BRPI0808172A2 - Compostos heterocíclicos, composições compreendendo-os e métodos de seu uso. - Google Patents
Compostos heterocíclicos, composições compreendendo-os e métodos de seu uso.Info
- Publication number
- BRPI0808172A2 BRPI0808172A2 BRPI0808172-7A2A BRPI0808172A BRPI0808172A2 BR PI0808172 A2 BRPI0808172 A2 BR PI0808172A2 BR PI0808172 A BRPI0808172 A BR PI0808172A BR PI0808172 A2 BRPI0808172 A2 BR PI0808172A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- understanding
- methods
- heterocyclic compounds
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90435707P | 2007-03-01 | 2007-03-01 | |
| PCT/US2008/055210 WO2008109314A1 (en) | 2007-03-01 | 2008-02-28 | Heterocyclic compounds, compositions comprising them and methods of their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0808172A2 true BRPI0808172A2 (pt) | 2014-11-04 |
Family
ID=39577881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0808172-7A2A BRPI0808172A2 (pt) | 2007-03-01 | 2008-02-28 | Compostos heterocíclicos, composições compreendendo-os e métodos de seu uso. |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US7598280B2 (pt) |
| EP (1) | EP2125788B9 (pt) |
| JP (1) | JP5610772B2 (pt) |
| KR (1) | KR20090117763A (pt) |
| AR (1) | AR065509A1 (pt) |
| AT (1) | ATE504585T1 (pt) |
| AU (1) | AU2008223210B2 (pt) |
| BR (1) | BRPI0808172A2 (pt) |
| CA (1) | CA2679101C (pt) |
| CO (1) | CO6220950A2 (pt) |
| DE (1) | DE602008006045D1 (pt) |
| DK (1) | DK2125788T3 (pt) |
| EA (1) | EA016495B1 (pt) |
| EC (1) | ECSP099675A (pt) |
| ES (1) | ES2364116T3 (pt) |
| IL (1) | IL200387A (pt) |
| MX (1) | MX2009009190A (pt) |
| NZ (1) | NZ578974A (pt) |
| PL (1) | PL2125788T3 (pt) |
| PT (1) | PT2125788E (pt) |
| TW (1) | TW200848029A (pt) |
| WO (1) | WO2008109314A1 (pt) |
| ZA (1) | ZA200905671B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
| TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
| TW201002698A (en) * | 2008-06-18 | 2010-01-16 | Lexicon Pharmaceuticals Inc | Methods of preparing imidazole-based bicyclic compounds |
| AU2009271408A1 (en) * | 2008-06-18 | 2010-01-21 | Lexicon Pharmaceuticals, Inc. | Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl) -1H-imidazol-4-yl)butane-1,2,3,4-tetraol and methods of their use |
| WO2010022217A1 (en) * | 2008-08-22 | 2010-02-25 | Lexicon Pharmaceuticals, Inc. | Combinations comprising bicyclic s1p lyase inhibitors |
| AR074061A1 (es) * | 2008-10-31 | 2010-12-22 | Lexicon Pharmaceuticals Inc | Inhibidores de s1p liasa para el tratamiento de la malaria cerebral y formulacion farmaceutica |
| TW201132630A (en) | 2010-02-18 | 2011-10-01 | Daiichi Sankyo Co Ltd | Imidazole derivatives |
| WO2012002274A1 (ja) | 2010-06-28 | 2012-01-05 | 第一三共株式会社 | 培養細胞を用いたｓ１ｐリアーゼ阻害剤のスクリーニング方法 |
| WO2012097330A2 (en) * | 2011-01-14 | 2012-07-19 | University Of Washington | Compositions and methods for treating degenerative muscle conditions |
| US9120835B2 (en) | 2011-06-28 | 2015-09-01 | Daiichi Sankyo Company Limited | Phosphoric acid ester derivatives |
| WO2013049272A2 (en) | 2011-09-29 | 2013-04-04 | Theraceutix, Llc | Composition and method for treatment of symptoms associated with various skin conditions |
| US20230121797A1 (en) * | 2020-03-27 | 2023-04-20 | Ac Bioscience Sa | A combination of flavonoids and sphingosine 1 phosphate lyase inhibitors for the treatment of lung inflammation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567194A (en) | 1983-03-10 | 1986-01-28 | The Coca-Cola Company | 2-Acylimidazole compounds, their synthesis and use as medicinal agents |
