CY1113224T1 - Νεο αντισωμα αντι-ρlgf - Google Patents
Νεο αντισωμα αντι-ρlgfInfo
- Publication number
- CY1113224T1 CY1113224T1 CY20121100535T CY121100535T CY1113224T1 CY 1113224 T1 CY1113224 T1 CY 1113224T1 CY 20121100535 T CY20121100535 T CY 20121100535T CY 121100535 T CY121100535 T CY 121100535T CY 1113224 T1 CY1113224 T1 CY 1113224T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pllgf
- antibody
- new anti
- fragments
- pigf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Η παρούσα εφεύρεση παρέχει νέα μονοκλωνικά αντισώματα που στοχεύουν στον ΡΙGF και σε θραύσματα και παράγωγα αυτών, πιο συγκεκριμένα σε ανθρωποποιημένα αντισώματα και θραύσματα αυτών για χρήση στη θεραπεία και / ή στην πρόληψη της παθολογικής αγγειογένεσης.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66476805P | 2005-03-24 | 2005-03-24 | |
EP06721544A EP1869085B1 (en) | 2005-03-24 | 2006-03-24 | Novel anti-plgf antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113224T1 true CY1113224T1 (el) | 2016-04-13 |
Family
ID=36928446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100535T CY1113224T1 (el) | 2005-03-24 | 2012-06-12 | Νεο αντισωμα αντι-ρlgf |
Country Status (27)
Country | Link |
---|---|
US (3) | US7875704B2 (el) |
EP (2) | EP2447281B1 (el) |
JP (2) | JP5164829B2 (el) |
KR (1) | KR101314014B1 (el) |
CN (1) | CN101184776B (el) |
AT (1) | ATE549358T1 (el) |
AU (2) | AU2006227571B8 (el) |
BR (1) | BRPI0609151B8 (el) |
CA (1) | CA2601267C (el) |
CY (1) | CY1113224T1 (el) |
DK (1) | DK1869085T3 (el) |
EA (1) | EA013970B1 (el) |
ES (2) | ES2565481T3 (el) |
HK (1) | HK1116803A1 (el) |
HR (1) | HRP20120477T1 (el) |
IL (1) | IL185754A (el) |
ME (1) | ME01446B (el) |
MX (1) | MX2007011735A (el) |
NO (1) | NO341877B1 (el) |
NZ (1) | NZ561763A (el) |
PL (1) | PL1869085T3 (el) |
PT (1) | PT1869085E (el) |
RS (1) | RS52372B (el) |
SI (1) | SI1869085T1 (el) |
UA (1) | UA94707C2 (el) |
WO (1) | WO2006099698A2 (el) |
ZA (1) | ZA200707258B (el) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085796A2 (en) * | 2000-05-12 | 2001-11-15 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Use of inhibitors of placental growth factor for the treatment of pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage |
CA2601267C (en) | 2005-03-24 | 2014-02-18 | Thromb-X N.V. | Novel anti-plgf antibody |
CN101534865A (zh) * | 2005-10-19 | 2009-09-16 | Ibc药品公司 | 生物活性装配体的制备方法及其用途 |
US9029508B2 (en) * | 2008-04-29 | 2015-05-12 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
PE20100092A1 (es) | 2008-06-03 | 2010-03-12 | Abbott Lab | Inmunoglobulina con dominio variable dual y usos de la misma |
PE20100054A1 (es) | 2008-06-03 | 2010-03-03 | Abbott Lab | Inmunoglobulina con dominio variable dual |
RU2011104348A (ru) | 2008-07-08 | 2012-08-20 | Эбботт Лэборетриз (Us) | Иммуноглобулины с двойным вариабельным доменом против простагландина е2 и их применение |
CA2736929C (en) | 2008-10-02 | 2019-02-26 | Life Sciences Research Partners Vzw | Inhibition of plgf to treat philadelphia chromosome positive leukemia |
SG172355A1 (en) * | 2008-12-23 | 2011-07-28 | Genentech Inc | Methods and compositions for diagnostic use in cancer patients |
MX2011011670A (es) * | 2009-05-01 | 2011-11-18 | Abbott Lab | Inmunoglobulinas de dominio variable dual y usos de las mismas. |
