GR930100040A - Βελτιωμένη οξειδωτική προσ?ήκη συζεύξεως δια σπεκτροφωτομετρική ανάλυση αναλυτών (χημικών και βιοχημικών συστατικών). - Google Patents
Βελτιωμένη οξειδωτική προσ?ήκη συζεύξεως δια σπεκτροφωτομετρική ανάλυση αναλυτών (χημικών και βιοχημικών συστατικών).Info
- Publication number
- GR930100040A GR930100040A GR930100040A GR930100040A GR930100040A GR 930100040 A GR930100040 A GR 930100040A GR 930100040 A GR930100040 A GR 930100040A GR 930100040 A GR930100040 A GR 930100040A GR 930100040 A GR930100040 A GR 930100040A
- Authority
- GR
- Greece
- Prior art keywords
- dye
- mtbh
- ans
- produce
- oxidizing agent
- Prior art date
Links
- 238000005691 oxidative coupling reaction Methods 0.000 title abstract 2
- 238000004445 quantitative analysis Methods 0.000 title 1
- 239000000975 dye Substances 0.000 abstract 4
- PHOLIFLKGONSGY-CSKARUKUSA-N (e)-(3-methyl-1,3-benzothiazol-2-ylidene)hydrazine Chemical compound C1=CC=C2S\C(=N\N)N(C)C2=C1 PHOLIFLKGONSGY-CSKARUKUSA-N 0.000 abstract 3
- FWEOQOXTVHGIFQ-UHFFFAOYSA-M 8-anilinonaphthalene-1-sulfonate Chemical compound C=12C(S(=O)(=O)[O-])=CC=CC2=CC=CC=1NC1=CC=CC=C1 FWEOQOXTVHGIFQ-UHFFFAOYSA-M 0.000 abstract 3
- 239000007800 oxidant agent Substances 0.000 abstract 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 102000004316 Oxidoreductases Human genes 0.000 abstract 1
- 108090000854 Oxidoreductases Proteins 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000001045 blue dye Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
- 239000000049 pigment Substances 0.000 abstract 1
- 230000003595 spectral effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
- C12Q2326/32—3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate, i.e. MBTH
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Emergency Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
Μία συνεζευγμένη χρωστική, περιέχει 3-μεθυλ-2-βενζοθειαζολινονο υδραζόνη (ΜΤΒΗ) και 8-ανιλινο-1-ναφθαλινοσουλφονική ένωση (ANS), χρησιμοποιείται ως δείκτης σε μίασειρά αντιδράσεων που παράγουν ένα ισχυρό οξειδωτικόπαράγοντα όπως υπεροξείδιο του υδρογόνου ή άλλα υπεροξείδια ήυπερβορικές ενώσεις. Ο ισχυρός οξειδωτικός παράγων αντιδρά μετην συζυγική χρωστική δια να παραγάγει μία μπλέ χρωστικήένωση. Η συζυγιακή χρωστική ΜΤΒΗ-ANS παρουσιάζει ισχυρά καιεπίπεδο φασματική απορρόφηση στην περιοχή περίπου 600 έως 650νανομέτρα. Την περιοχή αυτή δεν την επηρεάζουν οι χρωστικέςτου αίματος και έτσι καθίσταται δυνατή μία μέτρηση τηςγλυκόζης και άλλων αναλυτών που αντιδρούν με το ένζυμοοξειδάσης προς παραγωγή του ισχυρού οξειδωτικού παράγοντοςδια χρησιμοποιήσεως οπτικών LTD επακριβώς άνευ πολλής οπτικήςκλιμακώσεως. Περαιτέρω τα ΜΤΒΗ και ANS είναι πολύ διαλυτά ειςτο υδατικό διάλυμα, αλλά καθίστανται αδιάλυτα μετά τηνοξειδωτική σύζευξη. Η μικρα διαλυτότης περιορίζει στοελάχιστον την εξασθένιση της χρωστικής και έτσι δίδει ένασταθερό τελικό σημείο.ω
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82965492A | 1992-02-03 | 1992-02-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
GR930100040A true GR930100040A (el) | 1993-10-29 |
GR1002975B GR1002975B (el) | 1998-09-23 |
Family
ID=25255147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR930100040A GR1002975B (el) | 1992-02-03 | 1993-02-04 | Βελτιωμενη οξειδωτικη προσθηκη συζευξεως δια σπεκτροφωτομετρικη αναλυση αναλυτων (χημικων και βιοχημικων συστατικων). |
Country Status (10)
Country | Link |
---|---|
US (1) | US5453360A (el) |
EP (1) | EP0555045B1 (el) |
