DE69332197T2 - Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmenten - Google Patents

Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmenten

Info

Publication number
DE69332197T2
DE69332197T2 DE69332197T DE69332197T DE69332197T2 DE 69332197 T2 DE69332197 T2 DE 69332197T2 DE 69332197 T DE69332197 T DE 69332197T DE 69332197 T DE69332197 T DE 69332197T DE 69332197 T2 DE69332197 T2 DE 69332197T2
Authority
DE
Germany
Prior art keywords
nucleic acid
ebv
epstein
peptides
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332197T
Other languages
English (en)
Other versions
DE69332197D1 (de
Inventor
J M Middeldorp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux BV
Original Assignee
Organon Teknika BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Teknika BV filed Critical Organon Teknika BV
Publication of DE69332197D1 publication Critical patent/DE69332197D1/de
Application granted granted Critical
Publication of DE69332197T2 publication Critical patent/DE69332197T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56994—Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE69332197T 1992-03-13 1993-03-10 Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmenten Expired - Lifetime DE69332197T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92200721 1992-03-13

Publications (2)

Publication Number Publication Date
DE69332197D1 DE69332197D1 (de) 2002-09-19
DE69332197T2 true DE69332197T2 (de) 2003-04-17

Family

ID=8210477

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69332197T Expired - Lifetime DE69332197T2 (de) 1992-03-13 1993-03-10 Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmenten
DE69334191T Expired - Lifetime DE69334191T2 (de) 1992-03-13 1993-03-10 Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmente

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69334191T Expired - Lifetime DE69334191T2 (de) 1992-03-13 1993-03-10 Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmente

Country Status (13)

Country Link
US (1) US5424398A (de)
EP (2) EP1225226B1 (de)
JP (3) JP4135996B2 (de)
KR (1) KR100291247B1 (de)
AT (2) ATE222291T1 (de)
AU (1) AU666920B2 (de)
CA (1) CA2092680C (de)
DE (2) DE69332197T2 (de)
DK (2) DK0574048T3 (de)
ES (2) ES2184735T3 (de)
FI (1) FI114802B (de)
PT (1) PT574048E (de)
ZA (1) ZA931797B (de)