| ZA974811B (en) * | 1996-05-31 | 1997-12-30 | Univ Wollongong | Novel therapeutic compounds. |
| US6423527B1 (en) | 1997-09-29 | 2002-07-23 | Children's Hospital Medical Center Of Northern California | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor |
| CN1834095B (zh) * | 2005-03-18 | 2011-04-20 | 中国科学院上海药物研究所 | 一类非核苷类抗病毒抑制剂及其制备方法和用途 |
| CA2612592A1 (en) * | 2005-06-28 | 2007-01-04 | Merck & Co., Inc. | Non-nucleoside reverse transcriptase inhibitors |
| US7649098B2 (en) | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
| TWI412362B (zh) | 2007-04-12 | 2013-10-21 | Lexicon Pharmaceuticals Inc | （ｅ）-１-（４-（（１ｒ，２ｓ，３ｒ）-１，２，３，４-四羥丁基）-１ｈ-咪唑-２-基）乙酮肟的固體形式 |
-
2008
- 2008-02-27 TW TW097106871A patent/TW200848029A/zh unknown
- 2008-02-28 AT AT08730902T patent/ATE504585T1/de active
- 2008-02-28 DK DK08730902.7T patent/DK2125788T3/da active
- 2008-02-28 WO PCT/US2008/055210 patent/WO2008109314A1/en active Application Filing
- 2008-02-28 EA EA200970818A patent/EA016495B1/ru not_active IP Right Cessation
- 2008-02-28 PL PL08730902T patent/PL2125788T3/pl unknown
- 2008-02-28 PT PT08730902T patent/PT2125788E/pt unknown
- 2008-02-28 EP EP08730902A patent/EP2125788B9/en active Active
- 2008-02-28 MX MX2009009190A patent/MX2009009190A/es active IP Right Grant
- 2008-02-28 ES ES08730902T patent/ES2364116T3/es active Active
- 2008-02-28 AU AU2008223210A patent/AU2008223210B2/en active Active
- 2008-02-28 JP JP2009551836A patent/JP5610772B2/ja active Active
- 2008-02-28 AR ARP080100821A patent/AR065509A1/es unknown
- 2008-02-28 US US12/038,872 patent/US7598280B2/en active Active
- 2008-02-28 ZA ZA200905671A patent/ZA200905671B/xx unknown
- 2008-02-28 DE DE602008006045T patent/DE602008006045D1/de active Active
- 2008-02-28 BR BRPI0808172-7A2A patent/BRPI0808172A2/pt not_active Application Discontinuation
- 2008-02-28 CA CA2679101A patent/CA2679101C/en active Active
- 2008-02-28 NZ NZ578974A patent/NZ578974A/en unknown
- 2008-02-28 KR KR1020097018102A patent/KR20090117763A/ko not_active Application Discontinuation
-
2009
- 2009-08-13 IL IL200387A patent/IL200387A/en active IP Right Grant
- 2009-08-24 US US12/545,954 patent/US7825142B2/en active Active
- 2009-09-30 CO CO09107325A patent/CO6220950A2/es not_active Application Discontinuation
- 2009-10-02 EC EC2009009675A patent/ECSP099675A/es unknown
-
2010
- 2010-10-13 US US12/903,657 patent/US20110082178A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5610772B2 (ja) | 2014-10-22 |
| KR20090117763A (ko) | 2009-11-12 |
| WO2008109314A1 (en) | 2008-09-12 |
| IL200387A0 (en) | 2010-04-29 |
| AU2008223210B2 (en) | 2013-08-22 |
| US7825142B2 (en) | 2010-11-02 |
| US20110082178A1 (en) | 2011-04-07 |
| CA2679101A1 (en) | 2008-09-12 |
| EP2125788A1 (en) | 2009-12-02 |
| CO6220950A2 (es) | 2010-11-19 |
| EP2125788B1 (en) | 2011-04-06 |
| PL2125788T3 (pl) | 2011-09-30 |
| PT2125788E (pt) | 2011-07-05 |
| DE602008006045D1 (de) | 2011-05-19 |
| TW200848029A (en) | 2008-12-16 |
| IL200387A (en) | 2013-10-31 |
| JP2010520214A (ja) | 2010-06-10 |
| NZ578974A (en) | 2011-11-25 |
| DK2125788T3 (da) | 2011-07-11 |
| EA200970818A1 (ru) | 2010-02-26 |
| ECSP099675A (es) | 2009-11-30 |
| AU2008223210A1 (en) | 2008-09-12 |
| ATE504585T1 (de) | 2011-04-15 |
| MX2009009190A (es) | 2009-09-04 |
| EA016495B1 (ru) | 2012-05-30 |
| US7598280B2 (en) | 2009-10-06 |
| US20090030050A1 (en) | 2009-01-29 |
| CA2679101C (en) | 2015-11-24 |
| EP2125788B9 (en) | 2011-07-20 |
| ZA200905671B (en) | 2010-10-27 |
| ES2364116T3 (es) | 2011-08-25 |
| AR065509A1 (es) | 2009-06-10 |
| US20090312375A1 (en) | 2009-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |