GR980300016T1 - Dna encoding galanin galr2 receptors and uses thereof - Google Patents
Dna encoding galanin galr2 receptors and uses thereofInfo
- Publication number
- GR980300016T1 GR980300016T1 GR980300016T GR980300016T GR980300016T1 GR 980300016 T1 GR980300016 T1 GR 980300016T1 GR 980300016 T GR980300016 T GR 980300016T GR 980300016 T GR980300016 T GR 980300016T GR 980300016 T1 GR980300016 T1 GR 980300016T1
- Authority
- GR
- Greece
- Prior art keywords
- dna encoding
- galr2 receptors
- encoding galanin
- galanin galr2
- receptors
- Prior art date
Links
- 102000019432 Galanin Human genes 0.000 title 1
- 101800002068 Galanin Proteins 0.000 title 1
- SLZIZIJTGAYEKK-CIJSCKBQSA-N molport-023-220-247 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)CN)[C@@H](C)O)C1=CNC=N1 SLZIZIJTGAYEKK-CIJSCKBQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59049496A | 1996-01-24 | 1996-01-24 | |
US62604696A | 1996-04-01 | 1996-04-01 | |
US08/626,685 US5972624A (en) | 1996-01-24 | 1996-04-01 | Method of identifying ligands which bind recombinant galanin receptor (GALR2) |
US72183796A | 1996-09-27 | 1996-09-27 | |
PCT/US1997/001301 WO1997026853A2 (en) | 1996-01-24 | 1997-01-24 | Dna encoding galanin galr2 receptors and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GR980300016T1 true GR980300016T1 (en) | 1998-03-31 |
Family
ID=27505000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980300016T GR980300016T1 (en) | 1996-01-24 | 1998-03-31 | Dna encoding galanin galr2 receptors and uses thereof |
Country Status (9)
Country | Link |
---|---|
US (4) | US6790656B1 (el) |
EP (1) | EP0819167A4 (el) |
JP (1) | JP2000504107A (el) |
AU (1) | AU730137B2 (el) |
CA (1) | CA2216227A1 (el) |
DE (1) | DE819167T1 (el) |
ES (1) | ES2112238T1 (el) |
GR (1) | GR980300016T1 (el) |
WO (1) | WO1997026853A2 (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU730137B2 (en) | 1996-01-24 | 2001-03-01 | H. Lundbeck A/S | DNA encoding galanin GALR2 receptors and uses thereof |
US6410686B1 (en) | 1996-06-05 | 2002-06-25 | Bayer Corporation | Galanin receptor 2 protein |
SE9602822D0 (sv) | 1996-07-19 | 1996-07-19 | Astra Pharma Inc | New receptor |
EP0918455B1 (en) * | 1996-07-24 | 2003-04-16 | Neurotargets Limited | Use of galanin to repair nerve damage |
EP0948532A4 (en) | 1996-12-27 | 2002-09-25 | Merck & Co Inc | GALANIN GALR2 RECEPTOR FROM THE MOUSE AND NUCLEOTIDES THAT ENCODE IT |
WO1999031130A1 (en) | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Galanin receptor galr3 and nucleotides encoding same |
US6337206B1 (en) | 1997-12-18 | 2002-01-08 | Merck & Co., Inc. | Nucleic acid encoding mouse galanin receptor (GALR2) |
US6232066B1 (en) * | 1997-12-19 | 2001-05-15 | Neogen, Inc. | High throughput assay system |
AU2003264177A1 (en) * | 2002-09-25 | 2004-04-19 | Garvan Institute Of Medical Research | Method for inducing mammary epithelial cell differentiation |
GB0403509D0 (en) * | 2004-02-17 | 2004-03-24 | Neuro Targets Ltd | Galanin receptors and brain injury |
