HK1154904A1 - 天然 抗體及其抑制劑 - Google Patents
天然 抗體及其抑制劑Info
- Publication number
- HK1154904A1 HK1154904A1 HK11109256.7A HK11109256A HK1154904A1 HK 1154904 A1 HK1154904 A1 HK 1154904A1 HK 11109256 A HK11109256 A HK 11109256A HK 1154904 A1 HK1154904 A1 HK 1154904A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- igm
- inhibitors
- natural
- antibodies
- natural igm
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54912304P | 2004-03-01 | 2004-03-01 | |
US58864804P | 2004-07-16 | 2004-07-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1154904A1 true HK1154904A1 (zh) | 2012-05-04 |
Family
ID=34922704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11109256.7A HK1154904A1 (zh) | 2004-03-01 | 2011-09-01 | 天然 抗體及其抑制劑 |
Country Status (10)
Country | Link |
---|---|
US (5) | US7442783B2 (zh) |
EP (2) | EP1725659B1 (zh) |
JP (3) | JP5557982B2 (zh) |
AT (1) | ATE498010T1 (zh) |
AU (1) | AU2005219839B9 (zh) |
CA (1) | CA2560066A1 (zh) |
DE (1) | DE602005026260D1 (zh) |
HK (1) | HK1154904A1 (zh) |
IL (1) | IL177825A (zh) |
WO (1) | WO2005085288A2 (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2560066A1 (en) * | 2004-03-01 | 2005-09-15 | The Cbr Institute For Biomedical Research, Inc. | Natural igm antibodies and inhibitors thereof |
US20100136684A1 (en) * | 2004-03-01 | 2010-06-03 | Carroll Michael C | Natural IgM Antibodies |
EP2510000B1 (en) * | 2009-12-07 | 2017-07-19 | Decimmune Therapeutics Inc. | Anti-inflammatory antibodies and uses therefor |
MX2012013875A (es) * | 2010-06-03 | 2013-04-17 | Abraxis Bioscience Llc | Anticuerpos de union sparc en sangre periferica y usos de los mismos. |
WO2014055392A2 (en) * | 2012-10-01 | 2014-04-10 | Decimmune Therapeutics, Inc. | Method of protecting cardiac function |
CA2905940A1 (en) | 2013-03-12 | 2014-10-09 | Decimmune Therapeutics, Inc. | Humanized, anti-n2 antibodies |
JP6551825B2 (ja) * | 2014-02-10 | 2019-07-31 | 公立大学法人首都大学東京 | クロマチン構造制御剤 |
Family Cites Families (60)
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
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JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
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US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
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ATE151110T1 (de) | 1988-09-02 | 1997-04-15 | Protein Eng Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
BR8907069A (pt) | 1988-09-06 | 1991-01-02 | Asarco Inc | Dispositivo queimador e metodo para fundir cobre |
US5750373A (en) | 1990-12-03 | 1998-05-12 | Genentech, Inc. | Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5096815A (en) | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
WO1991000906A1 (en) | 1989-07-12 | 1991-01-24 | Genetics Institute, Inc. | Chimeric and transgenic animals capable of producing human antibodies |
WO1991007087A1 (en) | 1989-11-13 | 1991-05-30 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
AU7163091A (en) * | 1989-12-12 | 1991-07-18 | Biomedical Research Institute | Novel malarial sporozoite peptide antigens |
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US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
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US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
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US6174530B1 (en) | 1993-05-05 | 2001-01-16 | Gryphon Sciences | Homogeneous polyoxime compositions and their preparation by parallel assembly |
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US20100136684A1 (en) | 2004-03-01 | 2010-06-03 | Carroll Michael C | Natural IgM Antibodies |
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-
2005
- 2005-03-01 CA CA002560066A patent/CA2560066A1/en not_active Abandoned
- 2005-03-01 EP EP05723931A patent/EP1725659B1/en not_active Not-in-force
- 2005-03-01 AU AU2005219839A patent/AU2005219839B9/en not_active Ceased
- 2005-03-01 JP JP2007501869A patent/JP5557982B2/ja not_active Expired - Fee Related
- 2005-03-01 WO PCT/US2005/006276 patent/WO2005085288A2/en active Application Filing
- 2005-03-01 DE DE602005026260T patent/DE602005026260D1/de active Active
- 2005-03-01 AT AT05723931T patent/ATE498010T1/de not_active IP Right Cessation
- 2005-03-01 EP EP10185693.8A patent/EP2290077B1/en not_active Not-in-force
- 2005-03-01 US US11/069,834 patent/US7442783B2/en active Active
-
2006
- 2006-08-31 IL IL177825A patent/IL177825A/en not_active IP Right Cessation
-
2008
- 2008-10-28 US US12/259,767 patent/US20090176966A1/en not_active Abandoned
-
2011
- 2011-02-01 JP JP2011019668A patent/JP5618852B2/ja not_active Expired - Fee Related
- 2011-09-01 HK HK11109256.7A patent/HK1154904A1/zh not_active IP Right Cessation
-
2013
- 2013-04-09 US US13/859,054 patent/US9657060B2/en active Active
-
2014
- 2014-04-24 JP JP2014089965A patent/JP2014155497A/ja active Pending
-
2015
- 2015-07-23 US US14/806,924 patent/US9914751B2/en active Active
-
2017
- 2017-05-08 US US15/588,933 patent/US20170342109A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2005219839A1 (en) | 2005-09-15 |
JP2011139704A (ja) | 2011-07-21 |
US7442783B2 (en) | 2008-10-28 |
US20090176966A1 (en) | 2009-07-09 |
WO2005085288A2 (en) | 2005-09-15 |
JP2014155497A (ja) | 2014-08-28 |
EP2290077B1 (en) | 2016-01-27 |
IL177825A0 (en) | 2006-12-31 |
US20140127214A1 (en) | 2014-05-08 |
JP5618852B2 (ja) | 2014-11-05 |
US20050276811A1 (en) | 2005-12-15 |
JP5557982B2 (ja) | 2014-07-23 |
AU2005219839B9 (en) | 2011-12-22 |
JP2008504807A (ja) | 2008-02-21 |
US20170342109A1 (en) | 2017-11-30 |
US9657060B2 (en) | 2017-05-23 |
EP2290077A2 (en) | 2011-03-02 |
CA2560066A1 (en) | 2005-09-15 |
DE602005026260D1 (de) | 2011-03-24 |
WO2005085288A3 (en) | 2006-08-03 |
AU2005219839B2 (en) | 2011-11-24 |
US20160280740A1 (en) | 2016-09-29 |
IL177825A (en) | 2013-02-28 |
EP1725659A2 (en) | 2006-11-29 |
ATE498010T1 (de) | 2011-02-15 |
EP2290077A3 (en) | 2011-05-18 |
US9914751B2 (en) | 2018-03-13 |
EP1725659B1 (en) | 2011-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20200301 |