GT200800206A - Dimeros de derivados de artemisinina, su preparacion y su aplicacion en terapeutica - Google Patents
Dimeros de derivados de artemisinina, su preparacion y su aplicacion en terapeuticaInfo
- Publication number
- GT200800206A GT200800206A GT200800206A GT200800206A GT200800206A GT 200800206 A GT200800206 A GT 200800206A GT 200800206 A GT200800206 A GT 200800206A GT 200800206 A GT200800206 A GT 200800206A GT 200800206 A GT200800206 A GT 200800206A
- Authority
- GT
- Guatemala
- Prior art keywords
- dimeros
- therapeutics
- preparation
- application
- artemisinine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/04—Seven-membered rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/04—Seven-membered rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
- C07D323/04—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
Abstract
LA PRESENTE INVENCION SE REFIERE A DIMEROS DE DERIVADOS DE LA ARTEMISININA QUE PRESENTAN UNA ACTIVIDAD ANTICANCERIGENA Y EN PARTICULAR UNA ACTIVIDAD INHIBIDORA DE LA PROLIFERACION CELULAR EN LA QUE HASTA AHORA LA MAYORIA DE LOS COMPUESTOS COMERCIALES UTILIZADOS EN QUIMIOTERAPIA PLANTEAN PROBLEMAS IMPORTANTES DE EFECTOS SECUNDARIOS, DE TOLERANCIA POR LOS PACIENTES O TAMBIEN DE RESISTENCIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0603209A FR2899586B1 (fr) | 2006-04-11 | 2006-04-11 | Dimeres de derives d'artemisinine, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200800206A true GT200800206A (es) | 2008-12-04 |
Family
ID=37429238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200800206A GT200800206A (es) | 2006-04-11 | 2008-10-08 | Dimeros de derivados de artemisinina, su preparacion y su aplicacion en terapeutica |
Country Status (40)
Country | Link |
---|---|
US (1) | US8314142B2 (es) |
EP (1) | EP2007769B1 (es) |
JP (1) | JP5265518B2 (es) |
KR (1) | KR101357523B1 (es) |
CN (1) | CN101421276B (es) |
AR (1) | AR060400A1 (es) |
AT (1) | ATE512970T1 (es) |
AU (1) | AU2007235813B2 (es) |
BR (1) | BRPI0710152A2 (es) |
CA (1) | CA2641138C (es) |
CR (1) | CR10247A (es) |
CY (1) | CY1111833T1 (es) |
DK (1) | DK2007769T3 (es) |
EA (1) | EA015607B1 (es) |
EC (1) | ECSP088792A (es) |
ES (1) | ES2367715T3 (es) |
FR (1) | FR2899586B1 (es) |
GT (1) | GT200800206A (es) |
HK (1) | HK1131779A1 (es) |
HN (1) | HN2008001521A (es) |
HR (1) | HRP20110654T1 (es) |
IL (1) | IL194655A0 (es) |
JO (1) | JO2721B1 (es) |
MA (1) | MA30410B1 (es) |
ME (1) | ME00094B (es) |
MX (1) | MX2008012732A (es) |
MY (1) | MY154970A (es) |
NO (1) | NO20084352L (es) |
NZ (1) | NZ571342A (es) |
PE (1) | PE20080055A1 (es) |
PL (1) | PL2007769T3 (es) |
PT (1) | PT2007769E (es) |
RS (1) | RS51952B (es) |
SI (1) | SI2007769T1 (es) |
TN (1) | TNSN08321A1 (es) |
TW (1) | TWI423979B (es) |
UA (1) | UA94744C2 (es) |
UY (1) | UY30276A1 (es) |
WO (1) | WO2007116135A1 (es) |
ZA (1) | ZA200808025B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2925495B1 (fr) * | 2007-12-21 | 2010-09-10 | Pf Medicament | Derives dimeriques d'artemisinine et application en therapie anticancereuse |
FR2934593B1 (fr) * | 2008-07-29 | 2010-09-10 | Pf Medicament | Derives dimeriques d'artemisinine et application en therapie anticancereuse |
WO2011071981A2 (en) * | 2009-12-08 | 2011-06-16 | The Johns Hopkins University | Anti-cytomegalovirus activity of artemisinin-derived dimers |
US8815942B2 (en) | 2010-10-20 | 2014-08-26 | The Royal Institution For The Advancement Of Learning/Mcgill University | Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease |
CN102010422B (zh) * | 2010-11-23 | 2014-11-26 | 沈阳药科大学 | 含有胍基的青蒿素类衍生物及其应用 |
CN102614168A (zh) * | 2011-01-31 | 2012-08-01 | 上海交通大学医学院附属瑞金医院 | 一种青蒿素衍生物及其药用盐的应用 |
WO2012111025A2 (en) * | 2011-02-14 | 2012-08-23 | Council Of Scientific & Industrial Research | 1,2,3-triazole containing artemisinin compounds and process for preparation thereof |
CN103570738B (zh) * | 2012-08-07 | 2016-04-13 | 中国科学院上海生命科学研究院 | 新型青蒿素衍生物及其制法和应用 |
CN106928274B (zh) * | 2017-02-28 | 2019-09-10 | 东南大学 | 一种双氢青蒿素二倍体衍生物、其药物组合物及应用 |
CN110240605B (zh) * | 2018-03-08 | 2021-12-31 | 中国科学院上海药物研究所 | 青蒿素二聚物的制备方法 |
CN109467565B (zh) * | 2018-08-16 | 2020-07-10 | 云白药征武科技(上海)有限公司 | 双氢青蒿素三聚体及其制备方法和应用 |
EP3911311A4 (en) * | 2019-02-26 | 2023-01-25 | Mahmoud A. Elsohly | SELECTED ARTEMISININ DIMERS FOR THE TREATMENT OF LEISHMANIA |
CN117285548A (zh) * | 2022-06-16 | 2023-12-26 | 云南苏理生物医药科技有限公司 | 一种含硫类青蒿素二聚体、其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1084333C (zh) | 1998-06-17 | 2002-05-08 | 中国科学院上海药物研究所 | 新的青蒿素化合物,其制备方法以及含有它们的药物组合物 |
FR2831538B1 (fr) * | 2001-10-26 | 2004-01-16 | Centre Nat Rech Scient | Nouveaux derives de l'artemisinine, et leurs utilisations dans le traitement du paludisme |
US6790863B2 (en) * | 2002-10-15 | 2004-09-14 | University Of Mississippi | Dihydroartemisinin and dihydroartemisitene dimers as anti-cancer and anti-infective agents |
US7842720B2 (en) * | 2004-06-21 | 2010-11-30 | Elsohly Laboratories, Incorporated | Anticancer and antiprotozoal dihydroartemisinene and dihydroartemisitene dimers with desirable chemical functionalities |
CN101125142A (zh) | 2007-07-24 | 2008-02-20 | 北京中医药大学东直门医院 | 青蒿素在制备抗肿瘤多药耐药药物中的应用 |
-
2006
- 2006-04-11 FR FR0603209A patent/FR2899586B1/fr not_active Expired - Fee Related
-
2007
- 2007-04-06 WO PCT/FR2007/000585 patent/WO2007116135A1/fr active Application Filing
- 2007-04-06 MY MYPI20084058A patent/MY154970A/en unknown
- 2007-04-06 DK DK07731259.3T patent/DK2007769T3/da active
- 2007-04-06 JP JP2009504774A patent/JP5265518B2/ja not_active Expired - Fee Related
- 2007-04-06 SI SI200730713T patent/SI2007769T1/sl unknown
- 2007-04-06 RS RS20110399A patent/RS51952B/en unknown
- 2007-04-06 PL PL07731259T patent/PL2007769T3/pl unknown
- 2007-04-06 ES ES07731259T patent/ES2367715T3/es active Active
- 2007-04-06 UA UAA200813044A patent/UA94744C2/ru unknown
- 2007-04-06 MX MX2008012732A patent/MX2008012732A/es active IP Right Grant
- 2007-04-06 AT AT07731259T patent/ATE512970T1/de active
- 2007-04-06 CA CA2641138A patent/CA2641138C/fr not_active Expired - Fee Related
- 2007-04-06 KR KR1020087024812A patent/KR101357523B1/ko not_active IP Right Cessation
- 2007-04-06 ZA ZA200808025A patent/ZA200808025B/xx unknown
- 2007-04-06 EA EA200870421A patent/EA015607B1/ru not_active IP Right Cessation
- 2007-04-06 CN CN200780013054XA patent/CN101421276B/zh not_active Expired - Fee Related
- 2007-04-06 ME MEP-2008-123A patent/ME00094B/me unknown
- 2007-04-06 BR BRPI0710152-0A patent/BRPI0710152A2/pt not_active IP Right Cessation
- 2007-04-06 PT PT07731259T patent/PT2007769E/pt unknown
- 2007-04-06 NZ NZ571342A patent/NZ571342A/en not_active IP Right Cessation
- 2007-04-06 EP EP07731259A patent/EP2007769B1/fr active Active
- 2007-04-06 AU AU2007235813A patent/AU2007235813B2/en not_active Ceased
- 2007-04-09 PE PE2007000422A patent/PE20080055A1/es not_active Application Discontinuation
- 2007-04-10 AR ARP070101497A patent/AR060400A1/es not_active Application Discontinuation
- 2007-04-10 TW TW096112535A patent/TWI423979B/zh not_active IP Right Cessation
- 2007-04-11 UY UY30276A patent/UY30276A1/es not_active Application Discontinuation
- 2007-04-11 JO JO2007131A patent/JO2721B1/en active
-
2008
- 2008-08-07 TN TNP2008000321A patent/TNSN08321A1/en unknown
- 2008-08-26 CR CR10247A patent/CR10247A/es unknown
- 2008-10-02 US US12/244,225 patent/US8314142B2/en not_active Expired - Fee Related
- 2008-10-03 HN HN2008001521A patent/HN2008001521A/es unknown
- 2008-10-06 EC EC2008008792A patent/ECSP088792A/es unknown
- 2008-10-07 IL IL194655A patent/IL194655A0/en unknown
- 2008-10-08 GT GT200800206A patent/GT200800206A/es unknown
- 2008-10-16 NO NO20084352A patent/NO20084352L/no not_active Application Discontinuation
- 2008-11-10 MA MA31376A patent/MA30410B1/fr unknown
-
2009
- 2009-10-21 HK HK09109745.0A patent/HK1131779A1/xx not_active IP Right Cessation
-
2011
- 2011-09-13 HR HR20110654T patent/HRP20110654T1/hr unknown
- 2011-09-15 CY CY20111100886T patent/CY1111833T1/el unknown
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