US7309589B2 (en) * | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
JP2008528951A (ja) * | 2005-01-03 | 2008-07-31 | ザ スクリプス リサーチ インスティテュート | 抗うつ薬の標的 |
WO2009046859A2 (en) * | 2007-09-11 | 2009-04-16 | Mondobiotech Laboratories Ag | Use of af12198 and dago as therapeutic agents |
US20100204129A1 (en) * | 2008-09-09 | 2010-08-12 | Dorian Bevec | Use of a peptide as a therapeutic agent |
AU2009301457B2 (en) * | 2008-10-09 | 2015-08-13 | Merck Patent Gmbh | Estrogen and anti-estrogen marker genes |
CN113512592A (zh) * | 2021-04-23 | 2021-10-19 | 中国科学院深圳先进技术研究院 | 用于检测甘丙肽分泌细胞的引物、探针以及试剂盒 |
WO2024116101A1 (en) * | 2022-11-29 | 2024-06-06 | Neuracle Science Co., Ltd. | Use of galr2 agonists to treat gastrointestinal and/or endocrine disorders |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5436455A (en) * | 1990-06-27 | 1995-07-25 | Futrex Inc. | Non-invasive near-infrared quantitative measurement instrument |
US5462856A (en) | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
JPH06510363A (ja) | 1990-10-29 | 1994-11-17 | ディカルブ プラント ジェネティクス | 磁気性粒子を使用する生物学的材料の単離 |
WO1992012997A1 (en) | 1991-01-16 | 1992-08-06 | The General Hospital Corporation | Human galanin |
AU1462692A (en) * | 1991-02-25 | 1992-09-15 | Board Of Regents Of The University Of Washington, The | Methods for detecting galanin antagonists |
JP3135262B2 (ja) | 1991-03-06 | 2001-02-13 | ガーヴァン インスティチュート オブ メディカル リサーチ | ヒトのガラニン、ヒトのガラニンをエンコードするcD NAクローンとヒトのガラニン製造方法 |
SE9101472D0 (sv) | 1991-05-15 | 1991-05-15 | Trion Forskning & Utveckling | Galanin antagonist |
US5576296A (en) * | 1991-05-15 | 1996-11-19 | Aktiebolaget Astra | Galanin antagonist |
US5436155A (en) | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
US5290808A (en) | 1992-11-06 | 1994-03-01 | Carter-Wallace, Inc. | Method to control the intake of food |
FR2716205B1 (fr) * | 1994-02-17 | 1996-04-12 | Rhone Poulenc Rorer Sa | Récepteur galanine, acides nucléiques, cellules transformées et utilisations. |
EP0711830A3 (en) | 1994-10-13 | 1997-06-11 | Takeda Chemical Industries Ltd | Murine and human galanin receptor |
US6562862B1 (en) | 1994-10-20 | 2003-05-13 | Eli Lilly And Company | Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y |
AU730137B2 (en) | 1996-01-24 | 2001-03-01 | H. Lundbeck A/S | DNA encoding galanin GALR2 receptors and uses thereof |
US5972624A (en) * | 1996-01-24 | 1999-10-26 | Synaptic Pharmaceutical Corporation | Method of identifying ligands which bind recombinant galanin receptor (GALR2) |
US6410686B1 (en) | 1996-06-05 | 2002-06-25 | Bayer Corporation | Galanin receptor 2 protein |
SE9602822D0 (sv) | 1996-07-19 | 1996-07-19 | Astra Pharma Inc | New receptor |
EP0918455B1 (en) | 1996-07-24 | 2003-04-16 | Neurotargets Limited | Use of galanin to repair nerve damage |
EP0948532A4 (en) * | 1996-12-27 | 2002-09-25 | Merck & Co Inc | GALANIN GALR2 RECEPTOR FROM THE MOUSE AND NUCLEOTIDES THAT ENCODE IT |
-
1997
- 1997-01-24 AU AU18427/97A patent/AU730137B2/en not_active Ceased
- 1997-01-24 WO PCT/US1997/001301 patent/WO1997026853A2/en not_active Application Discontinuation