NZ598929A (en) | 2009-09-01 | 2014-05-30 | Abbvie Inc | Dual variable domain immunoglobulins and uses thereof |
AR078651A1 (es) * | 2009-10-15 | 2011-11-23 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
JP5814951B2 (ja) | 2010-03-10 | 2015-11-17 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 免疫グロブリン溶液を精製するための方法 |
RU2582964C2 (ru) * | 2010-07-19 | 2016-04-27 | Ф.Хоффманн-Ля Рош Аг | Биомаркеры в плазме крови, предназначенные для комбинированных терапий с использованием бевацизумаба при лечении рака поджелудочной железы |
MY160445A (en) | 2010-08-03 | 2017-03-15 | Abbvie Inc | Dual Variable Domain Immunoglobulins And Uses Thereof |
JP2013539364A (ja) | 2010-08-26 | 2013-10-24 | アッヴィ・インコーポレイテッド | 二重可変ドメイン免疫グロブリンおよびその使用 |
AU2012321082B2 (en) * | 2011-12-01 | 2015-03-12 | Oxurion NV | Improving trabeculectomy outcome |
EP2797955A2 (en) | 2011-12-30 | 2014-11-05 | AbbVie Inc. | Dual variable domain immunoglobulins against il-13 and/or il-17 |
KR20210111353A (ko) | 2012-11-01 | 2021-09-10 | 애브비 인코포레이티드 | 항-vegf/dll4 이원 가변 도메인 면역글로불린 및 이의 용도 |
NZ627796A (en) | 2012-12-18 | 2017-07-28 | Icahn School Med Mount Sinai | Influenza virus vaccines and uses thereof |
WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
EP2970459A2 (en) | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Dual specific binding proteins directed against il-1beta and il-17 |
WO2015051159A1 (en) * | 2013-10-02 | 2015-04-09 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
US10093733B2 (en) | 2014-12-11 | 2018-10-09 | Abbvie Inc. | LRP-8 binding dual variable domain immunoglobulin proteins |
JP2018504412A (ja) | 2015-01-23 | 2018-02-15 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン接種レジメン |
TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
CN104930353B (zh) * | 2015-07-10 | 2017-08-15 | 浙江大学 | 一种城市供水管网的调压减漏评估*** |
CA3013808A1 (en) | 2016-03-10 | 2017-09-14 | Thrombogenics Nv | Posterior ocular fibrosis inhibition by antagonizing placental growth factor |
US11266734B2 (en) | 2016-06-15 | 2022-03-08 | Icahn School Of Medicine At Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
WO2018187706A2 (en) * | 2017-04-07 | 2018-10-11 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
CN109134650A (zh) * | 2018-09-10 | 2019-01-04 | 宁波奥丞生物科技有限公司 | 抗人plgf单克隆抗体的制备方法 |
WO2020239934A1 (en) | 2019-05-28 | 2020-12-03 | Vib Vzw | Cd8+ t-cells lacking plexins and their application in cancer treatment |
EP3976650A1 (en) | 2019-05-28 | 2022-04-06 | Vib Vzw | Cancer treatment by targeting plexins in the immune compartment |
WO2020260595A1 (en) | 2019-06-26 | 2020-12-30 | Oncurious Nv | Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent |
EP3936868A1 (en) | 2020-07-10 | 2022-01-12 | Charité - Universitätsmedizin Berlin | A ratio between plgf and sflt1 is predictive for neural invasion in patients suffering from pancreatic cancer |
WO2022063957A1 (en) | 2020-09-24 | 2022-03-31 | Vib Vzw | Biomarker for anti-tumor therapy |
CN112358546B (zh) * | 2020-11-10 | 2022-04-01 | 宁波奥丞生物科技有限公司 | 杂交瘤细胞株9c1、plgf-1单克隆抗体及其应用 |
GB2616177A (en) * | 2020-11-10 | 2023-08-30 | Ningbo Aucheer Biotechnology Co Ltd | Hybridoma cell strain 9C1, PLGF-1 monoclonal antibody, preparation method therefor and application thereof |
AU2021405744A1 (en) | 2020-12-22 | 2023-08-03 | Cobiores Nv | Compounds comprising a tetrapeptidic moiety |
CN113999310A (zh) * | 2020-12-30 | 2022-02-01 | 江苏普若维生物技术有限责任公司 | 一种plgf单克隆抗体、试剂盒、其制备方法和应用 |
