtration during manufacture of vaccine adjuvants |
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