HK1010785A1 - Therapeutic peptides - Google Patents

Therapeutic peptides

Info

Publication number
HK1010785A1
HK1010785A1 HK98111817A HK98111817A HK1010785A1 HK 1010785 A1 HK1010785 A1 HK 1010785A1 HK 98111817 A HK98111817 A HK 98111817A HK 98111817 A HK98111817 A HK 98111817A HK 1010785 A1 HK1010785 A1 HK 1010785A1
Authority
HK
Hong Kong
Prior art keywords
active site
binding
peptide
receptor
analog
Prior art date
Application number
HK98111817A
Other languages
English (en)
Inventor
David H Coy
Jacques-Pierre Moreau
John E Taylor
Sun Hyuk Kim
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/282,328 external-priority patent/US5162497A/en
Application filed by Univ Tulane filed Critical Univ Tulane
Publication of HK1010785A1 publication Critical patent/HK1010785A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57572—Gastrin releasing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK98111817A 1988-10-14 1998-11-06 Therapeutic peptides HK1010785A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US25799888A 1988-10-14 1988-10-14
US07/282,328 US5162497A (en) 1987-09-24 1988-12-09 Bradykinin analogs with non-peptide bond
US31794189A 1989-03-02 1989-03-02
US37655589A 1989-07-07 1989-07-07
US39716989A 1989-08-21 1989-08-21
PCT/US1989/004616 WO1990003980A1 (en) 1988-10-14 1989-10-13 Therapeutic peptides

Publications (1)

Publication Number Publication Date
HK1010785A1 true HK1010785A1 (en) 1999-06-25

Family

ID=27540392

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98111817A HK1010785A1 (en) 1988-10-14 1998-11-06 Therapeutic peptides

Country Status (13)

Country Link
EP (1) EP0438519B1 (xx)
JP (1) JP2919889B2 (xx)
KR (1) KR900701827A (xx)
AT (1) ATE165836T1 (xx)
AU (1) AU638423B2 (xx)
DE (1) DE68928667T2 (xx)
DK (1) DK66391A (xx)
FI (1) FI104252B (xx)
HK (1) HK1010785A1 (xx)
HU (1) HU208439B (xx)
MC (1) MC2144A1 (xx)
TW (1) TW201754B (xx)
WO (1) WO1990003980A1 (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2877775A (en) * 1957-12-23 1959-03-17 Preston M Hall Rotary type filing and abrading appliance
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
US6218364B1 (en) 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
WO1991004040A1 (en) * 1989-09-15 1991-04-04 Biomeasure, Inc. Treatment of colon cancer
CA2045494A1 (en) * 1989-11-06 1991-05-07 Luigia Gozzini Reduced irreversible bombesin antagonists
AU641789B2 (en) * 1990-07-26 1993-09-30 Aventisub Ii Inc. Peptides
US5834433A (en) * 1990-07-26 1998-11-10 Merrell Pharmaceuticals Inc. Compounds and pharmaceutical uses of peptides of bombesin and GRP
US5369094A (en) * 1990-11-29 1994-11-29 The Administrators Of The Tulane Educational Fund Polypeptide bombesin antagonists
US5244883A (en) * 1990-11-29 1993-09-14 The Administrators Of The Tulane Educational Fund Nonapeptide bombesin antagonists
JP3350701B2 (ja) * 1991-05-23 2002-11-25 メレルダウファーマスーティカルズ インコーポレイテッド ボンベシン類似体類
CA2129032A1 (en) * 1992-02-07 1993-08-19 Judson V. Edwards Phenylalanine analogs of bombesin
DE4320201A1 (de) * 1993-06-18 1995-01-12 Asta Medica Ag Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation
FR2739553B1 (fr) 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US6492330B1 (en) 1996-08-16 2002-12-10 National Institute Of Immunology Antiangiogenic drugs
US6156725A (en) * 1996-08-16 2000-12-05 National Institute Of Immunology Drug for the treatment of cancer
US8420050B2 (en) 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7922998B2 (en) 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
NZ576739A (en) 2003-04-22 2011-01-28 Sod Conseils Rech Applic Peptide vectors for delivering paclitaxel
RU2009112716A (ru) * 2006-09-08 2010-10-20 Байер Шеринг Фарма Акциенгезельшафт (DE) Соединения и способы для агентов, меченых 18f
EP2310028B1 (en) 2008-06-12 2016-11-16 Ipsen Bioinnovation Limited Fusion proteins for use in the treatment of acromegaly
CN107446053A (zh) 2008-06-12 2017-12-08 益普生生物创新有限公司 癌症的抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2198878A1 (en) 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists
CN116333041A (zh) * 2023-04-10 2023-06-27 湖南中晟全肽生化有限公司 一种激活grp受体的多肽化合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207311A (en) 1977-07-18 1980-06-10 The Salk Institute For Biological Studies Peptides having analgesic and thermoregulative properties
US4331611A (en) 1979-12-21 1982-05-25 International Flavors & Fragrances Inc. Nitrile and uses of same in perfumes, colognes and perfumed articles
US4331661A (en) * 1980-10-03 1982-05-25 The Salk Institute For Biological Studies Bombesin analogs
US4613586A (en) * 1984-04-19 1986-09-23 Board Of Trustees Of The Leland Stanford Junior University Gastrin releasing peptide-like peptides
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide

Also Published As

Publication number Publication date
TW201754B (xx) 1993-03-11
AU4494989A (en) 1990-05-01
HU208439B (en) 1993-10-28
EP0438519A1 (en) 1991-07-31
EP0438519B1 (en) 1998-05-06
FI104252B1 (fi) 1999-12-15
DE68928667D1 (de) 1998-06-10
DE68928667T2 (de) 1998-10-01
DK66391D0 (da) 1991-04-12
FI911780A0 (fi) 1991-04-12
KR900701827A (ko) 1990-12-04
AU638423B2 (en) 1993-07-01
JPH04504406A (ja) 1992-08-06
DK66391A (da) 1991-06-14
JP2919889B2 (ja) 1999-07-19
FI104252B (fi) 1999-12-15
HU896391D0 (en) 1991-07-29
HUT59420A (en) 1992-05-28
EP0438519A4 (en) 1991-10-30
MC2144A1 (fr) 1992-02-19
WO1990003980A1 (en) 1990-04-19
ATE165836T1 (de) 1998-05-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)