HK1129388A1 - Human protein-tyrosine phosphatase inhibitors and their pharmaceutical use - Google Patents

Human protein-tyrosine phosphatase inhibitors and their pharmaceutical use

Info

Publication number
HK1129388A1
HK1129388A1 HK09108321.4A HK09108321A HK1129388A1 HK 1129388 A1 HK1129388 A1 HK 1129388A1 HK 09108321 A HK09108321 A HK 09108321A HK 1129388 A1 HK1129388 A1 HK 1129388A1
Authority
HK
Hong Kong
Prior art keywords
human protein
pharmaceutical use
tyrosine phosphatase
phosphatase inhibitors
inhibitors
Prior art date
Application number
HK09108321.4A
Other languages
English (en)
Chinese (zh)
Inventor
Jeffrey Lyle Gray
Cynthia Monesa Clark
Kande Amarasinghe
Mathew Brian Maier
Ryan Nichols
Original Assignee
Aerpio Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38704718&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1129388(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aerpio Therapeutics Inc filed Critical Aerpio Therapeutics Inc
Publication of HK1129388A1 publication Critical patent/HK1129388A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
HK09108321.4A 2006-06-27 2009-09-10 Human protein-tyrosine phosphatase inhibitors and their pharmaceutical use HK1129388A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81682506P 2006-06-27 2006-06-27
PCT/US2007/014824 WO2008002571A2 (en) 2006-06-27 2007-06-27 Human protein tyrosine phosphatase inhibitors and methods of use

Publications (1)

Publication Number Publication Date
HK1129388A1 true HK1129388A1 (en) 2009-11-27

Family

ID=38704718

Family Applications (2)

Application Number Title Priority Date Filing Date
HK09108321.4A HK1129388A1 (en) 2006-06-27 2009-09-10 Human protein-tyrosine phosphatase inhibitors and their pharmaceutical use
HK15104703.3A HK1203960A1 (en) 2006-06-27 2015-05-18 Human protein tyrosine phosphatase inhibitors and their pharmaceutical use

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15104703.3A HK1203960A1 (en) 2006-06-27 2015-05-18 Human protein tyrosine phosphatase inhibitors and their pharmaceutical use

Country Status (23)

Country Link
US (3) US7589212B2 (tr)
EP (3) EP2041129B1 (tr)
JP (1) JP5201740B2 (tr)
KR (1) KR101157844B1 (tr)
CN (1) CN101506204B (tr)
AU (1) AU2007265455B2 (tr)
BR (1) BRPI0713349A2 (tr)
CA (1) CA2656915C (tr)
CO (1) CO6150143A2 (tr)
CY (1) CY1115588T1 (tr)
DK (2) DK2041129T3 (tr)
ES (2) ES2510674T3 (tr)
HK (2) HK1129388A1 (tr)
IL (1) IL196130A (tr)
MX (1) MX2009000290A (tr)
NZ (1) NZ574405A (tr)
PL (2) PL2803663T3 (tr)
PT (2) PT2803663T (tr)
RU (1) RU2430101C2 (tr)
SI (1) SI2041129T1 (tr)
TR (1) TR201802280T4 (tr)
WO (1) WO2008002571A2 (tr)
ZA (1) ZA200900558B (tr)