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ES2191673T3 (es) * 1993-09-14 2003-09-16 Biomerieux Bv Reactivos de diagnostico para la deteccion de anticuerpos contra el virus de epstein barr.
US5834747A (en) * 1994-11-04 1998-11-10 Pixel Instruments Universal credit card apparatus and method
DE19526384C2 (de) * 1995-07-19 1997-07-10 Biotest Ag Rekombinante autologe Fusionsproteine des Epstein-Barr-Virus, sowie diese enthaltende Testkits zum Nachweis von Epstein-Barr-Virus-spezifischen Antikörpern
US5813500A (en) * 1996-03-25 1998-09-29 Tenneco Automotive Inc. Anti-swish mechanism for a damper
FR2765688B1 (fr) 1997-07-04 1999-09-10 Pasteur Institut Reactif de detection et de suivi des infections provoquees par le virus d'epstein-barr et ses applications
US6797691B1 (en) 1997-07-23 2004-09-28 Northwestern University Methods and compositions for inhibiting angiogenesis
US7105496B2 (en) * 1998-07-23 2006-09-12 Northwestern University Methods and compositions for inhibiting angiogenesis
EP1627886A1 (de) * 1997-10-07 2006-02-22 Ono Pharmaceutical Co., Ltd. Polypeptide, die dafür kodierende cDNA und deren Verwendung
ES2323562T3 (es) * 1998-03-04 2009-07-20 Biomerieux B.V. Amplificacion y deteccion de la expresion ebv-barf1 para el diagnostico del carcinoma nasofaringeo.
US20030064917A1 (en) * 1998-07-23 2003-04-03 Crawford Susan E. Methods and compositions for inhibiting angiogenesis
US6159950A (en) * 1998-10-16 2000-12-12 Cornell Research Foundation, Inc. Method of modulating hair growth
DE60131146T2 (de) * 2000-02-25 2008-03-06 Ludwig Institute For Cancer Research Material und verfahren die hybridvaskularendothelwachstumfaktoren dns und proteine enthalten und screeningverfahren für modulatoren
WO2003033520A2 (en) * 2001-09-24 2003-04-24 University Of Pittburgh Of The Commonwealth System Of Higher Education Anticancer vaccine and diganostic methods and reagents
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
JP2005530716A (ja) * 2002-03-27 2005-10-13 アメリカ合衆国 ヒトにおける癌の治療方法
US7226755B1 (en) * 2002-09-25 2007-06-05 The Procter & Gamble Company HPTPbeta as a target in treatment of angiogenesis mediated disorders
US7507568B2 (en) * 2002-09-25 2009-03-24 The Proctor & Gamble Company Three dimensional coordinates of HPTPbeta
US6886670B2 (en) * 2003-09-29 2005-05-03 Tenneco Automotive Operating Company Inc. Extra support land for valve disc
DE10307517A1 (de) * 2003-02-21 2004-09-02 Mikrogen Molekularbiologische Entwicklungs-Gmbh Von Kapsidantigenen des Epstein-Barr-Virus abgeleitete Peptide und ihre Verwendung
US6899207B2 (en) 2003-09-29 2005-05-31 Tenneco Automotive Operating Company Inc. Extra support area for valve disc
AU2005255019B2 (en) * 2004-06-12 2011-05-19 Oregon Health And Science University Compositions and methods for diagnosis and treatment of orthopoxviruses
US7278987B2 (en) * 2004-07-09 2007-10-09 Anthony Solazzo Ergonomic urological catheterization/irrigation tray
WO2007044033A2 (en) 2004-12-07 2007-04-19 University Of Pittsburgh Of The Commonwealth System Of Higher Education Therapeutic and diagnostic cloned mhc-unrestricted receptor specific for the muc1 tumor associated antigen
EP2311532A1 (de) 2005-12-01 2011-04-20 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services Antivirale Griffithsin-Verbindungen, Zusammensetzungen und Verwendungsverfahren dafür
WO2007071448A2 (en) 2005-12-23 2007-06-28 Partnership & Corp. Technology Transfer Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of muscle relaxation
US7868228B2 (en) 2006-01-31 2011-01-11 Monsanto Technology Llc Phosphopantetheinyl transferases from bacteria
MX2008012991A (es) 2006-04-07 2008-10-17 Procter & Gamble Anticuerpos que ligan proteina tirosina fosfatasa humana beta (hptpbeta) y los usos de estos.
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US7589212B2 (en) 2006-06-27 2009-09-15 Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US8846685B2 (en) 2006-06-27 2014-09-30 Aerpio Therapeutics Inc. Human protein tyrosine phosphatase inhibitors and methods of use
US7795444B2 (en) * 2006-06-27 2010-09-14 Warner Chilcott Company Human protein tyrosine phosphatase inhibitors and methods of use
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
AU2009262199B2 (en) 2008-06-27 2012-08-09 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
WO2010011994A2 (en) 2008-07-25 2010-01-28 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Polypeptides and uses thereof
EP2337791B1 (de) 2008-10-14 2013-07-24 Monsanto Technology LLC Verwendung von fettsäuredesaturasen aus hemiselmis spp
US9096555B2 (en) 2009-01-12 2015-08-04 Aerpio Therapeutics, Inc. Methods for treating vascular leak syndrome
US8883832B2 (en) 2009-07-06 2014-11-11 Aerpio Therapeutics Inc. Compounds, compositions, and methods for preventing metastasis of cancer cells
CA2748765C (en) 2009-07-06 2014-07-22 Akebia Therapeutics Inc. Compounds, compositions, and methods for preventing metastasis of cancer cells
US20120100166A1 (en) 2010-07-15 2012-04-26 Zyngenia, Inc. Ang-2 Binding Complexes and Uses Thereof
CA2827170A1 (en) 2011-02-11 2012-08-16 David M. Hilbert Monovalent and multivalent multispecific complexes and uses thereof
CN103857699B (zh) 2011-05-24 2016-08-31 泽恩格尼亚股份有限公司 多价和单价多特异性复合物及其用途
WO2013025479A1 (en) 2011-08-16 2013-02-21 Emory University Jaml specific binding agents, antibodies, and uses related thereto
CA2907181C (en) 2013-03-15 2023-10-17 Viktor Roschke Multivalent and monovalent multispecific complexes and their uses
EP2813849A1 (de) * 2013-06-10 2014-12-17 Charité-Universitätsmedizin Berlin (Charité) EBV-spezifische Immunsignatur als Diagnosemarker bei chronischem Erschöpfungssyndrom (CFS)
AU2015204680B2 (en) 2014-01-09 2019-07-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-viral cnidarins
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EP3256144B1 (de) 2015-02-13 2021-03-24 The Board of Trustees of the University of Illionis Peptidhemmung von ccr3-vermittelten krankheiten oder zuständen
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JP2018533578A (ja) 2015-10-30 2018-11-15 モナシュ ユニバーシティー グルコース代謝改善のための方法及び組成物
CN108490177B (zh) * 2018-02-08 2020-12-29 深圳市新产业生物医学工程股份有限公司 鼻咽癌抗体检测试剂、其制备方法及鼻咽癌检测试剂盒
WO2021021774A1 (en) 2019-07-29 2021-02-04 The Board Of Trustees Of The University Of Illinois Composition and method for promoting wound healing
CN114846024A (zh) 2019-12-20 2022-08-02 豪夫迈·罗氏有限公司 Il-37融合蛋白及其用途
WO2022109053A1 (en) 2020-11-18 2022-05-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tyrosyl-lock peptides
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Also Published As

Publication number Publication date
FI114802B (fi) 2004-12-31
CA2092680C (en) 2006-08-08
CA2092680A1 (en) 1993-09-14
AU666920B2 (en) 1996-02-29
EP0574048A3 (de) 1994-03-02
DE69334191T2 (de) 2008-11-27
KR930019829A (ko) 1993-10-19
ES2184735T3 (es) 2003-04-16
ATE380243T1 (de) 2007-12-15
JP4106041B2 (ja) 2008-06-25
KR100291247B1 (ko) 2001-06-01
DK1225226T3 (da) 2008-04-14
ZA931797B (en) 1993-09-30
ES2298325T3 (es) 2008-05-16
DE69332197D1 (de) 2002-09-19
JPH0690787A (ja) 1994-04-05
EP1225226B1 (de) 2007-12-05
FI931109A (fi) 1993-09-14
AU3515293A (en) 1993-09-16
JP4135996B2 (ja) 2008-08-20
PT574048E (pt) 2002-12-31
JP4365440B2 (ja) 2009-11-18
JP2008261851A (ja) 2008-10-30
JP2004261183A (ja) 2004-09-24
EP0574048B1 (de) 2002-08-14
DK0574048T3 (da) 2002-12-16
EP1225226A1 (de) 2002-07-24
DE69334191D1 (de) 2008-01-17
US5424398A (en) 1995-06-13
EP0574048A2 (de) 1993-12-15
FI931109A0 (fi) 1993-03-12
ATE222291T1 (de) 2002-08-15

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