- 1997-01-24 CA CA002216227A patent/CA2216227A1/en not_active Abandoned
- 1997-01-24 EP EP97904008A patent/EP0819167A4/en not_active Withdrawn
- 1997-01-24 DE DE0819167T patent/DE819167T1/de active Pending
- 1997-01-24 ES ES97904008T patent/ES2112238T1/es active Pending
- 1997-01-24 US US09/011,553 patent/US6790656B1/en not_active Expired - Fee Related
- 1997-01-24 JP JP9527082A patent/JP2000504107A/ja not_active Withdrawn
- 1997-07-23 US US08/899,112 patent/US6586191B2/en not_active Expired - Fee Related
-
1998
- 1998-03-31 GR GR980300016T patent/GR980300016T1/el unknown
-
2002
- 2002-10-31 US US10/285,019 patent/US7132248B2/en not_active Expired - Fee Related
- 2002-11-18 US US10/298,992 patent/US7060449B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7132248B2 (en) | 2006-11-07 |
AU1842797A (en) | 1997-08-20 |
EP0819167A2 (en) | 1998-01-21 |
DE819167T1 (de) | 1998-04-09 |
JP2000504107A (ja) | 2000-04-04 |
WO1997026853A2 (en) | 1997-07-31 |
EP0819167A4 (en) | 2002-06-12 |
US20030215823A1 (en) | 2003-11-20 |
CA2216227A1 (en) | 1997-07-31 |
ES2112238T1 (es) | 1998-04-01 |
US6790656B1 (en) | 2004-09-14 |
US7060449B2 (en) | 2006-06-13 |
US20030129702A1 (en) | 2003-07-10 |
US6586191B2 (en) | 2003-07-01 |
US20030082672A1 (en) | 2003-05-01 |
AU730137B2 (en) | 2001-03-01 |
WO1997026853A3 (en) | 1997-10-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0956291A4 (en) | DNA ENCODING GALANIN GALR3 RECEPTORS AND USES THEREOF | |
GR980300016T1 (en) | Dna encoding galanin galr2 receptors and uses thereof | |
IL130082A0 (en) | Dna encoding lepidopteran-active delta-endotoxins and its use | |
HUP0004484A3 (en) | Desaturase genes and their use | |
HUP0003201A3 (en) | Multiphase aggregate comprising carbon and its preparation | |
HK1040414A1 (en) | Elongase genes and uses thereof | |
HUP0001400A3 (en) | Osteoprotegerin binding proteins and receptors | |
ZA983189B (en) | Osteoprotegerin binding proteins and receptors | |
EP0960125A4 (en) | GALANIN GalR2 RECEPTOR AND NUCLEOTIDES ENCODING THE SAME | |
HUP0102302A3 (en) | Gene coding for heliomicine and use thereof | |
IL136696A0 (en) | Sigirr dna and polypeptides | |
IL132465A0 (en) | Characterising dna | |
AP2001002189A0 (en) | Genes and proteins and their uses | |
HUP9700676A3 (en) | Anti-fas recombinante antibodies and dna coding thereof | |
EP1147136A4 (en) | DNA CODED FOR A MAMMAL RECEPTOR (fb41a) AND THEIR USE | |
AU3378497A (en) | Galanin receptor galr2 | |
EP1242453A4 (en) | DNA CODING FOR SNORF62 AND SNORF72 RECEPTORS | |
EP1037913A4 (en) | GALANINE RECEPTOR GALR3 AND NUCLEOTIDES CODING THEM | |
EP0922052A4 (en) | RAT OBESITY RECEPTORS AND NUCLEOTIDES ENCODING THESE RECEPTORS | |
IL137493A0 (en) | Svph3-13 and spvh3-17 dna and polypeptides | |
IL136695A0 (en) | V201 dna and polypeptides | |
EP1181316A4 (en) | SNORF 36a AND SNORF 36b RECEPTORS ENCODING DNA | |
GB9824357D0 (en) | Protein and DNA coding therefor | |
IL136693A0 (en) | V196 dna and polypeptides | |
GB9623869D0 (en) | Galanin |