HK1002632A1 - Branched alkylamino thiazole derivatives process for their preparation and pharmaceutical compositions containing them - Google Patents
Branched alkylamino thiazole derivatives process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HK1002632A1 HK1002632A1 HK98101081A HK98101081A HK1002632A1 HK 1002632 A1 HK1002632 A1 HK 1002632A1 HK 98101081 A HK98101081 A HK 98101081A HK 98101081 A HK98101081 A HK 98101081A HK 1002632 A1 HK1002632 A1 HK 1002632A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- radical
- cycloalkyl
- alkyl
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR929207736A FR2692893B1 (fr) | 1992-06-24 | 1992-06-24 | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1002632A1 true HK1002632A1 (en) | 1998-09-04 |
Family
ID=9431129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98101081A HK1002632A1 (en) | 1992-06-24 | 1998-02-12 | Branched alkylamino thiazole derivatives process for their preparation and pharmaceutical compositions containing them |
Country Status (30)
Country | Link |
---|---|
US (1) | US5464847A (ko) |
EP (1) | EP0576350B1 (ko) |
JP (1) | JPH0656809A (ko) |
KR (1) | KR100228813B1 (ko) |
CN (1) | CN1035552C (ko) |
AT (1) | ATE159721T1 (ko) |
AU (1) | AU665256B2 (ko) |
BR (1) | BR9302643A (ko) |
CA (1) | CA2099062A1 (ko) |
CZ (1) | CZ125293A3 (ko) |
DE (1) | DE69314855T2 (ko) |
DK (1) | DK0576350T3 (ko) |
ES (1) | ES2110070T3 (ko) |
FI (1) | FI932909A (ko) |
FR (1) | FR2692893B1 (ko) |
GR (1) | GR3025684T3 (ko) |
HK (1) | HK1002632A1 (ko) |
HU (1) | HUT66384A (ko) |
IL (1) | IL106088A (ko) |
IS (1) | IS4040A (ko) |
MX (1) | MX9303770A (ko) |
MY (1) | MY109557A (ko) |
NO (1) | NO303118B1 (ko) |
NZ (1) | NZ247949A (ko) |
PH (1) | PH30921A (ko) |
PL (2) | PL174734B1 (ko) |
RU (1) | RU2102389C1 (ko) |
SG (1) | SG50626A1 (ko) |
SI (1) | SI9300337A (ko) |
TW (1) | TW256834B (ko) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2714059B1 (fr) * | 1993-12-21 | 1996-03-08 | Sanofi Elf | Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
DE4401912A1 (de) * | 1994-01-24 | 1995-07-27 | Basf Ag | Methinfarbstoffe in der nichtlinearen Optik |
US5646152A (en) * | 1994-06-15 | 1997-07-08 | Pfizer Inc. | Methods of administering CRF antagonists |
US5795905A (en) * | 1995-06-06 | 1998-08-18 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
FR2735777B1 (fr) * | 1995-06-21 | 1997-09-12 | Sanofi Sa | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
NZ320227A (en) | 1995-10-17 | 1998-11-25 | Janssen Pharmaceutica Nv | Amino substituted pyrimidines and triazines |
US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
US6124289A (en) * | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
US6060478A (en) * | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
US7094782B1 (en) | 1996-07-24 | 2006-08-22 | Bristol-Myers Squibb Company | Azolo triazines and pyrimidines |
US5861398A (en) * | 1996-08-26 | 1999-01-19 | Alanex Corporation | Benzoperimidine-carboxylic acids and derivatives thereof |
JP2001502300A (ja) | 1996-09-16 | 2001-02-20 | デュポン ファーマシューティカルズ カンパニー | ピラジノン類およびトリアジノン類およびその誘導体類 |
FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
EP0970082A2 (en) | 1997-02-18 | 2000-01-12 | Neurocrine Biosciences, Inc. | Biazacyclic crf antagonists |
ES2180338T3 (es) | 1998-11-12 | 2003-02-01 | Neurocrine Biosciences Inc | Antagonistas del receptor de crf y metodos relacionados. |
US6531475B1 (en) * | 1998-11-12 | 2003-03-11 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
US6348466B1 (en) | 1998-11-12 | 2002-02-19 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
FR2796380B3 (fr) | 1999-07-15 | 2001-08-17 | Sanofi Synthelabo | Nouveaux derives d'aminothiazoles, leur preparation et les compositions pharmaceutiques les contenant |
US6432989B1 (en) | 1999-08-27 | 2002-08-13 | Pfizer Inc | Use of CRF antagonists to treat circadian rhythm disorders |
EP1149583A3 (en) * | 2000-04-13 | 2001-11-14 | Pfizer Products Inc. | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues |
