GB651165A - Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacid - Google Patents
Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacidInfo
- Publication number
- GB651165A GB651165A GB18586/48A GB1858648A GB651165A GB 651165 A GB651165 A GB 651165A GB 18586/48 A GB18586/48 A GB 18586/48A GB 1858648 A GB1858648 A GB 1858648A GB 651165 A GB651165 A GB 651165A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methionine
- heated
- acetic acid
- product
- acidified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Methionine is obtained by reacting a -amino butyrolactone with sodium methyl mercaptide at between 150 DEG and 200 DEG C. and recovering the free acid from the resulting sodium salt. The lactone may be added to a suspension of the sodium methyl mercaptide in an inert solvent and the product formed then heated at 150 DEG to 200 DEG C. Free methionine may be obtained from the sodium salt formed by dissolving the latter in water and acidifying, e.g. with acetic acid to a pH value of 7. In examples: (1) a mixture of the reactants is heated to 180 DEG C. in an oil bath and after cooling the product is dissolved in water and acidified to a pH of 7 with acetic acid to yield methionine; (2) a -amino butyro lactone is added to a suspension of the mercaptide in xylene at 40 DEG C. A hard product is formed and after filtering off the xylene the residue is heated at 185 DEG C. in an oil bath. The melt is then dissolved in aqueous methanol and acidified with acetic acid as in (1) to form methionine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH651165X | 1947-07-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB651165A true GB651165A (en) | 1951-03-14 |
Family
ID=4526118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB18586/48A Expired GB651165A (en) | 1947-07-15 | 1948-07-10 | Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacid |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB651165A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0245231A1 (en) * | 1986-05-08 | 1987-11-11 | Monsanto Company | Process for the preparation of alkylthioalkanoate salts |
US5175310A (en) * | 1990-03-16 | 1992-12-29 | Elf Atochem North America, Inc. | Process for producing alkylthio- and arylthio-substituted carboxylic acids and their thioesters |
US7884240B2 (en) * | 2006-01-28 | 2011-02-08 | Evonik Degussa Gmbh | Method for production of methionine from homoserine |
FR2965561A1 (en) * | 2010-10-05 | 2012-04-06 | Adisseo France Sas | PROCESS FOR PREPARING AMINO ACID FROM 2-AMINOBUTYROLACTONE |
-
1948
- 1948-07-10 GB GB18586/48A patent/GB651165A/en not_active Expired
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0245231A1 (en) * | 1986-05-08 | 1987-11-11 | Monsanto Company | Process for the preparation of alkylthioalkanoate salts |
US4777289A (en) * | 1986-05-08 | 1988-10-11 | Monsanto Company | Process for the preparation of alkylthioalkanoate salts |
US5175310A (en) * | 1990-03-16 | 1992-12-29 | Elf Atochem North America, Inc. | Process for producing alkylthio- and arylthio-substituted carboxylic acids and their thioesters |
US7884240B2 (en) * | 2006-01-28 | 2011-02-08 | Evonik Degussa Gmbh | Method for production of methionine from homoserine |
FR2965561A1 (en) * | 2010-10-05 | 2012-04-06 | Adisseo France Sas | PROCESS FOR PREPARING AMINO ACID FROM 2-AMINOBUTYROLACTONE |
WO2012045967A1 (en) * | 2010-10-05 | 2012-04-12 | Adisseo France S.A.S. | Method for preparing an amino acid from 2-aminobutyrolactone |
CN103153943A (en) * | 2010-10-05 | 2013-06-12 | 安迪苏法国联合股份有限公司 | Method for preparing an amino acid from 2-aminobutyrolactone |
US8853428B2 (en) | 2010-10-05 | 2014-10-07 | Adisseo France S.A.S. | Method for preparing an amino acid from 2 aminobutyrolactone |
RU2561602C2 (en) * | 2010-10-05 | 2015-08-27 | Адиссео Франс С.А.С. | Method of producing amino acid from 2-aminobutyrolactone |
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