WO2022167664A1 (en) | 2021-02-07 | 2022-08-11 | Cobiores Nv | Compounds comprising a tetrapeptidic moiety |
CA3211257A1 (en) | 2021-02-17 | 2022-08-25 | Vib Vzw | Inhibition of slc4a4 in the treatment of cancer |
WO2023118294A1 (en) | 2021-12-22 | 2023-06-29 | Vib Vzw | Inhibition of mitoferrin 2 as means for inhibiting cancer and cancer metastasis |
WO2024033381A1 (en) | 2022-08-10 | 2024-02-15 | Vib Vzw | Inhibition of tcf4/itf2 in the treatment of cancer |
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NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
US5770198A (en) | 1988-05-18 | 1998-06-23 | The Research Foundation Of The State Of New York | Platelet-specific chimeric 7E3 immunoglobulin |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
IT1242149B (it) | 1990-09-27 | 1994-02-16 | Consiglio Nazionale Ricerche | Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi |
EP0633945B1 (en) * | 1992-04-03 | 1998-12-30 | Genentech, Inc. | ANTIBODIES TO ALPHAvBETA3 INTEGRIN |
US6177401B1 (en) | 1992-11-13 | 2001-01-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften | Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis |
US5861499A (en) * | 1994-02-10 | 1999-01-19 | Imclone Systems Incorporated | Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain |
IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
JP2000507915A (ja) | 1995-10-23 | 2000-06-27 | ハイアル・ファーマシューティカル・オーストラリア・リミテッド | 遺伝子療法のためのdna担体としてのヒアルロン酸および異常な網膜血管新生を治療するためのvegfアンチセンスdna |
EP0928203B1 (en) | 1996-09-24 | 2006-10-25 | Merck & Co., Inc. | Compounds for the inhibition of angiogenesis by gene therapy |
US6986890B1 (en) * | 1996-11-21 | 2006-01-17 | Kyowa Hakko Kogyo Co., Ltd. | Anti-human VEGF receptor Flt-1 monoclonal antibody |
US6455283B1 (en) * | 1998-03-17 | 2002-09-24 | Genentech, Inc. | Nucleic acids encoding vascular endothelial cell growth factor-E (VEGF-E) |
GB9723780D0 (en) | 1997-11-12 | 1998-01-07 | Univ Manchester | Regulation of ocular angiogenesis |
JPH11302193A (ja) * | 1998-04-22 | 1999-11-02 | Toagosei Co Ltd | 血管新生阻害剤 |
AU751647B2 (en) | 1998-05-26 | 2002-08-22 | Innogenetics N.V. | Method for expanding primate B cells selectively in immunocompromised mice and producing large numbers of antigen-specific B lymphocytes for the production of primate monoclonal antibodies |
JP2001086982A (ja) | 1999-07-16 | 2001-04-03 | Shunpei Niida | 骨吸収調節薬 |
JP2003528824A (ja) * | 2000-02-04 | 2003-09-30 | スプラテック ファーマ インコーポレイティド | 血管内皮成長因子受容体のためのリガンド |
WO2001085796A2 (en) * | 2000-05-12 | 2001-11-15 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Use of inhibitors of placental growth factor for the treatment of pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage |
WO2002097044A2 (en) * | 2001-05-25 | 2002-12-05 | Thomas Jefferson University | Alternative splice forms of proteins as basis for multiple therapeutic modalities |
US7139817B1 (en) * | 2001-06-12 | 2006-11-21 | Network Appliance, Inc. | Managing configuration information for multiple devices |
US20040247597A1 (en) | 2001-06-20 | 2004-12-09 | Peter Carmeliet | Method of treating atherosclerosis and other inflammatory diseases |
US20050163781A1 (en) | 2002-01-29 | 2005-07-28 | Philippe Koninckx | Tissue adhesion formation control |
JP5111729B2 (ja) | 2002-06-05 | 2013-01-09 | ジェネンテック, インコーポレイテッド | 肝成長及び肝保護のための組成物と方法 |