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MX2008012991A (es) 2006-04-07 2008-10-17 Procter & Gamble Anticuerpos que ligan proteina tirosina fosfatasa humana beta (hptpbeta) y los usos de estos.
US7589212B2 (en) 2006-06-27 2009-09-15 Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US7795444B2 (en) * 2006-06-27 2010-09-14 Warner Chilcott Company Human protein tyrosine phosphatase inhibitors and methods of use
US8846685B2 (en) 2006-06-27 2014-09-30 Aerpio Therapeutics Inc. Human protein tyrosine phosphatase inhibitors and methods of use
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US9096555B2 (en) 2009-01-12 2015-08-04 Aerpio Therapeutics, Inc. Methods for treating vascular leak syndrome
AU2011312203C1 (en) * 2009-01-12 2016-09-08 EyePoint Pharmaceuticals, Inc. Compositions and methods for treating ocular edema, neovascularization and related diseases
TR201809280T4 (tr) * 2009-01-12 2018-07-23 Aerpio Therapeutics Inc Vasküler sızıntı sendromunun tedavi edilmesine yönelik yöntemler.
AU2016203254B2 (en) * 2009-01-12 2018-09-13 EyePoint Pharmaceuticals, Inc. Methods for treating vascular leak syndrome
AU2014202211B2 (en) * 2009-01-12 2016-06-02 EyePoint Pharmaceuticals, Inc. Methods for treating vascular leak syndrome
US8883832B2 (en) 2009-07-06 2014-11-11 Aerpio Therapeutics Inc. Compounds, compositions, and methods for preventing metastasis of cancer cells
PT2451279T (pt) 2009-07-06 2019-06-18 Aerpio Therapeutics Inc Derivados de benzosulfonamida, composições dos mesmos, e uso dos mesmos na prevenção de metástases de células cancerígenas
EP2954899B1 (en) 2009-11-06 2020-01-08 Aerpio Therapeutics, Inc. Compositions and methods for treating colitis
CN104066448A (zh) 2011-10-13 2014-09-24 阿尔皮奥治疗学股份有限公司 眼病的治疗
AU2012323856B2 (en) 2011-10-13 2017-05-25 EyePoint Pharmaceuticals, Inc. Methods for treating Vascular Leak Syndrome and cancer
RU2507597C2 (ru) * 2012-05-23 2014-02-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации Способ фармакологической коррекции ишемии скелетной мышцы никорандилом
US20150050277A1 (en) 2013-03-15 2015-02-19 Aerpio Therapeutics Inc. Compositions and methods for treating ocular diseases
GB2549865B (en) 2013-03-15 2018-01-17 Aerpio Therapeutics Inc Formulations comprising a compound that activates Tie-2 and their use in treating ocular diseases
RU2526466C1 (ru) * 2013-04-04 2014-08-20 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт кардиологии" Сибирского отделения Российской академии медицинских наук Средство для стимуляции васкуляризации сердечной мышцы при постинфарктном ее ремоделировании в эксперименте
WO2015126860A1 (en) 2014-02-19 2015-08-27 Aerpio Therapeutics, Inc. Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-ones
JP6483148B2 (ja) * 2014-03-14 2019-03-13 エアーピオ セラピューティクス インコーポレイテッド ＨＰＴＰ−β阻害剤
US9539245B2 (en) 2014-08-07 2017-01-10 Aerpio Therapeutics, Inc. Combination of immunotherapies with activators of Tie-2
JP6959924B2 (ja) 2015-09-23 2021-11-05 エアーピオ ファーマシューティカルズ， インコーポレイテッド Ｔｉｅ−２の活性化物質を用いる眼内圧を処置する方法
SG11201900464TA (en) 2016-07-20 2019-02-27 Aerpio Therapeutics Inc HUMANIZED MONOCLONAL ANTIBODIES THAT TARGET VE-PTP (HPTP-ß)
CN109996440A (zh) * 2016-10-21 2019-07-09 曼宁研究有限公司 Ve-ptp敲除
US10900319B2 (en) 2017-12-14 2021-01-26 Exacta-Frac Energy Services, Inc. Cased bore straddle packer
EP3856245A4 (en) 2018-09-24 2022-10-26 EyePoint Pharmaceuticals, Inc. MULTISPECIFIC ANTIBODIES TARGETING HPTP-ß (VE-PTP) AND VEGF
CA3138682A1 (en) 2019-04-29 2020-11-05 EyePoint Pharmaceuticals, Inc. Tie-2 activators targeting the schlemm's canal
US11413242B2 (en) 2019-06-24 2022-08-16 EyePoint Pharmaceuticals, Inc. Formulations of Tie-2 activators and methods of use thereof
US11613534B2 (en) 2019-10-29 2023-03-28 EyePoint Pharmaceuticals, Inc. Small molecule activators of Tie-2
CN117343052B (zh) * 2023-12-04 2024-02-06 英矽智能科技(上海)有限公司 蛋白酪氨酸磷酸酶抑制剂及其应用

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US7622593B2 (en) * 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US7795444B2 (en) * 2006-06-27 2010-09-14 Warner Chilcott Company Human protein tyrosine phosphatase inhibitors and methods of use
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PT2451279T (pt) 2009-07-06 2019-06-18 Aerpio Therapeutics Inc Derivados de benzosulfonamida, composições dos mesmos, e uso dos mesmos na prevenção de metástases de células cancerígenas

Also Published As

Publication number Publication date
NZ574405A (en) 2012-01-12
ES2510674T3 (es) 2014-10-21
JP5201740B2 (ja) 2013-06-05
EP2041129B1 (en) 2014-09-03
WO2008002571A2 (en) 2008-01-03
EP2803663A1 (en) 2014-11-19
DK2041129T3 (da) 2014-10-13
PL2803663T3 (pl) 2018-05-30
CY1115588T1 (el) 2017-01-04
AU2007265455A2 (en) 2009-05-21
JP2009542660A (ja) 2009-12-03
ZA200900558B (en) 2012-04-24
HK1203960A1 (en) 2015-11-06
CA2656915C (en) 2012-08-07
AU2007265455B2 (en) 2011-11-10
US20120077853A1 (en) 2012-03-29
KR101157844B1 (ko) 2012-06-22
IL196130A0 (en) 2009-09-22
US20070299116A1 (en) 2007-12-27
TR201802280T4 (tr) 2018-03-21
KR20090024296A (ko) 2009-03-06
EP3287455A1 (en) 2018-02-28
SI2041129T1 (sl) 2014-11-28
PL2041129T3 (pl) 2014-11-28
CN101506204B (zh) 2012-05-30
WO2008002571A3 (en) 2008-02-14
PT2803663T (pt) 2018-02-28
ES2660571T3 (es) 2018-03-23
BRPI0713349A2 (pt) 2012-03-06
WO2008002571B1 (en) 2008-04-17
RU2009102537A (ru) 2010-08-10
US8188125B2 (en) 2012-05-29
CN101506204A (zh) 2009-08-12
US20090227639A1 (en) 2009-09-10
US7589212B2 (en) 2009-09-15
CA2656915A1 (en) 2008-01-03
DK2803663T3 (en) 2018-03-05
PT2041129E (pt) 2014-10-08
EP2041129A2 (en) 2009-04-01
AU2007265455A1 (en) 2008-01-03
EP2803663B1 (en) 2017-11-29
IL196130A (en) 2014-04-30
CO6150143A2 (es) 2010-04-20
RU2430101C2 (ru) 2011-09-27
MX2009000290A (es) 2009-03-16
US8338615B2 (en) 2012-12-25

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Legal Events

Date Code Title Description
CHRG Changes in the register

Free format text: CORRECTION OF THE NAME OF APPLICANT/PROPRIETOR FROM AERPIO THERAPEUTICS INC. TO AERPIO THERAPEUTICS, INC.

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230625