GB878284A - 1-o-tolyloxyethyl-4-phenyl-piperidine - Google Patents
1-o-tolyloxyethyl-4-phenyl-piperidineInfo
- Publication number
- GB878284A GB878284A GB2486859A GB2486859A GB878284A GB 878284 A GB878284 A GB 878284A GB 2486859 A GB2486859 A GB 2486859A GB 2486859 A GB2486859 A GB 2486859A GB 878284 A GB878284 A GB 878284A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tolyloxyethyl
- phenyl
- piperidine
- phenylpiperidine
- tetrahydropyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
The invention comprises 1-o-tolyloxyethyl-4-phenylpiperidine and its non-toxic pharmaceutically acceptable acid addition salts, and the preparation thereof by condensing a 2-o-tolyloxyethyl halide with 4-phenyl-, 1,2,3,6-tetrahydropyridine and hydrogenating the resulting product or by hydrogenating 4-phenyl-1,2,3,6-tetrahydropyridine to 4-phenyl-piperidine and condensing this with a 2-o-tolyloxyethyl halide.ALSO:Pharmaceutical compositions comprise 1-o-tolyloxy-4-phenylpiperidine in admixture with one or more solid or liquid pharmaceutically acceptable inert carriers. The compositions may be in the form of tablets, capsules or elixirs for oral administration or may be in a form useful for injection. It is also stated that the hydrochloride and tartrate of the base are particularly useful as hypotensive agents.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2486859A GB878284A (en) | 1959-07-20 | 1959-07-20 | 1-o-tolyloxyethyl-4-phenyl-piperidine |
CH822860A CH395992A (en) | 1959-07-20 | 1960-07-19 | Process for the preparation of 1- (o-tolyloxyethyl) -4-phenyl-piperidine |
BE593249A BE593249A (en) | 1959-07-20 | 1960-07-20 | New Piperidine Compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2486859A GB878284A (en) | 1959-07-20 | 1959-07-20 | 1-o-tolyloxyethyl-4-phenyl-piperidine |
Publications (1)
Publication Number | Publication Date |
---|---|
GB878284A true GB878284A (en) | 1961-09-27 |
Family
ID=10218527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2486859A Expired GB878284A (en) | 1959-07-20 | 1959-07-20 | 1-o-tolyloxyethyl-4-phenyl-piperidine |
Country Status (3)
Country | Link |
---|---|
BE (1) | BE593249A (en) |
CH (1) | CH395992A (en) |
GB (1) | GB878284A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0372776A2 (en) * | 1988-12-02 | 1990-06-13 | Pfizer Inc. | Arylpiperidine derivatives |
-
1959
- 1959-07-20 GB GB2486859A patent/GB878284A/en not_active Expired
-
1960
- 1960-07-19 CH CH822860A patent/CH395992A/en unknown
- 1960-07-20 BE BE593249A patent/BE593249A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0372776A2 (en) * | 1988-12-02 | 1990-06-13 | Pfizer Inc. | Arylpiperidine derivatives |
EP0372776A3 (en) * | 1988-12-02 | 1991-10-23 | Pfizer Inc. | Arylpiperidine derivatives |
Also Published As
Publication number | Publication date |
---|---|
CH395992A (en) | 1965-07-31 |
BE593249A (en) | 1961-01-20 |
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