AU2002314744A1 (en) * | 2001-04-17 | 2002-10-28 | Sepracor, Inc. | Thiazole and other heterocyclic ligands and use thereof |
US7276526B2 (en) | 2001-07-13 | 2007-10-02 | Bristol-Myers Squibb Pharma Company | Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands |
WO2003015777A1 (en) * | 2001-08-13 | 2003-02-27 | Lion Bioscience Ag | Nr1h4 nuclear receptor binding compounds |
DE60131967D1 (de) * | 2001-08-13 | 2008-01-31 | Phenex Pharmaceuticals Ag | Nr1h4-kern-rezeptor-bindende verbindungen |
ES2434493T3 (es) * | 2002-03-14 | 2013-12-16 | Takeda Pharmaceutical Company Limited | Regulador del VDAC |
JP4484439B2 (ja) * | 2002-03-14 | 2010-06-16 | 国立大学法人東京工業大学 | Vdac調節剤 |
CN1902196B (zh) * | 2003-12-26 | 2010-12-29 | 协和发酵麒麟株式会社 | 噻唑衍生物 |
EP1981507A4 (en) * | 2006-02-01 | 2011-10-19 | Merck Sharp & Dohme | INHIBITORS OF THE POTASSIUM CANAL |
CN101528710B (zh) * | 2006-10-19 | 2012-11-07 | 弗·哈夫曼-拉罗切有限公司 | 氨基甲基-4-咪唑类 |
JP5467735B2 (ja) * | 2007-07-02 | 2014-04-09 | 東ソー株式会社 | 円筒形スパッタリングターゲット |
WO2015112642A1 (en) | 2014-01-21 | 2015-07-30 | Neurocrine Biosciences, Inc. | Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4264134A (en) * | 1978-05-26 | 1981-04-28 | Elliott Brothers (London) Limited | Display arrangements |
DK150068C (da) * | 1978-06-02 | 1987-06-29 | Pfizer | Analogifremgangsmaade til fremstilling af aminothiazoler |
FR2612187B1 (fr) * | 1987-03-12 | 1989-07-21 | Sanofi Sa | Derives du thiazole actifs sur le systeme cholinergique, leur procede de preparation et compositions pharmaceutiques en contenant |
US5232921A (en) * | 1987-03-12 | 1993-08-03 | Sanofi | Thiazole derivatives active on the cholinergic system, process for obtention and pharmaceutical compositions |
FR2656610B1 (fr) * | 1989-12-29 | 1992-05-07 | Sanofi Sa | Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique. |
-
1992
- 1992-06-24 FR FR929207736A patent/FR2692893B1/fr not_active Expired - Fee Related
-
1993
- 1993-06-21 IL IL106088A patent/IL106088A/xx not_active IP Right Cessation
- 1993-06-22 PH PH46390A patent/PH30921A/en unknown
- 1993-06-22 AT AT93401603T patent/ATE159721T1/de not_active IP Right Cessation
- 1993-06-22 AU AU41399/93A patent/AU665256B2/en not_active Ceased
- 1993-06-22 EP EP93401603A patent/EP0576350B1/fr not_active Expired - Lifetime
- 1993-06-22 NZ NZ247949A patent/NZ247949A/en unknown
- 1993-06-22 ES ES93401603T patent/ES2110070T3/es not_active Expired - Lifetime
- 1993-06-22 DK DK93401603T patent/DK0576350T3/da active
- 1993-06-22 DE DE69314855T patent/DE69314855T2/de not_active Expired - Fee Related
- 1993-06-22 SG SG1996007157A patent/SG50626A1/en unknown
- 1993-06-23 CN CN93109438A patent/CN1035552C/zh not_active Expired - Fee Related
- 1993-06-23 RU RU93044129A patent/RU2102389C1/ru active
- 1993-06-23 US US08/080,172 patent/US5464847A/en not_active Expired - Fee Related
- 1993-06-23 NO NO932319A patent/NO303118B1/no not_active IP Right Cessation
- 1993-06-23 PL PL93299445A patent/PL174734B1/pl unknown
- 1993-06-23 CZ CZ931252A patent/CZ125293A3/cs unknown
- 1993-06-23 PL PL93321372A patent/PL176103B1/pl unknown
- 1993-06-23 JP JP5152479A patent/JPH0656809A/ja active Pending
- 1993-06-23 HU HU9301850A patent/HUT66384A/hu unknown
- 1993-06-23 CA CA002099062A patent/CA2099062A1/en not_active Abandoned
- 1993-06-23 FI FI932909A patent/FI932909A/fi unknown
- 1993-06-23 MY MYPI93001219A patent/MY109557A/en unknown
- 1993-06-23 IS IS4040A patent/IS4040A/is unknown
- 1993-06-23 SI SI9300337A patent/SI9300337A/sl unknown
- 1993-06-23 MX MX9303770A patent/MX9303770A/es not_active IP Right Cessation
- 1993-06-24 BR BR9302643A patent/BR9302643A/pt not_active Application Discontinuation
- 1993-06-24 KR KR1019930011709A patent/KR100228813B1/ko not_active IP Right Cessation
- 1993-08-31 TW TW082107085A patent/TW256834B/zh not_active IP Right Cessation
-
1997
- 1997-12-16 GR GR970403334T patent/GR3025684T3/el unknown
-
1998
- 1998-02-12 HK HK98101081A patent/HK1002632A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |