HK1042299B - 多環的噻唑-2-亞基胺、它們的製備方法和它們作為藥物的用途 - Google Patents

多環的噻唑-2-亞基胺、它們的製備方法和它們作為藥物的用途

Info

Publication number
HK1042299B
HK1042299B HK02104046.4A HK02104046A HK1042299B HK 1042299 B HK1042299 B HK 1042299B HK 02104046 A HK02104046 A HK 02104046A HK 1042299 B HK1042299 B HK 1042299B
Authority
HK
Hong Kong
Prior art keywords
medicaments
utilization
production
amines
polycyclic
Prior art date
Application number
HK02104046.4A
Other languages
English (en)
Other versions
HK1042299A1 (en
Inventor
G‧傑恩
K‧蓋森
H-J‧蘭格
M‧畢克爾
Original Assignee
阿文蒂斯藥物德國有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 阿文蒂斯藥物德國有限公司 filed Critical 阿文蒂斯藥物德國有限公司
Publication of HK1042299A1 publication Critical patent/HK1042299A1/xx
Publication of HK1042299B publication Critical patent/HK1042299B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK02104046.4A 1999-02-26 2002-05-31 多環的噻唑-2-亞基胺、它們的製備方法和它們作為藥物的用途 HK1042299B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19908536A DE19908536A1 (de) 1999-02-26 1999-02-26 Polycyclische Thiazol-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP2000/000926 WO2000051996A1 (de) 1999-02-26 2000-02-05 Polycyclische thiazol-2-yliden amine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
HK1042299A1 HK1042299A1 (en) 2002-08-09
HK1042299B true HK1042299B (zh) 2004-12-10

Family

ID=7899080

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02104046.4A HK1042299B (zh) 1999-02-26 2002-05-31 多環的噻唑-2-亞基胺、它們的製備方法和它們作為藥物的用途

Country Status (15)

Country Link
US (3) US6207689B1 (zh)
EP (1) EP1157013B1 (zh)
JP (1) JP2002538149A (zh)
KR (1) KR20010102365A (zh)
CN (1) CN1152027C (zh)
AT (1) ATE284394T1 (zh)
AU (1) AU765300B2 (zh)
BR (1) BR0008559A (zh)
CA (1) CA2364902A1 (zh)
DE (2) DE19908536A1 (zh)
ES (1) ES2232425T3 (zh)
HK (1) HK1042299B (zh)
PT (1) PT1157013E (zh)
WO (1) WO2000051996A1 (zh)
ZA (1) ZA200106441B (zh)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507868A (en) * 1968-10-21 1970-04-21 Sandoz Ag Imidazo(2,1-b)thiazoles and thiazolo(3,2-a)pyrimidines
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
IT1204959B (it) * 1987-03-25 1989-03-10 Zambon Farmaceutici Spa Composti dotati di attivita' antiallergica
GB9513467D0 (en) * 1995-07-01 1995-09-06 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
JP2002538149A (ja) 2002-11-12
AU2802200A (en) 2000-09-21
DE19908536A1 (de) 2000-08-31
US20010011096A1 (en) 2001-08-02
BR0008559A (pt) 2001-12-18
EP1157013A1 (de) 2001-11-28
US6207689B1 (en) 2001-03-27
DE50008905D1 (de) 2005-01-13
ZA200106441B (en) 2002-02-13
WO2000051996A1 (de) 2000-09-08
ES2232425T3 (es) 2005-06-01
EP1157013B1 (de) 2004-12-08
HK1042299A1 (en) 2002-08-09
ATE284394T1 (de) 2004-12-15
KR20010102365A (ko) 2001-11-15
US6288094B2 (en) 2001-09-11
CN1152027C (zh) 2004-06-02
CN1341109A (zh) 2002-03-20
PT1157013E (pt) 2005-02-28
CA2364902A1 (en) 2000-09-08
US6288093B1 (en) 2001-09-11
AU765300B2 (en) 2003-09-11

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080205