JP (1) | JP3342077B2 (el) |
AT (1) | ATE159052T1 (el) |
AU (1) | AU659525B2 (el) |
CA (1) | CA2088652C (el) |
DE (1) | DE69314363T2 (el) |
DK (1) | DK0555045T3 (el) |
ES (1) | ES2109429T3 (el) |
GR (1) | GR1002975B (el) |
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US9386944B2 (en) | 2008-04-11 | 2016-07-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte detecting device |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
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CN102305852B (zh) * | 2011-05-17 | 2014-12-10 | 湖州麦迪诺华医疗科技有限公司 | 一种体外诊断医疗器材所用的染色剂 |
CA2950166C (en) | 2014-07-25 | 2023-08-01 | Becton, Dickinson And Company | Analyte test strip assays, and test strips and kits for use in practicing the same |
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US4089747A (en) * | 1976-08-09 | 1978-05-16 | Eastman Kodak Company | Compositions for the detection of hydrogen peroxide |
US4119405A (en) * | 1978-02-13 | 1978-10-10 | Miles Laboratories, Inc. | Test means and method for interference resistant determination of oxidizing substances |
US4444789A (en) * | 1980-05-30 | 1984-04-24 | University Of Georgia Research Foundation, Inc. | Use of 8-anilino-1-naphthalenesulfonate as a vaginal contraceptive |
JPS5856699A (ja) * | 1981-09-25 | 1983-04-04 | Maruho Kk | グアナ−ゼの迅速定量法 |
US5059394A (en) * | 1986-08-13 | 1991-10-22 | Lifescan, Inc. | Analytical device for the automated determination of analytes in fluids |
US4935346A (en) * | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US5049487A (en) * | 1986-08-13 | 1991-09-17 | Lifescan, Inc. | Automated initiation of timing of reflectance readings |
DE8710758U1 (de) * | 1987-08-06 | 1987-10-15 | Mollificio Fede di Dell'Oro P.I. Mario, Taceno, Como | Biegsamer Schlüsselring |
US5215890A (en) * | 1988-11-03 | 1993-06-01 | Spyros Theodoropulos | Chromogenic substrate to peroxidase enzymes |
WO1990006372A1 (en) * | 1988-12-01 | 1990-06-14 | Microprobe Corporation | Substrates for peroxidase assaying |
US5332662A (en) * | 1992-07-31 | 1994-07-26 | Syntex (U.S.A.) Inc. | Methods for determining peroxidatively active substances |
-
1993
- 1993-02-02 EP EP93300743A patent/EP0555045B1/en not_active Expired - Lifetime
- 1993-02-02 JP JP03619093A patent/JP3342077B2/ja not_active Expired - Lifetime
- 1993-02-02 AT AT93300743T patent/ATE159052T1/de active
- 1993-02-02 AU AU32191/93A patent/AU659525B2/en not_active Expired
- 1993-02-02 DE DE69314363T patent/DE69314363T2/de not_active Expired - Lifetime
- 1993-02-02 DK DK93300743.7T patent/DK0555045T3/da active
- 1993-02-02 CA CA002088652A patent/CA2088652C/en not_active Expired - Lifetime
- 1993-02-02 ES ES93300743T patent/ES2109429T3/es not_active Expired - Lifetime
- 1993-02-04 GR GR930100040A patent/GR1002975B/el not_active IP Right Cessation
-
1994
- 1994-05-19 US US08/245,940 patent/US5453360A/en not_active Expired - Lifetime
Also Published As
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JPH0611447A (ja) | 1994-01-21 |
AU659525B2 (en) | 1995-05-18 |
ATE159052T1 (de) | 1997-10-15 |
AU3219193A (en) | 1993-08-05 |
GR1002975B (el) | 1998-09-23 |
ES2109429T3 (es) | 1998-01-16 |
DE69314363D1 (de) | 1997-11-13 |
JP3342077B2 (ja) | 2002-11-05 |
DE69314363T2 (de) | 1998-02-19 |
EP0555045B1 (en) | 1997-10-08 |
DK0555045T3 (da) | 1998-03-16 |
EP0555045A1 (en) | 1993-08-11 |
CA2088652A1 (en) | 1993-08-04 |
US5453360A (en) | 1995-09-26 |
CA2088652C (en) | 2008-07-29 |
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