US7357929B2 (en) * | 2002-06-28 | 2008-04-15 | D. Collen Research Foundation Vzw | Placental growth factor as a target for the treatment of osteoporosis |
WO2004042085A2 (en) * | 2002-11-08 | 2004-05-21 | Primagen Holding B.V. | Method for quantifying a ratio between at least two nucleic acid sequences |
JP2006519842A (ja) * | 2003-03-10 | 2006-08-31 | カリスト・ファーマシューティカルズ・インコーポレイテッド | アザスピラン化合物による癌治療法 |
WO2005087812A1 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for vegf/pdgf family of growth factors |
CA2601267C (en) | 2005-03-24 | 2014-02-18 | Thromb-X N.V. | Novel anti-plgf antibody |
EP1904095B1 (en) | 2005-06-30 | 2013-05-29 | VIB, vzw | Treatment of liver cirrhosis and its complications |
CA2736929C (en) | 2008-10-02 | 2019-02-26 | Life Sciences Research Partners Vzw | Inhibition of plgf to treat philadelphia chromosome positive leukemia |
-
2006
- 2006-03-24 CA CA2601267A patent/CA2601267C/en not_active Expired - Fee Related
- 2006-03-24 EA EA200702064A patent/EA013970B1/ru not_active IP Right Cessation
- 2006-03-24 DK DK06721544.2T patent/DK1869085T3/da active
- 2006-03-24 CN CN2006800093279A patent/CN101184776B/zh not_active Expired - Fee Related
- 2006-03-24 KR KR1020077024317A patent/KR101314014B1/ko active IP Right Grant
- 2006-03-24 AT AT06721544T patent/ATE549358T1/de active
- 2006-03-24 UA UAA200711730A patent/UA94707C2/ru unknown
- 2006-03-24 SI SI200631343T patent/SI1869085T1/sl unknown
- 2006-03-24 MX MX2007011735A patent/MX2007011735A/es active IP Right Grant
- 2006-03-24 JP JP2008502194A patent/JP5164829B2/ja not_active Expired - Fee Related
- 2006-03-24 ME MEP-2012-73A patent/ME01446B/me unknown
- 2006-03-24 AU AU2006227571A patent/AU2006227571B8/en not_active Ceased
- 2006-03-24 BR BRPI0609151A patent/BRPI0609151B8/pt not_active IP Right Cessation
- 2006-03-24 ES ES11160897.2T patent/ES2565481T3/es active Active
- 2006-03-24 NZ NZ561763A patent/NZ561763A/en unknown
- 2006-03-24 ES ES06721544T patent/ES2384110T3/es active Active
- 2006-03-24 EP EP11160897.2A patent/EP2447281B1/en not_active Not-in-force
- 2006-03-24 US US11/909,604 patent/US7875704B2/en not_active Expired - Fee Related
- 2006-03-24 PT PT06721544T patent/PT1869085E/pt unknown
- 2006-03-24 RS RS20120249A patent/RS52372B/en unknown
- 2006-03-24 PL PL06721544T patent/PL1869085T3/pl unknown
- 2006-03-24 WO PCT/BE2006/000023 patent/WO2006099698A2/en active Application Filing
- 2006-03-24 ZA ZA200707258A patent/ZA200707258B/xx unknown
- 2006-03-24 EP EP06721544A patent/EP1869085B1/en active Active
-
2007
- 2007-09-05 IL IL185754A patent/IL185754A/en active IP Right Grant
- 2007-09-10 NO NO20074563A patent/NO341877B1/no not_active IP Right Cessation
-
2008
- 2008-03-11 HK HK08102805.3A patent/HK1116803A1/xx not_active IP Right Cessation
-
2010
- 2010-12-20 US US12/973,155 patent/US8758748B2/en active Active
-
2011
- 2011-03-23 AU AU2011201340A patent/AU2011201340B2/en not_active Ceased
-
2012
- 2012-02-01 JP JP2012019698A patent/JP2012136522A/ja active Pending
- 2012-06-06 HR HRP20120477TT patent/HRP20120477T1/hr unknown
- 2012-06-12 CY CY20121100535T patent/CY1113224T1/el unknown
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2014
- 2014-02-03 US US14/170,997 patent/US9085617B2/en not_active Expired - Fee Related
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